Association of Escherichia coli with the small intestinal epithelium. I. Comparison of enteropathogenic and nonenteropathogenic porcine strains in pigs.

abstract：:Most Helicobacter pylori strains express the BabA adhesin, which binds to ABO/Leb blood group antigens on gastric mucin and epithelial cells and is found more commonly in strains that cause peptic ulcers or gastric cancer, rather than asymptomatic infection. We and others have previously reported that in mice, gerbils...

journal_title：Infection and immunity

authors： Hansen LM,Gideonsson P,Canfield DR,Borén T,Solnick JV

更新日期：2017-05-23 00:00:00

abstract：:Escherichia coli is a versatile pathogen causing millions of infections in humans every year. This bacterium can form multicellular aggregates when it expresses a self-associating protein, antigen 43 (Ag43), on its surface. We have discovered that Ag43-expressing E. coli cells are efficiently taken up by human defense...

journal_title：Infection and immunity

authors： Fexby S,Bjarnsholt T,Jensen PØ,Roos V,Høiby N,Givskov M,Klemm P

更新日期：2007-01-01 00:00:00

abstract：:Differences in infection kinetics and host response between Burkholderia multivorans and Burkholderia cenocepacia were demonstrated in a pulmonary infection model in BALB/c mice. B. multivorans persisted in the lung, while B. cenocepacia was cleared. Indirect immunofluorescence and electron microscopy of B. multivoran...

journal_title：Infection and immunity

authors： Chu KK,MacDonald KL,Davidson DJ,Speert DP

更新日期：2004-10-01 00:00:00

abstract：:A ruthenium red-staining capsule was observed on two pathogenic strains, but not on one nonpathogenic strain of Mycoplasma gallisepticum. The capsule appeared to mediate cytadsorption of mycoplasmas to the chicken tracheal epithelium without evidence of membrane fusion. No relationship was seen between the presence of...

journal_title：Infection and immunity

authors： Tajima M,Yagihashi T,Miki Y

更新日期：1982-05-01 00:00:00

abstract：:The attachment of radioisotope-labeled Mycoplasma pneumoniae to hamster tracheal rings in organ culture was examined by radioautography and liquid scintillation counting. Radioautographs of individual rings exposed for 8 h to (3H) thymidine-labeled virulent M. pneumoniae revealed a dense extracellular collection of em...

journal_title：Infection and immunity

authors： Powell DA,Hu PC,Wilson M,Collier AM,Baseman JB

更新日期：1976-03-01 00:00:00

abstract：:Immunochemical analyses of soluble antigens derived from microaerophilous stationary phase cultures of Babesia bovis demonstrated that at least three parasite antigens were released in vitro. These antigens have molecular weights within the range of 37,000 to 40,000, fast electrophoretic mobility in the albumin and al...

journal_title：Infection and immunity

authors： James MA,Levy MG,Ristic M

更新日期：1981-01-01 00:00:00

abstract：:Staphylococcus aureus is a prominent human pathogen and a leading cause of community- and hospital-acquired bacterial infections worldwide. Herein, we describe the identification and characterization of the S. aureus 67.6-kDa hypothetical protein, named for the surface factor promoting resistance to oxidative killing ...

journal_title：Infection and immunity

authors： Malachowa N,Kohler PL,Schlievert PM,Chuang ON,Dunny GM,Kobayashi SD,Miedzobrodzki J,Bohach GA,Seo KS

更新日期：2011-01-01 00:00:00

abstract：:Trypanosoma cruzi is a protozoan parasite that can initiate mucosal infection after conjunctival exposure. The anatomical route of T. cruzi invasion and spread after conjunctival parasite contamination remains poorly characterized. In the present work we have identified the sites of initial invasion and replication af...

journal_title：Infection and immunity

authors： Giddings OK,Eickhoff CS,Smith TJ,Bryant LA,Hoft DF

更新日期：2006-10-01 00:00:00

abstract：:Immunization of BALB/c mice with a plasmid containing the gene for Trypanosoma cruzi trans-sialidase (TS) induced antibodies that inhibited TS enzymatic activity, CD4+ Th1 and CD8+ Tc1 cells, and protective immunity against infection. We used this model to obtain basic information on the requirement of CD4 or CD8 or B...

journal_title：Infection and immunity

authors： Fujimura AE,Kinoshita SS,Pereira-Chioccola VL,Rodrigues MM

更新日期：2001-09-01 00:00:00

abstract：:In experiments described herein, it was observed that guinea pigs with delayed-type hypersensitivity to tuberculoproteins under various experimental conditions, with or without passive transfer of serum from immune donors, manifested no acquired immunity against aerogenically induced tuberculosis. These results are di...

journal_title：Infection and immunity

authors： Reggiardo Z,Middlebrook G

更新日期：1974-05-01 00:00:00

abstract：:Macrophages can undergo apoptosis after infection with Mycobacterium tuberculosis. This macrophage response deprives the bacillus of its niche cell and supports the host response through better antigen presentation. The intracellular pathways of apoptosis that elaborate this macrophage response are not well understood...

journal_title：Infection and immunity

authors： O'Sullivan MP,O'Leary S,Kelly DM,Keane J

更新日期：2007-04-01 00:00:00

abstract：:Differences in acid tolerance among representative oral streptococci were found to be related more closely to the dynamic permeabilities of the bacteria to protons than to differences in the sensitivities of cell membranes to gross damage caused by environmental acidification. For Streptococcus mutans GS-5, Streptococ...

journal_title：Infection and immunity

authors： Bender GR,Sutton SV,Marquis RE

更新日期：1986-08-01 00:00:00

abstract：:The present study was performed to determine whether Histoplasma capsulatum (yeast phase) is able to activate the alternative complement pathway. H. capsulatum yeasts were shown to consume C3 in C4-deficient guinea pig serum. Immunoelectrophoretic conversion of alternative pathway component factor B confirmed that C3 ...

journal_title：Infection and immunity

authors： Ratnoff WD,Pepple JM,Winkelstein JA

更新日期：1980-10-01 00:00:00

abstract：:The eib genes of Escherichia coli encode surface-exposed proteins which bind immunoglobulins (Ig) such as the Fc fragment of human IgG (IgG Fc) in a nonimmune manner. The Eib proteins belong to a family which includes YadA of Yersinia, UspA2 of Moraxella, and DsrA of Haemophilus ducreyi. This family of surface-exposed...

journal_title：Infection and immunity

authors： Sandt CH,Hill CW

更新日期：2001-12-01 00:00:00

abstract：:Monoclonal antibodies (MAbs) specific for Plasmodium falciparum rhoptry-associated protein 1 (RAP-1) were generated and tested for inhibition of parasite growth in vitro. The majority of indirect immunofluorescence assay (IFA)-positive MAbs raised against recombinant RAP-1 positions 23 to 711 (rRAP-1(23-711)) recogniz...

journal_title：Infection and immunity

authors： Moreno R,Pöltl-Frank F,Stüber D,Matile H,Mutz M,Weiss NA,Pluschke G

更新日期：2001-04-01 00:00:00

abstract：:Neutralizing antibodies were raised in mice that had been inoculated repeatedly with moderate quantities of human leukocyte interferon highly purified by affinity chromatography on immobilized anti-interferon globulins. Interferon preparations of lesser purity sensitized the mice to subsequent inoculations of interfer...

journal_title：Infection and immunity

authors： Dalton BJ,Ogburn CA,Paucker K

更新日期：1978-02-01 00:00:00

abstract：:The serum antibody response and four different cellular immune responses (cytotoxic T cells, delayed-type hypersensitivity T cells, natural killer cells, and cytotoxic macrophage levels) induced in CBA/H mice were measured at different times after intranasal inoculation of a cold-adapted (ca) variant of influenza A vi...

journal_title：Infection and immunity

authors： Mak NK,Zhang YH,Ada GL,Tannock GA

更新日期：1982-10-01 00:00:00

abstract：:During bacterial infection of the bovine mammary gland, large numbers of leukocytes migrate into the udder, resulting in the establishment of a host response against the pathogen. Currently, the specific leukocyte populations mediating this immune response are not well defined. In the studies described here, we analyz...

journal_title：Infection and immunity

authors： Soltys J,Quinn MT

更新日期：1999-12-01 00:00:00

abstract：:The salivary and serum immune responses to orally administered glucosyltransferase antigen complex from Streptococcus mutants strain 6715 were investigated in hamsters. All enzyme-linked immunosorbent assay was used to measure the antibody quantity and isotype, and a [14C]glucosyl-labeled sucrose incorporation assay w...

journal_title：Infection and immunity

authors： Smith DJ,Taubman MA,Ebersole JL

更新日期：1980-05-01 00:00:00

abstract：:Serotype b-specific polysaccharide antigen (SPA) of Actinobacillus actinomycetemcomitans Y4 consists of D-fucose and L-rhamnose. To clarify the role of SPA in phagocytosis of the organism by human polymorphonuclear leukocytes (PMNs), monoclonal antibodies (MAbs) against SPA and SPA-defective mutants, which were constr...

journal_title：Infection and immunity

authors： Yamaguchi N,Kawasaki M,Yamashita Y,Nakashima K,Koga T

更新日期：1995-12-01 00:00:00

abstract：:Haemophilus ducreyi previously has been shown to inhibit the phagocytosis of both secondary targets and itself by certain cells in vitro. Wild-type H. ducreyi strain 35000HP contains two genes, lspA1 and lspA2, whose encoded protein products are predicted to be 456 and 543 kDa, respectively. An isogenic mutant of H. d...

journal_title：Infection and immunity

authors： Vakevainen M,Greenberg S,Hansen EJ

更新日期：2003-10-01 00:00:00

abstract：:The purpose of our experiment was to evaluate the destructive potential of a strain of Actinomyces viscosus on the periodontium of sensitized rodents, describing the induced lesions on the basis of quantitative cytology. The experimental design comprised in principle the following procedures. Young germfree rats were ...

journal_title：Infection and immunity

authors： Guggenheim B,Schroeder HE

更新日期：1974-09-01 00:00:00

abstract：:The antigenically conserved proteins of Treponema pallidum subsp. pallidum and four nonpathogenic cultivatable treponemes were investigated by phase partitioning with the nonionic detergent Triton X-114 and immunoblot analysis. None of the T. pallidum integral membrane proteins identified by phase partitioning (deterg...

journal_title：Infection and immunity

authors： Radolf JD,Norgard MV

更新日期：1988-07-01 00:00:00

abstract：:The hydrolysis of urea by ureases of oral bacteria in dental plaque can cause a considerable increase in plaque pH, which can inhibit the development of dental caries. There is also indirect evidence that urea metabolism may promote the formation of calculus and that ammonia release from urea could exacerbate periodon...

journal_title：Infection and immunity

authors： Morou-Bermudez E,Burne RA

更新日期：2000-12-01 00:00:00

abstract：:Phagosome acidification is an important component of the microbicidal response by infected eukaryotic cells. Thus, intracellular pathogens that reside within phagosomes must either block phagosome acidification or be able to survive at low pH. In this work, we studied the effect of phagosomal acidification on the surv...

journal_title：Infection and immunity

authors： Steele-Mortimer O,St-Louis M,Olivier M,Finlay BB

更新日期：2000-09-01 00:00:00

abstract：:Plasmodium falciparum's ability to invade erythrocytes is essential for its survival within the human host. Immune mechanisms that impair this ability are therefore expected to contribute to immunity against the parasite. Plasma of humans who are naturally exposed to malaria has been shown to have growth-inhibitory ac...

journal_title：Infection and immunity

authors： Rono J,Färnert A,Olsson D,Osier F,Rooth I,Persson KE

更新日期：2012-05-01 00:00:00

abstract：:Streptococcus sanguis 804 (NCTC 10904) was grown ih batch culture at constant pH. and the glucosyltransferase activity of the supernatant was assayed over a 40-h growth period. The optimum pH for enzyme production was 7.0 to 7.2. During growth of the culture, three reproducible phases of enzyme activity were observed....

journal_title：Infection and immunity

authors： Beeley JA,Black PM

更新日期：1977-01-01 00:00:00

abstract：:The primary antibody response of BALB/c splenocytes to sheep erythrocytes in vitro was suppressed by infection with Friend leukemia virus (FLV), with the response capacity decreasing with increasing duration of infection. The acquisition of normal antibody responses was amplified by macrophage-produced antibody respon...

journal_title：Infection and immunity

authors： Butler RC,Frier JM,Chapekar MS,Graham MO,Friedman H

更新日期：1983-03-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) is a by-product of glycerol metabolism in mycoplasmas and has been shown to cause cytotoxicity for cocultured eukaryotic cells. There appears to be selective pressure for mycoplasmas to retain the genes needed for glycerol metabolism. This has generated interest and speculation as to their fun...

journal_title：Infection and immunity

authors： Szczepanek SM,Boccaccio M,Pflaum K,Liao X,Geary SJ

更新日期：2014-12-01 00:00:00

abstract：:ATP and UTP have been proposed for use as therapeutic treatment of the abnormal ion transport in the airway epithelium in cystic fibrosis (CF), the most characteristic feature of which is permanent infection by Pseudomonas aeruginosa. As for diverse gram-negative bacteria, this pathogenic bacterium accumulates diffusi...

journal_title：Infection and immunity

authors： Saleh A,Figarella C,Kammouni W,Marchand-Pinatel S,Lazdunski A,Tubul A,Brun P,Merten MD

更新日期：1999-10-01 00:00:00