Glucosyltransferase production by Streptococcus sanguis 804 (NCTC 10904).

abstract：:Streptococcus mutans produces several enzymes which metabolize sucrose. Three glucosyltransferase genes (gtfB, gtfC, and gtfD) and a single fructosyltransferase gene (ftf) encode enzymes which are important in formation of exopolysaccharides. Mutants of S. mutans V403 carrying single and multiple mutations of the gtfB...

journal_title：Infection and immunity

authors： Munro C,Michalek SM,Macrina FL

更新日期：1991-07-01 00:00:00

abstract：:Pneumonia due to Gram-negative bacteria is associated with high mortality. Acinetobacter baumannii is a Gram-negative bacterium that is associated with hospital-acquired and ventilator-associated pneumonia. Bacteria have been described to release outer membrane vesicles (OMVs) that are capable of mediating systemic in...

journal_title：Infection and immunity

authors： Marion CR,Lee J,Sharma L,Park KS,Lee C,Liu W,Liu P,Feng J,Gho YS,Dela Cruz CS

更新日期：2019-08-21 00:00:00

abstract：:Lactoferrin (LF) is a multifunctional immunoregulatory protein that has been associated with host defense at mucosal surfaces through its antibacterial properties. The antibacterial and anti-inflammatory properties of LF were further explored with an animal model of experimental urinary tract infection. Bovine LF (bLF...

journal_title：Infection and immunity

authors： Håversen LA,Engberg I,Baltzer L,Dolphin G,Hanson LA,Mattsby-Baltzer I

更新日期：2000-10-01 00:00:00

abstract：:Pseudomonas aeruginosa utilizes a number of distinct pathways to secrete proteins that play various roles during infection. These include the type II secretion system, which is responsible for the secretion of the majority of exoproducts into the surrounding environment, including toxins and degradative enzymes. In co...

journal_title：Infection and immunity

authors： Lee VT,Smith RS,Tümmler B,Lory S

更新日期：2005-03-01 00:00:00

abstract：:The disruption of a specific gene in Candida albicans is commonly used to determine the function of the gene product. We disrupted AAF1, a gene of C. albicans that causes Saccharomyces cerevisiae to flocculate and adhere to endothelial cells. We then characterized multiple heterozygous and homozygous mutants. These nu...

journal_title：Infection and immunity

authors： Rieg G,Fu Y,Ibrahim AS,Zhou X,Filler SG,Edwards JE Jr

更新日期：1999-07-01 00:00:00

abstract：:When type I Candida stellatoidea is plated onto sucrose agar at levels in excess of 10(8) cells, some isolates spontaneously form sucrose-positive colonies. These isolates do not display typical type I phenotypes but instead exhibit phenotypes intermediate between type I C. stellatoidea and C. albicans. Also, this phe...

journal_title：Infection and immunity

authors： Wickes BL,Golin JE,Kwon-Chung KJ

更新日期：1991-05-01 00:00:00

abstract：:Three-month-old male Crl:CD1(ICR)BR and C3H/HeJ mice were fed chow containing Candida albicans for 14 days, while similar control mice were fed regular food. Stool cultures were done for all mice before and after administration of the special diet. Stool cultures were repeated 48 h, 1 week, and 1 and 3 months after st...

journal_title：Infection and immunity

authors： Samonis G,Anaissie EJ,Rosenbaum B,Bodey GP

更新日期：1990-06-01 00:00:00

abstract：:Nine goats were injected transthoracically with Pasteurella haemolytica A1 to determine if an extracellular bacterial enzyme, neuraminidase, was produced in vivo during infection with this organism. The principal group of goats (n = 9) each received 1 ml of 7.25 x 10(5) live P. haemolytica A1 cells in polyacrylate bea...

journal_title：Infection and immunity

authors： Straus DC,Purdy CW

更新日期：1994-10-01 00:00:00

abstract：:Lipopolysaccharide (LPS) structure impacts the bactericidal action of cationic peptides, such as polymyxin B (PMB), and sensitivity to killing by normal human serum (NHS). Cultivation of different subspecies strains of Yersinia pestis isolated from unrelated geographic origins at various temperatures (mammals, 37 degr...

journal_title：Infection and immunity

authors： Anisimov AP,Dentovskaya SV,Titareva GM,Bakhteeva IV,Shaikhutdinova RZ,Balakhonov SV,Lindner B,Kocharova NA,Senchenkova SN,Holst O,Pier GB,Knirel YA

更新日期：2005-11-01 00:00:00

abstract：:Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections. These bacteria undertake a multistage infection cycle involving invasion of and proliferation within urinary tract epithelial cells, leading to the rupture of the host cell and dispersal of the bacteria, some of which have a highly...

journal_title：Infection and immunity

authors： Iosifidis G,Duggin IG

更新日期：2020-08-19 00:00:00

abstract：:Bordetella pertussis extract that contained adenylate cyclase toxin produced large increases in human neutrophil cyclic AMP levels and inhibited their oxidative burst, as reflected by luminol-enhanced chemiluminescence and superoxide release. The adenylate cyclase toxin-containing extract blocked neutrophil-mediated i...

journal_title：Infection and immunity

authors： Galgiani JN,Hewlett EL,Friedman RL

更新日期：1988-04-01 00:00:00

abstract：:Bacillary angiomatosis (BA), one of the many clinical manifestations resulting from infection with the facultative intracellular bacterium Bartonella henselae, is characterized by angiogenic lesions. Macrophages have been identified as important effector cells contributing to the angiogenic process during B. henselae ...

journal_title：Infection and immunity

authors： McCord AM,Burgess AW,Whaley MJ,Anderson BE

更新日期：2005-09-01 00:00:00

abstract：:The role of the alternative sigma factor sigma(B) in Staphylococcus epidermidis was investigated by the construction, complementation, and characterization of a sigB deletion mutant. Electrophoretic analyses confirmed a profound influence of sigma(B) on the expression of exoproteins and cytoplasmic proteins. Detailed ...

journal_title：Infection and immunity

authors： Kies S,Otto M,Vuong C,Götz F

更新日期：2001-12-01 00:00:00

abstract：:An effective vaccine for Vibrio cholerae is not yet available for use in the developing world, where the burden of cholera disease is highest. Characterizing the proteins that are expressed by V. cholerae in the human host environment may provide insight into the pathogenesis of cholera and assist with the development...

journal_title：Infection and immunity

authors： LaRocque RC,Krastins B,Harris JB,Lebrun LM,Parker KC,Chase M,Ryan ET,Qadri F,Sarracino D,Calderwood SB

更新日期：2008-09-01 00:00:00

abstract：:The rationale for the present study was to determine how different species of bacteria interact with cells of the human meninges in order to gain information that would have broad relevance to understanding aspects of the innate immune response in the brain. Neisseria lactamica is an occasional cause of meningitis in ...

journal_title：Infection and immunity

authors： Fowler MI,Yin KY,Humphries HE,Heckels JE,Christodoulides M

更新日期：2006-11-01 00:00:00

abstract：:Two hybrid clones producing monoclonal antibodies (MAbs) raised against the purified enterotoxic hemolysin-phospholipase C (HlyPC) bifunctional molecule of a Vibrio cholerae O139 strain were used to study its enterotoxicity in relation to its hemolytic and enzymatic activities. Fab fragments of MAbs from ascites produ...

journal_title：Infection and immunity

authors： Pal S,Datta A,Nair GB,Guhathakurta B

更新日期：1998-08-01 00:00:00

abstract：:Virulence of the fungal pathogen Aspergillus fumigatus is in part based on the saprophytic lifestyle that this mold has evolved. A crucial function for saprophytism resides in secreted proteases that allow assimilation of proteinaceous substrates. The impact of extracellular proteolytic activities on the pathogenesis ...

journal_title：Infection and immunity

authors： Bergmann A,Hartmann T,Cairns T,Bignell EM,Krappmann S

更新日期：2009-09-01 00:00:00

abstract：:The present study was performed to determine whether Histoplasma capsulatum (yeast phase) is able to activate the alternative complement pathway. H. capsulatum yeasts were shown to consume C3 in C4-deficient guinea pig serum. Immunoelectrophoretic conversion of alternative pathway component factor B confirmed that C3 ...

journal_title：Infection and immunity

authors： Ratnoff WD,Pepple JM,Winkelstein JA

更新日期：1980-10-01 00:00:00

abstract：:One- to three-day-old guinea pigs were inoculated intranasally with the chlamydial agent of guinea pig inclusion conjunctivitis. Physical signs of infection included a marked increase in respiration rate on days 5 to 10 of infection and radiographic evidence of pneumonia on day 6. When animals were killed at various t...

journal_title：Infection and immunity

authors： Rank RG,Hough AJ Jr,Jacobs RF,Cohen C,Barron AL

更新日期：1985-04-01 00:00:00

abstract：:A total of 133 Listeria monocytogenes isolates were characterized by ribotyping and allelic analysis of the virulence genes hly, actA, and inlA to uncover linkages between independent phylogenetic and specific virulence markers. PCR-restriction fragment length polymorphisms revealed 8 hly, 11 inl4, and 2 actA alleles....

journal_title：Infection and immunity

authors： Wiedmann M,Bruce JL,Keating C,Johnson AE,McDonough PL,Batt CA

更新日期：1997-07-01 00:00:00

abstract：:Streptococcus pneumoniae infection leads to multifold increases in sialyltransferase, galactosyltransferase, alpha 2-fucosyltransferase, and alpha 3-fucosyltransferase activity of rat liver. Such changes may reflect an increased demand for glycosylation of acute-phase proteins synthesized and secreted by the liver dur...

journal_title：Infection and immunity

authors： Canonico PG,Little JS,Powanda MC,Bostian KA,Beisel WR

更新日期：1980-07-01 00:00:00

abstract：:Haemophilus influenzae type b infection of immersed and air interface organ cultures for 24 h caused significant epithelial damage. Bacterial association with mucus, damaged epithelium, and unciliated cells was significantly higher in air interface than immersed organ cultures, and total bacterial association was 55.8...

journal_title：Infection and immunity

authors： Jackson AD,Cole PJ,Wilson R

更新日期：1996-06-01 00:00:00

abstract：:The effect of bile on the expression of cholera toxin (CT) and the major subunit of the toxin-coregulated pilus (TcpA) and on motility was examined in the Vibrio cholerae O1 classical-biotype strains 0395 and 569B. Although the motility of the cells increased significantly in the presence of bile, transcription of the...

journal_title：Infection and immunity

authors： Gupta S,Chowdhury R

更新日期：1997-03-01 00:00:00

abstract：:Poly-N-acetyl-glucosamine (PNAG) is a staphylococcal surface polysaccharide influencing biofilm formation that is also under investigation for its vaccine potential. Antibodies that bind to PNAG with either low (<15%) or high (>90%) levels of acetate are superior at opsonic and protective activity compared with antibo...

journal_title：Infection and immunity

authors： Cerca N,Jefferson KK,Maira-Litrán T,Pier DB,Kelly-Quintos C,Goldmann DA,Azeredo J,Pier GB

更新日期：2007-07-01 00:00:00

abstract：:In gram-negative sepsis, the activation of polymorphonuclear leukocytes (PMN) by lipopolysaccharide (LPS) and the resulting production of superoxide and other oxygen radicals may be an important cause of tissue damage. A suppression of the PMN response to LPS stimulation would be therapeutically beneficial. The aim of...

journal_title：Infection and immunity

authors： Wagner DR,Heinrich D

更新日期：1994-10-01 00:00:00

abstract：:Filarial infection is initiated by mosquito-derived third-stage larvae (L3) deposited on the skin that transit through the epidermis, which contains Langerhans cells (LC) and keratinocytes (KC), among other cells. This earliest interaction between L3 and the LC likely conditions the priming of the immune system to the...

journal_title：Infection and immunity

authors： Boyd A,Bennuru S,Wang Y,Sanprasert V,Law M,Chaussabel D,Nutman TB,Semnani RT

更新日期：2013-05-01 00:00:00

abstract：:Colonization of the large bowel of healthy infants by Clostridium difficile was studied. Feces were collected from five breast-fed aand five formula-fed infants throughout the first year of life, and levels of C. difficile were quantitated. Three breast-fed and five formula-fed infants were colonized for periods of be...

journal_title：Infection and immunity

authors： Stark PL,Lee A,Parsonage BD

更新日期：1982-03-01 00:00:00

abstract：:The EUO gene (for early upstream open reading frame) of Chlamydia psittaci was previously found to be transcribed better at 1 than at 24 h postinfection. We found that the EUO gene encodes a minor protein that is expressed within 1 h of infection of host cells with C. psittaci 6BC but that protein quantity peaks durin...

journal_title：Infection and immunity

authors： Zhang L,Douglas AL,Hatch TP

更新日期：1998-03-01 00:00:00

abstract：:In general there is a poor correlation between serum lipopolysaccharide (LPS; the biologically active constituent of endotoxin) levels and mortality in septic patients. The objective of this study was to determine if chemical, structural, or biological differences among LPS from different clinical isolates of gram-neg...

journal_title：Infection and immunity

authors： Luchi M,Morrison DC

更新日期：2000-04-01 00:00:00

abstract：:The salivary and serum immune responses to orally administered glucosyltransferase antigen complex from Streptococcus mutants strain 6715 were investigated in hamsters. All enzyme-linked immunosorbent assay was used to measure the antibody quantity and isotype, and a [14C]glucosyl-labeled sucrose incorporation assay w...

journal_title：Infection and immunity

authors： Smith DJ,Taubman MA,Ebersole JL

更新日期：1980-05-01 00:00:00