Abstract:
:The cellular localisation of benzodiazepine receptors was studied. Kainic acid induced neuronal lesions (2 x 0.25-2 x 2 micrograms; 2-26 days in rat cerebellum decreased specific binding of [3H]flunitrazepam down to 35% of controls. Specific binding of [3H]flunitrazepam was also decreased (to 80% of controls) in the cerebllum of mutant nervous mouse (nr/nr) where Purkinje cells are degenerated but in the mutant weaver mouse where granule cells are degenerated. These results show that benzodiazepine receptors are located mainly on neurons; both on Purkinje cells and other neurons, but not to a great extent on granule cells.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Braestrup C,Nielsen M,Biggio G,Squires RFdoi
10.1016/0304-3940(79)91497-6subject
Has Abstractpub_date
1979-08-01 00:00:00pages
219-24issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(79)91497-6journal_volume
13pub_type
杂志文章abstract::Estrogen effects on pineal secretion of melatonin are controversial. Some feel that estrogen inhibits melatonin output in vitro but not in vivo. Melatonin levels vary with the age in chickens where circulating estrogen levels also vary. Laying hens have minimal melatonin levels and maximal serum iron concentrations. T...
journal_title:Neuroscience letters
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doi:10.1016/0304-3940(93)90836-a
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(86)90075-3
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2005-01-20 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1988-05-16 00:00:00
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journal_title:Neuroscience letters
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更新日期:1980-06-01 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2012-09-06 00:00:00
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journal_title:Neuroscience letters
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更新日期:1988-09-23 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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更新日期:2004-01-02 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2013-12-17 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1985-05-23 00:00:00
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journal_title:Neuroscience letters
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更新日期:2014-06-06 00:00:00