Abstract:
:N-Methyl-D-aspartate (NMDA), quisqualate, kainate and potassium increased, in a dose-dependent manner, the efflux of radioactivity from rat cerebral cortex minislices preincubated with [3H]choline. Ketamine (1-5 microM) and magnesium (0.1-1 mM) reduced only the release evoked by NMDA. The non-parallel shift of the NMDA dose-response curve suggests that ketamine is not acting as a competitive antagonist of NMDA.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Lodge D,Johnston GAdoi
10.1016/0304-3940(85)90271-xsubject
Has Abstractpub_date
1985-05-23 00:00:00pages
371-5issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(85)90271-Xjournal_volume
56pub_type
杂志文章abstract::In non-diabetic mice, s.c. injection of formalin to the hindpaw had a biphasic effect: an immediate nociceptive response (first-phase) followed by a tonic response (second-phase). However, only the immediate nociceptive response was observed in diabetic mice. The duration of the first-phase response was significantly ...
journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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更新日期:2011-01-20 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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更新日期:1988-01-22 00:00:00
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更新日期:2010-03-08 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(85)80065-3
更新日期:1985-03-15 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1994-01-03 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1998-05-08 00:00:00