Abstract：
:It is argued that studying the drinking patterns of adolescents can add much to our understanding of alcohol use. The present paper hypothesises that heavy drinkers will be experiencing more stress than light, moderate or non-drinkers and that consequently, they will perceive themselves as doing worse in school and will report more conflict with their parents. It is predicted that heavy drinkers will have failed to learn norms controlling alcohol use. It is anticipated that social norms are learnt through controlled drinking in a family setting and thus it is predicted that heavy drinkers will be less likely to drink with their parents and more likely to drink with their peers, than other groups of drinkers. It is argued that heavy drinkers will be more involved in peer group activities and less concerned about their health, than light, moderate or non-drinkers. These hypotheses were tested in a survey of 10 579 British adolescents (5068 boys), and support was found for all but one of these hypothesis (i.e., the hypothesis that heavy drinkers would be less likely to drink with their parents than light or moderate drinkers).
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Budd RJ,Eiser JR,Morgan M,Gammage Pdoi
10.1016/0376-8716(85)90113-9subject
Has Abstractpub_date
1985-11-01 00:00:00pages
145-57issue
2eissn
0376-8716issn
1879-0046pii
0376-8716(85)90113-9journal_volume
16pub_type
杂志文章abstract：:This double-blind, randomized, placebo-controlled clinical trial evaluated the impact on withdrawal symptoms of (i) combining naltrexone with a 4-day buprenorphine taper for short opioid detoxification (NB Group), compared to (ii) using a 4-day buprenorphine taper alone, followed by naltrexone on day 8 (PB Group). Sub...
journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0376-8716(99)00033-2
更新日期：1999-10-01 00:00:00
abstract：:This study substantiates previous reports that low platelet monoamine oxidase (MAO) activity is associated with alcoholism. Catechol-o-methyltransferase (COMT) activity in erythrocytes of alcoholics did not differ from that of controls. In 20 male alcoholics low platelet MAO activity was found during the first 3 days ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(83)90056-x
更新日期：1983-08-01 00:00:00
abstract：:Neonates born to opioid-maintained mothers are at risk of developing neonatal abstinence syndrome (NAS), which often requires pharmacological treatment. This study examined the effect of opioid maintenance treatment on the incidence and timing of NAS, and compared two different NAS treatments (phenobarbital versus mor...
journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章
doi：10.1016/j.drugalcdep.2006.08.024
更新日期：2007-03-16 00:00:00
abstract：:Research has identified children of alcoholics (COAs) as a population at increased risk for developing substance use problems. Genetic studies support the Al allele of the D2 dopamine receptor gene (DRD2) as a risk marker for alcoholism and substance use disorders. In this study, substance use was assessed in 48 adole...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2005.03.005
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND:Previously reported comorbidity between schizophrenia and substance use may be explained by shared underlying risk factors, such as genetic background. The aim of the present longitudinal study was to investigate how a genetic predisposition to schizophrenia was associated with patterns of substance use (can...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2018.05.024
更新日期：2018-09-01 00:00:00
abstract：:Administrative data provide a rich resource for improving our understanding of individuals with substance use disorders. The validation of administrative proxies for moderate or high risk alcohol or drug (AOD) use could enhance the ability to carry out rigorous observational research (for example, for use in the const...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2010.03.013
更新日期：2010-09-01 00:00:00
abstract：:Tyrosine hydroxylase (TH) is the rate-limiting enzyme in catecholamine biosynthesis. Previously published results have established that chronic cocaine administration (30-45 mg/kg per day, 10-14 days) resulted in an upregulation of TH gene expression in dopaminergic pathways of rats. The present studies tested the eff...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(00)00119-8
更新日期：2000-12-22 00:00:00
abstract：BACKGROUND:A recent systematic review observed that HIV prevalence amongst injectors is negligible (<1%) below a threshold HCV prevalence of 30%, but thereafter increases with HCV prevalence. We explore whether a model can reproduce these trends, what determines different epidemiological profiles and how this affects i...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2011.10.032
更新日期：2012-06-01 00:00:00
abstract：AIMS:Though the introduction of office-based buprenorphine has greatly contributed to stem the HIV epidemic since 1995, concerns have been raised about the intravenous use of buprenorphine even in patients on substitution treatment. The aim of this study was to identify which factors are predictive of buprenorphine inj...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2008.03.025
更新日期：2008-09-01 00:00:00
abstract：BACKGROUND:Studies of drinking drivers in alcohol-related crashes have shown that high breath-alcohol concentrations (BrACs) are associated with illegal drug use. Until the 2007 National Roadside Survey (NRS), the prevalence of drugs among drinking drivers on U.S. roads was unknown. Using NRS data, we explore how many ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2012.11.007
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Amphetamine abuse is increasing worldwide, and the occurrence of amphetamine-induced (AI) psychiatric issues further complicates treatment. In response, the DSM 5 has introduced the classification of amphetamine-induced obsessive-compulsive disorders (AI-OCD), though little has been published on either its p...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.12.034
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Relatively little is known about factors that may lead to the development of a substance use disorder (SUD), across a range of drug classes. This study aimed to identify factors that predict the likelihood of transition from use to SUD and the speed with which this may occur at the population level, with a f...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2018.10.010
更新日期：2019-01-01 00:00:00
abstract：:The pre-treatment social stability score (combined economic-familial-residential scales), indicating whether the patients were comparatively integrated or disintegrated socially, was found to be of greater prognostic value regarding post-treatment drinking than was information about whether they received full, part or...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(77)90009-6
更新日期：1977-03-01 00:00:00
abstract：BACKGROUND:Illicit drug users account for the majority of cases of HCV infection in the developed world, but few have received treatment. METHODS:We evaluated barriers to initiating HCV treatment -- including general treatment willingness -- and factors associated with these among HCV infected illicit drug users. Part...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2007.09.008
更新日期：2008-01-11 00:00:00
abstract：BACKGROUND:Heart rate variability (HRV) is of interest to researchers due to its potential utility as a marker for both physiological and psychological stress. Sympatholytics are used to treat opioid withdrawal, but little information about the parasympathetic system's role in mediating withdrawal symptoms exists. The ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2019.06.040
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Previous research has demonstrated how negative affect (i.e., depression, anxiety, stress) is often a correlate of and precursor to nicotine dependence. Although recent evidence shows a gradual decline in tobacco use in the United States, subgroups that report higher levels of negative affect may continue to...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.107883
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Participation in Alcoholics Anonymous (AA) and Narcotics Anonymous (NA) during and following treatment has been found to confer recovery-related benefit among adults and adolescents, but little is known about emerging adults (18-24 years). This transitional life-stage is distinctive for greater distress, hig...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2012.10.005
更新日期：2013-04-01 00:00:00
abstract：:Nicotine replacement therapies (NRT) have been available without a prescription in the United States since 1996. Given that nicotine, at least as it is delivered through tobacco products, is addictive, we examined whether NRT was being used by individuals who have never smoked cigarettes. Adults (n=18,986) and adolesc...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2008.05.001
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND:This study describes the frequency and characteristics of aggression and/or violence in ambulance attendances involving alcohol, illicit and/or pharmaceutical drug use in Victoria, Australia between January 2012 and January 2017. METHODS:Patient characteristics, context, and substance use involvement in amb...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2019.107685
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVE:Physical pain is considered a potential predictor of relapse in alcohol-dependent individuals after treatment. The aim of this study was to evaluate whether reductions in pain level during the follow-up period after treatment were associated with lower relapse risk. METHOD:A sample of 366 participants was re...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.11.020
更新日期：2016-01-01 00:00:00
abstract：:This paper aims to outline some of the caveats inherent in studies on first and second messengers in the central nervous system as related to tolerance and dependence. Analysis of systems based on measures of first and second messengers may be an over-simplification, since the actual molecular consequences of neurotra...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(79)90013-9
更新日期：1979-05-01 00:00:00
abstract：:In a study of the effect of 26 psychoactive drugs on the complex of mouse behaviour changes caused by acetaldehyde it was found that tranquillizers, hypnotics, sodium oxybutyrate and ethanol are the most efficient. The differences in teh drug effects were determined by a tan alpha criterion. Antidepressants and neurol...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(81)90103-4
更新日期：1981-09-01 00:00:00
abstract：BACKGROUND:States have attempted to reduce prescription opioid abuse through strengthening the regulation of pain management clinics; however, the effect of such measures remains unclear. We quantified the impact of Texas's September 2010 "pill mill" law on opioid prescribing and utilization. METHODS:We used the IMS H...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.12.025
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:In this study we estimate suspected links between youthful behavioral problems and smoking of tobacco, cannabis, and coca paste. METHODS:In the Republic of Chile, school-attending youths were sampled from all 13 regions of the country, with sample size of 46,907 youths from 8th to 12th grades. A Generalized...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2009.03.010
更新日期：2009-09-01 00:00:00
abstract：:The major objectives of the present study were 2-fold: (1) to demonstrate the superiority of receiver operating characteristic (ROC) methodology in the comparison of screening tests that yield continuous values; and (2) to identify the best screening indicator of current drug use disorders in alcoholics. We evaluated ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(88)90056-7
更新日期：1988-05-01 00:00:00
abstract：:The addictive and euphorogenic properties of cocaine are thought to result from inhibition of the dopamine transporter (DAT). Recent evidence suggests that dopamine and cocaine bind to distinct sites on the transporter protein. Therefore it should be possible to design drugs which specifically inhibit cocaine recognit...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(97)00102-6
更新日期：1997-10-25 00:00:00
abstract：BACKGROUND:This study evaluated plasma buprenorphine concentrations 24-72 h following sublingual administration of a dose of buprenorphine solution, ranging from 16 mg/70 kg to 44 mg/70 kg, administered on a daily or thrice-weekly schedule. Additionally, this study evaluated the effects of different thrice-weekly bupre...
journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0376-8716(98)00192-6
更新日期：1999-06-01 00:00:00
abstract：BACKGROUND:An emerging area of preclinical research has investigated whether drug use in parents prior to conception influences drug responsivity in their offspring. The present work sought to further characterize such effects with cannabis by examining whether a parental THC history modified locomotor sensitization to...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.107985
更新日期：2020-07-01 00:00:00
abstract：:Our primary aim in this study has been to evaluate selected conditions thought to influence the entry of injecting drug users (IDU) into detoxification and methadone maintenance programs, making use of a prospective study design to strengthen a cross-sectional investigation of these conditions. To begin our investigat...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(94)90095-7
更新日期：1994-10-01 00:00:00
abstract：:The purpose of the present investigation was to examine the development of tolerance to the effects of morphine and other mu opioids in rats responding under a fixed-consecutive-number (FCN) schedule of food presentation. To this end, five rats were trained under an FCN schedule and subsequently tested with a variety ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(97)00039-2
更新日期：1997-06-06 00:00:00
