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The prevalence and clinical features of amphetamine-induced obsessive compulsive disorder.

Abstract：

BACKGROUND:Amphetamine abuse is increasing worldwide, and the occurrence of amphetamine-induced (AI) psychiatric issues further complicates treatment. In response, the DSM 5 has introduced the classification of amphetamine-induced obsessive-compulsive disorders (AI-OCD), though little has been published on either its prevalence rates or its clinical features. The aim of the present study was therefore to investigate the prevalence of AI-OCD, to describe patients' clinical features, and to compare the prevalence rate among such patients with those for OCD in the general population in Western countries and Iran. METHODS:A total of 547 patients with amphetamine abuse or dependency and with a positive urine test (mean age: 31.64 years; 75.5% males) took part in the study. A psychiatric interview was carried out, covering both socio-demographic and illness-related information. RESULTS:18 (3.3%) patients suffered from OCD prior to amphetamine abuse, 491 (89.8%) had no OCD, and 38 (6.9%) suffered from AI-OCD. Neither socio-demographic nor illness-related dimensions predicted patients with diagnosed AI-OCD. The prevalence of AI-OCD was significantly higher than that for OCD in the general population (2.3% in Western countries, 1.8% in Iran). CONCLUSIONS:Data suggest that prevalence rate of AI-OCD is about 7%. Neither socio-demographic nor illness-related dimensions predicted the occurrence of AI-OCD. Thus, it remains unclear why some amphetamine abusers develop AI-OCD while others do not.

journal_name

Drug Alcohol Depend

journal_title

Drug and alcohol dependence

authors

Shakeri J,Farnia V,Karimi AR,Tatari F,Juibari TA,Alikhani M,Bajoghli H,Holsboer-Trachsler E,Brand S

doi

10.1016/j.drugalcdep.2015.12.034

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

157-62

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(16)00005-3

journal_volume

160

pub_type

杂志文章

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