Abstract：
BACKGROUND:The problematic use of prescription drugs (PDs) and related disorders are considerably prevalent but evidence concerning brief intervention for problematic PD users is sparse. A previous analysis of the present study on the effectiveness of brief intervention for problematic PD use in a general hospital revealed a significant reduction in PD use after 3 months. The analyses presented herein provides data from the 12-month follow-up. METHOD:In a randomized controlled trial, 126 proactively recruited general hospital patients were analyzed. The intervention group received two brief Motivational Interviewing (MI) sessions. Two follow-ups (after 3 and 12 months) were conducted. Intervention effects at 12-month follow-up on PD cessation and reduction were analyzed using regression methods and controlling for significant group differences. Subgroups of sedative/hypnotic- and opioid-users were examined. RESULTS:No significant intervention effects were found in the overall sample. Respecting significant differences between the intervention and control groups, we detected no effects of the intervention for the subgroups of sedative/hypnotic- or opioid-users. CONCLUSIONS:In contrast to the short-term effects after 3 months, no long-term effects of brief MI sessions on PD use were found. More intensive interventions, booster-sessions or regular aftercare might help in stabilizing intervention effects on PD use among hospital patients. However, studies using larger samples are needed to allow more powerful and specific analyses. Different samples should be examined. Problems concerning the recruitment of study participants in PD research were discussed and should be considered in further studies.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Otto C,Crackau B,Löhrmann I,Zahradnik A,Bischof G,John U,Rumpf HJdoi
10.1016/j.drugalcdep.2009.07.010subject
Has Abstractpub_date
2009-12-01 00:00:00pages
221-6issue
3eissn
0376-8716issn
1879-0046pii
S0376-8716(09)00282-8journal_volume
105pub_type
杂志文章,随机对照试验abstract：AIMS:We aimed to assess the prevalence of sleep disturbance in early alcohol recovery and its association with psychiatric comorbidity, cravings, propensity and severity of alcohol consumption. DESIGN:The sample consisted of 18-80 year old patients (n = 303) receiving treatment for alcohol dependence. Sleep disturbanc...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2019.107655
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:It is known that daily smoking is associated with the development of alcohol use disorders. However, non-daily smoking is prevalent in young adults and is associated with increased rates of problematic alcohol use in cross-sectional data. It is unknown whether non-daily smoking is predictive of hazardous dri...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2011.02.022
更新日期：2011-10-01 00:00:00
abstract：:The role of Delta(9)-tetrahydrocannabinol (THC) in driver impairment and motor vehicle crashes has traditionally been established in experimental and epidemiological studies. Experimental studies have repeatedly shown that THC impairs cognition, psychomotor function and actual driving performance in a dose related man...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,评审
doi：10.1016/j.drugalcdep.2003.10.008
更新日期：2004-02-07 00:00:00
abstract：BACKGROUND:To assess the mechanism by which a collaborative care (CC) intervention improves self-reported abstinence among primary care patients with opioid and alcohol use disorders (OAUD) compared to treatment as usual. METHODS:Secondary data analysis of SUMMIT, a randomized controlled trial of CC for OAUD. Particip...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.drugalcdep.2018.07.027
更新日期：2018-11-01 00:00:00
abstract：:The Wide Range Achievement Test (Revised) (WRAT-R) reading test, demographic variables and drug use severity were used to develop prediction equations to estimate premorbid ability in 92 cocaine abusers. WRAT-R reading was correlated significantly with full scale, verbal and performance IQ. Stepwise regression indicat...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(95)01191-9
更新日期：1995-12-01 00:00:00
abstract：BACKGROUND:Mental health diagnoses (MHD) are common among those with opioid use disorders (OUD). Methadone/buprenorphine are effective medication-assisted treatment (MAT) strategies; however, treatment receipt is low among those with dual MHDs. Medicaid expansions have broadly increased access to OUD and mental health ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.107952
更新日期：2020-04-01 00:00:00
abstract：:The addictive and euphorogenic properties of cocaine are thought to result from inhibition of the dopamine transporter (DAT). Recent evidence suggests that dopamine and cocaine bind to distinct sites on the transporter protein. Therefore it should be possible to design drugs which specifically inhibit cocaine recognit...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(97)00102-6
更新日期：1997-10-25 00:00:00
abstract：:The current study explored the judgments individuals with Substance Use Disorders (SUDs) make regarding the authenticity of enjoyment smiles and masking smiles containing traces of negative emotions. Accuracy at identifying the masked negative emotions were also examined. Eye-movements were recorded to observe relatio...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.107842
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Heart rate variability (HRV) is of interest to researchers due to its potential utility as a marker for both physiological and psychological stress. Sympatholytics are used to treat opioid withdrawal, but little information about the parasympathetic system's role in mediating withdrawal symptoms exists. The ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2019.06.040
更新日期：2019-11-01 00:00:00
abstract：:A prospective double-blind placebo-controlled trial of intramuscular Naftidrofuryl was carried out on 32 randomly selected hospitalized male alcoholic patients with clinical, biochemical and histological evidence of hepatic damage. Seventeen patients received the drug (40 mg in 5 ml i.m. three times daily for 6 days) ...
journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0376-8716(82)90004-7
更新日期：1982-10-01 00:00:00
abstract：BACKGROUND:The objective of this study was to examine depressive symptoms overtime and quantify the variance in symptoms attributable to substance use among a cohort of HIV-positive and HIV-negative men. METHODS:Participants were enrolled in an NIH/NIDA funded cohort, with 534 men resulting in 1,888 visits between Aug...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,多中心研究
doi：10.1016/j.drugalcdep.2019.107770
更新日期：2020-02-01 00:00:00
abstract：:Social context may be an important determinant of drug and alcohol consumption and HIV-related behaviors. To assess the influence of peers on drug users' risk behaviors this study examined the association between individual level and group level behaviors. This analysis reports on the prospective association between b...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(96)01279-3
更新日期：1996-11-01 00:00:00
abstract：BACKGROUND:Reduced cardio-vascular health has been found in patients suffering from alcohol dependence. Low cardio-respiratory fitness is an independent predictor of cardio-vascular disease. METHODS:We investigated physical fitness in 22 alcohol-dependent patients 10 days after acute alcohol withdrawal and compared re...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.03.016
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:State prescription monitoring programs (PMPs) purport to address the prescription opioid epidemic, but have evidenced limited effect on reducing opioid-related mortality. METHODS:We systematically reviewed publicly available, PMP web-based materials from December, 2012 to October, 2013, to assess the degree...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.05.009
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:Nicotine is commonly abused in adolescence and is believed to be a "gateway" to other drugs of abuse [e.g., methamphetamine (METH)]. The relationship between early nicotine exposure and later METH use is complicated because the majority of juvenile smokers continue to use cigarettes into adulthood. Thus, the...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2014.06.029
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Methadone maintenance treatment (MMT) is effective in decreasing opioid use or facilitating abstinence. Previous studies using small opioid use disorder samples suggest that cognitive impairments including impulsivity and executive functions may partially improve on MMT, but a range of deficits may persist. ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.108483
更新日期：2021-02-01 00:00:00
abstract：:This study examined plasma cotinine replacement levels of 56 outpatient smokers administered a 21 mg/day transdermal nicotine patch (Nicoderm CQ ). The percentage of cotinine replacement ranged from 35 to 232% (mean 107%; median 90.5%). Four subject variables were found to be significantly correlated with percentage o...
journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0376-8716(98)00163-x
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:The aims were to determine: (i) quantity and frequency of same-day use of opioids with benzodiazepines and/or alcohol amongst people who regularly tamper with pharmaceutical opioids; and (ii) socio-demographic, mental health, harms and treatment profile associated with same-day use of high doses. METHOD:The ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.07.003
更新日期：2016-09-01 00:00:00
abstract：INTRODUCTION:There is concern that recreational marijuana legalization (RML) may lead to increased cannabis use disorder (CUD) among youth due to increased marijuana use. This study investigates whether adolescent substance use disorder treatment admissions for marijuana use increased in Colorado and Washington followi...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2020.107960
更新日期：2020-05-01 00:00:00
abstract：:The information on drinking habits contained in medical records with that obtained through the CAGE alcoholism screening test was compared for 124 inpatients of a teaching general hospital. This survey was followed by testing the possibility of introducing the CAGE test into the routine clinical interview. A second an...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(85)90083-3
更新日期：1985-09-01 00:00:00
abstract：BACKGROUND:Cross-sectional studies have demonstrated gender-related differences in the associations between problem-gambling severity and substance-use disorders; however, these associations have not been examined longitudinally. We aimed to examine the prospective associations between problem-gambling severity and inc...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.05.002
更新日期：2013-11-01 00:00:00
abstract：:The present study describes an ultra-rapid opiate detoxification method using direct transition from heroin or methadone to oral naltrexone after deep sedation with oral midazolam in conjunction with ondansetron and clonidine treatment. Twenty patients were detoxified with the method. No serious events occurred, but t...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(98)00100-8
更新日期：1998-11-01 00:00:00
abstract：BACKGROUND:Agonist replacement treatment is a promising strategy to manage cannabis-use disorders. The aim of this study was to assess the combined effects of the synthetic cannabinoid agonist nabilone and Δ⁹-tetrahydrocannabinol (Δ⁹-THC) using drug-discrimination procedures, which are sensitive to drug interactions. T...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.drugalcdep.2010.11.019
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To conduct a 16-week, randomized, placebo-controlled, double-blind trial of two GABAergic medications, baclofen (20 mg tid) and gabapentin (800 mg tid), for the treatment of methamphetamine dependence. METHODS:Adults with methamphetamine dependence were randomized to one of three conditions for 16 weeks: bac...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.drugalcdep.2006.03.019
更新日期：2006-12-01 00:00:00
abstract：AIM:To examine how buprenorphine is currently being used across Italy, and to identify simultaneously best practice protocols to guide physicians in optimising the safety and efficacy of this treatment option. DESIGN:Retrospective, observational, multi-centre study. PARTICIPANTS:A total of 979 opioid-dependent patien...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,多中心研究
doi：10.1016/j.drugalcdep.2007.10.017
更新日期：2008-04-01 00:00:00
abstract：:Synaptosomal plasma membrane (SPM), like other plasma membranes, is composed of lipids and proteins and appears to conform to the "fluid mosaic" model proposed by Singer and Nicolson. SPM components show a marked asymmetry with respect to their inside-outside distribution, with the majority of proteins being external....
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(79)90064-4
更新日期：1979-01-01 00:00:00
abstract：:In order to measure changes in HIV-related behaviors among heterosexual alcoholics following treatment, we conducted a prospective cohort study of 700 self-identified alcoholics recruited from five public alcohol treatment centers, all of which included HIV risk-reduction counseling. Respondents underwent an HIV antib...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(96)01321-x
更新日期：1997-01-10 00:00:00
abstract：:In this discussion of contributed papers for the special issue of DAD, the author draws attention to early American laws concerning cannabis and to statements made about the epidemiology of cannabis smoking and other drug use between 1858 and the contemporary scene, with coverage of opium, heroin, tobacco, alcohol, co...
journal_title：Drug and alcohol dependence
pub_type： 历史文章,杂志文章
doi：10.1016/j.drugalcdep.2012.04.006
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:There is growing interest in the provision of parenting support to substance misusing parents. METHODS:This pragmatic, multi-center randomized controlled trial compared an intensive one-to-one parenting program (Parents under Pressure, PuP) with Treatment as Usual (TAU) in the UK. Parents were engaged in co...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.drugalcdep.2018.08.044
更新日期：2019-01-01 00:00:00
abstract：:Impulsivity appears to play an important role in suicidal behaviors and drug abuse, which are two psychiatric problems that may interact with one another. Interpretation of the literature on impulsivity in these behaviors may be complicated by the variety of measurement techniques for the assessment of impulsivity. Th...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2004.08.010
更新日期：2004-12-07 00:00:00
