The role of negative affect in the persistence of nicotine dependence among alternative high school students: A latent growth curve analysis.


BACKGROUND:Previous research has demonstrated how negative affect (i.e., depression, anxiety, stress) is often a correlate of and precursor to nicotine dependence. Although recent evidence shows a gradual decline in tobacco use in the United States, subgroups that report higher levels of negative affect may continue to be at risk of becoming dependent on nicotine. One high-risk subgroup is students who attend alternative high schools. The current longitudinal investigation examined the effect of negative affect on nicotine dependence in this youth population. METHODS:1060 students from 29 alternative high schools in Southern California completed a series of attitudinal and behavioral measures once per year over a three-year period. The main outcome was nicotine dependence i.e., feeling a strong urge to use nicotine products or experiencing withdrawal symptoms after a period of abstinence, measured using a version of the Fagerstrom Tolerance Questionnaire designed for adolescents. A latent growth curve model was utilized to examine the effect of negative affect on nicotine dependence during this timeframe. RESULTS:The analysis revealed that negative affect had both a concurrent and prospective relationship with nicotine dependence. Moreover, the association between negative affect and nicotine dependence in the present was not statistically significant once the influence of negative affect reported one year earlier was accounted for. CONCLUSIONS:Negative affect may play a critical role in the persistence of nicotine dependence among high-risk youth. Providing resources to help manage negative affect may be critical to curtailing nicotine dependence in this population.


Drug Alcohol Depend


Miller S,Pike J,Shono Y,Beleva Y,Xie B,Stacy AW




Has Abstract


2020-04-01 00:00:00












  • Impaired time perception and motor timing in stimulant-dependent subjects.

    abstract::Stimulant-dependent individuals (SDI) have abnormal brain metabolism and structural changes involving dopaminergic target areas important for the processing of time. These individuals are also more impulsive and impaired in working memory and attention. The current study tested whether SDI show altered temporal proces...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Wittmann M,Leland DS,Churan J,Paulus MP

    更新日期:2007-10-08 00:00:00

  • Environmental enrichment as a potential intervention for heroin seeking.

    abstract:BACKGROUND:Heroin-related cues can trigger craving and relapse in addicts or heroin seeking in rats. In the present study we investigated whether environmental enrichment (EE) implemented after heroin exposure can reduce cue-induced reinstatement of heroin seeking and expression of heroin conditioned place preference. ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Galaj E,Manuszak M,Ranaldi R

    更新日期:2016-06-01 00:00:00

  • Gestational buprenorphine exposure: Effects on pregnancy, development, neonatal opioid withdrawal syndrome, and behavior in a translational rodent model.

    abstract:BACKGROUND:The opioid crisis has led to an increased number of pregnant opioid-dependent women receiving opioid-maintenance therapy (e.g. buprenorphine, BUP), but little is known about the consequences of gestational BUP exposure on pregnancy outcomes, maternal care, or offspring development. METHODS:Our translational...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Wallin CM,Bowen SE,Roberge CL,Richardson LM,Brummelte S

    更新日期:2019-12-01 00:00:00

  • Healthcare professionals' regard towards working with patients with substance use disorders: comparison of primary care, general psychiatry and specialist addiction services.

    abstract:BACKGROUND:Healthcare professionals are crucial in access to treatment for patients with substance use disorders. However, healthcare professionals often have negative attitudes towards this patient group. Healthcare professionals' regard for working with patients with substance use disorders was examined and three sec...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验


    authors: van Boekel LC,Brouwers EPM,van Weeghel J,Garretsen HFL

    更新日期:2014-01-01 00:00:00

  • Evaluation of the rewarding effects of mitragynine and 7-hydroxymitragynine in an intracranial self-stimulation procedure in male and female rats.

    abstract:BACKGROUND:Kratom (Mitragyna speciosa Korth.) has been used in Southeast Asia for hundreds of years to increase energy, for relaxation, and to diminish opioid withdrawal. Kratom use has recently spread to Western countries. Kratom could potentially be used for the treatment of opioid withdrawal and pain, but more insig...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Behnood-Rod A,Chellian R,Wilson R,Hiranita T,Sharma A,Leon F,McCurdy CR,McMahon LR,Bruijnzeel AW

    更新日期:2020-10-01 00:00:00

  • Factors associated with history of non-fatal overdose among young nonmedical users of prescription drugs.

    abstract:OBJECTIVES:The current study examines the prevalence and correlates of lifetime non-fatal overdose (OD) involving the nonmedical use of prescription opioids and tranquilizers among a sample of high-risk young adults in New York, NY and Los Angeles, CA. METHODS:Data were derived from a cross-sectional study of 16-25 ye...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Silva K,Schrager SM,Kecojevic A,Lankenau SE

    更新日期:2013-02-01 00:00:00

  • The influence of monetary punishment on cognitive control in abstinent cocaine-users.

    abstract:BACKGROUND:Dependent drug users show a diminished neural response to punishment, in both limbic and cortical regions, though it remains unclear how such changes influence cognitive processes critical to addiction. To assess this relationship, we examined the influence of monetary punishment on inhibitory control and ad...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Hester R,Bell RP,Foxe JJ,Garavan H

    更新日期:2013-11-01 00:00:00

  • Cannabis dependence, withdrawal, and reinforcing effects among adolescents with conduct symptoms and substance use disorders.

    abstract::The prevalence of cannabis use is rising among adolescents, many of whom perceive little risk from cannabis. However, clinicians who treat adolescent substance users hear frequent reports of serious cannabis-use disorders and problems. This study asked whether cannabis produced dependence and withdrawal among such pat...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Crowley TJ,Macdonald MJ,Whitmore EA,Mikulich SK

    更新日期:1998-03-01 00:00:00

  • The cost of treating addiction from the client's perspective: results from a multi-modality application of the Client DATCAP.

    abstract::There is a considerable disparity between the number of individuals who need substance abuse treatment and the number who actually receive it. This is partly due to the fact that many individuals with substance use disorders do not perceive a need for formal treatment. Another contributing factor, however, is a discre...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: McCollister KE,French MT,Pyne JM,Booth B,Rapp R,Carr C

    更新日期:2009-10-01 00:00:00

  • Associations between pain intensity and urge to smoke: Testing the role of negative affect and pain catastrophizing.

    abstract:BACKGROUND:Cigarette smokers are more likely to experience pain than nonsmokers, and experimental research indicates that pain is a potent motivator of smoking. Urge to smoke is a predictor of early relapse, yet associations between pain and urge to smoke have yet to be tested among daily smokers. This study aimed to c...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Kosiba JD,Zale EL,Ditre JW

    更新日期:2018-06-01 00:00:00

  • Outcomes after methadone maintenance and methadone reduction treatments: two-year follow-up results from the National Treatment Outcome Research Study.

    abstract::This paper provides a detailed analysis of the 2-year outcomes for 351 drug misusers allocated on an intention-to-treat basis to methadone maintenance or methadone reduction treatments. Both groups showed substantial reductions in their use of illicit drugs and in other outcome areas. However, whereas most methadone m...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Gossop M,Marsden J,Stewart D,Treacy S

    更新日期:2001-05-01 00:00:00

  • Racial and gender inequities in the implementation of a cannabis criminal justice diversion program in a large and diverse metropolitan county of the USA.

    abstract:BACKGROUND:Diversion programs are considered alternatives to the arrest and incarceration of non-violent drug offenders, including those found in possession of smaller amounts of cannabis in states with prohibitive laws. Despite the progressive nature of such programs, the inability to complete diversion program requir...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Sanchez HF,Orr MF,Wang A,Cano MÁ,Vaughan EL,Harvey LM,Essa S,Torbati A,Clark US,Fagundes CP,de Dios MA

    更新日期:2020-11-01 00:00:00

  • DRD2 genotypes and substance use in adolescent children of alcoholics.

    abstract::Research has identified children of alcoholics (COAs) as a population at increased risk for developing substance use problems. Genetic studies support the Al allele of the D2 dopamine receptor gene (DRD2) as a risk marker for alcoholism and substance use disorders. In this study, substance use was assessed in 48 adole...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Conner BT,Noble EP,Berman SM,Ozkaragoz T,Ritchie T,Antolin T,Sheen C

    更新日期:2005-09-01 00:00:00

  • Evaluation of TSPO PET imaging, a marker of glial activation, to study the neuroimmune footprints of morphine exposure and withdrawal.

    abstract:INTRODUCTION:A growing area of research suggests that neuroimmunity may impact the pharmacology of opioids. Microglia is a key component of the brain immunity. Preclinical and clinical studies have demonstrated that microglial modulators may improve morphine-induced analgesia and prevent the development of tolerance an...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Auvity S,Goutal S,Thézé B,Chaves C,Hosten B,Kuhnast B,Saba W,Boisgard R,Buvat I,Cisternino S,Tournier N

    更新日期:2017-01-01 00:00:00

  • Trends in engagement in the cascade of care for opioid use disorder, Vancouver, Canada, 2006-2016.

    abstract:BACKGROUND:A cascade of care framework has been proposed to identify and address implementation gaps in addiction medicine. Using this framework, we characterized temporal trends in engagement in care for opioid use disorder (OUD) in Vancouver, Canada. METHODS:Using data from two cohorts of people who use drugs, we as...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Socías ME,Wood E,Kerr T,Nolan S,Hayashi K,Nosova E,Montaner J,Milloy MJ

    更新日期:2018-08-01 00:00:00

  • Alcohol high risk drinking, abuse and dependence among tobacco smoking medical care patients and the general population.

    abstract:BACKGROUND:Little is known about the synergies of smoking and alcohol consumption in medical care patients. The objective, therefore, is to estimate the coincidence of hazardous and harmful alcohol consumption as well as alcohol abuse and dependence with tobacco smoking in a general hospital and general practices. MET...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: John U,Hill A,Rumpf HJ,Hapke U,Meyer C

    更新日期:2003-03-01 00:00:00

  • Changes in dopamine receptor responsivity during alcohol detoxification may predict relapse.

    abstract::In the search for clinical and biological variables that may predict relapse of alcohol dependent patients after detoxification, we followed up for 1 year male patients that had undergone successful detoxification. The patients had been tested earlier during their usual alcohol consumption and immediately after detoxi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Markianos M,Lykouras L,Moussas G,Hatzimanolis J

    更新日期:2001-11-01 00:00:00

  • Transdermal nicotine alters some of marihuana's effects in male and female volunteers.

    abstract::Despite the fact that tobacco and marihuana are often used together, relatively little is known about the effects of this combination. In order to investigate the effects of the principal psychoactive component in tobacco smoke, nicotine, on marihuana-induced intoxication, we conducted a double blind, cross-over exper...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验


    authors: Penetar DM,Kouri EM,Gross MM,McCarthy EM,Rhee CK,Peters EN,Lukas SE

    更新日期:2005-08-01 00:00:00

  • Zipeprol is a newly abused antitussive with an opioid spectrum and hallucinogenic effects.

    abstract::Zipeprol is a non-opioid cough suppressor agent recently abused in Italy. Clinical reports from 30 street abusers show that the drug in high doses has a definite abuse liability and dependence potential. Many of its effects were identical to those induced by opiates, although specific dysperceptive symptoms were commo...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Janiri L,Mannelli P,Persico AM,Diodato S,Tempesta E

    更新日期:1991-03-01 00:00:00

  • Understanding US addiction physicians' low rate of naltrexone prescription.

    abstract::Naltrexone was approved by the US Food and Drug Administration (FDA) in December 1994. Although it is one of only two medications for alcohol rehabilitation approved in the US, naltrexone is not frequently prescribed. This paper examines the factors limiting physicians' use of naltrexone. Data were collected through a...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Mark TL,Kranzler HR,Song X

    更新日期:2003-09-10 00:00:00

  • The role of subjective responses in electronic cigarette uptake and substitution in adult smokers.

    abstract:BACKGROUND:While a majority of cigarette smokers who use electronic cigarettes (e-cigarettes) choose to continue using cigarettes, completely switching to e-cigarettes is necessary to reduce tobacco-related harm. Whether specific subjective responses to e-cigarettes are associated with extent of smoking reduction and c...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Gades MS,Petersen A,Meier E,Lindgren BR,O'Connor RJ,Shields PG,Hatsukami D

    更新日期:2020-07-01 00:00:00

  • Changes over time in young adults' harmful alcohol consumption: A cross-temporal meta-analysis using the AUDIT.

    abstract:BACKGROUND:Recent studies suggest that young adult participation in, and volume of, alcohol consumption has decreased. However, the evidence on trends in harmful alcohol consumption in this age group is limited. The current paper aims to examine changes over time in harmful alcohol consumption using a robust, widely em...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Visontay R,Mewton L,Sunderland M,Prior K,Slade T

    更新日期:2020-09-01 00:00:00

  • Buprenorphine in primary care: risk factors for treatment injection and implications for clinical management.

    abstract:AIMS:Though the introduction of office-based buprenorphine has greatly contributed to stem the HIV epidemic since 1995, concerns have been raised about the intravenous use of buprenorphine even in patients on substitution treatment. The aim of this study was to identify which factors are predictive of buprenorphine inj...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Roux P,Villes V,Blanche J,Bry D,Spire B,Feroni I,Carrieri MP

    更新日期:2008-09-01 00:00:00

  • Regional differences in high-affinity choline uptake in brain after acute and chronic treatment with ethanol.

    abstract::A single dose of ethanol has been shown to affect both striatal and hippocampal high-affinity choline uptake. This effect is probably mediated through effects of ethanol on acetylcholine release. Choline uptake has also been shown to be altered in ethanol-dependent animals, and these effects may be coupled to alterat...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Hunt WA,Majchrowicz E

    更新日期:1979-05-01 00:00:00

  • Tolerance and cross tolerance to the accuracy- and rate-decreasing effects of mu opioids in rats responding under a fixed-consecutive-number schedule.

    abstract::The purpose of the present investigation was to examine the development of tolerance to the effects of morphine and other mu opioids in rats responding under a fixed-consecutive-number (FCN) schedule of food presentation. To this end, five rats were trained under an FCN schedule and subsequently tested with a variety ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Smith MA,Pitts RC,Picker MJ

    更新日期:1997-06-06 00:00:00

  • Patterns and correlates of attempted suicide by heroin users over a 3-year period: findings from the Australian treatment outcome study.

    abstract::In order to determine patterns and correlates of attempted suicide amongst heroin users across 3 years, a cohort of 387 heroin users (134 entering maintenance treatment, 134 entering detoxification, 81 entering residential rehabilitation and 38 not entering treatment) were interviewed about suicide attempts at baselin...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,多中心研究


    authors: Darke S,Ross J,Williamson A,Mills KL,Havard A,Teesson M

    更新日期:2007-03-16 00:00:00

  • Dronabinol and lofexidine for cannabis use disorder: A randomized, double-blind, placebo-controlled trial.

    abstract:BACKGROUND:Cannabis use disorder is associated with substantial morbidity and, after alcohol, is the most common drug bringing adolescents and adults into treatment. At present, there are no FDA-approved medications for cannabis use disorder. Combined pharmacologic interventions might be particularly useful in mitigati...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验


    authors: Levin FR,Mariani JJ,Pavlicova M,Brooks D,Glass A,Mahony A,Nunes EV,Bisaga A,Dakwar E,Carpenter KM,Sullivan MA,Choi JC

    更新日期:2016-02-01 00:00:00

  • Screening for current drug use disorders in alcoholics: an application of receiver operating characteristic analysis.

    abstract::The major objectives of the present study were 2-fold: (1) to demonstrate the superiority of receiver operating characteristic (ROC) methodology in the comparison of screening tests that yield continuous values; and (2) to identify the best screening indicator of current drug use disorders in alcoholics. We evaluated ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Grant BF,Hasin DS,Harford TC

    更新日期:1988-05-01 00:00:00

  • Neurochemical similarities between d,l-cathinone and d-amphetamine.

    abstract::Cathinone, the principal alkaloid of Khat, was compared to the psychomotor stimulant d-amphetamine on a number of neurochemical measures. Like d-amphetamine, d,l-cathinone released and blocked the uptake of tritiated dopamine (DA) in synaptosomal preparations. In addition, repeated high doses of d,l-cathinone produced...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Wagner GC,Preston K,Ricaurte GA,Schuster CR,Seiden LS

    更新日期:1982-08-01 00:00:00

  • Sponsorship and service as mediators of the effects of Making Alcoholics Anonymous Easier (MAAEZ), a 12-step facilitation intervention.

    abstract::A recent trial (n=508) of "Making Alcoholics Anonymous Easier" (MAAEZ), a group-format 12-step facilitation program, showed that MAAEZ participants had increased odds of abstinence (OR=1.58; p=0.063). Effects were especially marked in several subgroups, including those with more prior AA/NA/CA exposure, and those with...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Subbaraman MS,Kaskutas LA,Zemore S

    更新日期:2011-07-01 00:00:00