Lesions produced by Clostridium butyricum strain CB 1002 in ligated intestinal loops in guinea pigs.

Abstract:

:Heated spores (80 degrees C, 10 min) of Clostridium butyricum strain CB 1002 isolated from a fatal case of necrotising enterocolitis in a human neonate were inoculated into ligated intestinal loops prepared in young conventional guinea pigs. Necropsy findings 18 h later included congestion, patchy haemorrhage of the intestinal mucosa and bacteraemia. No abnormalities were observed in control loops given inocula of inactivated spores (heated at 100 degrees C for 10 min) or TYG 6 medium. The results suggest that vascular lesions are produced by C. butyricum in the intestine of young conventional guinea pigs.

journal_name

J Med Microbiol

authors

Popoff MR,Ravisse P

doi

10.1099/00222615-19-3-351

subject

Has Abstract

pub_date

1985-06-01 00:00:00

pages

351-7

issue

3

eissn

0022-2615

issn

1473-5644

journal_volume

19

pub_type

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