A small-molecule compound belonging to a class of 2,4-disubstituted 1,3,4-thiadiazine-5-ones inhibits intracellular growth and persistence of Chlamydia trachomatis.

abstract：:Xanthomonas maltophilia produces two inducible beta-lactamases, L1 and L2, and resists the antimicrobial activity of beta-lactam antibiotics, including carbapenems. L1 is a zinc-metaloenzyme with carbapenemase activity; L2 is an unusual cephalosporinase. Mutant strains with high- and low-level constitutive expression ...

journal_title：Journal of medical microbiology

authors： Akova M,Bonfiglio G,Livermore DM

更新日期：1991-10-01 00:00:00

abstract：:Candida parapsilosis is the second most frequent Candida species isolated from blood cultures. Since 2005, C. parapsilosis has been divided into three distinct species based on genetic traits: Candida parapsilosis, Candida metapsilosis and Candida orthopsilosis. The aim of this study was to develop a rapid real-time P...

journal_title：Journal of medical microbiology

authors： Hays C,Duhamel C,Cattoir V,Bonhomme J

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:The aim of this work was to evaluate and optimize the identification of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica (usually known as the classical Bordetella species) using Bruker Biotyper matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF M...

journal_title：Journal of medical microbiology

authors： Zintgraff J,Irazu L,Lara CS,Rodriguez M,Santos M

更新日期：2018-12-01 00:00:00

abstract：:The genetic diversity between major meticillin-resistant Staphylococcus aureus (MRSA) lineages was probed using fluorescent amplified fragment length polymorphism (FAFLP) as a random genome sampling tool. Genomic DNA was digested with endonucleases BglII and Csp6I and a subset of the restricted fragments were amplifie...

journal_title：Journal of medical microbiology

authors： Desai D,Ellington MJ,Arnold C,Desai M

更新日期：2012-12-01 00:00:00

abstract：:A periplasmic flagellin gene, flaB, of Leptospira interrogans serovar pomona (strain Pomona) was expressed in Escherichia coli for the production and antigenic characterisation of the protein. The flaB structural gene, which was previously cloned into pUC118, was derived by PCR from the recombinant plasmid and used to...

journal_title：Journal of medical microbiology

authors： Lin M,Bughio N,Surujballi O

更新日期：1999-11-01 00:00:00

abstract：:Most hospital bacteriologists have divided staphylococci into two groups: Staphylococcus aureus and the coagulase-negative staphylococci of which the novobiocin-resistant varieties are termed S. saprophyticus. The identification of S. aureus has been easy but that of the other staphylococci has provided some difficult...

journal_title：Journal of medical microbiology

authors： Reuther JW

更新日期：1986-09-01 00:00:00

abstract：:Mucosal immunity in the gastrointestinal (GI) tract is a primary defence against GI pathogens. We hypothesise that a mucosal response to lipopolysaccharide (LPS), especially to the common (core) determinants of GI pathogenic Escherichia coli strains, is protective. The aims of this study were to investigate the specif...

journal_title：Journal of medical microbiology

authors： Currie CG,McCALLUM K,Poxton IR

更新日期：2001-04-01 00:00:00

abstract：:Epidemic methicillin-resistant Staphylococcus aureus types 15 and 16 (EMRSA-15 and EMRSA-16) are the dominant types of MRSA found in UK hospitals, but accurate designation of strains has been difficult. Restriction fragment length polymorphism (RFLP) profiles of seven core virulence genes were used to classify unambig...

journal_title：Journal of medical microbiology

authors： Moore PCL,Lindsay JA

更新日期：2002-06-01 00:00:00

abstract：:Competition, competitive exclusion and displacement of eight strains of Escherichia coli and Salmonella spp. by Lactobacillus rhamnosus GG and Lactobacillus casei Shirota from adhesion on human intestinal mucus glycoproteins and Caco-2 cell surfaces were studied. Lactobacilli were able to compete with, exclude and dis...

journal_title：Journal of medical microbiology

authors： Lee YK,Puong KY,Ouwehand AC,Salminen S

更新日期：2003-10-01 00:00:00

abstract：:Serology remains the mainstay for diagnosis of Epstein-Barr virus (EBV) infection. This study compared two automated platforms (BioPlex 2200 and Architect i2000SR) to test three EBV serological markers: viral capsid antigen (VCA) immunoglobulins of class M (IgM), VCA immunoglobulins of class G (IgG) and EBV nuclear an...

journal_title：Journal of medical microbiology

authors： Al Sidairi H,Binkhamis K,Jackson C,Roberts C,Heinstein C,MacDonald J,Needle R,Hatchette TF,LeBlanc JJ

更新日期：2017-11-01 00:00:00

abstract：:Leclercia adecarboxylata is a rarely reported human pathogen, most commonly affecting immunocompromised individuals. In reported cases of immunocompetent patients infected with this organism, it is seen exclusively in the context of polymicrobial infections. We report here the case of an abscess in an immunocompetent ...

journal_title：Journal of medical microbiology

authors： Hess B,Burchett A,Huntington MK

更新日期：2008-07-01 00:00:00

abstract：:Introduction. Infections with the respiratory pathogen Mycoplasma pneumoniae are often chronic, recurrent and resistant, persisting after antibiotic treatment. M. pneumoniae grown on glass forms protective biofilms, consistent with a role for biofilms in persistence. These biofilms consist of towers of bacteria inters...

journal_title：Journal of medical microbiology

authors： Feng M,Burgess AC,Cuellar RR,Schwab NR,Balish MF

更新日期：2021-01-01 00:00:00

abstract：:Aspiration of oropharyngeal bacteria and fungi is occasionally suspected in patients with pneumonia. A patient with oral carcinoma underwent chemoradioimmunotherapy and, about 4 weeks from the start of the therapy, the patient suffered from severe oral mucositis induced by chemoradiotherapy, and candidal pneumonia was...

journal_title：Journal of medical microbiology

authors： Yamamoto T,Ueta E,Kamatani T,Osaki T

更新日期：2005-05-01 00:00:00

abstract：:Production of a meningococcal vaccine capable of generating long-lasting immunity in all age groups is still a high priority worldwide. Iron-regulated outer-membrane proteins have attracted considerable attention in recent years and it has become increasingly evident that the meningococcal transferrin-binding proteins...

journal_title：Journal of medical microbiology

authors： Ala'Aldeen DA

更新日期：1996-04-01 00:00:00

abstract：:The performance of the Fungitell assay was investigated in 100 patients with haematological malignancy undergoing chemotherapy who developed antibiotic-unresponsive neutropenic fever (AUNF). Serum beta-D-glucan (BG) concentrations were significantly elevated on the first day of AUNF and all subsequent alternate days t...

journal_title：Journal of medical microbiology

authors： Ellis M,Al-Ramadi B,Finkelman M,Hedstrom U,Kristensen J,Ali-Zadeh H,Klingspor L

更新日期：2008-03-01 00:00:00

abstract：:5-Fluorouracil (5-FU), a commonly used chemotherapeutic agent, often causes oral mucositis, an inflammation and ulceration of the oral mucosa. Micro-organisms in the oral cavity are thought to play an important role in the aggravation and severity of mucositis, but the mechanisms behind this remain unclear. Although 5...

journal_title：Journal of medical microbiology

authors： Vanlancker E,Vanhoecke B,Smet R,Props R,Van de Wiele T

更新日期：2016-08-01 00:00:00

abstract：:A novel spirochaete was isolated from a case of severe virulent ovine foot rot (SVOFR) by immunomagnetic separation with beads coated with polyclonal anti-treponemal antisera and prolonged anaerobic broth culture. The as yet unnamed treponeme differs considerably from the only other spirochaete isolated from ovine foo...

journal_title：Journal of medical microbiology

authors： Demirkan I,Carter SD,Winstanley C,Bruce KD,McNAIR NM,Woodside M,Hart CA

更新日期：2001-12-01 00:00:00

abstract：:Iron is an important nutritional requirement for bacteria due to its conserved role in many essential metabolic processes. As a consequence of the lack of freely available iron in the mammalian host, bacteria upregulate a range of virulence factors during infection. Transcriptional analysis of Francisella tularensis s...

journal_title：Journal of medical microbiology

authors： Milne TS,Michell SL,Diaper H,Wikström P,Svensson K,Oyston PCF,Titball RW

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:With an increase in the numbers of bacterial isolates resistant to first-line antibiotics, there has been a revival in the use of older drugs including fosfomycin with novel mechanisms of action. We aimed to investigate the prevalence and genotypic nature of fosfomycin resistance in Escherichia coli from urinar...

journal_title：Journal of medical microbiology

authors： Cottell JL,Webber MA

更新日期：2019-02-01 00:00:00

abstract：:Transfer of an Hly plasmid determining production of alpha haemolysin to a non-haemolytic strain of Escherichia coli increased the virulence of the strain for mice. Injections of non-toxic amounts of alpha haemolysin, phenylhydrazine, haemoglobin, iron or manganese salts simulated the effect of the Hly plasmid by stim...

journal_title：Journal of medical microbiology

authors： Linggood MA,Ingram PL

更新日期：1982-02-01 00:00:00

abstract：:The increasing incidence of reported scabies in Trinidad, from 24.2/100,000 population in 1984 to 59.5/100,000 in 1985, led to a careful monitoring in 1986 of all patients with post-streptococcal acute glomerulonephritis (PSAGN). There were 181 cases of PSAGN; 84 beta-haemolytic streptococcal isolates from 72 patients...

journal_title：Journal of medical microbiology

authors： Reid HF,Bassett DC,Gaworzewska E,Colman G,Poon-King T

更新日期：1990-06-01 00:00:00

abstract：:The microbiota of the human oropharynx plays an important role in health through involvement in the aetiology of infection and the carriage of adventitious pathogens. Despite this, there are few models available for the preclinical assessment of novel antimicrobials directed to the human throat. We have profiled bacte...

journal_title：Journal of medical microbiology

authors： Humphreys GJ,McBain AJ

更新日期：2013-06-01 00:00:00

abstract：:Pseudomonas aeruginosa is an opportunistic pathogen that poses a threat in clinical settings due to its intrinsic and acquired resistance to a wide spectrum of antibiotics. Additionally, the presence of a subpopulation of cells surviving high concentrations of antibiotics, called persisters, makes it virtually impossi...

journal_title：Journal of medical microbiology

authors： De Groote VN,Fauvart M,Kint CI,Verstraeten N,Jans A,Cornelis P,Michiels J

更新日期：2011-03-01 00:00:00

abstract：:Micro-organisms isolated from the oral cavity may translocate to the lower airways during mechanical ventilation (MV) leading to ventilator-associated pneumonia (VAP). Changes within the dental plaque microbiome during MV have been documented previously, primarily using culture-based techniques. The aim of this study ...

journal_title：Journal of medical microbiology

authors： Sands KM,Twigg JA,Lewis MAO,Wise MP,Marchesi JR,Smith A,Wilson MJ,Williams DW

更新日期：2016-02-01 00:00:00

abstract：:The opsonic requirements of Helicobacter pylori were investigated in a series of experiments with human polymorphonuclear leucocytes (PMNL). Pre-incubation of H. pylori with pooled normal human serum (NHS) in concentrations of 5-20% significantly increased the uptake of radiolabelled bacteria by PMNL. Treatment of the...

journal_title：Journal of medical microbiology

authors： McKinlay AW,Young A,Russell RI,Gemmell CG

更新日期：1993-03-01 00:00:00

abstract：:Production of beta-lactamase by 15 strains of Haemophilus influenzae has been investigated. All the strains produce a constitutive beta-lactamase, which readily hydrolyses penicillin G, ampicillin, and cephaloridine. The beta-lactamase produced by these strains is indistinguishable from the type-IIIa enzyme commonly f...

journal_title：Journal of medical microbiology

authors： Sykes RB,Matthew M,O'Callaghan CH

更新日期：1975-08-01 00:00:00

abstract：:Cholera, caused by Vibrio cholerae, results in significant morbidity and mortality worldwide, including Thailand. Representative V. cholerae strains associated with endemic cholera (n = 32), including strains (n = 3) from surface water sources, in Khon Kaen, Thailand (2003-2011), were subjected to microbiological, mol...

journal_title：Journal of medical microbiology

authors： Chomvarin C,Johura FT,Mannan SB,Jumroenjit W,Kanoktippornchai B,Tangkanakul W,Tantisuwichwong N,Huttayananont S,Watanabe H,Hasan NA,Huq A,Cravioto A,Colwell RR,Alam M

更新日期：2013-04-01 00:00:00

abstract：:The susceptibility of chicks to enteritis caused by Campylobacter jejuni was studied. Three-day-old chicks did not develop enteritis after oral infection but chicks infected within 12 h of hatching developed gastroenteritis. The incubation period correlated with the inoculum size. Initially, infected chicks developed ...

journal_title：Journal of medical microbiology

authors： Welkos SL

更新日期：1984-10-01 00:00:00

abstract：PURPOSE:Staphylococcus epidermidis colonies often display several morphologies and antimicrobial susceptibility patterns when cultured from device-related infections, and may represent one or multiple genotypes. Genotyping may be helpful in the clinical interpretation, but is time consuming and expensive. We wanted to ...

journal_title：Journal of medical microbiology

authors： Larssen KW,Nor A,Bergh K

更新日期：2018-02-01 00:00:00

abstract：:Helicobacter trogontum is a micro-aerophilic urease-positive bacterium that has recently been isolated from the intestinal mucosa of rats. The purpose of this investigation was to study the ultrastructural details of this micro-organism in both pure culture and in the gastrointestinal tract of germ-free mice infected ...

journal_title：Journal of medical microbiology

authors： Moura SB,Mendes EN,Queiroz DM,Camargos ER,Evangelina M,Fonseca F,Rocha GA,Nicoli JR

更新日期：1998-06-01 00:00:00