A hypothesis on the role of pheromones on age of menarche.

abstract：:Preliminary reports have demonstrated that anterior nucleus thalamus high-frequency electrical stimulation (ANT-HFS) is an effective treatment for patients who suffer from medically refractory epilepsy. However, its extensive application has been hampered by the high cost and the unpredictable outcome before the opera...

journal_title：Medical hypotheses

authors： Yan N,Chen N,Lu J,Wang Y,Wang W

更新日期：2013-09-01 00:00:00

abstract：:(1) Background: RNA viruses and especially coronaviruses could act inside host cells not only by building their own proteins, but also by perturbing the cell metabolism. We show the possibility of miRNA-like inhibitions by the SARS-CoV-2 concerning for example the hemoglobin and type I interferons syntheses, hence hig...

journal_title：Medical hypotheses

authors： Demongeot J,Seligmann H

更新日期：2020-11-01 00:00:00

abstract：:In a previous paper we predicted that health effects of dietary fats in humans would require half a century or more to be understood, instead of the decade or so predicted during 1956 by an Editorial in The Lancet. It would seem that our prediction may have been optimistic since it has now been reported that trans uns...

journal_title：Medical hypotheses

authors： Booyens J,van der Merwe CF

更新日期：1992-04-01 00:00:00

abstract：:Intestinal dysbiosis refers to an imbalance in the intestinal flora. The concept of small intestinal bacterial overgrowth (SIBO), a condition of abnormal proliferation of the small intestine microbiota, has been proposed as a form of small intestine dysbiosis. In Parkinson's disease patients, weight loss and metabolic...

journal_title：Medical hypotheses

authors： Hasuike Y,Endo T,Koroyasu M,Matsui M,Mori C,Yamadera M,Fujimura H,Sakoda S

更新日期：2020-01-01 00:00:00

abstract：:It has been suggested that dopamine may play an important role in human evolution and adaptive behaviors. Recent studies have revealed an association between the dopamine system and social support among healthy individuals. However, the underlying mechanism remains unclear. In the present study, we propose a dopamine ...

journal_title：Medical hypotheses

authors： Lin SH,Chen PS,Yeh TL,Yang YK

更新日期：2011-11-01 00:00:00

abstract：:Ultrasound (US) is gaining recognition as a useful tool for assessing lung physiology and pathology. Yet, currently the skill of performing lung US is taught by experienced operators to novice ones, mainly by recognizing expected patterns. Recognizing the latter may be difficult and subjective. In this hypothesis we p...

journal_title：Medical hypotheses

authors： Dori G,Jakobson DJ

更新日期：2016-06-01 00:00:00

abstract：:Cytokines and their effects are widely studied in immunology, but the cellular mechanisms responsible for producing these substances are not yet described or proven. Antigen presenting cells (APCs), macrophages and dendritic cells are suitable subjects for such a study. One of the many papers illustrating the interpla...

journal_title：Medical hypotheses

authors： Fedorko ME

更新日期：1999-08-01 00:00:00

abstract：:There is growing dissatisfaction regarding the available diagnostic systems for psychiatric disorders (DSM, ICD). Psychiatrists acknowledge that though mental disease reflects brain disorders, the descriptive and symptom based nature of psychiatric diagnosis bears no relation to brain functions. According to Helmut's ...

journal_title：Medical hypotheses

authors： Peled A

更新日期：2004-01-01 00:00:00

abstract：:Papers from a generation ago suggested that phenothiazines--in particular trifluorperazine (Stelazine) a medicinal approved by the FDA and still commonly used for schizophrenia--downregulate the epidermal growth factor receptor. As numerous cancers--e.g., colon cancer, breast cancer, pancreatic cancer and glioblastoma...

journal_title：Medical hypotheses

authors： Kast RE,Altschuler EL

更新日期：2007-01-01 00:00:00

abstract：:The paper discusses a mechanism for reciprocal translocation of midsegments between two chromatids so that one of the segments is restacked in inverted configuration. Regarding malignant cells, such process could derive from anachronistic assembly of the nuclear envelope. ...

journal_title：Medical hypotheses

authors： Matioli GT

更新日期：1998-06-01 00:00:00

abstract：:NETosis, being an alternative form of cell death is the creation of web-like chromatin decondensates by suitably primed neutrophils as a response to stimulus aimed at containing and eliminating the same. In certain situations, it causes more harm than benefit in the form of bystander damage directly or via activation ...

journal_title：Medical hypotheses

authors： Gupta S,Sahni V

更新日期：2020-11-01 00:00:00

abstract：:A nutraceutical that has exploded onto the prescription pad in recent years is the fat soluble vitamin, vitamin D. This is due to an increasing medical interest in the utility of the vitamin in the treatment and prevention of an array of diseases and ailments. Despite the continued debate over the correct dose, form a...

journal_title：Medical hypotheses

authors： Braithwaite MC,Kumar P,Tyagi C,Tomar LK,Choonara YE,Pillay V

更新日期：2013-10-01 00:00:00

abstract：:Abnormal fluctuations of acetylcholine and serotonin might cause, or be correlated with, a variety of symptoms. This communication cites evidence which suggests that fluctuations of serotonin might have a causative role in migraine, mania, and depression and that fluctuations of acetylcholine might have a causative ro...

journal_title：Medical hypotheses

authors： Brown DW

更新日期：1993-05-01 00:00:00

abstract：:Fibromyalgia (FM) is a debilitating, widespread pain disorder that is assumed to originate from inappropriate pain processing in the central nervous system. Psychological and behavioral factors are both believed to underlie the pathogenesis and complicate the treatment. This hypothesis, however, has not yet been suffi...

journal_title：Medical hypotheses

authors： Hulens M,Dankaerts W,Stalmans I,Somers A,Vansant G,Rasschaert R,Bruyninckx F

更新日期：2018-01-01 00:00:00

abstract：:Numerous studies implicate cellular immunological effector systems in the partial containment of virus replication during the early stages of HIV infection. Immunostimulatory therapeutic regimes designed to enhance virus clearance are therefore theoretically attractive, but are accompanied by the risk of concomitant a...

journal_title：Medical hypotheses

authors： Wrightham MN,Cann AJ,Sewell HF

更新日期：1992-07-01 00:00:00

abstract：:A steady fall in mortality rates from cardiovascular diseases (CVD) has been reported recently in the United States. This study tests the hypothesis that fruits and vegetables had a protective effect against cardiovascular mortality among the American population from 1964-78. Special attention was focused on more spec...

journal_title：Medical hypotheses

authors： Verlangieri AJ,Kapeghian JC,el-Dean S,Bush M

更新日期：1985-01-01 00:00:00

abstract：:For many years, the ketogenic diet, including recent variants such the medium-chain triglyceride (MCT) diet, has been used with good clinical results in the management of refractory epilepsies, particularly in children. The antiepileptic effects of the diet, like the antiepileptic effects of starvation, have been attr...

journal_title：Medical hypotheses

authors： Mainardi P,Albano C

更新日期：2008-01-01 00:00:00

abstract：:The author reviews the criticism aimed at medical education and suggests that its shortcomings could be corrected by modifying the curriculum so that irrelevant material is eliminated and replaced in part with the humanities. ...

journal_title：Medical hypotheses

authors： Prioreschi P

更新日期：1980-05-01 00:00:00

abstract：:Epidemiological studies reveal that chronic alcoholics exhibiting liver disease are generally malnourished. Experimental studies unequivocally demonstrate that incidence of malnutrition cannot be avoided in animals fed liquid diets containing high concentrations of alcohol. Furthermore, ingestion of additional amounts...

journal_title：Medical hypotheses

authors： Sankaran H,Larkin EC,Rao GA

更新日期：1994-02-01 00:00:00

abstract：:The initial treatment for hypotension due to blood loss is intravenous fluids. Occasionally there is need for additional medication, as well as stopping the source of the bleeding. The literature in the main discusses the use of dopamine. Ephedrine has not been reviewed as useful in such situations. This article discu...

journal_title：Medical hypotheses

authors： Eldor J

更新日期：1991-07-01 00:00:00

abstract：:Natural objects, live and inanimate, actively maintain their entities by using their capacities (i.e., properties, internal resources, mechanisms, and experience) adequately to their needs. It is suggested that the principle of adequate function is a law of nature. ...

journal_title：Medical hypotheses

authors： Yabrov A

更新日期：1986-03-01 00:00:00

abstract：:SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19. Exploring compounds that could offer a breakthrough in treatment is the need of the hour. Re-positioning cheap, freely available and safe drugs is a priority. The paper proposes evidence for the potential use of diethylcarbamazine (DEC) in the treatm...

journal_title：Medical hypotheses

authors： Abeygunasekera A,Jayasinghe S

更新日期：2020-10-01 00:00:00

abstract：:The resonator theory claims that light scattering by the melanin granules of the retinal pigment epithelium causes light to be reflected back through the outer segment of the cones, in a direction opposite that of the incident light. These two opposite directed wave motions may produce standing waves inside the cone o...

journal_title：Medical hypotheses

authors： Bülow N

更新日期：1992-02-01 00:00:00

abstract：:Avascular necrosis of the femoral head (ANFH) is a common ailment characterized by necrosis of bone trabecular and bone marrow. It's mainly caused by the destruction of the blood supply in the femoral head and high rate of morbidity and disability is involved. Many methods have been tried including conservative treatm...

journal_title：Medical hypotheses

authors： Xu M,Peng D

更新日期：2011-02-01 00:00:00

abstract：:What causes cancer? To date, this question is left with no answer. The scientific community keeps defining cancer as a proliferation of cells in an uncontrolled and uncontrollable manner. The hypothesis developed here through an understanding of the cancer cell's behaviour led to its re-definition, providing answers t...

journal_title：Medical hypotheses

authors： Majerus MA

更新日期：2002-06-01 00:00:00

abstract：:Despite the widespread use of antidepressant medication, there are no signs that the burden of depression and suicide is decreasing in the industrialised world. This is generating mounting scepticism on the effectiveness of this class of drugs as an approach for the treatment of mood disorders. These doubts are also f...

journal_title：Medical hypotheses

authors： Procopio M

更新日期：2005-01-01 00:00:00

abstract：:The accepted paradigms of mainstream neuropsychiatry appear to be incompletely adequate and in various cases offer equivocal analyses. However, a growing number of new approaches are being proposed that suggest the emergence of paradigm shifts in this area. In particular, quantum theories of mind, brain and consciousn...

journal_title：Medical hypotheses

authors： Tonello L,Cocchi M,Gabrielli F,Tuszynski JA

更新日期：2017-04-01 00:00:00

abstract：:So-called 'limited life span' of diploid cells does not depend on their unresponsiveness to growth factors from the data obtained by complete protein-free culture of tumor cells. Limited proliferation (called limited life span) of diploid cells is one of the 'ad-hoc' negative regulatory mechanisms in animals, and can ...

journal_title：Medical hypotheses

authors： Chigira M,Watanabe H

更新日期：1993-10-01 00:00:00

abstract：UNLABELLED:T helper (Th) lymphocytes have been classified into distinct subsets, Th1 and Th2 on the basis of the cytokines they produce. According to the cross-regulatory properties of Th1 and Th2 cells, one would assume that to be affected by a Th1 type disease increases susceptibility to a Th1 type disease and inhibi...

journal_title：Medical hypotheses

authors： Shahabi S,Hassan ZM,Jazani NH,Ebtekar M

更新日期：2006-01-01 00:00:00

abstract：:Why is modern science less efficient than it used to be, why has revolutionary science declined, and why has science become so dishonest? One plausible explanation behind these observations comes from an essay First and second things published by CS Lewis. First Things are the goals that are given priority as the prim...

journal_title：Medical hypotheses

authors： Charlton BG

更新日期：2010-01-01 00:00:00