Association study of leukocyte telomere length and genetic polymorphism within hTERT promoter with type 2 diabetes in Bangladeshi population.

abstract：:Experiments with 5'-azacytidine and hematopoietic growth factor approved for the transformation of human mesenchymal cells into hematopoietic cells have demonstrated that cell fate can be dramatically altered by changing the epigenetic state of cells. Here, we demonstrate that umbilical cord-derived human mesenchymal ...

journal_title：Molecular biology reports

authors： Hu K,Xu C,Ni H,Xu Z,Wang Y,Xu S,Ji K,Xiong J,Liu H

更新日期：2014-07-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) is an important receptor tyrosine kinase member in animals, which plays versatile functions in development, growth, tissue regeneration etc. Current knowledge on EGFR is poor in bivalve mollusks. In this study, we cloned and analyzed an EGFR gene from the Pacific oyster Cras...

journal_title：Molecular biology reports

authors： Sun L,Huan P,Wang H,Liu F,Liu B

更新日期：2014-05-01 00:00:00

abstract：:It is well known that transcriptionally inactive rRNA genes are correlated with DNA hyper-methylation and histone hypo-methylation and there is clear evidence in humans that DNA and histone modification which alter chromatin structure are related to chromosome fragility. Very little is known about the biological cause...

journal_title：Molecular biology reports

authors： Singh M,Barman AS

更新日期：2013-01-01 00:00:00

abstract：:A reduction in the number of functional β-cells is the central pathological event in diabetes. Liver and ventral pancreas differentiates simultaneously in the same general domain of cells within embryonic endoderm. In addition, the precursor cell population being bi-potential may be targeted for either pancreas or liv...

journal_title：Molecular biology reports

authors： Sarkar S,Munshi C,Chatterjee S,Mukherjee S,Bhattacharya S

更新日期：2019-10-01 00:00:00

abstract：:Osteoporosis is a common health problem in Mexico, so it is essential to investigate the status of different gene polymorphisms that could serve as genetic susceptibility markers in the Mexican population. Genes with a role in bone metabolism are excellent candidates for association studies. In this study were determi...

journal_title：Molecular biology reports

authors： Falcón-Ramírez E,Casas-Avila L,Cerda-Flores RM,Castro-Hernández C,Rubio-Lightbourn J,Velázquez-Cruz R,Diez-G P,Peñaloza-Espinosa R,Valdés-Flores M

更新日期：2013-03-01 00:00:00

abstract：:A Cys2/His2-type zinc finger protein gene, DgZFP, was isolated from chrysanthemum by rapid amplification of cDNA ends (RACE) approach. The DgZFP encodes a protein of 211 amino acids residues with a calculated molecular mass of 22.9 kDa and theoretical isoelectric point is 8.59. DgZFP contains two Cys2/His2-type zinc f...

journal_title：Molecular biology reports

authors： Liu QL,Xu KD,Ma N,Zeng L,Zhao LJ

更新日期：2010-02-01 00:00:00

abstract：:Expression of recombinant proteins is a standard technique in molecular biology and a wide variety of prokaryotic as well as eukaryotic expression systems are currently in use. A limiting step is often the purification of the expressed recombinant protein, particularly if mammalian expression systems that yield low ex...

journal_title：Molecular biology reports

authors： Schmitt J,Hess H,Stunnenberg HG

更新日期：1993-10-01 00:00:00

abstract：:Insulin-like growth factor (IGF) expression plays a critical role in the endocrine regulation of proliferation, differentiation, and growth in shellfish as well as in fish. The Pacific oyster, Crassostrea gigas, is a significant aquaculture species that comprises a large percentage of the Korean shellfish industry; mo...

journal_title：Molecular biology reports

authors： Moon JS,Choi YH

更新日期：2019-02-01 00:00:00

abstract：:According to the stem cell theory for cancer, hepatocellular carcinomas are sustained by a group of cancer stem cells (CSCs) which are responsible for resistance to chemotherapy. In the present study we aimed to examine lipid metabolism in cancer stem cells induced by long-term treatment with sorafenib and its relatio...

journal_title：Molecular biology reports

authors： Bort A,Sánchez BG,de Miguel I,Mateos-Gómez PA,Diaz-Laviada I

更新日期：2020-04-01 00:00:00

abstract：:The lily-of-the-valley Convallaria (Asparagaceae) consists of three herbaceous perennial species. The plants are commonly found in northern hemisphere, and are best-known for their ornamental and pharmaceutical value. In order to assess the genetic structure, diversity and demographic history of Convallaria species, 1...

journal_title：Molecular biology reports

authors： Lu QX,Gao J,Wu JJ,Zhou X,Wu X,Li MD,Wei YK,Wang RH,Qi ZC,Li P

更新日期：2020-04-01 00:00:00

abstract：:The binding of acridine orange and ethidium bromide to rat liver chromatin increases by 30% one hour after partial hepatectomy, returns to the control level by the second hour and increases again by the sixth hour. The changes described were found in investigations carried out on whole cells, on isolated nuclei, and o...

journal_title：Molecular biology reports

authors： Sondore OY,Fedoseeva GE,Kadyckov VA,Zelenin AV

更新日期：1978-10-16 00:00:00

abstract：:We reported earlier about the detection of a chromosomally located arsenic operon (arsRBC) in a gram-negative bacterium Pseudomonas fluorescens strain MSP3, which showed resistance to elevated levels of sodium arsenate and sodium arsenite. The genes for arsenic resistance were cloned into the HindIII site of pBluescri...

journal_title：Molecular biology reports

authors： Prithivirajsingh S,Mishra SK,Mahadevan A

更新日期：2001-01-01 00:00:00

abstract：:Hsa-mir-143 and hsa-let-7c have been reported to be deregulated in multiple neoplasms. The main purpose of this study was to investigate the expression of these miRNAs in bladder cancer (BCa) and to analyze the association between their expression profiles and clinical and epidemiological parameters. Ninety BCa specim...

journal_title：Molecular biology reports

authors： Boubaker NS,Spagnuolo M,Trabelsi N,Said R,Gurtner A,Regazzo G,Ayed H,Blel A,Karray O,Saadi A,Rammeh S,Chebil M,Rizzo MG,Piaggio G,Ouerhani S

更新日期：2020-02-01 00:00:00

abstract：:Nuclear magnetic resonance (NMR) spectroscopy is a useful biophysical technique to study the ligand-protein interaction. In this report, we have used bacterially produced ERβ and its domains for studying the functional analysis of ligand-protein interaction. Briefly, ERβ and its transactivation domain (TAD) and ligand...

journal_title：Molecular biology reports

authors： Paramanik V,Thakur MK

更新日期：2011-10-01 00:00:00

abstract：:Molluscs are an extraordinarily diverse group of animals and to discriminate them based on one molecular marker/gene is very difficult because of the too fast or slow rate of nucleotide substitution. In the study, the tropomyosin cds (coding sequences) of 43 animal species were analyzed, the results of which suggested...

journal_title：Molecular biology reports

authors： Wang X,Li L,Xu F,Zhang G

更新日期：2011-10-01 00:00:00

abstract：:Cotton fiber cells elongate without dividing to form economically valuable spinnable fiber. Reports of the ploidy level of fiber cells are variable. Early reports indicated an increase in nuclear DNA content in young fibers; however, subsequent reports failed to observe such a significant increase in ploidy level. Eva...

journal_title：Molecular biology reports

authors： Taliercio E,Ray J,Scheffler J

更新日期：2010-02-01 00:00:00

abstract：:To determine whether methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms are associated with pre-eclampsia susceptibility. Literature searches of the Pubmed, Embase, BIOSIS Previews and Web of Science were conducted to identify all eligible articles up to January 18th, 2013. The pooled odds rati...

journal_title：Molecular biology reports

authors： Li X,Luo YL,Zhang QH,Mao C,Wang XW,Liu S,Chen Q

更新日期：2014-08-01 00:00:00

abstract：:The researches on yak genetics and breeding were extremely restricted due to lacking of reliable DNA molecular markers. The microsatellites with repeat motif (AC)n/(GT)n in yak genome were enriched by Dynal magnetic beads and the gene libraries containing (AC)n/(GT)n were constructed. Among the 92 identified and seque...

journal_title：Molecular biology reports

authors： Cai X,Mipam T,Zhao F,Sun L

更新日期：2014-06-01 00:00:00

abstract：:Groups of CBA mice were administered [35S] methionine (1 mCi/mouse). Non-histone proteins, H1 and H1(0) histones and nucleosomal core histones were isolated from different issues by selective extractions. The measurements of radioactivity of individual bands and autoradiography of dry gels were used to identify methio...

journal_title：Molecular biology reports

authors： Medvedev ZA,Medvedeva MN

更新日期：1988-01-01 00:00:00

abstract：:As initial steps to define how the 26S proteasome degrades ubiquitinated proteins in plants, we have characterized many of the subunits that comprise the proteolytic complex from Arabidopsis thaliana. A set of 23 Arabidopsis genes encoding the full complement of core particle (CP) subunits and a collection encoding 12...

journal_title：Molecular biology reports

authors： Fu H,Girod PA,Doelling JH,van Nocker S,Hochstrasser M,Finley D,Vierstra RD

更新日期：1999-04-01 00:00:00

abstract：:Tetrahydrobiopterin (BH4) is an essential cofactor for aromatic acid hydroxylases, which control the levels of monoamine neurotransmitters. BH4 deficiency has been associated with many neuropsychological disorders. Dihydrofolate reductase (DHFR) can catalyze 7,8-dihydrobiopterin to 5,6,7,8-tetrahydrobiopterin (BH4) in...

journal_title：Molecular biology reports

authors： Wang W,Gao J,Wang J,Liu C,Meng Y

更新日期：2012-12-01 00:00:00

abstract：:45S ribosomal precursor RNA and large heterogeneous RNA molecules (greater than 45S) extracted from human leukemic cells were incubated in vitro with purified RNase III, which specifically attacks double-helical RNA regions. About 50% of the ribosomal precursor was cleaved into two major fragments sedimenting at 28S a...

journal_title：Molecular biology reports

authors： Torelli UL,Ferrari S,Torelli GM,Cadossi R,Ferrari S,Montagnani G,Narni F

更新日期：1977-12-01 00:00:00

abstract：:Oxidative stress plays a major role in myocardial injury. Morin, a bioflavonoid has known to possess various biological activities in previous studies. Hence, this study evaluated the cardioprotective mechanism(s) of Morin against isoproterenol induced myocardial necrosis in rats. Male albino Wistar rats were divided ...

journal_title：Molecular biology reports

authors： Verma VK,Malik S,Narayanan SP,Mutneja E,Sahu AK,Bhatia J,Arya DS

更新日期：2019-02-01 00:00:00

abstract：:Myocardial ischemia and reperfusion (MI/R) is associated with an intense inflammatory reaction, which may lead to myocyte injury. In this study, we investigated the effect of quercetin, an inhibitor of c-Jun N-terminal kinase on ischemia/reperfusion injury in isolated rat hearts. Rat models of MI/R were induced by cor...

journal_title：Molecular biology reports

authors： Jin HB,Yang YB,Song YL,Zhang YC,Li YR

更新日期：2012-12-01 00:00:00

abstract：:The aim of this study was to determine whether tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) promoter polymorphisms confer susceptibility to periodontitis in ethnically different populations. A literature search was performed using PubMed and Embase and a meta-analysis of the identified studies was conducte...

journal_title：Molecular biology reports

authors： Song GG,Choi SJ,Ji JD,Lee YH

更新日期：2013-08-01 00:00:00

abstract：:Movement assisted by muscles forms the basis of various behavioural traits seen in Drosophila. Myogenesis involves developmental processes like cellular specification, differentiation, migration, fusion, adherence to tendons and neuronal innervation in a series of coordinated event well defined in body space and time....

journal_title：Molecular biology reports

authors： Dubey M,Ain U,Firdaus H

更新日期：2020-12-01 00:00:00

abstract：:The association between vitamin D receptor (VDR) gene polymorphisms and risk of benign prostatic hyperplasia (BPH) has been investigated in numerous publications, but published results remain inconclusive. Hence, we conducted this meta-analysis to derive a more precise conclusion. Four polymorphisms (Taq-I, Bsm-I, Apa...

journal_title：Molecular biology reports

authors： Zeng XT,Yao QS,Weng H,Li S,Huang JY,Wang XH

更新日期：2014-10-01 00:00:00

abstract：:Growth hormone-releasing hormone receptor (GHRHR) has important functions in the regulation of the growth hormone axis and the development and proliferation of pituitary somatotropes. Moreover, some mutations in mouse GHRHR can induce the dwarfism. The objective of this paper is to reveal the association of GHRHR with...

journal_title：Molecular biology reports

authors： Zhang CF,Chen H,Zhang ZY,Zhang LZ,Yang DY,Qu YJ,Hua LS,Zhang B,Hu SR

更新日期：2012-12-01 00:00:00

abstract：:In the present study, we investigated the differentially expressed proteins associated with ulcerative colitis (UC) using proteomic methods. Two-dimensional electrophoresis (2-DE) technology was performed to separate the total proteins of ulcerative tissues from those of the normal tissues of UC patients. PDQuest soft...

journal_title：Molecular biology reports

authors： Li N,Wang X,Zhang Y,Zhai J,Zhang T,Wei K

更新日期：2012-05-01 00:00:00

abstract：:Protein phosphorylation is one of the most fundamental types of post-translational modifications and it plays a vital role in various cellular processes of eukaryotes. Among three types of phosphorylation i.e. serine, threonine and tyrosine phosphorylation, tyrosine phosphorylation is one of the most frequent and it i...

journal_title：Molecular biology reports

authors： Khan YD,Rasool N,Hussain W,Khan SA,Chou KC

更新日期：2018-12-01 00:00:00