Abstract：
INTRODUCTION:COVID-19 is an emerging, rapidly evolving global situation, infecting over 25 million people and causing more than 850,000 deaths. Several signs and symptoms have been described to be characteristic of the disease. However, there is a dearth of report on the description of the clinical characteristics of the disease in patients from Nigeria. This study was designed to provide a description of the clinical and demographic characteristics of COVID-19 patients in Nigeria. METHODS:This study is a case series that includes patients that are evaluated between May and August 2020, and diagnosed with COVID-19. Patient health records were reviewed and evaluated to describe the clinical characteristics on presentation. RESULTS:A total of 154 COVID-19 patients were included in this study, with a mean age (S.D.) of 46.16 (13.701). Most of the patients survived (mortality rate of 2.6%), and were symptomatic (89.6%). There were more males (74.7%) than females, and the most common symptoms were fever, breathing difficulty, dry cough and malaise. Co-morbidities were also present in almost half of the study participants (49.4%). CONCLUSION:This study presents the most extensive description, to date, on the clinical and demographic characteristics of COVID-19 patients in Nigeria. Males are more likely than females to be infected with COVID-19 and the most occurring symptoms are fever, breathing difficulty, malaise, dry cough and chest pain. Old age and the presence of co-morbidities may also be associated with developing the severe disease.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Otuonye NM,Olumade TJ,Ojetunde MM,Holdbrooke SA,Ayoola JB,Nyam IY,Iwalokun B,Onwuamah C,Uwandu M,Abayomi A,Osibogun A,Bowale A,Osikomaiya B,Thomas B,Mutiu B,Odunukwe NNdoi
10.1016/j.jnma.2020.11.011subject
Has Abstractpub_date
2020-12-22 00:00:00eissn
0027-9684issn
1943-4693pii
S0027-9684(20)30430-2pub_type
杂志文章abstract：:To minimize the incidence of postoperative infections in patients undergoing open-heart surgery, antibiotics should maintain tissue concentrations greater than the minimal inhibitory concentration (MIC) for potential pathogens (eg, Staphylococcus) for the duration of the operation. The ability of cefonicid, a new β-la...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：:Obesity is on the rise worldwide. An obesity subtype, metabolically healthy obese (MHO), is resilient to unfavorable metabolic and cardiovascular effects. Factors predicting MHO phenotype are not well characterized. We aimed to identify MHO and metabolically unhealthy obese (MUO) children and adolescents with respect ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.02.008
更新日期：2017-10-01 00:00:00
abstract：:Trichinosis is world-wide in distribution, occurring in tropical, temperate, and polar regions. Although incidence of the disease appears to be declining in most regions, it is still widely distributed in Europe and is increasing in many parts of Africa. In recent years, the incidence of trichinosis in the United Stat...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1983-06-01 00:00:00
abstract：:Previous studies document the importance of religious involvement in African-American communities. This study examines the extent to which religious involvement is associated with health status among African-American males. The data come from a community sample of 537 males residing in a major US urban area. Three ind...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Clinical and pathological findings in 15 patients with carcinoma of the midthoracic esophagus were analyzed. The author concluded that preoperative radiotherapy reduces tumor size and improves resectability. Longer follow-up is required to determine whether or not preoperative radiotherapy improves survival rates in t...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:In the past the study of the allocation of scarce medical resources centered around "high-tech" forms of health care, such as the use of the artificial heart and hemodialysis. The use of nonbiomedical criteria (ie, should the social worth or financial status of a particular patient dictate preferential treatment over ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：:Opioid use disorder (OUD) constitutes a significant public health burden as opioid overdose deaths have continued to rise in the United States. Although treatment modalities are available to manage OUD, some patients experience challenges achieving their OUD management goals. Some of these challenges may be attributab...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.09.006
更新日期：2019-12-01 00:00:00
abstract：:A questionnaire was developed to assess religiously based moral beliefs about acquired immunodeficiency syndrome. The questionnaire was administered to a group of primarily black physicians, a selection of freshman medical students, two groups of clergy representing contrasting philosophical orientations, a group of y...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：:Three different noninvasive imaging procedures were performed in a patient after an intravenous pyelogram suggested a suprarenal mass. Presence of a mass was confirmed by ultrasonogram. Computed tomography revealed two masses in the splenic bed that showed contrast enhancement. Radionuclide scans demonstrated multiple...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：:As part of an effort to better educate patients about using condoms, a survey was done to assess the sexual practices, attitudes toward acquired immunodeficiency syndrome (AIDS) and condom use by patients who visit an urban family practice center. A self-administered questionnaire was given to 126 patients of whom the...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:We prospectively studied the evolution of HBsAg antibody (HBsAb) after primary vaccination (four doses; Engerix B, 40 pg i.m at 0, one, two and six months) in 29 patients who were seronegative (HBsAb <10 IU/L), had not been previously vaccinated and were on hemodialysis. Their mean age was 45.58 +/- 10.98 years, and t...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：:Prehospital delay is an important cause of out-of-hospital coronary mortality. To determine the effects of decision time delay in a patient population comprised mainly of blacks and the underprivileged, 74 consecutive patients with acute chest pain necessitating admission to the coronary care unit in a large urban hos...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1993-03-01 00:00:00
abstract：:Vitamin D deficiency has been linked to fracture risk and chronic musculoskeletal pain. Adults with sickle cell disease have a high prevalence of low bone density and chronic pain with poorly defined etiologies. We recognized that vitamin D deficiency may represent a treatable etiology and sought to determine the prev...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,多中心研究
doi：10.1016/s0027-9684(15)30605-2
更新日期：2010-04-01 00:00:00
abstract：:Renal medullary carcinoma (RMC) is a rare but highly aggressive neoplasm that primarily affects young African Americans with sickle cell trait. Most patients present with macroscopic hematuria and have metastases at diagnosis. Chemotherapy, biologics directed against the more common renal cell carcinomas and radiation...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2016.08.006
更新日期：2017-04-01 00:00:00
abstract：:Painful palmar and plantar erythema is an uncommon systemic complication of chemotherapy and has been reported in association with methotrexate, cystosine arabinoside, doxorubicin, and 5-fluorouracil. The authors report a case in which the syndrome was precipitated by hepatic artery infusion of 5-FUdR. The previous re...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：BACKGROUND:Pregnant women with sickle cell disease (SCD) are at increased risk of maternal and fetal complications. There are limited data on the outcome of the treatment of VOCs with opioids in relation to neonatal complications during pregnancy. METHODS:This is a retrospective cohort study of women with SCD from Jan...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.04.002
更新日期：2018-04-01 00:00:00
abstract：:Primary lymphoma of the central nervous system (CNS) is difficult to diagnose because of the difficulty in differentiating it from multiple sclerosis, sarcoidosis, metastatic disease, chronic granulomatous disease, and cerebral cysticercosis. With the patient presented in this report, no abnormalities were found after...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：OBJECTIVES:Intimate partner violence (IPV)during pregnancy is a significant public health problem. Approximately 324,000 IPV victimizations occur during pregnancy each year. However, research on the impact of IPV on birth outcomes yields conflicting findings. This study examines the association of IPV with birth outcom...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.06.017
更新日期：2017-01-01 00:00:00
abstract：:Invasive techniques continue to be used in monitoring and treating the critically ill patient in spite of preference for, and increasing use of, non-invasive or minimally invasive techniques. With or without simultaneous determination of left ventricular filling pressure, the central venous pressure (CVP) catheter is ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1977-05-01 00:00:00
abstract：:An analysis of the articles published in 1992 in the Journal of the National Medical Association (JNMA) was performed to assess the content, statistical analysis, and the profile of its contributors. Seventy-six articles were reviewed. The majority of the articles focused on biomedical aspects of health; however, a si...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：BACKGROUND:High sensitivity C-reactive protein (hsCRP) and Plasminogen Activator Inhibitor-1 (PAI-1) are recognised independent novel risk factors for cardiovascular disease. Few studies have assessed cardiovascular risk factors in patients with hyperglycaemic emergencies (HE), despite it being a major cause of death i...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.12.004
更新日期：2020-02-01 00:00:00
abstract：:Schistosomiasis is a common parasitic disease in the tropical and subtropical regions of Africa, Asia, South America and the Caribbean. It is the second most common parasitic infection of humans after malaria. Acute and chronic clinical presentations of S. monsoni are well described. Presentation as a pseudotumor is c...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVE:To study racial disparities and the weapons used to commit youth homicide in New Jersey. METHODS:The homicide data were obtained from New Jersey death certificate files, 1989-1997. RESULTS:There was a statistically significant racial disparity in homicide incidence rates in this study. The homicide incidenc...
journal_title：Journal of the National Medical Association
pub_type： 社论
doi：
更新日期：2004-04-01 00:00:00
abstract：:A 5-year-old boy with purpura fulminans (PF) was successfully managed with a protocol in which fresh frozen plasma (FFP) was administered, followed by a trial of certain therapeutic agents. This approach was based upon combined experience both with the reference patient and with a subject with a chronic form of PF. FF...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章
doi：
更新日期：1983-08-01 00:00:00
abstract：:Quit-rates for cigarette smokers in a lifestyle intervention program aimed at reducing coronary risk were 24 percent for all participants and 34 percent for non-dropouts. Recidivism remained very low during participation in the program. Half of the smokers who quit did so after being in the program more than two years...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-04-01 00:00:00
abstract：:Liposuction (suction-assisted lipectomy) is today an accepted, closed surgical technique utilized by physicians practicing in a number of different specialties. It is a procedure that can be learned and used as an adjunct to a number of open procedures, including rhytidectomy and abdominoplasty.THE TWO PRINCIPAL KEYS ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1987-12-01 00:00:00
abstract：BACKGROUND:This study was a randomized trial to test the impact of an informed decision-making intervention on prostate cancer screening use. METHODS:The study population included 242 African-American men from three primary care practices who were 40-69 years of age and had no history of prostate cancer. Participants ...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2005-08-01 00:00:00
abstract：:The psychosomatic disorder termed Munchausen's syndrome has gained official recognition in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, in which it is referred to as a "chronic factitious disorder with physical symptoms." Sporadic case reports have been published over t...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:Anorexia nervosa has been considered rare or nonexistent among blacks. A report of the presentation and clinical course of this disorder in two black female adolescents illustrates a serious medical psychiatric problem that may be increasingly detected among predisposed teenagers of the black middle and professional c...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1984-01-01 00:00:00
abstract：:The three leukotriene (LT) modifiers approved for use in the United States, zileuton, zafirlukast, and montelukast, are the first new class of therapeutic agents to be introduced in 20 years for the treatment of asthma. These agents are referred to as leukotriene modifiers and have clearly demonstrated the ability to ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1999-08-01 00:00:00
