Abstract：
BACKGROUND:Pregnant women with sickle cell disease (SCD) are at increased risk of maternal and fetal complications. There are limited data on the outcome of the treatment of VOCs with opioids in relation to neonatal complications during pregnancy. METHODS:This is a retrospective cohort study of women with SCD from January 1999 to December 2008. Women with SCD were identified by ICD-9 codes and matched 2:1 to a control group of women on methadone for opioid dependence. The primary outcome was the rate of neonatal abstinence syndrome (NAS). Secondary outcomes included the mean NAS score prior to treatment and the length of treatment. Statistical analysis was performed using SPSS. RESULTS:Twenty-one women with SCD who delivered a total of 23 neonates were included. The rate of NAS among infants born to women with SCD who were treated with opioids at any time was 22% compared to 54% in the methadone controls (p = .010). The rate of NAS was 27% among infants born to women taking opioids daily compared to 54% in the methadone control group (p = .062). CONCLUSIONS:Neonates born to women with SCD who are treated with daily opioids are at a similar risk for developing NAS as those born to mothers on methadone for opioid dependence. Neonates born to women with SCD treated with episodic opioids are at a significantly lower risk for developing NAS than those born to women on methadone for opioid dependence.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Nnoli A,Seligman NS,Dysart K,Baxter JK,Ballas SKdoi
10.1016/j.jnma.2017.04.002subject
Has Abstractpub_date
2018-04-01 00:00:00pages
163-168issue
2eissn
0027-9684issn
1943-4693pii
S0027-9684(16)30106-7journal_volume
110pub_type
杂志文章abstract：OBJECTIVE:A retrospective observational study was done to describe the clinical and pathological profile of gastrointestinal stromal tumors (GISTs) in Afro-Caribbean patients at a tertiary care referral center over a 5-year period. RESULTS:Eighteen cases of GIST were identified over the period under review. Male to fe...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30122-x
更新日期：2012-01-01 00:00:00
abstract：:The harmful effects of tobacco use and nicotine are well known. There is strong epidemiological evidence for smoking as a risk factor for cancer of the lung and oral cavity. The evidence for second-hand smoke as a risk factor for breast cancer is rapidly accumulating. The anthracycline doxorubicin is used in the treat...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND/PURPOSE:With the urgency to create more equitable health care, increased research and early exposure to health interventions and clinical medicine are imperative. Health disparities continue to persist nationwide, particularly in underserved areas and among traditionally disadvantaged populations. In additio...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.12.003
更新日期：2020-02-01 00:00:00
abstract：:The task of developing a body of knowledge about specific problems, both intrapsychic and psychosocial, which influence a black executive's maturation, must be initiated. There is currently a definite interest, among black executives, in obtaining access to appropriate psychotherapeutic intervention. A psychobiographi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-03-01 00:00:00
abstract：:Although gastric cancer has not been reported in association with pregnancy, the authors encountered it in a paraplegic young pregnant woman presenting with gastric outlet obstruction.Fiberoptic gastroscopy and biopsy provided the surprising tissue diagnosis. Ultrasound was helpful in assessing the size and position o...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Twenty-one patients with postpolio syndrome were surveyed to determine otolaryngologic symptoms. An alteration in voice, dysphagia, and fatigue were the most common symptoms reported. Prevailing etiologic theories are presented, and treatment recommendations are offered. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:Smooth muscle tumors are uncommon lesions of the vulva and represent a variety of histologic types. When encountered, surgical treatment is guided by the malignant potential of the tumors. This article presents the case of a 45-year-old woman who underwent conservative excision of a 10-cm vulvar lesion consistent with...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Climatic conditions may trigger subclinical disease in predisposed individuals and also exacerbate eczematous symptoms resulting in persistence or increased frequency of atopic dermatitis (AD) flares. The aim of this study is to assess the impact of tropical weather conditions on the frequency at which atopi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2018.06.005
更新日期：2019-02-01 00:00:00
abstract：:An overview of psychiatric disorders seen in older patients is reviewed. Dementing illnesses are discussed. A specific method of assessing the patient with cognitive decline in a clear sensorium is presented. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：PURPOSE:This article highlights issues of misdiagnosis in an African-American, adult clinical population by doing point prevalence, record review study within a comprehensive community mental health center. METHOD:Psychiatric evaluations of 330 patients were reviewed and clinically identifiable variables of: a) childh...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/S0027-9684(15)30048-1
更新日期：2015-03-01 00:00:00
abstract：STUDY OBJECTIVE:Health literacy influences a patient's ability to read and understand labels on medicine containers, appointment slips, informed-consent documents and medical instructions--all of which are considered basic health documents that a patient encounters in healthcare settings. Previous research suggests Spa...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31512-1
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND:Black women are more likely to have bacterial vaginosis (BV) than are non-Hispanic white women. We examined whether this disparity can be explained by racial differences in known BV risk factors. METHODS:Nine hundred black and 235 white women were enrolled from five US sites. At baseline, structured intervi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：ISSUES:Tobacco Control remains one of the greatest determinants for reducing the morbidity and mortality of African Americans. OBJECTIVE:To examine the scope and consequences of tobacco use among African Americans and characterize its implications for the National Medical Association physician membership and their pat...
journal_title：Journal of the National Medical Association
pub_type： 共识发展会议,杂志文章,评审
doi：
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVE AND AIM:Most studies have detected impairment of gallbladder motility among obese compared with nonobese people. However, the relationship between gallbladder motility and weight loss is not well defined. The aim of this study was to evaluate the relationship between percent of weight loss and gallbladder mot...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：:This article reports a rare case of primary signet-ring cell carcinoma of the bladder with transitional cell and adenocarcinoma variants and metachronous metastases to the penis and lungs. This combination of lesions has not previously been reported. Together, they portend widespread dissemination and an early demise ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:A rare case of primary melanoma of the cervix is reported. The patient presented with vaginal bleeding and was thought to have a degenerated cervical fibroid. A radical hysterectomy with pelvic node dissection was performed and followed postoperatively with chemotherapy (phenylalanine mustard). The patient died within...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1981-12-01 00:00:00
abstract：:From 1967 to 1977, 72 patients with small cell carcinoma of the lung were seen. Thirty-five of these patients had unilaterally localized lesions (limited disease) and were treated with cobalt 60 radiation therapy (6,000 rad in six weeks) followed by chemotherapy consisting of cyclophosphamide (Cytoxan), vincristine, m...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:Trichinosis is world-wide in distribution, occurring in tropical, temperate, and polar regions. Although incidence of the disease appears to be declining in most regions, it is still widely distributed in Europe and is increasing in many parts of Africa. In recent years, the incidence of trichinosis in the United Stat...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1983-06-01 00:00:00
abstract：OBJECTIVE:To assess differences in self-reported health status and satisfaction between African-American and caucasian veterans with ischemic heart disease (IHD). DATA SOURCES/STUDY SETTING:African-American and caucasian patients enrolled in General Internal Medicine clinics at six Veteran Affairs Medical Centers. ST...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:Although there have been studies examining HIV knowledge among college population, current study is the first providing comparable information on HIV knowledge in general and testing specifically via online surveys among black and white college students. METHODS:Blacks (N=222) were recruited from 15 histori...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31377-8
更新日期：2008-07-01 00:00:00
abstract：:This article describes a required primary care curriculum for all third and fourth year medical students at the Drew/UCLA Medical Education Program. The curriculum is a supplement to the traditional medical school clinical requirements. Key features of the primary care core curriculum in the third year include a weekl...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms that account for 0.2% of all GI neoplasms. We report a case of a 62-year-old male with a large esophageal GIST, and discuss the pathophysiology of the disease and the current management principles. This case is noteworthy because it documents a rar...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30933-0
更新日期：2009-05-01 00:00:00
abstract：:This report describes a case of tuberculosis with an atypical presentation characterized by epididymitis and Addison's disease in the absence of lung involvement. A 54-year-old male who presented with acute right scrotal pain and a whitish discharge, had been diagnosed four months earlier with acute epididymitis and p...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:The rare association of protease inhibitor deficiency (Pi(zz) genotype) in a black American with chronic, obstructive pulmonary disease due to asthmatic bronchitis, rather than basal pan lobular emphysema, is presented. The late onset of symptoms, despite environmental exposures, is also unusual in this homozygote, as...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:This article describes the 6-week Health Careers Enhancement Program for Minorities inaugurated in the summer of 1988 at Case Western Reserve University School of Medicine. The program was developed for minority and economically disadvantaged college undergraduates and postbaccalaureate premedical students. Its major ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1990-12-01 00:00:00
abstract：:A case of sickle cell disease with 63 documented episodes of priapism that were managed medically is presented. The case is very unusual because of the fact that despite so many episodes of priapism, he did not lose sexual potency. On the contrary, over a period of time, his penis hypertrophied. To the best of our kno...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Detection of intra-abdominal abscesses by computed tomography (CT) has an estimated accuracy rate of greater than 90 percent. Features helpful in detecting these abscesses include extraluminal gas, the "rind" sign, airfluid interface, and low and high density areas. The author presents three cases to illustrate the us...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1985-08-01 00:00:00
abstract：:Within 50 years, if current trends continue, 50 million elderly Americans will suffer visual impairment from macular degeneration or cataract. However, available evidence indicates that this impending crisis of visual health can be minimized by a simple, safe, inexpensive, and practical means of prevention. Cataract a...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:The purpose of this report is to review personal experience with digital palpation of the nasopharynx, particularly as it relates to an apparently reversible posterior pharyngeal mass commonly found in patients who are heavy smokers. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：:Quit-rates for cigarette smokers in a lifestyle intervention program aimed at reducing coronary risk were 24 percent for all participants and 34 percent for non-dropouts. Recidivism remained very low during participation in the program. Half of the smokers who quit did so after being in the program more than two years...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-04-01 00:00:00
