Abstract：
:A 5-year-old boy with purpura fulminans (PF) was successfully managed with a protocol in which fresh frozen plasma (FFP) was administered, followed by a trial of certain therapeutic agents. This approach was based upon combined experience both with the reference patient and with a subject with a chronic form of PF. FFP controlled the acute disseminated intravascular coagulation in both instances and permitted venous antithrombotic drugs to be evaluated in safety. The PF syndrome in the index case was found to be heparin responsive, while the atypical case was coumarin responsive (heparin resistant). Initial administration of FFP was recommended rather than heparin in order to minimize the risk of hemorrhage while maintaining the likelihood of a swift response. When FFP is effective, a sequential trial should be undertaken with agents from the following categories: (1) venous antithrombotic, (2) antiplatelet, (3) antifibrinolytic, and (4) antiproteolytic. This process permits therapies to be thoroughly tested and used as investigative probes into the mechanisms of a particular case of PF. Should FFP prove ineffective, the list can serve as a guide for the investigation of various fastacting agents in the acute phases of disseminated intravascular coagulation. PF treatments are ranked in accordance with the number of positive outcomes in the literature.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Branson HE,Katz Jsubject
Has Abstractpub_date
1983-08-01 00:00:00pages
821-5issue
8eissn
0027-9684issn
1943-4693journal_volume
75pub_type
临床试验,杂志文章abstract：OBJECTIVE:To discuss the complication of pneumothorax from alveolar rupture after transtracheal high-frequency jet ventilation and to present a case of pneumothorax, pneumomediastinum and pneumoperitoneum after jet ventilation coupled with use of the microdebrider. METHOD:Detailed case report. RESULTS:Unilateral pnue...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:A 64-year-old man got trismus and trigeminal neuralgia under the diagnosis of colon cancer with mandibular metastasis after emergency appendectomy and elective hemicolectomy. The patient chose to forgo further surgery and was given only palliative chemotherapy and radiotherapy. He died six months after diagnosis. Meta...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31353-5
更新日期：2008-06-01 00:00:00
abstract：:Posterior reversible encephalopathy syndrome (PRES) in sickle cell patients has been rarely reported previously in the setting of severe crisis or uncontrolled hypertension. Here, we report a rare and unusual case of recurrent PRES in a young adult sickle cell patient without any obvious precipitating factors. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30267-4
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVE:To identify predictors of compliance with antihypertensive combination therapy in a Medicaid population. METHODS:Retrospective medical and pharmacy claims data for Maryland Medicaid patients receiving angiotensin converting enzyme inhibitors (ACEls)/hydrochlorothiazides (HCTZs) or ACEl/calcium channel blocke...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30808-7
更新日期：2009-01-01 00:00:00
abstract：:Case reports concerning rare complications of human bite injuries are uncommon in the literature. Further, rehabilitation of the resultant dysfunction is also hardly reported. A 41-year-old housewife who had had a human bite during an altercation 6 months ago was referred to the rehabilitation department with a nonfun...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30856-7
更新日期：2009-03-01 00:00:00
abstract：:Baylor College of Medicine has conducted a summer enrichment program for minority/disadvantaged premedical students since 1969. Follow-up data on medical school application and acceptance for participants from 1980 through 1984 were analyzed in relation to selected preprogram variables--cumulative college grade point ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Forty-two patients with renal cell carcinoma were evaluated with computerized tomography (CT) followed by surgical exploration, extirpative surgery, or autopsy to determine the accuracy of the CT scan in assessing the extension of the disease. There was an overall accuracy of 95 percent (40/42 patients). The two stagi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-06-01 00:00:00
abstract：:An association between the factors of low birth weight and fetal growth retardation and subsequent risk of cardiovascular disease has been proposed; this is the basis of the "thrifty phenotype" hypothesis described in relation to type 2 diabetes mellitus. The relationship between height, presumably an indicator of ear...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:This article reviews diagnosis and management of infants with diabetes. These infants present with signs and symptoms confused with other more common illnesses in this age group. A physician examining an ill-appearing dehydrated infant, without any obvious cause for the dehydration, should quickly screen the urine for...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND:It is commonly perceived that patients with sickle cell disease have increased hospital length of stay (LOS) because of mental health issues, including depression and drug-seeking behavior. However, the effect of mental and physical functional status on acute care resource use is unknown. OBJECTIVE:To asses...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30826-9
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:This study investigates whether racial/ethnic disparities in childhood asthma prevalence can be explained by differences in family and neighborhood socioeconomic position (SEP). METHODS:Data were from the 2001 Rhode Island Health Interview Survey (RI HIS), a statewide representative sample of 2,600 Rhode Isl...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-02-01 00:00:00
abstract：:Five patients with a diagnosis of rectal carcinoma were examined by magnetic resonance and computerized tomography (CT) to determine if magnetic resonance imaging (MRI) added any information to that obtained by computerized tomography. In each case, the imaging studies agreed with the surgical description of the tumor...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：OBJECTIVES:To assess the prevalence of vitamin D deficiency among patients in an inner-city practice with a large African American population, and to evaluate the efficacy of vitamin D replacement as part of routine care. METHODS:A chart review was undertaken to identify patients aged 18 years and more with at least o...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30337-0
更新日期：2011-05-01 00:00:00
abstract：:A left testicular mass was found in a 34-year-old black man with a history of multisystem sarcoidosis of 7½ years duration. Microscopic examination of the excised testicle revealed noncaseating granulomas throughout, as well as a few such lesions in the epididymis. This is the seventh reported, microscopically proven ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:Dyslipidemia is among the most significant risk factors of cardiovascular disease. Many patients with dyslipidemia fail to meet certain therapeutic targets as a result of clinical inertia. AIMS:To explore the views and opinions of physicians who often see and provide healthcare to patients with dyslipidemia...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2018.04.002
更新日期：2019-02-01 00:00:00
abstract：:A 31-year-old black man presented with bilateral multiple renal papillary adenocarcinomas. The patient had been maintained on captopril therapy for severe hypertension for three years. The possibility of drug-induced malignancy is discussed. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：OBJECTIVE:A pilot study to determine whether prenatal and neonatal sickle cell tests conform to the guidelines established by the American Congress of Obstetricians and Gynecologists and the American Academy of Pediatrics. METHODS:The project was initially structured as a pair of in-person interviews of postpartum wom...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,多中心研究
doi：10.1016/s0027-9684(15)30089-4
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:The purpose of this study is to characterize African-American women attending a community clinic who report frequent douching (douching > or = 2 times per week). METHODS:A consecutive sample of 115 black women attending a community clinic were interviewed face-to-face about their douching practices. Logistic...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:We conducted a cross-sectional study examining potentially modifiable factors associated with cognitive impairments (mild or severe) in older whites, African Americans and Hispanics attending an outpatient eye clinic. METHODS:In-clinic interviews and physical examinations assessed social, demographic and healt...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：:An analysis of the articles published in 1992 in the Journal of the National Medical Association (JNMA) was performed to assess the content, statistical analysis, and the profile of its contributors. Seventy-six articles were reviewed. The majority of the articles focused on biomedical aspects of health; however, a si...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:Ten cases of advanced squamous cell carcinoma of the skin in albinos, treated by radiotherapy from 1973 to 1979 at the Muhimbili Medical Center of Dar-es-Salaam, have been reviewed. Age, sex, duration of symptoms, anatomic distribution, stage of disease, and treatment are reviewed. The relationship between albinism, s...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1981-11-01 00:00:00
abstract：OBJECTIVE:We examined the relationship between frequency of incarceration and preincarceration risk behaviors and determined the demographic factors associated with risk behaviors among a sample of African American inmates. METHODS:We surveyed 229 (102 female and 127 male) randomly selected inmates. Risk behaviors bet...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30877-4
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Several studies have been published in the western literature on the incidence, clinical course and outcome of patients with ARDS. However, there is limited data about ARDS in the tropics and moreover, the etiology and outcomes of ARDS in tropical countries are different from those of western nations. In tro...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.07.002
更新日期：2018-08-01 00:00:00
abstract：:Underrepresented minorities (URMs) make up a disproportionately small percentage of medical school applicants, matriculants, and physicians relative to the general US population. Preprofessional pipeline programs may help introduce URMs to careers in the medical field. MiniMeds was developed as a paracurricular enrich...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30437-5
更新日期：2011-09-01 00:00:00
abstract：:Violence is now recognized as a health epidemic. Violence is especially prevalent in inner-city African-American communities. Most of the attention has focused on youths. However, the effects of violence extend to the communities' hypertensive patients. Patients are subjected to the emotional impact of violence on and...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND:Malnutrition, associated with poor outcome in the elderly, may be exacerbated by weight loss during hospitalization. Accurate estimation of energy requirements is important, particularly if predictions are applied to caloric supply. Because data on energy requirements for the elderly are limited, particularl...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:Pregnant women with sickle cell disease (SCD) are at increased risk of maternal and fetal complications. There are limited data on the outcome of the treatment of VOCs with opioids in relation to neonatal complications during pregnancy. METHODS:This is a retrospective cohort study of women with SCD from Jan...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.04.002
更新日期：2018-04-01 00:00:00
abstract：:Relatively high serum albumin levels compared to low levels have been associated with reduced cardiovascular mortality and coronary heart disease and stroke incidence. The nature of these associations remains undefined. Therefore, widely accepted criteria of Bradford Hill were used to assess the likelihood that the as...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:The case of a 43-year-old female with propylthiouracil-induced hepatitis is reported. The case is unique because the patient's liver function deteriorated 2 weeks after medication was discontinued. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:This study examined the clinical characteristics and outcome of pulmonary tuberculosis in African Americans hospitalized in a teaching hospital in south-central Los Angeles from May 1992 through April 1994. The charts of 41 African Americans with culture-positive Mycobacterium tuberculosis were reviewed. Predisposing ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1998-02-01 00:00:00
