Abstract：
BACKGROUND:It is commonly perceived that patients with sickle cell disease have increased hospital length of stay (LOS) because of mental health issues, including depression and drug-seeking behavior. However, the effect of mental and physical functional status on acute care resource use is unknown. OBJECTIVE:To assess Short Form (SF)-12 physical and mental health scores in adults with sickle cell disease and their impact on hospital LOS and costs. DESIGN:We identified 145 adults with sickle cell disease admitted to the general medicine ward at the University of Chicago Medical Center between July 1997 and June 2003. Seventy-nine patients (54%), with a total of 103 admissions, completed the SF-12 for at least one admission. Administrative data were used to obtain demographic information, LOS, and costs. Multivariate regression was used to measure the association between SF-12 physical and mental composite scores (by quartile), and LOS and costs. RESULTS:Twenty-five percent of patients accounted for nearly 80% of total hospital days and costs. The mean SF-12 physical score was 40 (SD, 12), and mental score 49 (SD, 12). Adjusted for age, gender, race, and comorbidities, admissions in the lowest quartile of the SF-12 physical composite score had an average LOS of 7.11 days and costs of $9060, compared to 4.6 days and $5520 in the highest quartile (p < .03, < .05). The SF-12 mental compositive score was not significantly associated with LOS or costs. CONCLUSIONS:Poor physical function rather than poor mental function independently predicts greater use of acute health care resources in adults with sickle cell disease.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Artz N,Zhang J,Meltzer Ddoi
10.1016/s0027-9684(15)30826-9subject
Has Abstractpub_date
2009-02-01 00:00:00pages
139-44issue
2eissn
0027-9684issn
1943-4693pii
S0027-9684(15)30826-9journal_volume
101pub_type
杂志文章abstract：INTRODUCTION:Black individuals continue to be underrepresented in clinical trials despite efforts by the National Institutes of Health and the Federal Drug Administration to increase their enrollment. Health care providers play a critical role in the recruitment of patients into clinical trials, as they have establishe...
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