Abstract：
:The three leukotriene (LT) modifiers approved for use in the United States, zileuton, zafirlukast, and montelukast, are the first new class of therapeutic agents to be introduced in 20 years for the treatment of asthma. These agents are referred to as leukotriene modifiers and have clearly demonstrated the ability to ameliorate bronchoconstriction and indices of airway edema and abnormal mucus production as observed in clinical trials. These agents have been shown to improve airflow, reduce the need for an inhaled bronchodilator, and improve nocturnal awakenings and asthma symptom scores appreciably. When combined with inhaled corticosteroid therapy, they may either provide additional improvement in efficacy or permit the reduction of the dose of inhaled corticosteroid necessary for effective therapy. Physicians should be familiar with these agents and consider them for use in their practice, in conjunction with current asthma management guidelines.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Valacer DJkeywords:
subject
Has Abstractpub_date
1999-08-01 00:00:00pages
26S-39Sissue
8 Suppleissn
0027-9684issn
1943-4693journal_volume
91pub_type
杂志文章,评审abstract：BACKGROUND:Although several studies have outlined the need for and benefits of diversity in academia, the number of underrepresented minority (URM) faculty in academic health centers remains low, and minority faculty are primarily concentrated at the rank of assistant professor. In order to increase the diversity of th...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:Small bowel obstruction, one of the most common causes of acute surgical abdomen in adults, constitutes approximately 20 percent of all cases of acute surgical abdomen. With improper management, strangulation of the bowel may occur and result in an increased probability of mortality. The author reviews the literature ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1981-03-01 00:00:00
abstract：:Case reports concerning rare complications of human bite injuries are uncommon in the literature. Further, rehabilitation of the resultant dysfunction is also hardly reported. A 41-year-old housewife who had had a human bite during an altercation 6 months ago was referred to the rehabilitation department with a nonfun...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30856-7
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:African American adults achieve smaller amounts of weight loss than their white counterparts when exposed to the same intervention and are more likely to regain weight during long-term follow-up. OBJECTIVE:To identify perceived motivators, barriers, and facilitators to weight loss and behavior change among ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.01.006
更新日期：2017-07-01 00:00:00
abstract：:The purpose of this study was to identify attitudes associated with the willingness of African Americans to participate in prostate cancer screening. Subjects > or = 40 years were recruited from South Central Los Angeles. Fifty-six respondents were divided into low or middle socioeconomic groups based on education and...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:This paper examines the previously studied topic of the prevalence of uncontrollable behavior in psychiatric emergencies, using the need for restraints as an indicator, and seeks to discover demographic characteristics that were associated with patients needing restraints. The variables considered are sex, referral so...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：:The surgical approach to liver injury depends on a clear and concise characterization of the wound. Blunt trauma can produce devastating wounds that disrupt hepatic venous drainage. Atrial caval shunting remains a useful technique for Grade V liver wounds. Liver packing may be necessary if diffuse lobar injury, acidos...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:COVID-19 is an emerging, rapidly evolving global situation, infecting over 25 million people and causing more than 850,000 deaths. Several signs and symptoms have been described to be characteristic of the disease. However, there is a dearth of report on the description of the clinical characteristics of t...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2020.11.011
更新日期：2020-12-22 00:00:00
abstract：:Early detection of pregnancy offers many advantages for the fetus and the mother. Many medical benefits depend on early detection, including social and emotional well-being and the aviodance of medicationss, irradiation, and other teratogencis. In the past, women became aware of their pregnancies only when organogen...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：:The objective of this study was to define the demographic, immunologic, and clinical characteristics of children with acquired immunodeficiency syndrome (AIDS) and AIDS nephropathy, and contrast this with the existing adult data. Data from 62 pediatric patients with AIDS who were treated at SUNY Health Science Center,...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:Many studies now demonstrate high overall response rates with concurrent chemotherapy and radiation (CCR) for locoregionally advanced or inoperable non-small cell lung carcinoma (NSCLC) but often with severe toxicity and only modest improvement in survival beyond 3 years. We report a simple CCR protocol for NSCLC that...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:Racial inequities in health continue to persist and one major controllable and preventable risk factor is obesity. This study examined whether psychosocial factors such as masculinity ideology and frequency of experiences with racism may be significantly associated with Black men's obesity risk. METHOD:Part...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.08.005
更新日期：2019-12-01 00:00:00
abstract：:A review of the literature on sickle cell trait was completed by Sears in 1978. Since that time, several papers have been published concerning the possible health risks of sickle cell trait. Data presented from these studies show that there is no association with sickle cell trait and overall survival, overall mortali...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1982-08-01 00:00:00
abstract：:The authors established the specificity, reliability, and precision of human erythrocyte insulin radioreceptor assay. On the basis of insulin binding, cell viability, and degree of hemolysis, heparin sodium was found to be a more suitable anticoagulant than sodium fluoride, ethylenediaminetetraacetic acid, sodium oxal...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-05-01 00:00:00
abstract：:Nosocomial sinusitis is occasionally overlooked as a source of sepsis in critically ill patients. Physical examination is usually unreliable and purulent nasal discharge is absent up to 73% of the time. Computed tomography scans of the sinuses and aspiration and culture of sinus fluid are the hallmark of diagnosis. Th...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1992-12-01 00:00:00
abstract：:This study explores the effects of abuse on the risk-taking behaviors of 2973 black and white adolescent males, 412 of whom were sexually or physically abused. Surveys on mental and physical health, risk-taking behaviors and attitudes, and family living were administered to 9th and 12th graders in an urban midwestern ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
abstract：:Surgery is the modality of choice in curative treatment for cancer of the colon and rectum. Since a majority of the patients present advanced disease where the surgical outlook is poor, adjuvant therapy may be warranted. Clinical and experimental data demonstrate the benefits from preoperative radiation therapy and so...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
abstract：:This report describes the treatment of a Viet Nam veteran with an α(2)-adrenergic agonist (clonidine) for hypertension which had an additional beneficial effect of allowing withdrawal in ten days from 20 mg of methadone a day with minimal withdrawal symptoms. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：PURPOSES:To assess patterns of dementia/Alzheimer's disease (AD) management and to investigate predictive factors of cholinesterase inhibitor prescriptions. METHODOLOGY:A cross-sectional study was conducted using a national survey among the elderly aged >60 from 2000 to 2002. Visit characteristics and cholinesterase i...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：:In the past 2 years, cities have reported skyrocketing rates of violence, crime, and abusive behavior including intrafamilial homicides. Of the 1838 homicide deaths last year among teenagers between the ages of 15 and 19, 71% involved the use of a firearm. Among black males in the same age group, 82% of the deaths wer...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:Polymastia is described and tumor formation in this condition is discussed. Two cases of carcinoma is aberrant breast tissue and one of fibroadenoma in a supernumerary breast are reported. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：OBJECTIVE:Minority populations have an increased risk for trauma, but little is known about injury rates for minority children. This study compares the causes, rates and outcomes of traumatic injuries between minority and white children in a statewide population sample. METHODS:A cohort study of 5,973 children (age <1...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2005-03-01 00:00:00
abstract：:Prehospital delay is an important cause of out-of-hospital coronary mortality. To determine the effects of decision time delay in a patient population comprised mainly of blacks and the underprivileged, 74 consecutive patients with acute chest pain necessitating admission to the coronary care unit in a large urban hos...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1993-03-01 00:00:00
abstract：:Few recent data are available from formal evaluations of approved new drug applications to address perceptions that racial and ethnic groups are under-represented in clinical trials of new drugs. This study reviews racial and ethnic group participation in clinical trials and race-related labeling for new molecular ent...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2001-12-01 00:00:00
abstract：:The number of satisfactory vascular organs suitable for organ transplantation can be increased appreciably by a close working relationship between traumatologists and transplant surgeons. Benefits will derive from more precise and rapid field management of brain-injured patients, with subsequent appropriate stabilizat...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:A day-long seminar was held at Wake Forest University School of Medicine to address barriers among ethnic minorities in cancer clinical trials and explore ways that individuals who design and conduct clinical trials could increase minority representation. Speakers addressed implications of under-representation of mino...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Several studies have been published in the western literature on the incidence, clinical course and outcome of patients with ARDS. However, there is limited data about ARDS in the tropics and moreover, the etiology and outcomes of ARDS in tropical countries are different from those of western nations. In tro...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2017.07.002
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:This study examined gender differences in how three social roles - marriage, parenthood, and employment - impact depressive symptoms and clinically significant depression for African Americans in the first decade of midlife, from 40 to 50 years old. Specifically, we sought to understand the associations betwe...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2018.10.012
更新日期：2019-06-01 00:00:00
abstract：:Victims of domestic violence appeal to the health care system through emergency room visits for injuries related to violent episodes or for proxy care for other complaints. Screening for persons who are at high risk for violence or who are victims of violence has not been performed in emergency rooms when patients pre...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：:A 75-year-old woman with two previous neck operations for follicular carcinoma of the thyroid presented with a breast mass nine years after diagnosis. The mass recurred one month after excisional biopsy. Pathological examination revealed metastatic follicular carcinoma. The breast tumor was weakly positive for estroge...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-11-01 00:00:00
