Abstract：
OBJECTIVE:We aimed to prospectively examine the relationship between vision and hearing loss and successful aging in a cohort of older adults. STUDY DESIGN:We analyzed 5-year data (1997-9 to 2002-4) from 1,085 adults aged 55+ years, who were free of cancer, coronary artery disease and stroke at baseline and who had complete data on sensory loss. MAIN OUTCOME MEASURES:Visual impairment was defined as visual acuity <20/40 (better eye), and hearing impairment as average pure-tone air conduction threshold >25 dBHL (500-4000 Hz, better ear). Successful aging was defined as the absence of: disability, depressive symptoms, cognitive impairment, respiratory symptoms and chronic diseases (cancer, coronary artery disease and stroke) at 5-year follow-up. RESULTS:At 5-year follow-up, 243 (22.4%) participants had died and 248 (22.9%) had aged successfully. After multivariable adjustment, participants who had either best-corrected visual impairment or bilateral hearing impairment, versus those who did not have sensory impairment at baseline, had 37% reduced odds of successful aging after 5 years: OR 0.63 (95% CI 0.43-0.94). Concurrent vision and hearing loss at baseline was not associated with 5-year aging status. Participants with moderate and severe hearing handicap at baseline had 50% and 61% reduced odds of aging successfully after 5 years, respectively. CONCLUSION:The presence of a single sensory impairment in older adults was associated with reduced odds of being disease-free and fully functional or having aged successfully, 5 years later. Objectively measured hearing loss and self-perceived hearing handicap, rather than vision loss, was more likely to negatively influence 5-year aging status.
journal_name
Maturitasjournal_title
Maturitasauthors
Gopinath B,Liew G,Burlutsky G,McMahon CM,Mitchell Pdoi
10.1016/j.maturitas.2020.10.015subject
Has Abstractpub_date
2021-01-01 00:00:00pages
203-208eissn
0378-5122issn
1873-4111pii
S0378-5122(20)30415-1journal_volume
143pub_type
杂志文章相关文献
MATURITAS文献大全abstract：:Insomnia, vasomotor symptoms (VMS) and depression often co-occur after the menopause, with consequent health problems and reductions in quality of life. The aim of this position statement is to provide evidence-based advice on the management of postmenopausal sleep disorders derived from a systematic review of the lit...
journal_title：Maturitas
pub_type： 杂志文章,实务指引
doi：10.1016/j.maturitas.2019.08.006
更新日期：2019-11-01 00:00:00
abstract：:In a population-based prospective study it was shown that weight, height, overweight, total body size, age at first birth, parity and age at menopause are risk factors for the development of endometrial cancer. The finding that the patients had had a higher oestrogen excretion level than the controls some time before ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(85)90036-2
更新日期：1985-05-01 00:00:00
abstract：:Cardiovascular disease is the leading cause of death in women throughout the United States and Europe. Despite efforts to raise awareness, the sex-specific risk factors are still poorly recognized in both regions, and many women do not identify cardiovascular disease as a primary threat. During midlife, the incidence ...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2018.11.004
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To study whether dose adjustments in transdermal estradiol gel treatment would result in proportional changes in estradiol bioavailability and concentrations. METHODS:In an open study, 23 healthy postmenopausal women were treated consecutively with 0.5, 1.0 and 1.5 mg estradiol daily as a transdermal gel. E...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(00)00101-8
更新日期：2000-04-28 00:00:00
abstract：:This study investigated the effect of ageing and reduction in ovarian function on whole blood serotonin levels and the effect of the oestrogen replacement in postmenopausal women on blood serotonin levels. Amenorrheic, natural postmenopausal and ovariectomised women had lower blood serotonin levels than regularly mens...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(93)90120-7
更新日期：1993-07-01 00:00:00
abstract：:A review of how the anthropologist has studied the menopause, the climacteric and middle age is given. The types of field methodology used by the anthropologist in the above-mentioned studies are described, and their application for research in other fields is suggested. Research problems which have yet to be addresse...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(82)90047-0
更新日期：1982-11-01 00:00:00
abstract：OBJECTIVE:The present study was undertaken to assess the impact, effectiveness and safety of a monophasic hormone replacement treatment (HRT) for continuous use with regards to the clinical effects, bleeding patterns and lipid profile of menopausal women in four Latin American countries. DESIGN:Three hundred and six p...
journal_title：Maturitas
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.maturitas.2004.05.014
更新日期：2005-03-14 00:00:00
abstract：:Menopause is a time of anatomic, physiological and psychological changes that often influence in the sexuality of aging female. Being sexual functioning an important aspect of health and well-being, doctors should have an holistic approach reassuring about the possibility of treating the various symptoms. The central ...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/s0378-5122(02)00150-0
更新日期：2002-08-30 00:00:00
abstract：OBJECTIVES:To compare the metabolic and endocrinological effects of estradiol valerate/cyproterone acetate (EV/CPA) to a regimen of conjugated estrogens/medroxyprogesterone acetate (CE/MPA) in postmenopausal women. METHODS:Lipid profile, endocrinological parameters, coagulation factors, renin and angiotensinogen were ...
journal_title：Maturitas
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0378-5122(97)00042-x
更新日期：1997-07-01 00:00:00
abstract：:In order to assess the possible role of circulating immunoreactive inhibin (INH) during the menopausal transition, two groups of subjects were studied. Four were normal volunteers, three of whom had developed their first symptoms of cycle irregularity at age 45-46 years, the fourth being aged 37, a volunteer for a stu...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(93)90026-e
更新日期：1993-12-01 00:00:00
abstract：:The immune system plays an essential role in the tumor progression; not only can it inhibit tumor growth but it can also promote tumor growth by establishing a favorable environment. Tumor cells utilize several strategies to evade the host's immune system, including expression of immunosuppressive molecules such as PD...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2017.04.014
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVES:The aim of this study is to determine if the depression in perimenopausal women is symptomatologically different than depression in premenopausal women, and if these depressive women are under more risk for depression when factors like premenstrual dysphoric syndrome, socio-economical status, vasomotor sympt...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2006.02.001
更新日期：2006-09-20 00:00:00
abstract：:The effect of two forms of exogenous estrogen and a placebo on diastolic blood pressure and bodyweight was evaluated in 50 oophorectomized women. There was no significant change in bodyweight on any form of treatment, nor was there any significant elevation in mean diastolic blood pressure. However, 2 out of 49 female...
journal_title：Maturitas
pub_type： 临床试验,杂志文章
doi：10.1016/0378-5122(78)90003-8
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVE:To compare clinical characteristics and management of adnexal torsion in postmenopausal patients as compared to premenopausal ones. METHODS:A retrospective 22 year cohort of all cases of surgically verified adnexal torsion in postmenopausal and premenopausal patients, comparing presentation, imaging, surgica...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2015.02.261
更新日期：2015-05-01 00:00:00
abstract：:We audited the files of 114 postmenopausal women who had been treated with subcutaneous Estrapel (50mg oestradiol implants). Of the 92 women who received more than one implant, the median number of days between implants was 223.5 (range 49-875), with an estimated median time to return to baseline of 311days (range 108...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2016.09.008
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to determine the relationships of serum estrogen levels after hormone replacement therapy (HRT) every other day and every day with body mass index (BMI) in postmenopausal and bilaterally ovariectomized women. METHODS:Eighty-six postmenopausal and 51 bilaterally ovariectomized ...
journal_title：Maturitas
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.maturitas.2004.03.013
更新日期：2005-01-10 00:00:00
abstract：:The effect of estradiol valerate (Progynova, 2 mg daily) on the renin--aldosterone system was studied in nine women after bilateral oophorectomy. Plasma renin activity (PRA) and the daily urinary excretion of aldosterone (dU-Ald) were determined 4 mth after the operation -- during which no estrogen was given -- and af...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(80)90041-9
更新日期：1980-07-01 00:00:00
abstract：:Earlier menopause onset has been linked to a greater risk of cardiovascular disease. Both menopause onset and cardiovascular disease risk vary by geographical region, race/ethnicity and socioeconomic status. As such, it is plausible to hypothesize that these factors may influence the association of menopause onset and...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2020.06.007
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Quality of life decreases after the menopause as it has been assessed by several designed tools. Despite this, few studies have reported correlations between quality of life and the metabolic syndrome and its determinants. OBJECTIVE:Evaluate quality of life and determine factors related to its impairment am...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2006.05.008
更新日期：2007-01-20 00:00:00
abstract：:Vitamin D, a soluble steroid hormone synthesized in the skin after sun exposure, plays a crucial role in calcium metabolism and is also involved in cardiovascular pathophysiology. The aim of this review is to summarize the available evidence (a) on the association between endogenous vitamin D status and cardiovascular...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2018.05.010
更新日期：2018-09-01 00:00:00
abstract：INTRODUCTION:Osteoporosis and its consequent fractures is a major public health problem. AIM:To formulate a position statement on the use of bone densitometry in screening postmenopausal women for osteoporosis and in their management. MATERIALS AND METHODS:Literature review and consensus of expert opinion. RESULTS A...
journal_title：Maturitas
pub_type： 杂志文章,实务指引
doi：10.1016/j.maturitas.2010.09.009
更新日期：2011-01-01 00:00:00
abstract：:Worldwide, the number of menopausal women is increasing. They present with complex medical issues that lie beyond the traditional scope of gynaecologists and general practitioners (GPs). The European Menopause and Andropause Society (EMAS) therefore provides a holistic model of care for healthy menopause (HM). The HM ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2016.06.018
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVES:To examine the association between the principal lifetime occupation and the incidence of Alzheimer's disease (AD) in men and women in a southern European population aged 55 years or more. STUDY DESIGN:A community-dwelling sample of 3883 dementia-free individuals aged 55 years or over was classified accordi...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2019.05.008
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:Decision-making during menopause (especially surgical menopause) can be complex given the variability in risk-benefit perceptions of menopausal treatments. Decision aid tools (DATs) help women participate in decision-making about options. Our objective is to identify and evaluate the content and development o...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2017.09.006
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVES:Association studies between estrogen receptor alpha (ERalpha) gene polymorphisms and bone mineral density (BMD) have yielded inconsistent results. In the present study we evaluated the influence of XbaI and PvuII ERalpha gene polymorphisms on BMD, biochemical markers, rates of bone loss and the response to e...
journal_title：Maturitas
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.maturitas.2005.07.007
更新日期：2006-03-20 00:00:00
abstract：OBJECTIVE:Alterations in sleep quality and metabolism during menopause are improved by menopausal hormone therapy (MHT). The mechanisms mediating these effects remain unclear. Orexin A (OxA) is a neuro-peptide that regulates sleep/wakefulness, food intake and metabolism. This study examined changes in plasma OxA levels...
journal_title：Maturitas
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.maturitas.2017.01.016
更新日期：2017-05-01 00:00:00
abstract：:Estrogen is a well-known mitogen in human breast epithelium but the action of progestogen is complex and incompletely understood. During the last years, accumulating data from animal, clinical and observational studies suggest a proliferative effect in breast tissue when progestogen is added to estrogen. Findings in s...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2004.06.008
更新日期：2004-09-24 00:00:00
abstract：OBJECTIVES:Our pilot study tested the efficacy, acceptability and tolerability of DHA supplementation in addition to calcium and vitamin D in individuals with osteopenia. STUDY DESIGN:40 participants were randomised to either algal oil containing 400mg docosahexanoic acid (DHA) daily or placebo. All participants recei...
journal_title：Maturitas
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.maturitas.2011.10.004
更新日期：2012-01-01 00:00:00
abstract：:Two case reports of women treated with an individual cognitive behavioral treatment (CBT) for menopausal hot flashes are presented. Both women reported substantial improvements in the number of hot flashes experienced as well as in their quality of life as measured by the Menopause Quality of Life Scale (MENQOL), the ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2005.12.006
更新日期：2006-04-20 00:00:00
abstract：AIM:The aim was to investigate bone mineral density (BMD) in breast cancer patients with positive estrogen receptor (ER) tumor status. METHODS:The participants were 110 postmenopausal breast cancer patients with positive estrogen receptor (ER+) tumor status. Two hundred and sixty-one age-matched, healthy postmenopausa...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2006.11.012
更新日期：2007-07-20 00:00:00
