Abstract:
:Menopause is a time of anatomic, physiological and psychological changes that often influence in the sexuality of aging female. Being sexual functioning an important aspect of health and well-being, doctors should have an holistic approach reassuring about the possibility of treating the various symptoms. The central nervous system is an important target for sex steroid hormone; estrogen, progestagens and androgens are able to modulate several brain functions, and receptors for gonadal steroids have been identified in several brain areas. Because there is no test that physicians can make to assess sexual function, taking a sexual history is probably the most important aspect in the diagnostic and treatment of sexual problems. Hormonal transition with decreasing levels of estrogen and testosterone produces clinical effects, so women need to make adjustments for this period of life. Testosterone is an important component of female sexuality, and alterations in its circulating levels play an important role in psychological and sexual changes that occur after menopause. This is the reason why the research in identifying women who have a decrease androgen active should be aimed. Treatment may include education about sexuality and medical management of symptoms or problems interfering with sexual activity. Also treatment implications and the diverse aspects that may influence on sexuality in the climacteric years are discussed.
journal_name
Maturitasjournal_title
Maturitasauthors
Palacios S,Tobar AC,Menendez Cdoi
10.1016/s0378-5122(02)00150-0keywords:
subject
Has Abstractpub_date
2002-08-30 00:00:00pages
S69-77eissn
0378-5122issn
1873-4111pii
S0378512202001500journal_volume
43 Suppl 1pub_type
杂志文章,评审相关文献
MATURITAS文献大全abstract::We audited the files of 114 postmenopausal women who had been treated with subcutaneous Estrapel (50mg oestradiol implants). Of the 92 women who received more than one implant, the median number of days between implants was 223.5 (range 49-875), with an estimated median time to return to baseline of 311days (range 108...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2016.09.008
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:Aging is associated with changes in resting energy expenditure (REE) and body composition. We investigated the association between age and changes in REE in men and women stratified by body mass index (BMI) categories (normal weight, overweight and obesity). We also examined whether the age-related decline i...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2014.12.023
更新日期:2015-04-01 00:00:00
abstract::The incidence of breast cancer has continued to decrease each year at Wilford Hall United States Air Force Medical Center with the ever-increasing use of combined progestogen-oestrogen replacement therapy over the past 12 yr. By 1983, the overall incidence of breast cancer had fallen to 53.9:100 000. The lowest rate f...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(86)90023-x
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVES:The effects of supplemental testosterone on cognition, mood and wellbeing in ageing men are unclear. This study aimed to assess the effect of 12-months of oral testosterone supplementation on cognitive function, mood and quality of life in elderly men with low-normal gonadal status, not specifically selected...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.maturitas.2004.05.002
更新日期:2005-02-14 00:00:00
abstract::In the present study, unopposed oestrogens were given to 184 non-hysterectomized women, for a duration varying from four weeks to 24 months, while the endometrial responses were monitored by transvaginal sonography (TVS) and backed up by endometrial sampling (conducted when the endometrial thickness reached 8 mm (doub...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(96)00995-4
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to search the effects of two different doses of tibolone on endometrial IGF-1 and IGFBP-1 levels in ovariectomized rats. METHODS:Eighteen adult, female, 80-90-days-old, Wistar rats with an average weight of 250 g underwent bilateral ovariectomy under general anesthesia. After waiti...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(02)00068-3
更新日期:2002-07-25 00:00:00
abstract:OBJECTIVE:To assess the symptomatology of menopause and the use of hormone therapy among women in Spain. METHODS:A survey conducted on a representative sample of 300 women aged 45-55 in Madrid. The instrument included closed- and open-ended questions about demographic and socio-economic information, health and reprodu...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2005.01.011
更新日期:2005-11-01 00:00:00
abstract::Five men and 8 women, 60-69 yr of age, and 4 men and 5 women, 17-37 yr of age, volunteered for this exploration of possible age-related changes in circadian-rhythm (CR) characteristics of radioimmunoassayable plasma renin (PRA) and aldosterone (PA). Blood was drawn at 06.00, 08.00, 12.00, 18.00, 20.00 and 24.00 from r...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(81)90009-8
更新日期:1981-08-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the frequency with which hormone replacement therapy (HRT) was prescribed and to identify physician-related factors associated with the prescription of HRT in Spain. STUDY DESIGN:A descriptive cross-sectional survey based on a personal interview with a structured q...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2006.04.023
更新日期:2006-11-20 00:00:00
abstract::Peyronie's disease is an incurable, sexually debilitating fibrotic disease of the penis that results in penile curvature, coital failure, and significant psychological stress for patients and their partners. Appropriate treatment should be individualized and tailored to the patient's goals and expectations, disease hi...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2014.05.024
更新日期:2014-08-01 00:00:00
abstract::Dementia has often thought to be unavoidable and incurable. In recent years, risk factors, including lifestyle attributes, have been associated with the two commonest forms of dementia, Alzheimer's Disease and vascular dementia. There is also new evidence that the adult brain maintains plasticity and response to exter...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2009.06.008
更新日期:2009-08-20 00:00:00
abstract:OBJECTIVES:Association studies between estrogen receptor alpha (ERalpha) gene polymorphisms and bone mineral density (BMD) have yielded inconsistent results. In the present study we evaluated the influence of XbaI and PvuII ERalpha gene polymorphisms on BMD, biochemical markers, rates of bone loss and the response to e...
journal_title:Maturitas
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.maturitas.2005.07.007
更新日期:2006-03-20 00:00:00
abstract::Since the launch in 2008 by the National Osteoporosis Guideline Group (NOGG), of guidance for the diagnosis and management of osteoporosis in postmenopausal women and older men in the UK there have been significant advances in risk assessment and treatment. These have been incorporated into an updated version of the g...
journal_title:Maturitas
pub_type: 杂志文章,实务指引
doi:10.1016/j.maturitas.2013.05.013
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Participation in regular physical activity is among the most promising and cost effective strategies to reduce physical and cognitive decline and premature death. However, confusion remains about the amount, frequency, and duration of physical activity that is likely to provide maximum benefit as well as the...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2014.06.010
更新日期:2014-09-01 00:00:00
abstract::The explanations so far proposed for the effects of oestrogens on bone metabolism in post-menopausal women have been based on the changes seen in calciotrophic hormones. However, we demonstrated in a previous study [6] that there is a decrease in the concentration of somatomedin (an insulin-like growth factor) and an ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(86)90002-2
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVES:Our pilot study tested the efficacy, acceptability and tolerability of DHA supplementation in addition to calcium and vitamin D in individuals with osteopenia. STUDY DESIGN:40 participants were randomised to either algal oil containing 400mg docosahexanoic acid (DHA) daily or placebo. All participants recei...
journal_title:Maturitas
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.maturitas.2011.10.004
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To evaluate changes in mammographic density and (99m)Tc-sestamibi scintimammographic uptake in postmenopausal women on hormone replacement therapy (HRT). METHODS:Seventy-five postmenopausal women were prospectively studied and allocated into three groups: 50 women were randomized to either Group 1 (G1, n=25)...
journal_title:Maturitas
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.maturitas.2005.03.016
更新日期:2006-01-10 00:00:00
abstract:OBJECTIVE:To evaluate the pharmacodynamic effects of a novel intrauterine drug delivery system, FibroPlant-levonorgestrel (LNG), on the endometrium in 24 postmenopausal women using estrogen substitution therapy (EST) to suppress climacteric symptoms. DESIGN:A 3-year non-comparative prospective clinical trial. SUBJECT...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2003.07.002
更新日期:2004-05-28 00:00:00
abstract:OBJECTIVE:Aging and menopause are associated with an adverse cardiometabolic profile, predisposing to cardiovascular disease. Diet may also affect their cardiometabolic risk. The aim of this study is to assess dietary habits and patterns of postmenopausal women and their association with adiposity measures, cardiometab...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2018.07.006
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Health-related quality of life (HRQoL) provides an accurate measure of the health status of patients with coronary heart disease (CHD). However, few studies have examined the relationship between physical inactivity and HRQoL in CHD survivors. We evaluated this association in a cross-sectional study of 21,93...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2019.07.005
更新日期:2019-10-01 00:00:00
abstract::Dementia affects approximately 6.5% of people over the age of 65. Whilst cognitive impairment is central to the dementia concept, neuropsychiatric symptoms are invariably present at some stage of the illness. Neuropsychiatric symptoms result in a number of negative outcomes for the individual and their caregivers and ...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2014.04.005
更新日期:2014-10-01 00:00:00
abstract::As increasing numbers of individuals reach very advanced age, it is important to understand the influence of modifiable lifestyle factors such as diet and nutrition on both the achievement of exceptional longevity as well as the maintenance of optimal functional capacity. This includes determining the most appropriate...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2011.12.002
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To determine the changes in levels of urinary NTx at the end of the 6th month of oral and transdermal hormone replacement therapy (HRT) and the effects of additional alendronate therapy for osteoporotic women. METHOD:Of 66 postmenopausal women 23 were treated with oral estradiol+norethisterone acetate (E+P),...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(02)00156-1
更新日期:2002-08-30 00:00:00
abstract:OBJECTIVES:The current study investigated the neurotrophic and neuroprotective action of the complex formulation of conjugated equine estrogens (CEEs), the most frequently prescribed estrogen replacement therapy in the United States and the estrogen replacement therapy of the Women's Health Initiative. METHODS:Videomi...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(00)00107-9
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVES:To assess the prevalence of climacteric symptoms and the use of hormone replacement therapy in a former eastern European country. All 55-, 57-, 59- and 61-year-old women in Kladno in the Czech Republic were asked to participate in the study. METHOD:In 1993, 1505 women in Kladno of the Czech Republic were se...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(95)00965-5
更新日期:1996-02-01 00:00:00
abstract::It is important for our aging population to remain active, particularly those with chronic diseases, like Parkinson disease (PD), which limit mobility. Recent studies in older adults and people with PD suggest dance interventions provide various motor benefits. The literature for dance in PD is growing, but many knowl...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2015.02.007
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:The present study was undertaken to assess the impact, effectiveness and safety of a monophasic hormone replacement treatment (HRT) for continuous use with regards to the clinical effects, bleeding patterns and lipid profile of menopausal women in four Latin American countries. DESIGN:Three hundred and six p...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.maturitas.2004.05.014
更新日期:2005-03-14 00:00:00
abstract:BACKGROUND:Increased frequency and severity of menopausal symptoms have been associated to black race. However, this situation has not been described in any Latin American population. OBJECTIVE:Compare frequency and severity of menopausal symptoms among Afro and non-Afro Hispanic Colombian climacteric women. METHODS:...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2007.12.002
更新日期:2008-02-20 00:00:00
abstract:OBJECTIVES:This paper examines the evidence supporting testosterone replacement in aging males. Confounding factors contributing to low testosterone levels and challenges to diagnosis of the andropause will also be considered. METHODS:A thorough review using an integrative approach citing published literature and the ...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/s0378-5122(03)00083-5
更新日期:2003-05-30 00:00:00
abstract::International, national and regional policy documents and key reports espouse the benefits of lifelong learning and people's rights to it, yet little attention has been given to the learning needs of frail older people in nursing (care) homes. People living in care have frequently been cited as a forgotten sector of t...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2020.05.019
更新日期:2020-10-01 00:00:00