Abstract：
:The explanations so far proposed for the effects of oestrogens on bone metabolism in post-menopausal women have been based on the changes seen in calciotrophic hormones. However, we demonstrated in a previous study [6] that there is a decrease in the concentration of somatomedin (an insulin-like growth factor) and an increase in that of growth hormone (GH) in oestrogen-treated post-menopausal women. On the basis of those findings and the relevant data published in the literature, we advance a hypothesis to the effect that the bone-metabolism changes that occur in post-menopausal women following oestrogen replacement therapy come about via changes in serum somatomedin and growth hormone concentrations.
journal_name
Maturitasjournal_title
Maturitasauthors
Duursma SA,Bijlsma JW,van Paassen HC,Slootweg MCdoi
10.1016/0378-5122(86)90002-2subject
Has Abstractpub_date
1986-03-01 00:00:00pages
1-6issue
1eissn
0378-5122issn
1873-4111pii
0378-5122(86)90002-2journal_volume
8pub_type
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