Endometrial safety with a low-dose intrauterine levonorgestrel-releasing system after 3 years of estrogen substitution therapy.

abstract：OBJECTIVES:To assess the prevalence of climacteric symptoms and the use of hormone replacement therapy in a former eastern European country. All 55-, 57-, 59- and 61-year-old women in Kladno in the Czech Republic were asked to participate in the study. METHOD:In 1993, 1505 women in Kladno of the Czech Republic were se...

journal_title：Maturitas

authors： Nedstrand E,Pertl J,Hammar M

更新日期：1996-02-01 00:00:00

abstract：:Plasma androstenedione (A) and oestrone (E1) levels were measured by radioimmunoassay in a group of 78 healthy women who had undergone a natural menopause. Of this total, 23 were symptomless (Group 1), 39 presented with a moderate climacteric syndrome (Group 2) and 16 had a severe climacteric syndrome (Group 3). The a...

journal_title：Maturitas

authors： Mango D,Scirpa P,Battaglia F,Bini E

更新日期：1984-04-01 00:00:00

abstract：:While low back pain significantly impacts on an individual's well-being, our understanding of the role of well-being in the natural history of low back pain is limited. This cohort study aimed to investigate the association between psychological and general well-being and the development and progression of low back pa...

journal_title：Maturitas

authors： Ng SK,Cicuttini FM,Davis SR,Bell R,Botlero R,Fitzgibbon BM,Urquhart DM

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:The complexity of care required by many older people living in long-term care (LTC) facilities poses challenges that can lead to potentially avoidable referrals to a hospital emergency department (ED). The Aged Residential Care Intervention Project (ARCHIP) ran an implementation study to evaluate a multidi...

journal_title：Maturitas

authors： Connolly MJ,Broad JB,Bish T,Zhang X,Bramley D,Kerse N,Bloomfield K,Boyd M

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The present study was undertaken to assess the impact, effectiveness and safety of a monophasic hormone replacement treatment (HRT) for continuous use with regards to the clinical effects, bleeding patterns and lipid profile of menopausal women in four Latin American countries. DESIGN:Three hundred and six p...

journal_title：Maturitas

authors： Bassol S,Carranza-Lira S,Celis-Gonzalez C,Santoyo S,Murillo A,Martinez N,Santos J,Llaca V,de la Loza FR,Zarain J,da Fonseca AM,Camargos AF,Baracat EC,da Sá MF,Bayo J,Adaro L,Gurucharri C,Murga M,Siseles N,Sayegh F,

更新日期：2005-03-14 00:00:00

abstract：:Within the last decade, breast cancer is increasingly understood as a heterogeneous disease comprising distinct entities that vary significantly with regard to molecular biology and clinical features. Despite impressive advances in the treatment of patients with breast cancer, not all patients derive equal benefits fr...

journal_title：Maturitas

authors： Liedtke C,Kiesel L

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:To establish dose proportionality among four doses of a new estradiol transdermal system (ETS), Estradot, in healthy postmenopausal women and to evaluate the wear and irritation properties of the ETS. METHODS:In an open label, single-dose, randomized, four-period crossover study, healthy postmenopausal wome...

journal_title：Maturitas

authors： Hossain M,Quebe-Fehling E,Sergejew T,Schmidt G,Skerjanec A,Ibarra de Palacios P,Krinsky L

更新日期：2003-11-20 00:00:00

abstract：OBJECTIVES:This paper aims to report the methodology of a study of a cohort of middle-aged women in Taiwan, their age at menopause, and related factors and prevalence of menopausal symptoms, and to examine the relationships between symptoms and sociodemographic variables. METHODS:An epidemiological study of neuropsych...

journal_title：Maturitas

authors： Fuh JL,Wang SJ,Lu SR,Juang KD,Chiu LM

更新日期：2001-08-25 00:00:00

abstract：:Ageing populations represent a challenge to the sustainability of current healthcare systems. The need to balance these demographic changes with gains in healthy life years and quality of life (QoL) constitutes an additional challenge. Aware of this, the European Commission (EC) launched the European Innovation Partne...

journal_title：Maturitas

authors： Cano A,Dargent G,Carriazo A,López-Samaniego L,Apostolo J,Campos E,Holland C,Varela-Nieto I,Luz Sánchez-Sánchez M,Illario M,Iaccarino G,Roller RE,Goossens E,Vollenbroek-Hutten M,Pais S,Schena F,Musian D,Alvino S,Maggio

更新日期：2018-09-01 00:00:00

abstract：:Globally our populations are ageing and with this trend, there is a rise in chronic disease. We know that lifestyle and environment are significant contributors to risk for disease, quality of life and function. Despite this representing an opportunity to improve health and quality of life in ageing, there is a paucit...

journal_title：Maturitas

authors： Campbell S,Burn K,Szoeke C

更新日期：2016-10-01 00:00:00

abstract：:In the present study, unopposed oestrogens were given to 184 non-hysterectomized women, for a duration varying from four weeks to 24 months, while the endometrial responses were monitored by transvaginal sonography (TVS) and backed up by endometrial sampling (conducted when the endometrial thickness reached 8 mm (doub...

journal_title：Maturitas

authors： Meuwissen JH,Oddens BJ,Klinkhamer PJ

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To clarify the effect of programmed exercise (PE), performed for at least six weeks, on perceived stress (PS) in middle aged and old women. METHODS:A structured search was carried out in PubMed, Embase, Cochrane Library, Scielo, Web of Science and Scopus, from database inception through January 10, 2018, wit...

journal_title：Maturitas

authors： Nigdelis MP,Martínez-Domínguez SJ,Goulis DG,Pérez-López FR

更新日期：2018-08-01 00:00:00

abstract：:The objective of this systematic review and meta-analysis was to evaluate the efficacy and the effectiveness, as well as the safety and tolerability, of urethral bulking agents (UBAs) in women with mixed or stress urinary incontinence. PubMed, Scopus, and the Cochrane Central Register of Controlled Trials were used to...

journal_title：Maturitas

authors： Capobianco G,Saderi L,Dessole F,Petrillo M,Dessole M,Piana A,Cherchi PL,Dessole S,Sotgiu G

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:To determine the median age of natural menopause in United Arab Emirates women, the factors affecting that age and the prevalence of climacteric symptoms amongst those women. METHODS:A population-based survey was conducted on a community sample of United Arab Emirates women who had had natural menopause def...

journal_title：Maturitas

authors： Rizk DE,Bener A,Ezimokhai M,Hassan MY,Micallef R

更新日期：1998-06-17 00:00:00

abstract：:To prevent hyperplasia and carcinoma of the endometrium during oestrogen replacement therapy (ORT), the addition of progestogens once a month is considered mandatory. However, there is no sound scientific basis for this assumption. As the addition of progestogens has several disadvantages, it is important to minimize ...

journal_title：Maturitas

authors： Meuwissen JH,van Langen H,Moret E,Navarro-Morquecho I

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:We aimed to prospectively examine the relationship between vision and hearing loss and successful aging in a cohort of older adults. STUDY DESIGN:We analyzed 5-year data (1997-9 to 2002-4) from 1,085 adults aged 55+ years, who were free of cancer, coronary artery disease and stroke at baseline and who had co...

journal_title：Maturitas

authors： Gopinath B,Liew G,Burlutsky G,McMahon CM,Mitchell P

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To compare the influence on lipid metabolism of two discontinuous, sequentially combined hormone replacement therapy (HRT) regimens. STUDY DESIGN:In an open, randomized study in 60 women, a full lipid profile including Lp(a) and liver function tests were assessed in a fasting state at the end of treatment cy...

journal_title：Maturitas

authors： Schram JH,Boerrigter PJ,The TY

更新日期：1995-09-01 00:00:00

abstract：:Ageing of human skin may result from both the passage of time (intrinsic ageing) and from cumulative exposure to external influences (extrinsic ageing) such as ultraviolet radiation (UVR) which promote wrinkle formation and loss of tissue elasticity. Whilst both ageing processes are associated with phenotypic changes ...

journal_title：Maturitas

authors： Naylor EC,Watson RE,Sherratt MJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:It is still controversial whether hormone replacement therapy (HRT) can affect the onset of uterine myomas or their growth in postmenopause. It is likely that some therapeutic schedules can influence the myometrial growth differently, due to a more potent stimulation of the uterine receptors. The aim of the ...

journal_title：Maturitas

authors： Polatti F,Viazzo F,Colleoni R,Nappi RE

更新日期：2000-11-30 00:00:00

abstract：OBJECTIVE:To study the possible changes in serum lipids and lipoproteins during hormone replacement therapy with special emphasis on the possible effects brought about by the progestogen. DESIGN:Open-label randomized prospective comparative study. SETTING:Gynecological outpatient department of an university hospital....

journal_title：Maturitas

authors： van der Mooren MJ,Leuven JA,Rolland R

更新日期：1994-05-01 00:00:00

abstract：:Associations between depression and impaired functioning are well known and have been documented in numerous clinical, primary care and epidemiological studies. Reviews of this research have focused on the elderly. Recent studies suggest that women become increasingly vulnerable during the menopausal transition to dec...

journal_title：Maturitas

authors： Bromberger JT,di Scalea TL

更新日期：2009-11-20 00:00:00

abstract：OBJECTIVE:To determine whether individually tailored acupuncture is an effective treatment option for reducing postmenopausal hot flashes and improving quality of life. METHODS:In a randomized, placebo-controlled pilot study, 29 postmenopausal participants averaging at least seven moderate to severe hot flashes per 24...

journal_title：Maturitas

authors： Nir Y,Huang MI,Schnyer R,Chen B,Manber R

更新日期：2007-04-20 00:00:00

abstract：OBJECTIVE:Deficiency of the gene encoding endothelial nitric oxide synthase, i.e. Nos3, has been reported to be associated with late menarche, reduced ovulation rates, fewer deliveries, and earlier onset of menopause in a mouse model. METHODS:We assessed the Glu298Asp and the T-786C polymorphisms of Nos3 in 87 consecu...

journal_title：Maturitas

authors： Worda C,Walch K,Sator M,Eppel W,Tempfer CB,Schneeberger C,Huber JC,Hefler LA

更新日期：2004-10-15 00:00:00

abstract：:It is important for our aging population to remain active, particularly those with chronic diseases, like Parkinson disease (PD), which limit mobility. Recent studies in older adults and people with PD suggest dance interventions provide various motor benefits. The literature for dance in PD is growing, but many knowl...

journal_title：Maturitas

authors： McNeely ME,Duncan RP,Earhart GM

更新日期：2015-05-01 00:00:00

abstract：:Examining such terms as climacteric or menopause and utilizing supportive historical data, an attempt is made to trace the development of these concepts, their time of inception and their spread. It is suggested that the persistence of popular terminology of the climacteric, especially in England, until late in the la...

journal_title：Maturitas

authors： Wilbush J

更新日期：1981-03-01 00:00:00

abstract：:The synthetic progestins used so far for contraception and menopausal hormone therapy are derived either from testosterone (19-nortestosterone derivatives) or from progesterone (17-OH progesterone derivatives and 19-norprogesterone derivatives). Among the 19-nortestosterone derivatives, the estrane group include noret...

journal_title：Maturitas

authors： Sitruk-Ware R

更新日期：2004-04-15 00:00:00

abstract：:Two case reports of women treated with an individual cognitive behavioral treatment (CBT) for menopausal hot flashes are presented. Both women reported substantial improvements in the number of hot flashes experienced as well as in their quality of life as measured by the Menopause Quality of Life Scale (MENQOL), the ...

journal_title：Maturitas

authors： Allen LA,Dobkin RD,Boohar EM,Woolfolk RL

更新日期：2006-04-20 00:00:00

abstract：:Earlier menopause onset has been linked to a greater risk of cardiovascular disease. Both menopause onset and cardiovascular disease risk vary by geographical region, race/ethnicity and socioeconomic status. As such, it is plausible to hypothesize that these factors may influence the association of menopause onset and...

journal_title：Maturitas

authors： El Khoudary SR

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:The role of endogenous testosterone in the pathogenesis of type 2 diabetes mellitus remains vague. We investigated whether associations between endogenous testosterone and diabetes prevalence in men could be partially explained by modifiable risk factors. STUDY DESIGN:A random population-based cross-sectiona...

journal_title：Maturitas

authors： Atlantis E,Lange K,Martin S,Haren MT,Taylor A,O'Loughlin PD,Marshall V,Wittert GA

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:To investigate if women with a history of having experienced intimate partner violence (IPV) who undertook caregiving would experience worse mental and physical health compared to those without caregiving roles. STUDY DESIGN AND MAIN OUTCOME MEASURES:IPV, caregiving history and data on covariates were colle...

journal_title：Maturitas

authors： Ferreira P,Loxton D,Tooth LR

更新日期：2017-08-01 00:00:00