EMAS position statement: Bone densitometry screening for osteoporosis.

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of death in women after menopause. In essence major risk factors for CVD are similar in women as for men inclusive of serum lipid perturbations. The effects of estrogens and hormone replacement therapy on lipid metabolism is widely discussed and warrant furth...

journal_title：Maturitas

authors： Nerbrand C,Nyberg P,Nordström L,Samsioe G

更新日期：2002-05-20 00:00:00

abstract：OBJECTIVES:Modern data on endometrial cancer (EC) incidence demonstrate that it is one of the most prevalent gynecologic malignancies. It is possible that some allelic polymorphisms of the genes involved in steroidogenesis or steroid metabolism differently contribute into susceptibility to described types of this disea...

journal_title：Maturitas

authors： Berstein L,Zimarina T,Imyanitov E,Kovalevskij A,Maximov S,Pujol P,Thijssen J

更新日期：2006-07-20 00:00:00

abstract：:A group of 72 postmenopausal women were treated for 4 weeks with vaginal suppositories containing 0.5 or 1.0 mg of estriol. The two different doses achieved an identical significant improvement of urogenital symptoms, while a dose-related effect seen to be on climacteric complaints, according to a good absorption of e...

journal_title：Maturitas

authors： Bottiglione F,Volpe A,Esposito G,Aloysio DD

更新日期：1995-11-01 00:00:00

abstract：:The objective of this systematic review and meta-analysis was to evaluate the efficacy and the effectiveness, as well as the safety and tolerability, of urethral bulking agents (UBAs) in women with mixed or stress urinary incontinence. PubMed, Scopus, and the Cochrane Central Register of Controlled Trials were used to...

journal_title：Maturitas

authors： Capobianco G,Saderi L,Dessole F,Petrillo M,Dessole M,Piana A,Cherchi PL,Dessole S,Sotgiu G

更新日期：2020-03-01 00:00:00

abstract：:Estrogen is a well-known mitogen in human breast epithelium but the action of progestogen is complex and incompletely understood. During the last years, accumulating data from animal, clinical and observational studies suggest a proliferative effect in breast tissue when progestogen is added to estrogen. Findings in s...

journal_title：Maturitas

authors： Söderqvist G,von Schoultz B

更新日期：2004-09-24 00:00:00

abstract：OBJECTIVES:C-telopeptide crosslaps (CTX) and bone-specific alkaline phosphatase (BAP) do not provide sufficient sensitivity and specificity for diagnosis of osteoporosis. Cathepsin K (CatK), osteoprotegerin (OPG), and receptor activator of nuclear factor κB ligand (total (t) and soluble (s) RANKL) play an important rol...

journal_title：Maturitas

authors： Piatek S,Adolf D,Wex T,Halangk W,Klose S,Westphal S,Amthauer H,Winckler S

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:The present experiment examined the role of age and fall history in upper body accelerations when walking on an even and on an uneven surface. STUDY DESIGN:An observational cross-sectional study. MAIN OUTCOME MEASURES:The magnitude (root mean square [RMS]), symmetry (harmonic ratio) and attenuation (attenu...

journal_title：Maturitas

authors： Soleimanifar M,Mazaheri M,van Schooten KS,Asgari M,Mosallanezhad Z,Salavati M,Sedaghat-Nejad E,Parnianpour M

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Alterations in sleep quality and metabolism during menopause are improved by menopausal hormone therapy (MHT). The mechanisms mediating these effects remain unclear. Orexin A (OxA) is a neuro-peptide that regulates sleep/wakefulness, food intake and metabolism. This study examined changes in plasma OxA levels...

journal_title：Maturitas

authors： Cintron D,Beckman JP,Bailey KR,Lahr BD,Jayachandran M,Miller VM

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Previously, the REDLINC VI study showed that the main reason for the low use of menopausal hormone therapy (MHT) was its low rate of prescription by doctors. OBJECTIVE:To determine the use of MHT and perceived related risks among gynecologists. METHODS:A self-administered and anonymous questionnaire was de...

journal_title：Maturitas

authors： Danckers L,Blümel JE,Witis S,Vallejo MS,Tserotas K,Sánchez H,Salinas C,Saavedra J,Rojas JA,Onatra W,Ojeda E,Mostajo D,Morera F,Monterrosa A,Montaño A,Meruvia N,Martino M,Martínez J,Lima S,González E,Gómez G,Espi

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:Traditionally, general practitioners (GPs) are not involved in cancer-related treatment decisions, despite their often long relationship with patients, and their unique position to explore patients' values, especially with older patients. Therefore, we designed a randomised controlled trial to study the effect,...

journal_title：Maturitas

authors： Stegmann ME,Schuling J,Hiltermann TJ,Reyners AK,Burger H,Berger MY,Berendsen AJ

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:It has become popular to assert that Asian women in general have low midlife rates of reporting a wide variety of symptoms and that these rates are much lower than those found among women in western countries. Comparable data from mainland China remains sparse, however. This study aimed to uncover the sympto...

journal_title：Maturitas

authors： Shea JL

更新日期：2006-08-20 00:00:00

abstract：:Ageing of human skin may result from both the passage of time (intrinsic ageing) and from cumulative exposure to external influences (extrinsic ageing) such as ultraviolet radiation (UVR) which promote wrinkle formation and loss of tissue elasticity. Whilst both ageing processes are associated with phenotypic changes ...

journal_title：Maturitas

authors： Naylor EC,Watson RE,Sherratt MJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To compare the influence on lipid metabolism of two discontinuous, sequentially combined hormone replacement therapy (HRT) regimens. STUDY DESIGN:In an open, randomized study in 60 women, a full lipid profile including Lp(a) and liver function tests were assessed in a fasting state at the end of treatment cy...

journal_title：Maturitas

authors： Schram JH,Boerrigter PJ,The TY

更新日期：1995-09-01 00:00:00

abstract：:Fifty postmenopausal women requiring hormone replacement therapy for the treatment of climacteric symptoms were recruited in six centers. All patients received a new combined norethisterone acetate (NETA)/oestradiol (E2)-TTS, (Estragest TTS, Ciba-Geigy Ltd), delivering 0.25 mg NETA and 50 micrograms E2 per day, contin...

journal_title：Maturitas

authors： Oosterbaan HP,van Buuren AH,Schram JH,van Kempen PJ,Ubachs JM,van Leusden HA,Beyer GP

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:Estrogen replacement therapy (ERT) has been reported to affect blood pressure. Since natriuretic peptides have natriuretic and vasodilatory activity and also inhibit the renin-angiotensin-aldosterone system and lower blood pressure, it was hypothesized that the changes in blood pressure effected by ERT might ...

journal_title：Maturitas

authors： Karjalainen AH,Ruskoaho H,Vuolteenaho O,Heikkinen JE,Bäckström AC,Savolainen MJ,Kesäniemi YA

更新日期：2004-03-15 00:00:00

abstract：:The occurrence of uterine bleeding usually associated with hormonal replacement therapy is not acceptable for many women. Our objective was to review data on compliance and bleeding patterns in 70 postmenopausal women on oral replacement with estradiol 2 mg, estriol 1 mg, and norethisterone acetate 1 mg daily administ...

journal_title：Maturitas

authors： Dören M,Schneider HP

更新日期：1996-10-01 00:00:00

abstract：:To prevent hyperplasia and carcinoma of the endometrium during oestrogen replacement therapy (ORT), the addition of progestogens once a month is considered mandatory. However, there is no sound scientific basis for this assumption. As the addition of progestogens has several disadvantages, it is important to minimize ...

journal_title：Maturitas

authors： Meuwissen JH,van Langen H,Moret E,Navarro-Morquecho I

更新日期：1992-08-01 00:00:00

abstract：:Tibolone appears to be at least as efficacious as other forms of hormonal replacement therapy (HRT) on climacteric symptoms. It does not cause withdrawal bleeding when used in women with at least 1 year of amenorrhea. It is, therefore, not indicated in perimenopause because it may cause irregular bleeding. The androge...

journal_title：Maturitas

authors： Albertazzi P,Di Micco R,Zanardi E

更新日期：1998-11-16 00:00:00

abstract：:The aim of this chronobiological study was to investigate temporal correlations in the circadian patterns of 6 hormones, namely somatotrophic hormone (STH), prolactin (PRL), cortisol (F), aldosterone (ALD), insulin (IRI) and C-peptide (CP), assayed in systemic blood serum drawn at 07:00, 10:00, 13:00, 16:00, 19:00 and...

journal_title：Maturitas

authors： Cugini P,Lucia P,Tomassini R,Letizia C,Murano G,Scavo D,Tamburrano G,Maldonato A,Halberg F,Schramm A

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:To establish dose proportionality among four doses of a new estradiol transdermal system (ETS), Estradot, in healthy postmenopausal women and to evaluate the wear and irritation properties of the ETS. METHODS:In an open label, single-dose, randomized, four-period crossover study, healthy postmenopausal wome...

journal_title：Maturitas

authors： Hossain M,Quebe-Fehling E,Sergejew T,Schmidt G,Skerjanec A,Ibarra de Palacios P,Krinsky L

更新日期：2003-11-20 00:00:00

abstract：OBJECTIVES:Estrogen is often prescribed for symptoms and sequelae of ovarian estrogen loss after menopause. METHODS:To assess efficacy and acceptability of a new, highly soluble estrogen-calcium preparation, we formulated a water-soluble powdered combination of estrogen (0.625 mg estrone piperazine sulfate) and calciu...

journal_title：Maturitas

authors： Downey D,Spencer SJ,Deghenghi R,Jaffe RB

更新日期：2001-04-20 00:00:00

abstract：OBJECTIVE:In this study we aimed to pilot test the hypothesis that in women who are severely bothered by their menopausal complaints, improvement of menopausal symptoms is associated with an improvement in self-perceived work ability. STUDY DESIGN:This retrospective cohort study assessed the work ability of first-time...

journal_title：Maturitas

authors： Geukes M,Anema JR,van Aalst MP,de Menezes RX,Oosterhof H

更新日期：2019-02-01 00:00:00

abstract：:The increasing lifespan of the world population and the novel therapeutic combinations for the treatment of multiple myeloma (MM), which are more efficacious and safer, make the question of how to manage the older patient with MM increasingly relevant. Clinical trial data come mostly from subgroup analysis, as no clin...

journal_title：Maturitas

authors： Fotiou D,Ntanasis-Stathopoulos I,Gavriatopoulou M,Dimopoulos MA

更新日期：2020-08-01 00:00:00

abstract：:Multiple sclerosis (MS) is an autoimmune demyelinating and neurodegenerative condition of the central nervous system that preferentially afflicts women more than men. Low estrogen states such as menopause and the postpartum period favor exacerbations of multiple sclerosis in women with the disease. Existing and emergi...

journal_title：Maturitas

authors： Christianson MS,Mensah VA,Shen W

更新日期：2015-02-01 00:00:00

abstract：:The aim of this review was to systematically assess the effectiveness of aromatherapy for stress management. Seven databases were searched from their inception through April 2014. RCTs testing aromatherapy against any type of controls in healthy human person that assessed stress level and cortisol level were considere...

journal_title：Maturitas

authors： Hur MH,Song JA,Lee J,Lee MS

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:There is a global trend of increasing numbers of older women in the workforce. However, limited information is available regarding the relationship between the menopause transition and work, especially in developing countries. The objectives of this study were to investigate the relationship between experien...

journal_title：Maturitas

authors： Hammam RA,Abbas RA,Hunter MS

更新日期：2012-03-01 00:00:00

abstract：:Using the constant infusion technique we have measured the metabolic clearance rates (MCR) for delta 4-androstenedione (A), testosterone (T), oestrone (E1) and oestradiol (E2) in a large group of post-menopausal women. Their mean +/- SE age was 64.5 +/- 1.6 yr, their ages ranged from 46-90 yr. When the MCRs for each s...

journal_title：Maturitas

authors： Longcope C,Jaffee W,Griffing G

更新日期：1980-12-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the expression of oestrogen regulated genes in premenopausal and postmenopausal normal and malignant endometrial specimens. The molecular mechanisms and the role of these genes in endometrial carcinogenesis are poorly understood. METHODS:Normal and malignant endometrial ...

journal_title：Maturitas

authors： O'Toole SA,Dunn E,Sheppard BL,Sheils O,O'Leary JJ,Wuttke W,Seidlova-Wuttke D

更新日期：2005-06-16 00:00:00

abstract：OBJECTIVE:We investigated the association of visceral fat with the metabolic syndrome (MetS) and its separate components; the associations of both physical activity and muscle strength with the MetS and its separate components independent of visceral fat. Furthermore, we studied these associations within participants w...

journal_title：Maturitas

authors： Bisschop CN,Peeters PH,Monninkhof EM,van der Schouw YT,May AM

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Given the asymptomatic nature of osteoporosis, a fragility fracture provides an opportunity to make the issue of osteoporosis relevant to patients. Patients who link their fragility fracture with osteoporosis are more likely to initiate osteoporosis treatment, yet to date, we know little about who is likely t...

journal_title：Maturitas

authors： Sujic R,Gignac MA,Cockerill R,Beaton DE

更新日期：2013-10-01 00:00:00