Electrophysiological correlates of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism.

abstract：:Quantifying how close two datasets are to each other is a common and necessary undertaking in scientific research. The Pearson product-moment correlation coefficient r is a widely used measure of the degree of linear dependence between two data series, but it gives no indication of how similar the values of these seri...

journal_title：Scientific reports

authors： Duveiller G,Fasbender D,Meroni M

更新日期：2016-01-14 00:00:00

abstract：:Mammalian Eag1 (Kv10.1) potassium (K+) channels are widely expressed in the brain. Several mutations in the gene encoding human Eag1 K+ channel have been associated with congenital neurodevelopmental anomalies. Currently very little is known about the molecules mediating protein synthesis and degradation of Eag1 chann...

journal_title：Scientific reports

authors： Hsu PH,Ma YT,Fang YC,Huang JJ,Gan YL,Chang PT,Jow GM,Tang CY,Jeng CJ

更新日期：2017-01-18 00:00:00

abstract：:Most risk analysis models systematically underestimate the probability and impact of catastrophic events (e.g., economic crises, natural disasters, and terrorism) by not taking into account interconnectivity and interdependence of risks. To address this weakness, we propose the Cascading Alternating Renewal Process (C...

journal_title：Scientific reports

authors： Lin X,Moussawi A,Korniss G,Bakdash JZ,Szymanski BK

更新日期：2017-07-27 00:00:00

abstract：:Continuous, as opposed to pulsatile, delivery of hypothalamic gonadotropin-releasing hormone (GnRH) leads to a marked decrease in secretion of pituitary gonadotropins LH and FSH and impairment of reproductive function. Here we studied the expression profile of gonadotropin subunit and GnRH receptor genes in rat pituit...

journal_title：Scientific reports

authors： Janjic MM,Prévide RM,Fletcher PA,Sherman A,Smiljanic K,Abebe D,Bjelobaba I,Stojilkovic SS

更新日期：2019-12-27 00:00:00

abstract：:Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V). Several lines of evidence suggest that tanycytes may be involved in the regulation of energy homeostasis...

journal_title：Scientific reports

authors： Uranga RM,Millán C,Barahona MJ,Recabal A,Salgado M,Martinez F,Ordenes P,Elizondo-Vega R,Sepúlveda F,Uribe E,García-Robles MLÁ

更新日期：2017-06-16 00:00:00

abstract：:Mulching with organic materials is a management practice with long history for weed suppression, soil water conservation and erosion control. Its potential impact on crop pests is less well explored. Here we report its utility for reducing crop damage by the serious pest, sweetpotato weevil (Cylas formicarius). Labora...

journal_title：Scientific reports

authors： Rehman M,Liu J,Johnson AC,Dada TE,Gurr GM

更新日期：2019-10-16 00:00:00

abstract：:Human female germline stem cells (FGSCs) have opened new opportunities for understanding human oogenesis, delaying menopause, treating infertility, and providing a new strategy for preserving fertility. However, the shortage of adult human ovaries tissues available impedes their future investigations and clinical appl...

journal_title：Scientific reports

authors： Ding X,Liu G,Xu B,Wu C,Hui N,Ni X,Wang J,Du M,Teng X,Wu J

更新日期：2016-06-30 00:00:00

abstract：:Living organisms in drying environments build anisotropic structures and exhibit directionality through self-organization of biopolymers. However, the process of macro-scale assembly is still unknown. Here, we introduce a dissipative structure through a non-equilibrium process between hydration and deposition in the d...

journal_title：Scientific reports

authors： Okeyoshi K,Okajima MK,Kaneko T

更新日期：2017-07-21 00:00:00

abstract：:Dietary exposure of insects to a feeding deterrent substance for hours to days can induce habituation and concomitant desensitization of the response of peripheral gustatory neurons to such a substance. In the present study, larvae of the herbivore Helicoverpa armigera were fed on diets containing either a high, mediu...

journal_title：Scientific reports

authors： Ma Y,Li J,Tang Q,Zhang X,Zhao X,Yan F,van Loon JJ

更新日期：2016-12-14 00:00:00

abstract：:Thaumatin is an intensely sweet-tasting protein that elicits sweet taste at a concentration of 50 nM, a value 100,000 times larger than that of sucrose on a molar basis. Here we attempted to produce a protein with enhanced sweetness by removing negative charges on the interacting side of thaumatin with the taste recep...

journal_title：Scientific reports

authors： Masuda T,Ohta K,Ojiro N,Murata K,Mikami B,Tani F,Temussi PA,Kitabatake N

更新日期：2016-02-03 00:00:00

abstract：:Due to the potentially detrimental consequences of low performance in basic functional tasks, individuals are expected to improve performance with age and show the most marked changes during early stages of life. Soaring-gliding birds use rising-air columns (thermals) to reduce energy expenditure allocated to flight. ...

journal_title：Scientific reports

authors： Harel R,Horvitz N,Nathan R

更新日期：2016-06-13 00:00:00

abstract：:Sacroiliac (SI) screw loosening may indicate persistent instability, non-union and contribute to pain. Yet, there is no reliable objective measurement technique to detect and monitor SI screw loosening. In 9 cadaveric pelvises one of two SI screw was turned back approximately 20 mm and subsequently assessed by optical...

journal_title：Scientific reports

authors： Pieroh P,Lenk M,Hohmann T,Grunert R,Wagner D,Josten C,Höch A,Böhme J

更新日期：2019-02-28 00:00:00

abstract：:Proteasomes are a critical component of quality control that regulate turnover of short-lived, unfolded, and misfolded proteins. Proteasome activity has been therapeutically targeted and considered as a treatment option for several chronic lung disorders including pulmonary fibrosis. Although pharmacologic inhibition ...

journal_title：Scientific reports

authors： Sitaraman S,Na CL,Yang L,Filuta A,Bridges JP,Weaver TE

更新日期：2019-08-29 00:00:00

abstract：:Tropical Pacific variability (TPV) heavily influences global climate, but much is still unknown about its drivers. We examine the impact of South Pacific variability on the modes of TPV: the El Niño-Southern Oscillation (ENSO) and the Interdecadal Pacific Oscillation (IPO). We conduct idealised coupled experiments in ...

journal_title：Scientific reports

authors： Chung CTY,Power SB,Sullivan A,Delage F

更新日期：2019-12-04 00:00:00

abstract：:Alterations in muscle milieu are suggested as important activity of peripheral drive in patients with chronic musculoskeletal pain (CMP). Microdialysis (MD) has been used in monitoring altered metabolic response pattern in muscles. However, the insertion of MD probe causes a local tissue trauma. Whether and how metabo...

journal_title：Scientific reports

authors： Sørensen LB,Gazerani P,Wåhlén K,Ghafouri N,Gerdle B,Ghafouri B

更新日期：2018-02-14 00:00:00

abstract：:17α-ethynilestradiol (EE2) and tamoxifen (Tmx) are pollutants world-wide distributed in aquatic environments. Gilthead seabream, Sparus aurata L., is highlighted as a species model of intensively culture in anthropogenic disturbed environments. The effects of these pollutants on gilthead seabream reproduction and some...

journal_title：Scientific reports

authors： Valero Y,López-Cánovas AE,Rodenas MC,Cabas I,García-Hernández P,Arizcun M,García-Ayala A,Chaves-Pozo E

更新日期：2020-05-14 00:00:00

abstract：:Centromeres usually contain large amounts of tandem repeat DNA. Alpha satellite DNA (AS) is the most abundant tandem repeat DNA found in the centromeres of simian primates. The AS of humans contains sequences organized into higher-order repeat (HOR) structures, which are tandem arrays of larger repeat units consisting...

journal_title：Scientific reports

authors： Sujiwattanarat P,Thapana W,Srikulnath K,Hirai Y,Hirai H,Koga A

更新日期：2015-05-14 00:00:00

abstract：:The functionalization of graphene remains an important challenge for numerous applications expected by this fascinating material. To keep advantageous properties of graphene after modification or functionalization of its structure, local approaches are a promising road. A novel technique is reported here that allows p...

journal_title：Scientific reports

authors： Li H,Daukiya L,Haldar S,Lindblad A,Sanyal B,Eriksson O,Aubel D,Hajjar-Garreau S,Simon L,Leifer K

更新日期：2016-01-29 00:00:00

abstract：:Delta-9-tetrahydrocannabinol (THC) is the primary psychoactive compound in Cannabis, which is studied extensively for its medicinal value. A central gap in the science is the underlying mechanisms surrounding THC's therapeutic effects and the role of gut metabolite profiles. Using a mass-spectrometry based metabolomic...

journal_title：Scientific reports

authors： Oza M,Becker W,Gummadidala PM,Dias T,Omebeyinje MH,Chen L,Mitra C,Jesmin R,Chakraborty P,Sajish M,Hofseth LJ,Banerjee K,Wang Q,Moeller PDR,Nagarkatti M,Nagarkatti P,Chanda A

更新日期：2019-07-19 00:00:00

abstract：:Increasing grain zinc (Zn) concentration of cereals for minimizing Zn malnutrition in two billion people represents an important global humanitarian challenge. Grain Zn in field-grown wheat at the global scale ranges from 20.4 to 30.5 mg kg-1, showing a solid gap to the biofortification target for human health (40 mg ...

journal_title：Scientific reports

authors： Chen XP,Zhang YQ,Tong YP,Xue YF,Liu DY,Zhang W,Deng Y,Meng QF,Yue SC,Yan P,Cui ZL,Shi XJ,Guo SW,Sun YX,Ye YL,Wang ZH,Jia LL,Ma WQ,He MR,Zhang XY,Kou CL,Li YT,Tan DS,Cakmak I,Zhang FS,Zou CQ

更新日期：2017-08-01 00:00:00

abstract：:Endothelium-dependent flow-mediated dilation (ED-FMD), a biophysical marker of endothelial dysfunction, is apparently impaired in patients with systemic lupus erythematosus (SLE) but such observation is inconsistent. Here, we assessed and compared the brachial artery ED-FMD (baED-FMD) using ultrasonography between SLE...

journal_title：Scientific reports

authors： Mak A,Kow NY,Schwarz H,Gong L,Tay SH,Ling LH

更新日期：2017-08-04 00:00:00

abstract：:Ethidium bromide (EB) and acridine orange (AO) bind to nucleic acids and are thus considered as potential mutagens. In this study, the effects of EB and AO on the germination behaviours of white, yellow, red, and purple maize seeds were investigated. The results indicate that low concentrations of EB (50 μg mL-1) and ...

journal_title：Scientific reports

authors： Zhang Y,Shi H,Deng B

更新日期：2018-09-19 00:00:00

abstract：:Our study purpose was to evaluate mitochondrial (mt)DNA and RNA in peripheral blood mononuclear cells (PBMCs) and body shape changes (BSC) in HBV-infected patients. mtDNA and mtRNA were measured in PBMCs. The presence of BSC was evaluated through a questionnaire and clinical evaluation. A total of 157 subjects were en...

journal_title：Scientific reports

authors： Madeddu G,Fiore V,Melis M,Ortu S,Mannu F,Muredda AA,Garrucciu G,Bandiera F,Zaru S,Bagella P,Calvisi DF,Babudieri S

更新日期：2020-02-06 00:00:00

abstract：:It is essential to understand how the loss of biodiversity impacts both ecosystem function (EF) and multifunctionality (EMF). Previous studies have mostly focused on predicting how species richness (SR) impacts EMF, while the effect of functional diversity (FD) on EMF remains unclear. Specifically, we know little abou...

journal_title：Scientific reports

authors： Huang X,Su J,Li S,Liu W,Lang X

更新日期：2019-05-06 00:00:00

abstract：:Maternal overnutrition increases the risk of long-term metabolic dysfunction in offspring. Exercise improves metabolism partly by upregulating mitochondrial biogenesis or function, via increased levels of nicotinamide adenine dinucleotide (NAD+). We have shown that the NAD+ precursor, nicotinamide mononucleotide (NMN)...

journal_title：Scientific reports

authors： Uddin GM,Youngson NA,Doyle BM,Sinclair DA,Morris MJ

更新日期：2017-11-08 00:00:00

abstract：:Postsynaptic density-95/Discs large/Zonula occludens-1 (PDZ) domain-mediated protein interactions play pivotal roles in various molecular biological events, including protein localisation, assembly, and signal transduction. Although the vertebrate regulator of planar cell polarity Van Gogh-like 2 (Vangl2) was recently...

journal_title：Scientific reports

authors： Nagaoka T,Tabuchi K,Kishi M

更新日期：2015-08-10 00:00:00

abstract：:Male specific DNA sequences were selected from a Diversity Arrays Technology (DArT) mapping study to evaluate their suitability for determination of the sex phenotype among young seedlings in a hop (Humulus lupulus L.) breeding program. Ten male specific DArT markers showed complete linkage with male sex phenotype in ...

journal_title：Scientific reports

authors： Čerenak A,Kolenc Z,Sehur P,Whittock SP,Koutoulis A,Beatson R,Buck E,Javornik B,Škof S,Jakše J

更新日期：2019-10-02 00:00:00

abstract：:Increased evidence suggests that dysregulation of cholesterol metabolism may be a key event contributing to progression of multiple sclerosis (MS). Using an experimental autoimmune encephalomyelitis (EAE) model of MS we revealed specific changes in the mRNA and protein expression of key molecules involved in the maint...

journal_title：Scientific reports

authors： Lavrnja I,Smiljanic K,Savic D,Mladenovic-Djordjevic A,Tesovic K,Kanazir S,Pekovic S

更新日期：2017-06-02 00:00:00

abstract：:Novel bioplastic films derived from wool keratins were prepared by protein solution in an alkaline mild oxidative method that splits disulphide (-S-S-) bonds. The native structure of the keratin macromolecules was partially modified upon extraction as revealed by the decrease of the β-sheet to α-helices/coils ratio bu...

journal_title：Scientific reports

authors： Fernández-d'Arlas B

更新日期：2019-10-15 00:00:00

abstract：:We show that ATM kinase inhibition using AZ31 prior to 9 or 9.25 Gy total body irradiation (TBI) reduced median time to moribund in mice to 8 days. ATR kinase inhibition using AZD6738 prior to TBI did not reduce median time to moribund. The striking finding associated with ATM inhibition prior to TBI was increased cry...

journal_title：Scientific reports

authors： Vendetti FP,Leibowitz BJ,Barnes J,Schamus S,Kiesel BF,Abberbock S,Conrads T,Clump DA,Cadogan E,O'Connor MJ,Yu J,Beumer JH,Bakkenist CJ

更新日期：2017-02-01 00:00:00