Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation.

abstract：:Global biodiversity hotspots (GBHs) are increasingly vulnerable to human stressors such as anthropogenic climate change, which will alter the ecology of these habitats, even where protected. The longleaf pine (Pinus palustris) ecosystem (LPE) of the North American Coastal Plain is a GBH where disturbances are integral...

journal_title：Scientific reports

authors： Zampieri NE,Pau S,Okamoto DK

更新日期：2020-05-21 00:00:00

abstract：:Little is known about circulating biomarkers of vascular injury in relation to cardiovascular disease risk. Thus, we evaluated associations between six novel markers (E-Selectin, P-Selectin, thrombomodulin, thrombopoietin, intercellular adhesion molecule 3 and GPIIb/IIIa) and established cardiovascular risk factors as...

journal_title：Scientific reports

authors： Pletsch-Borba L,Grafetstätter M,Hüsing A,González Maldonado S,Kloss M,Groß ML,Johnson T,Sookthai D,Bugert P,Kaaks R,Kühn T

更新日期：2019-02-28 00:00:00

abstract：:Nano-flowers reported so far were mostly constituted of inorganic or hybrid materials. We have synthesized and crystallized a new organic compound, 1, 2-bis(tritylthio)ethane forming an organic nano-flower consisting of single crystalline petals. Crystal structure at nano and micro level indicates that π-π stacking in...

journal_title：Scientific reports

authors： Sasidharan S,P C S,Chaudhary N,Ramakrishnan V

更新日期：2017-12-11 00:00:00

abstract：:Gold is a noble metal typically stable as a solid in a face-centered cubic (FCC) structure under ambient conditions; however, under particular circumstances aberrant allotropes have been synthesized. In this work, we document the phase transformation of 25 nm thick nanocrystalline (NC) free-standing gold thin-film via...

journal_title：Scientific reports

authors： Suri PK,Nathaniel JE 2nd,Li N,Baldwin JK,Wang Y,Hattar K,Taheri ML

更新日期：2020-10-20 00:00:00

abstract：:Hepatic encephalopathy is a neuropsychiatric syndrome evolving from cerebral osmotic disturbances and oxidative/nitrosative stress. Ammonia, the main toxin of hepatic encephalopathy, triggers astrocyte senescence in an oxidative stress-dependent way. As miRNAs are critically involved in cell cycle regulation and their...

journal_title：Scientific reports

authors： Oenarto J,Karababa A,Castoldi M,Bidmon HJ,Görg B,Häussinger D

更新日期：2016-01-12 00:00:00

abstract：:Ultrafast betatron x-ray emission from electron oscillations in laser wakefield acceleration (LWFA) has been widely investigated as a promising source. Betatron x-rays are usually produced via self-injected electron beams, which are not controllable and are not optimized for x-ray yields. Here, we present a new method...

journal_title：Scientific reports

authors： Huang K,Li YF,Li DZ,Chen LM,Tao MZ,Ma Y,Zhao JR,Li MH,Chen M,Mirzaie M,Hafz N,Sokollik T,Sheng ZM,Zhang J

更新日期：2016-06-08 00:00:00

abstract：:How the human auditory system learns to map complex pinna-induced spectral-shape cues onto veridical estimates of sound-source elevation in the median plane is still unclear. Earlier studies demonstrated considerable sound-localisation plasticity after applying pinna moulds, and to altered vision. Several factors may ...

journal_title：Scientific reports

authors： Zonooz B,Arani E,Opstal AJV

更新日期：2018-12-18 00:00:00

abstract：:Hand size perceptual distortions characterize adult human cognition. Notwithstanding the importance of uncovering how hand size representation develops in humans, studies in this field are still at a preliminary stage. Indeed, it is yet to be understood whether hand size distortions are present and reliable in early c...

journal_title：Scientific reports

authors： Giurgola S,Bolognini N,Nava E

更新日期：2020-03-25 00:00:00

abstract：:In the European Union, the use of recombinant bovine somatotropin (rbST) in dairy cattle is forbidden. Monitoring rbST (ab)use by its direct detection in animal matrices still remains a challenging task. New monitoring methods based on indirect detection of the substance are necessary. A new transcriptomic system base...

journal_title：Scientific reports

authors： Lamas A,Regal P,Vázquez B,Miranda JM,Cepeda A,Franco CM

更新日期：2019-03-18 00:00:00

abstract：:Krüppel-like factor 6 (KLF6) is a transcription factor and tumor suppressor. We previously identified KLF6 as mediator of hepatocyte glucose and lipid homeostasis. The loss or reduction of KLF6 is linked to the progression of hepatocellular carcinoma, but its contribution to liver regeneration and repair in acute live...

journal_title：Scientific reports

authors： Sydor S,Manka P,Best J,Jafoui S,Sowa JP,Zoubek ME,Hernandez-Gea V,Cubero FJ,Kälsch J,Vetter D,Fiel MI,Hoshida Y,Bian CB,Nelson LJ,Moshage H,Faber KN,Paul A,Baba HA,Gerken G,Friedman SL,Canbay A,Bechmann LP

更新日期：2017-08-14 00:00:00

abstract：:Bats have been shown as important mammal resevoirs to carry a variety of zoonotic pathogens. To analyze pathogenic species in bats from southeast coastal regions of China, we performed metagenomic sequencing technology for high throughput sequencing of six sentinels from southeast coastal area of China. We obtained 5,...

journal_title：Scientific reports

authors： Hu D,Zhu C,Wang Y,Ai L,Yang L,Ye F,Ding C,Chen J,He B,Zhu J,Qian H,Xu W,Feng Y,Tan W,Wang C

更新日期：2017-09-07 00:00:00

abstract：:Strongly interacting one-dimensional quantum systems often behave in a manner that is distinctly different from their higher-dimensional counterparts. When a particle attempts to move in a one-dimensional environment it will unavoidably have to interact and 'push' other particles in order to execute a pattern of motio...

journal_title：Scientific reports

authors： Dehkharghani A,Volosniev A,Lindgren J,Rotureau J,Forssén C,Fedorov D,Jensen A,Zinner N

更新日期：2015-06-15 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xue Q,Li X,Gu Y,Wang X,Wang M,Tian J,Duan X,Gao H,Ji X,Yan X,Dong W,Fang Q,Zhang X

更新日期：2020-05-08 00:00:00

abstract：:HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV (PLWH). The use of cocaine by PLWH exacerbates neuronal dysfunction. Here, we examined the mechanisms by ...

journal_title：Scientific reports

authors： Mohseni Ahooyi T,Shekarabi M,Torkzaban B,Langford TD,Burdo TH,Gordon J,Datta PK,Amini S,Khalili K

更新日期：2018-11-02 00:00:00

abstract：:Stable electroluminescence from micro-pixelated light-emitting diode (μLED) occurs when electrons and holes are continuously injected from external electrodes. Different from the general recognition, in this work, μLED works in an operation mode, namely, non-electrical contact and non-carrier injection mode, and can b...

journal_title：Scientific reports

authors： Wang K,Liu Y,Wu C,Li D,Lv S,Zhang Y,Zhou X,Guo T

更新日期：2020-05-15 00:00:00

abstract：:As a two-dimensional material, graphene has attracted increasing attention as heat dissipation material owing to its excellent thermal transport property. In this work, we fabricated sisal nanocrystalline cellulose/functionalized graphene papers (NPGs) with high thermal conductivity by vacuum-assisted self-assembly me...

journal_title：Scientific reports

authors： Ren L,Wang M,Lu S,Pan L,Xiong Z,Zhang Z,Peng Q,Li Y,Yu J

更新日期：2019-03-14 00:00:00

abstract：:Selective removal of lignin and other recalcitrant compounds, collectively registered as acid-unhyrolyzable residue (AUR), results in bleaching of leaf litter, but the importance of bleaching in decomposition processes on forest soil has not been fully evaluated. The aims of this study were to elucidate the occurrence...

journal_title：Scientific reports

authors： Osono T,Hiradate S,Hobara S

更新日期：2021-01-19 00:00:00

abstract：:Maintaining energy balance over a wide range of temperatures is critical for an active pelagic fish species such as the mahi-mahi (Coryphaena hippurus), which can experience rapid changes in temperature during vertical migrations. Due to the profound effect of temperature on mitochondrial function, this study was desi...

journal_title：Scientific reports

authors： Lau GY,Cox GK,Stieglitz JD,Benetti DD,Grosell M

更新日期：2020-09-10 00:00:00

abstract：:Plant litter represents a major basal resource in streams, where its decomposition is partly regulated by litter traits. Litter-trait variation may determine the latitudinal gradient in decomposition in streams, which is mainly microbial in the tropics and detritivore-mediated at high latitudes. However, this hypothes...

journal_title：Scientific reports

authors： Boyero L,Graça MAS,Tonin AM,Pérez J,J Swafford A,Ferreira V,Landeira-Dabarca A,A Alexandrou M,Gessner MO,McKie BG,Albariño RJ,Barmuta LA,Callisto M,Chará J,Chauvet E,Colón-Gaud C,Dudgeon D,Encalada AC,Figueroa R,Fle

更新日期：2017-09-05 00:00:00

abstract：:The CRISPR-Cas9 system has a potential for wide application in organisms that particularly present low homologous integration rates. In this study, we developed three different methods using this system to replace a gene through homology-directed repair in the plant pathogenic fungus Colletotrichum sansevieriae, which...

journal_title：Scientific reports

authors： Nakamura M,Okamura Y,Iwai H

更新日期：2019-12-12 00:00:00

abstract：:Adaptation to systematic visual distortions is well-documented but there is little evidence of similar adaptation to radical changes in audition. We use a pseudophone to transpose the sound streams arriving at the left and right ears, evaluating the perceptual effects it provokes and the possibility of learning to loc...

journal_title：Scientific reports

authors： Bermejo F,Di Paolo EA,Gilberto LG,Lunati V,Barrios MV

更新日期：2020-03-12 00:00:00

abstract：:Leaching of nitrate from fertilisers diminishes nitrogen use efficiency (the portion of nitrogen used by a plant) and is a major source of agricultural pollution. To improve nitrogen capture, grasses such as brachiaria are increasingly used, especially in South America and Africa, as a cover crop, either via intercrop...

journal_title：Scientific reports

authors： Galdos MV,Brown E,Rosolem CA,Pires LF,Hallett PD,Mooney SJ

更新日期：2020-03-19 00:00:00

abstract：:Unpleasant emotional distraction can impair the retention of non-emotional information in working memory (WM). Research links the prefrontal cortex with the successful control of such biologically relevant distractors, although the temporal changes in this brain mechanism remain unexplored. We use magnetoencephalograp...

journal_title：Scientific reports

authors： García-Pacios J,Garcés P,Del Río D,Maestú F

更新日期：2015-06-12 00:00:00

abstract：:Local polarization of a magnetic layer, a well-known method for storing information, has found its place in numerous applications such as the popular magnetic drawing board toy or the widespread credit cards and computer hard drives. Here we experimentally show that a similar principle can be applied for imprinting th...

journal_title：Scientific reports

authors： Brisbois J,Motta M,Avila JI,Shaw G,Devillers T,Dempsey NM,Veerapandian SK,Colson P,Vanderheyden B,Vanderbemden P,Ortiz WA,Nguyen ND,Kramer RB,Silhanek AV

更新日期：2016-06-06 00:00:00

abstract：:Predicting regions at risk from introductions of non-native species and the subsequent invasions is a fundamental aspect of horizon scanning activities that enable the development of more effective preventative actions and planning of management measures. The Asian cyprinid fish topmouth gudgeon Pseudorasbora parva ha...

journal_title：Scientific reports

authors： Fletcher DH,Gillingham PK,Britton JR,Blanchet S,Gozlan RE

更新日期：2016-05-20 00:00:00

abstract：:Several anti-cancer therapies target the epidermal growth factor receptor (EGFR). Radionuclide imaging of EGFR expression in tumours may aid in selection of optimal cancer therapy. The 111In-labelled DOTA-conjugated ZEGFR:2377 Affibody molecule was successfully used for imaging of EGFR-expressing xenografts in mice. A...

journal_title：Scientific reports

authors： Garousi J,Andersson KG,Dam JH,Olsen BB,Mitran B,Orlova A,Buijs J,Ståhl S,Löfblom J,Thisgaard H,Tolmachev V

更新日期：2017-07-20 00:00:00

abstract：:Insufficient glenoid fixation is one of the main reasons for failure in total shoulder arthroplasty. This is predominantly caused by the inert nature of the ultra-high molecular weight polyethylene (UHMWPE) used in the glenoid component of the implant, which makes it difficult to adhesively bind to bone cement or bone...

journal_title：Scientific reports

authors： Van Vrekhem S,Vloebergh K,Asadian M,Vercruysse C,Declercq H,Van Tongel A,De Wilde L,De Geyter N,Morent R

更新日期：2018-03-16 00:00:00

abstract：:Cardiovascular diseases are directly linked to smoking habits, which has both physiological and anatomical effects on the systemic and retinal circulations, and these changes can be detected with fundus photographs. Here, we aimed to 1- design a Convolutional Neural Network (CNN), using retinal photographs, to differe...

journal_title：Scientific reports

authors： Vaghefi E,Yang S,Hill S,Humphrey G,Walker N,Squirrell D

更新日期：2019-05-09 00:00:00

abstract：:Betaine alleviates high-fat diet-induced fatty liver and prenatal betaine programs offspring hepatic lipid metabolism. Excessive corticosterone (CORT) exposure causes fatty liver in chickens, yet it remains unknown whether and how prenatal betaine modulates the susceptibility of CORT-induced fatty liver later in life....

journal_title：Scientific reports

authors： Hu Y,Sun Q,Liu J,Jia Y,Cai D,Idriss AA,Omer NA,Zhao R

更新日期：2017-01-06 00:00:00

abstract：:The adipokines chemerin and omentin-1 have been suggested to influence cardiovascular function. The study aimed to investigate the longitudinal association between chemerin, omentin-1 concentrations and risk of incident heart failure (HF), respectively. We conducted a case-cohort study nested within the European Prosp...

journal_title：Scientific reports

authors： Menzel J,di Giuseppe R,Biemann R,Wittenbecher C,Aleksandrova K,Eichelmann F,Fritsche A,Schulze MB,Boeing H,Isermann B,Weikert C

更新日期：2017-10-26 00:00:00