Abstract：
:In one of the most-widely used species in pineal gland research, the strongly photoperiodic golden hamster, Mesocricetus auratus, no electrophysiological data on pinealocytes are currently available. To fill this gap, in the present study 185 spontaneously active pinealocytes from male golden hamsters were recorded extracellularly, both during day- and night-time (light: dark cycle 12: 12, lights on at 07.00 h). As in other species, pinealocytes exhibited action potentials of 1-2 ms duration. An irregular firing pattern was observed in 95% of the pinealocytes, the remainder fired more regularly or showed a phasic discharge pattern. The firing frequencies ranged from 0.2 to 25 Hz and showed clear time-dependent differences. From 07.00 h to 22.00 h the mean firing frequencies were identical, i.e. in the range of 2 Hz; between 22.00 h and 01.00 h mean discharge rate increased to 5 Hz and exhibited a peak of 7 Hz between 01.00 h and 04.00 h, followed by a decrease to 4 Hz between 04.00 h and 07.00 h. Electrical stimulation of the superior cervical ganglion during day-time resulted in an augmentation of firing frequency in some pinealocytes and a decrease in others; during night-time, inhibitory responses only were observed. Photic stimulation, or electrical stimulation of either the optic chiasm or the habenular nuclei mostly decreased the firing rate of pinealocytes. Compared to other mammalian species, the electrophysiological properties of golden hamster pinealocytes appear to be basically similar.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Stehle J,Reuss S,Vollrath Ldoi
10.1007/BF00269449subject
Has Abstractpub_date
1987-01-01 00:00:00pages
27-32issue
1eissn
0014-4819issn
1432-1106journal_volume
67pub_type
杂志文章abstract：:The ability of Huntington's disease patients to co-ordinate their two hands with and without external cueing was investigated. Twelve Huntington's disease patients and sex- and age-matched controls performed a bimanual cranking task at two speeds (0.5 Hz, 1.5 Hz) and phase relationships (in-phase, anti-phase), with an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000485
更新日期：2000-10-01 00:00:00
abstract：:Activation of glial cells has been proposed to contribute to neuronal dysfunction and neuronal cell death in Alzheimer's disease. In this study, we attempt to determine some of the effects of secreted factors from activated murine N-11 microglia on viability and morphology of neurons using the differentiated neuroblas...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1389-5
更新日期：2003-05-01 00:00:00
abstract：:A series of step-tracking experiments was conducted before, during, and after a 3-week space mission to assess the effects of prolonged microgravity on a non-postural motor-control task. In- and post-flight accuracy was affected only marginally. However, kinematic analyses revealed a considerable change in the underly...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050906
更新日期：1999-12-01 00:00:00
abstract：:In a previous study, we found that haptic guidance from a robotic steering wheel can improve short-term learning of steering of a simulated vehicle, in contrast to several studies of other tasks that had found that the guidance either impairs or does not aid motor learning. In this study, we examined whether haptic gu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2026-8
更新日期：2010-03-01 00:00:00
abstract：:Recent animal studies have found neuronal expression of major histocompatibility complex (MHC) class I in the central nervous system (CNS). However, the developmental expression profiles of MHC class I in human CNS remain unclear. Here, we systemically evaluate the expression and subcellular localization of MHC class ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4345-2
更新日期：2015-09-01 00:00:00
abstract：:Seizure susceptibility waxes and wanes in an apparently circadian manner in many epileptic patients. Fluctuations of melatonin concentration with highest levels during the night and lowest levels in the early morning could be involved in this phenomenon. Therefore, the action of melatonin on epileptic activity was tes...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230052
更新日期：1995-01-01 00:00:00
abstract：:Despite holding significant promise for counteracting the deleterious effects of ageing on cognitive and motor function, little is known of the effects of facilitatory non-invasive brain stimulation (NBS) techniques on corticospinal excitability (CSE) in older adults. Thirty-three older adults (≥60 years) participated...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4740-3
更新日期：2016-12-01 00:00:00
abstract：:This article investigated both the ability of naive human subjects to learn interval production, as well as the properties of learning generalization across modalities and interval durations that varied systematically from the over-trained interval. Human subjects trained on a 450-, 650-, or 850-ms single-interval pro...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1895-1
更新日期：2009-07-01 00:00:00
abstract：:Serotonin reveals ineffective (subthreshold) pathways from the C2 lateral funiculus to ipsilateral phrenic motoneurons in spinalized rats. The objective of the present study was to investigate serotonergic modulation of crossed-spinal pathways to contralateral phrenic motoneurons. Rats (n = 10) were anesthetized (uret...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00243214
更新日期：1994-01-01 00:00:00
abstract：:In order to see whether septal neurones are connected to the hypothalamic neurones secreting vasopressin or oxytocin, neurones in different regions of the septum were recorded during electrical stimulation of the supraoptic nucleus. The position of the stimulating electrode within the latter was verified using lactati...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237493
更新日期：1981-01-01 00:00:00
abstract：:Reactive responses to balance perturbations have been shown to be improved by training. This investigation aimed to compare the effects of block and random training perturbation schedules on stability gains of compensatory arm and leg movements in response to unpredictable large-magnitude balance perturbations. Pertur...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05806-x
更新日期：2020-05-01 00:00:00
abstract：:We sought to determine whether motor evoked potentials (MEPs) as well as silent periods could be produced in hand and shoulder muscles by transcranial magnetic stimulation (TMS) of the ipsilateral cerebral hemisphere and, if so, whether their cortical representations could be mapped with respect to those of contralate...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/BF00227284
更新日期：1994-01-01 00:00:00
abstract：:Previous studies have used a secondary probe reaction time (RT) task to assess attentional demands of a primary task. The current study used a startling acoustic stimulus (SAS) in a probe RT paradigm to test the hypothesis that attentional resources would be directly related to limitations in response preparation. Par...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4340-7
更新日期：2015-09-01 00:00:00
abstract：:Activities of 53 neurons in the brain stem were recorded with chronically implanted fine wires in freely eating and drinking rats. Twenty units were isolated from the trigeminal mesencephalic nucleus; 18 were spindle afferents and 2 periodontal afferents. The spindle units were classified into 4 types: 5 units showed ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247896
更新日期：1989-01-01 00:00:00
abstract：:We examined the lower limb joint kinematics observed during pre- and postflight treadmill walking performed by seven subjects from three Space Shuttle flights flown between March 1992 and February 1994. Basic temporal characteristics of the gait patterns, such as stride time and duty cycle, showed no significant chang...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227650
更新日期：1996-11-01 00:00:00
abstract：:Our perception of the vertical depends on allocentric information about the visual surrounds, egocentric information about the own body axis and gravicentric information about the pull of gravity. Previous work has documented that some individuals rely strongly on allocentric information, while others do not, and the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4526-z
更新日期：2016-04-01 00:00:00
abstract：:In the metadata of the original publication of the article. ...
journal_title：Experimental brain research
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00221-019-05476-4
更新日期：2019-02-01 00:00:00
abstract：:The aim of this work was to study the neurochemical effects in the brain of GABA-transaminase inhibition by systemic administration of gabaculine (100 mg/kg, i.a.) in the rat. In order to investigate neurotransmitter and related amino-acid compartmentation and metabolism, we have developed an original tool: the coupli...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050802
更新日期：1999-08-01 00:00:00
abstract：:Grasping using two forelimbs in opposition to one another is evolutionary older than the hand with an opposable thumb (Whishaw and Coles in Behav Brain Res 77:135-148, 1996); yet, the mechanisms for bimanual grasps remain unclear. Similar to unimanual grasping, the localization of matching stable grasp points on an ob...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3643-9
更新日期：2013-10-01 00:00:00
abstract：:In order to determine the responses of paraventricular nucleus neurones following activation of central serotonergic pathways, single unit activity was recorded and responses following electrical stimulation of the midbrain dorsal raphe nucleus were examined. Excitation was recorded from approximately 50% of the cells...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228913
更新日期：1989-01-01 00:00:00
abstract：:According to the peak and decline model divergent thinking declines at a specific age (in or after middle age). However, if divergent thinking declines steadily in aging still has to be clarified. In order to explore the age-related changes in verbal and visual divergent thinking, in the present study a sample of 159 ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4857-4
更新日期：2017-04-01 00:00:00
abstract：:Humans are extraordinarily skilled in the tactile evaluation of, and differentiation between, surfaces. The chemical and mechanical properties of these surfaces are translated into tactile signals during haptic exploration by mechanoreceptors in our skin, which are specialized to respond to different types of temporal...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05831-w
更新日期：2020-06-01 00:00:00
abstract：:Two components of long-term potentiation (LTP) are distinguished with extracellular recording electrodes: a synaptic and an EPSP-Spike (E-S) component. The latter consists of the enhancement produced in the population spike amplitude in excess of that predicted by EPSP potentiation alone. The experiments carried out i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229331
更新日期：1990-01-01 00:00:00
abstract：:We used the framework of the uncontrolled manifold (UCM) hypothesis to analyze the structure of finger force variability in discrete (ramp) and oscillatory force production tasks performed by the index and middle fingers of the right hand acting in parallel. Subjects performed the tasks at fast and slow rates, with an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1196-4
更新日期：2002-10-01 00:00:00
abstract：:Using combined psychophysics and event-related potentials (ERPs), we investigated the effect of perceptual learning on face gender discrimination and probe the neural correlates of the learning effect. Human subjects were trained to perform a gender discrimination task with male or female faces. Before and after train...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3396-x
更新日期：2013-04-01 00:00:00
abstract：:The activity of 28 cells located mainly in the secondary auditory cortex (A II) of awake squirrel-monkeys, was extracellularly recorded for periods of up to 6 h. Seven different species-specific vocalizations, which were repeatedly presented to the monkey, were used as auditory stimuli. Twenty-six cells responded, at ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239144
更新日期：1979-02-15 00:00:00
abstract：:The activity of the rat hindlimb during treadmill stepping was studied in normal adult rats and in rats in which cerebellar development was interfered with by early-postnatal focal X-irradiation. Based on cinematographic and electromyographic data from over 100 step cycles in 15 normal rats, correlations were made bet...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236145
更新日期：1980-01-01 00:00:00
abstract：:Stimulation of cutaneous foot afferents has been shown to evoke a facilitation of the tibialis anterior (TA) EMG-activity at a latency of 70-95 ms in the early and middle swing phase of human walking. The present study investigated the underlying mechanism for this facilitation. In those subjects in whom it was possib...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050600
更新日期：1999-01-01 00:00:00
abstract：:Many neurons in the deeper layers of the superior colliculus (SC) respond to multiple sensory inputs--visual, auditory, and somatic--as well as provide signals essential for saccadic eye movements to targets in different modalities. When the eyes and pinnae are in primary position, the neural map of auditory space is ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231709
更新日期：1995-01-01 00:00:00
abstract：:Unilateral lesions of the right superior colliculus (SC) were made in hamsters on the day after birth. In order to quantify the extent of abnormal innervation by left eye fibers in the diencephalon and midbrain, the left eye was removed on postnatal day 12 or 36, and after an appropriate survival time, the brains were...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00406608
更新日期：1988-01-01 00:00:00
