Humoral immunity in measles infection: a critical factor?

abstract：:Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, with increasing incidence and prevalence in the last one-half century. IBD patients suffer from autonomic vagal neuropathy and nerve dysfunction, with deficiency of acetylcholine in inflamed mucosa. Recent studies showed that death of enteric neuron ...

journal_title：Medical hypotheses

authors： Guo Y,Lu N,Bai A

更新日期：2012-11-01 00:00:00

abstract：:Bacteria initiated peri-implantitis can lead to bone destruction around a dental implant, modifying its surface and preventing re-osseointegration. Consequently, all available methods for treating periimplantitis have disappointing long-term results. Implant failure will lead to loss of the prosthetic reconstruction a...

journal_title：Medical hypotheses

authors： Chaushu L,Shabat R,Gadyukov A,Chaushu G

更新日期：2018-12-01 00:00:00

abstract：:Styrene is one of the most important plastic monomers worldwide. Styrene-7,8-oxide (SO), the major in-vivo metabolite of styrene, is classified as probably carcinogenic to humans and carcinogenic in rodents. Biological monitoring of exposure to styrene is usually carried out by determination of mandelic acid and pheny...

journal_title：Medical hypotheses

authors： Marczynski B,Peel M,Baur X

更新日期：2000-04-01 00:00:00

abstract：:The repair and reconstruction of tissue defects and organ loss are severe problems, and many patients are eager to find avenues to these matters. Up until now, the number of methods used to repair tissue defects has increased, but all of these have their own advantages and inconveniences, and do not seem to have been ...

journal_title：Medical hypotheses

authors： Yang M,Liu L

更新日期：2008-01-01 00:00:00

abstract：:Juvenile nasopharyngeal angiofibroma (JNA) is the most common benign tumor of the nasopharynx. For reasons unknown, this tumor is found almost always in male population. However, site of origin of JNA is still an enigma. Previously, JNA was considered to arise from the superior aspect of sphenopalatine foramen. Over l...

journal_title：Medical hypotheses

authors： Kairo AK,Kumar R,Sharma SC

更新日期：2020-11-01 00:00:00

abstract：:The globally increasing incidences of Type 1 diabetes (T1DM) and Type 2 diabetes (T2DM) can have a common background. If challenged by the contemporary high level of nutritional glucose stimulation, the β-cells in genetically predisposed individuals are at risk for damage which can lead to the diseases. The fat to car...

journal_title：Medical hypotheses

authors： Sjöblad S

更新日期：2019-04-01 00:00:00

abstract：:In the recent hypothesis that hair loss might be a manifestation of metabolic abnormalities particularly hyperglicemia. It has been reported various environmental risk factors affecting hair loss. There is growing evidence on the relationship between prediabetes and worse metabolic profile. However, there are few stud...

journal_title：Medical hypotheses

authors： Cakir E

更新日期：2012-12-01 00:00:00

abstract：:Current tuberculosis control measures are focused on the prompt detection and treatment of active tuberculosis. Despite the measured success of this strategy, tuberculosis continues to be a public health issue of major significance around the world. This unwanted situation suggests the need to expand our control effor...

journal_title：Medical hypotheses

authors： Mao F,Chen T,Zhao Y,Zhang C,Bai B,Zhao S,Xu Z,Shi C

更新日期：2011-07-01 00:00:00

abstract：:Colic is generally defined as excessive crying in early infancy and can have negative consequences on the infant as well as on the infant's family life. Excessive crying can result in escalating parental stress levels, abusive caregiver response, increased risk of shaken baby syndrome and parental postpartum depressio...

journal_title：Medical hypotheses

authors： Jordan GJ

更新日期：2014-09-01 00:00:00

abstract：:The mechanisms of fibroproliferation disease (FPD) of the skin, such as keloids and hypertrophic scars, are still unknown. Since mechanical stress appears to be an important factor for FPD generation, we have studied the intervening factors that connect mechanical stress with keloid and scar formation. Hence, we intro...

journal_title：Medical hypotheses

authors： Akaishi S,Ogawa R,Hyakusoku H

更新日期：2008-01-01 00:00:00

abstract：:Parkinson's disease (PD) is a long-term degenerative disease that primarily affects the motor system of the central nervous system. This disease is difficult to diagnose and is one of the common diseases in the public. In this paper, we have proposed a novel data sampling method for the classification of Parkinson dis...

journal_title：Medical hypotheses

authors： Polat K,Nour M

更新日期：2020-03-16 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a severe, occlusive, thrombotic microangiopathy characterized by a systemic platelet aggregation, organ ischemia, profound thrombocytopenia and erythrocyte fragmentation. Recent observations have documented that a deficiency of a von Willebrand factor (VWF)-cleaving proteas...

journal_title：Medical hypotheses

authors： Franchini M

更新日期：2005-01-01 00:00:00

abstract：:Cystic fibrosis-related diabetes (CFRD) has emerged in the last thirty years as a critical complication of cystic fibrosis (CF) and is present in about 15% of CF patients with increasing prevalence with age approaching 50 for over 30 year olds. The mechanism of diabetes development in this group of patients is not ver...

journal_title：Medical hypotheses

authors： Ali BR

更新日期：2009-01-01 00:00:00

abstract：:A five-step hypothesis on the pathogenesis of Hodgkin's disease (HD) is presented. Weak immune suppressor activity gives a predisposition for the development of the disease, after which a non-specific immune stimulation can initiate a self-perpetuating uncontrolled stimulation between interdigitating cells (IDCs), mac...

journal_title：Medical hypotheses

authors： Zwitter M

更新日期：1984-12-01 00:00:00

abstract：:The author presents evidence from published papers of research done by numerous investigators that Multiple Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antig...

journal_title：Medical hypotheses

authors： Eidinoff H

更新日期：1988-06-01 00:00:00

abstract：:Breast cancer associated with pregnancy is defined as the one in which the diagnosis is made in a pregnancy or within one year of delivery. Breast cancer is the second most common malignancy during pregnancy and it is generally considered to have a worse prognosis than the one that is not associated with pregnancy. Th...

journal_title：Medical hypotheses

authors： Michel RM,Aguilar JL,Arrieta O

更新日期：2007-01-01 00:00:00

abstract：:Idiopathic intracranial hypertension (IHH or pseudotumor cerebri) is an uncommon but important cause of headache, characterized by raised intracranial pressure (ICP) in the absence of infection and intracranial pathology on neuroimaging. Lumbar puncture (LP) is usually contra-indicated in situations where the ICP is s...

journal_title：Medical hypotheses

authors： Salman M

更新日期：1999-10-01 00:00:00

abstract：:Cocaine is one of the principal drugs of abuse. Although impressive advances have been made, unanswered questions remain concerning mechanism of toxicity and addiction. Discussion of action mode usually centers on receptor binding and enzyme inhibition, with limited attention to events at the molecular level. This rev...

journal_title：Medical hypotheses

authors： Kovacic P

更新日期：2005-01-01 00:00:00

abstract：:Dupuytren's disease is a pathological condition of the palmar fascia characterized by the formation of contractile disease cords that result in permanent finger contracture. This condition is believed to progress from a myofibroblast-rich nodule in the early clinical stages of the disease to a contractile disease cord...

journal_title：Medical hypotheses

authors： Vi L,Gan BS,O'Gorman DB

更新日期：2010-03-01 00:00:00

abstract：:Optic neuropathy is an invaliding pathology with diverse clinical manifestation and varying causes. Current understanding of etiopathological aspects of optical neuropathy does not provide an effective treatment protocol. In this article we discuss existing treatment methods, and their effectiveness, evaluated dependi...

journal_title：Medical hypotheses

authors： Shkarubo AN,Nikolenko VN,Velichko AY,Sinelnikov MY

更新日期：2020-10-01 00:00:00

abstract：:Initiation and development of atherosclerosis has largely been attributed to irregular shear stress patterns and values, in the current literature. Abnormalities such as low shear stress, reversing and oscillatory shear force patterns, as well as temporal variations of shear stress are the most cited factors. However,...

journal_title：Medical hypotheses

authors： Anssari-Benam A,Korakianitis T

更新日期：2013-08-01 00:00:00

abstract：:An association between Alzheimer's Disease (AD) and low CSF and serum vitamin B12 (B12) has recently been described (1, 2, 3). This is apparently independent of nutritional intake (4). It has been suggested that such patients may exhibit an atypical form of cobalamin deficiency (3, 4). It is therefore proposed that th...

journal_title：Medical hypotheses

authors： McCaddon A,Kelly CL

更新日期：1992-03-01 00:00:00

abstract：:Cancer and other diseases may be a natural biological event, the activities of which may be dependent on the constitution of the individual. Where fetal and embryonic cells are not diseased or faulty or defective, they may be useful as therapies against cancer and other diseases. ...

journal_title：Medical hypotheses

authors： Caesar G

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Bipolar disorder (BD) is characterized by recurrent episodes of mood dysregulations and depression is considered as the most frequent form of relapse. However, there is some evidence that in tropical countries, the course might be different with fewer depressive episodes. This study aims to examine the frequ...

journal_title：Medical hypotheses

authors： Narayanaswamy JC,Moily N,Kubendran S,Reddy YC,Jain S

更新日期：2014-09-01 00:00:00

abstract：:The goal in the treatment of osteonecrosis of the femoral head is to preserve, not replace, the femoral head. Although many methods have been proposed, none has proved completely satisfactory. Cellular mediators as a supplement to bone grafting and decompression is an attractive approach to this problem because it com...

journal_title：Medical hypotheses

authors： Yuan B,Liu Z

更新日期：2007-01-01 00:00:00

abstract：:Hypertension has become a large burden of global development, but the mechanisms of it have still not been well elucidated. Increased contractility of vascular smooth cells induced by the overactivity of neurohormonal system or stress is one of the main and popular explanations until now. Smoothelin-B, recognized as t...

journal_title：Medical hypotheses

authors： Li SH,Hui RT

更新日期：2009-07-01 00:00:00

abstract：:For reasons that are not known, the incidence of stomach cancer is declining in most countries. In contrast, cancer of the gastric remnant after partial gastrectomy for peptic ulcer disease seems to be increasing. "Stump cancer" has been claimed to be a separate disease entity and has recently been mentioned as an iat...

journal_title：Medical hypotheses

authors： Domellöf L

更新日期：1979-04-01 00:00:00

abstract：:The terminology of cerebellar ataxias encompasses a variety of sporadic and inherited debilitating diseases. Patients exhibit disabling deficits such as dysmetria, kinetic tremor and ataxia of stance/gait. We are currently lacking effective treatments in degenerative cerebellar ataxias. Animal models of cerebellar dis...

journal_title：Medical hypotheses

authors： Manto M,Ben Taib NO

更新日期：2008-01-01 00:00:00

abstract：:Despite the widespread use of antidepressant medication, there are no signs that the burden of depression and suicide is decreasing in the industrialised world. This is generating mounting scepticism on the effectiveness of this class of drugs as an approach for the treatment of mood disorders. These doubts are also f...

journal_title：Medical hypotheses

authors： Procopio M

更新日期：2005-01-01 00:00:00

abstract：:Growing evidences suggest a link between normal tension glaucoma (NTG) and Alzheimer's disease (AD). Both of them are progressive neurodegenerative disorders. Recently researches provide a clue that optineurin may be a new common underlying risk factor involved in NTG and AD. OPTINEURIN (OPTN) gene coding for "optineu...

journal_title：Medical hypotheses

authors： Liu YH,Tian T

更新日期：2011-10-01 00:00:00