Predicting pattern formation in embryonic stem cells using a minimalist, agent-based probabilistic model.

abstract：:A conductive, uniform, and ultra-smooth flexible transparent composite film is produced by embedding silver nanowires (AgNWs) into poly(vinyl-butyral) (PVB) without pressure or high-temperature annealing. The adhesion of AgNWs was greatly improved by embedding them in PVB, and surface roughness and sheet resistance (R...

journal_title：Scientific reports

authors： Lee DJ,Oh Y,Hong JM,Park YW,Ju BK

更新日期：2018-09-21 00:00:00

abstract：:Dopamine is an important neurotransmitter that plays a key role in a wide range of both locomotive and cognitive functions in humans. Disturbances on the dopaminergic system cause, among others, psychosis, Parkinson's disease and Huntington's disease. Antipsychotics are drugs that interact primarily with the dopamine ...

journal_title：Scientific reports

authors： Goode-Romero G,Winnberg U,Domínguez L,Ibarra IA,Vargas R,Winnberg E,Martínez A

更新日期：2020-12-09 00:00:00

abstract：:Studies investigating association of depression with overall survival (OS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) yielded conflicting results. A nationwide cohort study, which included all adult patients [n = 7,170; depression group, 13.3% (N = 956); non-depression group, 86.7% (N = 6,214...

journal_title：Scientific reports

authors： Wang SM,Park SS,Park SH,Kim NY,Kang DW,Na HR,Lee JW,Han S,Lim HK

更新日期：2020-09-17 00:00:00

abstract：:This study was performed to compare the area of the foveal avascular zone (FAZ-area) obtained by three optical coherence tomography angiography (OCTA) instruments. This was a cross-sectional, non-interventional study of twenty-seven healthy right eyes. The superficial and deep FAZ-area was measured manually with three...

journal_title：Scientific reports

authors： Shiihara H,Sakamoto T,Yamashita T,Kakiuchi N,Otsuka H,Terasaki H,Sonoda S

更新日期：2017-08-29 00:00:00

abstract：:At the present study, a one-dimensional model for the flat sheet direct contact membrane distillation (DCMD) for desalination purposes is proposed. Flows and membrane properties have been estimated by appropriate temperature-dependent correlations. Results show that the numerical model is in a very good agreement with...

journal_title：Scientific reports

authors： Keshavarzzadeh AH

更新日期：2020-10-08 00:00:00

abstract：:RNA-sequencing has become the gold standard for whole-transcriptome gene expression quantification. Multiple algorithms have been developed to derive gene counts from sequencing reads. While a number of benchmarking studies have been conducted, the question remains how individual methods perform at accurately quantify...

journal_title：Scientific reports

authors： Everaert C,Luypaert M,Maag JLV,Cheng QX,Dinger ME,Hellemans J,Mestdagh P

更新日期：2017-05-08 00:00:00

abstract：:Microalgae identification is extremely difficult. The efficiency of DNA barcoding in microalgae identification involves ideal gene markers and approaches employed, which however, is still under the way. Although Scenedesmus has obtained much research in producing lipids its identification is difficult. Here we present...

journal_title：Scientific reports

authors： Zou S,Fei C,Wang C,Gao Z,Bao Y,He M,Wang C

更新日期：2016-11-09 00:00:00

abstract：:DEMETER-like DNA glycosylases (DMLs) initiate the base excision repair-dependent DNA demethylation to regulate a wide range of biological processes in plants. Six putative SmDML genes, termed SmDML1-SmDML6, were identified from the genome of S. miltiorrhiza, an emerging model plant for Traditional Chinese Medicine (TC...

journal_title：Scientific reports

authors： Li J,Li C,Lu S

更新日期：2018-05-08 00:00:00

abstract：:We developed a novel, erythropoietin-derived, non-erythropoiesis, cyclic helix B peptide (CHBP) that displays potent renoprotection against acute kidney injury (AKI). To determine the mechanism of CHBP-mediated protection, we investigated the proteomic profile of mice treated with CHBP in a kidney ischemia-reperfusion...

journal_title：Scientific reports

authors： Yang C,Liu J,Li L,Hu M,Long Y,Liu X,Zhu T,Huang X,Zhao S,Liu S,Rong R

更新日期：2015-12-10 00:00:00

abstract：:Stroke is one of the main causes of human disabilities. Experimental observations indicate that several mechanisms are activated during the recovery of functional activity after a stroke. Here we unveil how the brain recovers by explaining the role played by three mechanisms: Plastic adaptation, hyperexcitability and ...

journal_title：Scientific reports

authors： Berger D,Varriale E,van Kessenich LM,Herrmann HJ,de Arcangelis L

更新日期：2019-11-01 00:00:00

abstract：:The family of materials defined as ZrSiX (X = S, Se, Te) has been established as Dirac node-line semimetals, and subsequent study is urgent to exploit the promising applications of unusual magnetoresistance (MR) properties. Herein, we systematically investigated the anisotropic MR in the newly-discovered Dirac node-li...

journal_title：Scientific reports

authors： Pan H,Tong B,Yu J,Wang J,Fu D,Zhang S,Wu B,Wan X,Zhang C,Wang X,Song F

更新日期：2018-06-19 00:00:00

abstract：:Light, as the energy source in photosynthesis, is essential for plant growth and development. Extended darkness causes dramatic gene expression changes. In this study, we applied DNase-seq (DNase I hypersensitive site sequencing) to study changes of chromatin accessibility in euchromatic and heterochromatic regions un...

journal_title：Scientific reports

authors： Liu Y,Zhang W,Zhang K,You Q,Yan H,Jiao Y,Jiang J,Xu W,Su Z

更新日期：2017-06-22 00:00:00

abstract：:Graphite pencil stroked electrodes for paper-based Microfluidic devices are gaining immense attention due to their electrochemical properties, cost efficiency, and ease-of-use. However, their widespread use has been hindered by the challenges associated with their manual fabrication such as non-uniformity in graphite ...

journal_title：Scientific reports

authors： Rao LT,Rewatkar P,Dubey SK,Javed A,Goel S

更新日期：2020-07-15 00:00:00

abstract：:Cysteine based silver-gold nanocomposite (Cys/Ag-Au NCz) was synthesized, this was followed by its characterization using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Ultraviolet-visible spectroscopy (UV-Vis), Scanning electron microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDAX), ...

journal_title：Scientific reports

authors： Basik M,Mobin M,Shoeb M

更新日期：2020-01-14 00:00:00

abstract：:The current economics of the fish protein industry demand rapid, accurate and expressive prediction algorithms at every step of protein production especially with the challenge of global climate change. This help to predict and analyze functional and nutritional quality then consequently control food allergies in hype...

journal_title：Scientific reports

authors： Elaziz MA,Hemdan AM,Hassanien A,Oliva D,Xiong S

更新日期：2017-09-07 00:00:00

abstract：:Malaria is a fatal disease that displays a spectrum of symptoms and severity, which are determined by complex host-parasite interactions. It has been difficult to study the effects of parasite strains on disease severity in human infections, but the mechanisms leading to specific disease phenotypes can be investigated...

journal_title：Scientific reports

authors： Lacerda-Queiroz N,Riteau N,Eastman RT,Bock KW,Orandle MS,Moore IN,Sher A,Long CA,Jankovic D,Su XZ

更新日期：2017-09-05 00:00:00

abstract：:Hedgehog interacting protein (Hhip) is essential for islet formation and beta-cell proliferation during pancreatic development; abnormally elevated Hhip expression has been linked to human pancreatitis. Here, we investigate the role of Hhip in modulating insulin secretion in adult Hhip mice (Hhip +/- vs. Hhip+/+) fed ...

journal_title：Scientific reports

authors： Nchienzia H,Liao MC,Zhao XP,Chang SY,Lo CS,Chenier I,Ingelfinger JR,Chan JSD,Zhang SL

更新日期：2019-08-01 00:00:00

abstract：:The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8-10 mm), Grade C (5-8 mm), and Grade D (< 5 mm, normal). To identify the threshold size for E-...

journal_title：Scientific reports

authors： He L,Sun Y,Huang G

更新日期：2021-01-19 00:00:00

abstract：:The Italian hare (Lepus corsicanus) is endemic to Central-Southern Italy and Sicily, classified as vulnerable due to habitat alterations, low density and fragmented populations and ecological competition with the sympatric European hare (Lepus europaeus). Despite this status, only few and local studies have explored i...

journal_title：Scientific reports

authors： Buglione M,Petrelli S,de Filippo G,Troiano C,Rivieccio E,Notomista T,Maselli V,di Martino L,Carafa M,Gregorio R,Latini R,Fortebraccio M,Romeo G,Biliotti C,Fulgione D

更新日期：2020-08-04 00:00:00

abstract：:Surfaces with reversible wettability have broad applications but remain challenging since the switching process is usually energy intensive and complex. In this paper, a pyramid shaped Cu2S film with hierarchical micro/nanostructures is formed on a commercial copper mesh. This film is formed by a spontaneous redox sul...

journal_title：Scientific reports

authors： Xu S,Sheng R,Cao Y,Yan J

更新日期：2019-08-28 00:00:00

abstract：:To identify novel phenotypic associations related to Cytochrome P450 Family 2 Subfamily A Member 6 (CYP2A6), we investigated the human phenome in a total of 11,271 individuals. Initially, we conducted a phenome-wide association study in 3,401 nicotine-exposed elderly subjects considering 358 phenotypic traits. We iden...

journal_title：Scientific reports

authors： Polimanti R,Jensen KP,Gelernter J

更新日期：2017-04-21 00:00:00

abstract：:The use of nanocarriers composed of polyethylene glycol- and polyvinyl alcohol-coated vesicles encapsulating active molecules in place of conventional chemotherapy drugs can reduce many of the chemotherapy-associated challenges because of the increased drug concentration at the diseased area in the body. The present s...

journal_title：Scientific reports

authors： Ebadi M,Bullo S,Buskara K,Hussein MZ,Fakurazi S,Pastorin G

更新日期：2020-12-09 00:00:00

abstract：:Recent advances in genetic analyses have significantly refined human type 1 diabetes (T1D) associated loci. The goal of such effort is to identify the causal genes and have a complete understanding of the molecular pathways that independently or interactively influence cellular processes leading to the destruction of ...

journal_title：Scientific reports

authors： Chen YG,Ciecko AE,Khaja S,Grzybowski M,Geurts AM,Lieberman SM

更新日期：2020-07-21 00:00:00

abstract：:Symbiodinium is best-known as the photosynthetic symbiont of corals, but some clades are symbiotic in other organisms or include free-living forms. Identifying similarities and differences among these clades can help us understand their relationship with corals, and thereby inform on measures to manage coral reefs in ...

journal_title：Scientific reports

authors： González-Pech RA,Ragan MA,Chan CX

更新日期：2017-11-03 00:00:00

abstract：:Macroscopic rhythms are often signatures of healthy functioning in living organisms, but they are still poorly understood on their microscopic bases. Globally interacting oscillators with heterogeneous couplings are here considered. Thorough theoretical and numerical analyses indicate the presence of multiple phase tr...

journal_title：Scientific reports

authors： Qiu T,Bonamassa I,Boccaletti S,Liu Z,Guan S

更新日期：2018-08-28 00:00:00

abstract：:Predicting the occurrence of ventricular tachyarrhythmia (VTA) in advance is a matter of utmost importance for saving the lives of cardiac arrhythmia patients. Machine learning algorithms have been used to predict the occurrence of imminent VTA. In this study, we used a one-dimensional convolutional neural network (1-...

journal_title：Scientific reports

authors： Taye GT,Hwang HJ,Lim KM

更新日期：2020-04-21 00:00:00

abstract：:Transgenic sheep can be used to achieve genetic improvements in breeds and as an important large-animal model for biomedical research. In this study, we generated a TALEN plasmid specific for ovine MSTN and transfected it into fetal fibroblast cells of STH sheep. MSTN biallelic-KO somatic cells were selected as nuclea...

journal_title：Scientific reports

authors： Li H,Wang G,Hao Z,Zhang G,Qing Y,Liu S,Qing L,Pan W,Chen L,Liu G,Zhao R,Jia B,Zeng L,Guo J,Zhao L,Zhao H,Lv C,Xu K,Cheng W,Li H,Zhao HY,Wang W,Wei HJ

更新日期：2016-09-22 00:00:00

abstract：:Motility dysfunction is present not only during bowel obstruction (BO), but after obstruction is resolved. Previous studies found that lumen distension associated mechano-transcription of COX-2 and production of PGE2 in gut smooth muscle cells (SMC) account for motility dysfunction during obstruction. We hypothesized ...

journal_title：Scientific reports

authors： Lin YM,Fu Y,Hegde S,Tang Y,Radhakrishnan R,Shi XZ

更新日期：2018-06-11 00:00:00

abstract：:We developed a virus-like particle (VLP)-based therapeutic vaccine against angiotensin II receptor type 1, ATR-AP205-001, which could significantly reduce the blood pressure and protect target organs of hypertensive animals. In this study, we focused on the immunological effect and safety of the VLP-based vaccine. By ...

journal_title：Scientific reports

authors： Hu X,Deng Y,Chen X,Zhou Y,Zhang H,Wu H,Yang S,Chen F,Zhou Z,Wang M,Qiu Z,Liao Y

更新日期：2017-10-03 00:00:00

abstract：:Epilepsy is one of the most common neurological disorders and the administration of antiepileptic drugs (AEDs) is the most common treatment. Although there are more than 15 AEDs available, a third of epilepsy patients remain refractory to available drugs, so novel effective drugs are needed. Here, we found that DV21, ...

journal_title：Scientific reports

authors： Xu M,Sun P,Zhang Y,Yang CH,Wei X,Ma XX,Yang CR,Ni KM,Zhang YJ,Li XM

更新日期：2017-05-10 00:00:00