Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Jikomes N,Zoorob Mdoi
10.1038/s41598-020-69680-xsubject
Has Abstractpub_date
2020-08-27 00:00:00pages
14406issue
1issn
2045-2322pii
10.1038/s41598-020-69680-xjournal_volume
10pub_type
已发布勘误abstract::Daily life stress is an omnipresent phenomenon in modern society. Research has linked prolonged activation of the hypothalamic-pituitary-adrenal axis to psychiatric and somatic diseases. Everyday stressors substantially contribute to these health risks. Despite the notion that the physiological stress response is high...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33708-0
更新日期:2018-10-18 00:00:00
abstract::New treatments for oropharyngeal gonorrhoea are required to address rising antimicrobial resistance. We aimed to examine the efficacy of a 14-day course of mouthwash twice daily compared to standard treatment (antibiotic) for the treatment of oropharyngeal gonorrhoea. The OMEGA2 trial was a parallel-group and open-lab...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76184-1
更新日期:2020-11-09 00:00:00
abstract::Most complex systems are intrinsically dynamic in nature. The evolution of a dynamic complex system is typically represented as a sequence of snapshots, where each snapshot describes the configuration of the system at a particular instant of time. This is often done by using constant intervals but a better approach wo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39713
更新日期:2016-12-22 00:00:00
abstract::The main feature of the present numerical model is to explore the behavior of Maxwell nanoliquid moving within two horizontal rotating disks. The disks are stretchable and subjected to a magnetic field in axial direction. The time dependent characteristics of thermal conductivity have been considered to scrutinize the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74096-8
更新日期:2020-10-13 00:00:00
abstract::Understanding the excited-state dynamics in perovskite photovoltaics is necessary for progress in these materials, but changes in dynamics depending on the fabrication processes used for perovskite photoactive layers remain poorly characterised. Here we report a comparative study on femtosecond transient absorption (T...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16654-1
更新日期:2017-11-28 00:00:00
abstract::Dermal papilla cells (DPCs) are important components of hair follicles and play a critical role in hair follicle development. However, the mechanisms by which DPCs induce hair follicle development remain unclear. In the present study, we identified the mitotic arrest deficient protein MAD2B as a modifier of DPCs. Over...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10350-w
更新日期:2017-09-15 00:00:00
abstract::In kidney disease, higher circulating levels of the mineral-regulating hormone fibroblast growth factor (FGF)-23 are predictive of disease progression but direct pathogenic effects on the kidney are unknown. We sought evidence of local renal synthesis in response to unilateral ureteric obstruction in the mouse, and pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02709-w
更新日期:2017-06-13 00:00:00
abstract::Much of atmospheric water originates from transpiration, the process by which plants release H2O from pores, known as stomata, that simultaneously intake CO2 for photosynthesis. Controlling stomatal aperture can regulate the extent of water transport in response to dynamic environmental factors including osmotic stres...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32394
更新日期:2016-08-31 00:00:00
abstract::MCM7, a subunit of mini-chromosome maintenance proteins (MCM) complex, plays an important role in initiating DNA replication during the G1 phase and extending DNA strands during the S phase. Here, we demonstrated that MCM7 is not only sustained but maintains association with chromatin during M phase. Remarkably, MCM7 ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03148-3
更新日期:2017-06-06 00:00:00
abstract::Expression profiling of multiple microRNAs (miRNAs) generally provides valuable information for understanding various biological processes. Thus, it is necessary to develop a sensitive and accurate miRNA assay suitable for multiplexing. Isothermal exponential amplification reaction (EXPAR) has received significant int...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11895-6
更新日期:2017-09-12 00:00:00
abstract::Species are chronically exposed to ionizing radiation, a natural phenomenon which can be enhanced by human activities. The induced toxicity mechanisms still remain unclear and seem depending on the mode of exposure, i.e. acute and chronic. To better understand these phenomena, studies need to be conducted both at the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29033-1
更新日期:2018-07-27 00:00:00
abstract::The distribution of corals in Japan covers a wide range of latitudes, encompassing tropical to temperate zones. However, coral communities in temperate zones contain only a small subset of species. Among the parameters that determine the distribution of corals, temperature plays an important role. We tested the resili...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18467
更新日期:2015-12-18 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-42889-1
更新日期:2019-06-10 00:00:00
abstract::Yinchenhao decoction (YCHD), comprising Yinchenhao (Artemisiae Scopariae Herba), Zhizi (Gardeniae Fructus) and Dahuang (Radix Rhei et Rhizoma), is widely used for treating various diseases. We aimed to investigate the bile acid metabolic mechanism of YCHD in dimethylnitrosamine (DMN)-induced liver fibrosis model. Rats...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33669-4
更新日期:2018-10-18 00:00:00
abstract::Although cooperation is central to the organisation of many social systems, relatively little is known about cooperation in situations of collective emergency. When groups of people flee from a danger such as a burning building or a terrorist attack, the collective benefit of cooperation is important, but the cost of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33417
更新日期:2016-09-15 00:00:00
abstract::Neurodevelopmental changes occur with asymmetric hearing loss, limiting binaural/spatial hearing and putting children at risk for social and educational challenges. These deficits may be mitigated by providing bilateral hearing in children through auditory prostheses. Effects on speech perception and spatial hearing w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31546-8
更新日期:2018-09-04 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-35358-8
更新日期:2018-11-16 00:00:00
abstract::Aerogels have numerous applications due to their high surface area and low densities. However, creating aerogels from a large variety of materials has remained an outstanding challenge. Here, we report a new methodology to enable aerogel production with a wide range of materials. The method is based on the assembly of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00849
更新日期:2012-01-01 00:00:00
abstract::The aim of this study was to explore whether rotational three-dimensional (3D) visualization of optical coherence tomography angiography (OCTA) volume data may yield valuable information regarding diabetic retinal microaneurysm (MA) characteristics. In this retrospective, observational study, we collected data from 20...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53357-1
更新日期:2019-11-14 00:00:00
abstract::Accidental introduction through ballast water and biofouling are currently the main factors responsible for spreading non-indigenous species in the marine realm. In the Southwestern Atlantic, two scleractinian corals, Tubastraea coccinea and T. tagusensis, have been introduced by opportunistic colonization in 1980 and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50442-3
更新日期:2019-09-27 00:00:00
abstract::Vaginal microbiota is an important early source of bacterial colonization for newborns. However, only a few small studies have investigated the composition of vaginal microbiota during labor. In this work, we analyzed vaginal swabs collected at 36 weeks gestation and at the onset of labor from 256 women participating ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17972-0
更新日期:2017-12-14 00:00:00
abstract::Chronic hepatitis viral infection, alcoholic intoxication, and obesity cause liver fibrosis, which progresses to decompensated liver cirrhosis, a disease for which medical demands cannot be met. Since there are currently no approved anti-fibrotic therapies for established liver fibrosis, the development of novel modal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43298-0
更新日期:2019-05-02 00:00:00
abstract::To describe the rationale and surgical technique and compare the clinical effect of posterior percutaneous endoscopic cervical discectomy (PPECD) using the Delta system versus that of conventional PPECD (key-hole) surgery for the treatment of symptomatic cervical spondylotic radiculopathy (CSR). A retrospective analys...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67381-z
更新日期:2020-06-24 00:00:00
abstract::Stress and recovery from stress significantly affect interactions between the central nervous system, endocrine pathways, and the immune system. However, the influence of acute stress on circulating immune-endocrine mediators in humans is not well known. Using a double-blind, randomized study design, we administered a...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/srep23008
更新日期:2016-03-29 00:00:00
abstract::An important number of healthy and diseased tissues shows spatial variations in their metabolic capacities across the tissue. The liver is a prime example of such heterogeneity where the gradual changes in various metabolic activities across the liver sinusoid is termed as "zonation" of the liver. Here, we introduce t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27179-6
更新日期:2018-06-12 00:00:00
abstract::In this paper, we investigate the high frequency performance of Co90Zr10/SiO2/Co90Zr10 trilayers. It is demonstrated that the in-plane isotropic microwave performance is theoretically derived from the solution of the Landau-Lifshitz-Gilbert equation and experimentally achieved in that sandwich structured film. The val...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21327
更新日期:2016-02-17 00:00:00
abstract::Although diatoms have been extensively studied as bioreactors, only a limited number of efficient gene promoters are available. Therefore, the development of new endogenous promoters is important for the heterologous production of a variety of recombinant proteins. Herein, we identified the most abundant secreted prot...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45786-9
更新日期:2019-07-09 00:00:00
abstract::Rapid vertebrate diversity evaluation is invaluable for monitoring changing ecosystems worldwide. Wild blow flies naturally recover DNA and chemical signatures from animal carcasses and feces. We demonstrate the power of blow flies as biodiversity monitors through sampling of flies in three environments with varying h...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46758-9
更新日期:2019-07-22 00:00:00
abstract::Transforming growth factor-β (TGF-β) signaling plays a key role in progression and metastasis of HCC. This study was undertaken to gain the proof of concept of a small-molecule inhibitor of TGF-β type I receptor kinase, EW-7197 as a potent anti-cancer therapy for HCC. We identified tissue inhibitors of metalloproteina...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16492
更新日期:2015-11-09 00:00:00
abstract::A photovoltaic reactor was designed for artificial photosynthesis, based on the reactions involved in high energy hydrogen atoms, which were produced from water electrolysis. Water and CO2, under the conditions studied, were converted to oxalate (H2C2O4) and a polymer. This was the first time that the oxalates and oxa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03572
更新日期:2014-01-06 00:00:00