Abstract:
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journal_name
Sci Repjournal_title
Scientific reportsauthors
Paul F,Otte J,Schmitt I,Grande FDdoi
10.1038/s41598-018-35358-8subject
Has Abstractpub_date
2018-11-16 00:00:00pages
17229issue
1issn
2045-2322pii
10.1038/s41598-018-35358-8journal_volume
8pub_type
已发布勘误abstract::Obesity and inactivity are major risk factors of feline diabetes mellitus (FDM) and human type II diabetes mellitus (T2DM). In recent years, changes in the gut microbiota have been suggested as a contributing factor to T2DM. Whether the gut microbiota (GM) composition plays a role in FDM remains unknown. The aim of th...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究
doi:10.1038/s41598-019-41195-0
更新日期:2019-03-18 00:00:00
abstract::When lightning strikes soil, it may generate a cylindrical tube of glass known as a fulgurite. The morphology of a fulgurite is ultimately a consequence of the energy of the lightning strike that formed it, and hence fulgurites may be useful in elucidating the energy distribution frequency of cloud-to-ground lightning...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30586
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abstract::Grain yield is a complicated trait, which is highly associated with biomass productivity. The cell wall is a central element of biomass, and its biogenesis contributes to plant architecture and development. However, the genetic link between cell-wall property and grain yield is largely unclear. Here, we report on iden...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12903-5
更新日期:2017-10-02 00:00:00
abstract::Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with diverse clinical presentation and outcome. Bio-clinical prognostic models including oncogene expression and cell-of-origin phenotyping has been developed, however, approximately 30% of all patients still die from their disease, illustrating the need...
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pub_type: 杂志文章
doi:10.1038/s41598-018-36680-x
更新日期:2019-01-23 00:00:00
abstract::Endocannabinoids are small signaling lipids, with 2-arachidonoylglycerol (2-AG) implicated in modulating axonal growth and synaptic plasticity. The concept of short-range extracellular signaling by endocannabinoids is supported by the lack of trans-synaptic 2-AG signaling in mice lacking sn-1-diacylglycerol lipases (D...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02093
更新日期:2013-01-01 00:00:00
abstract::Staphylococcus lugdunensis is a commensal bacterium in humans and other animals that can cause serious infections. The aim of this research was to estimate the frequency of S. lugdunensis in pet cats and to characterize the S. lugdunensis isolates obtained. The prevalence of S. lugdunensis was 0.77% (4/523) in healthy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72395-8
更新日期:2020-09-22 00:00:00
abstract::Twirling is a technique widely used for converting arbitrary noise channels into Pauli channels in error threshold estimations of quantum error correction codes. It is vitally useful both in real experiments and in classical quantum simulations. Minimising the size of the twirling gate set increases the efficiency of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46722-7
更新日期:2019-08-02 00:00:00
abstract::Baroreflex dysfunction is a diffuse chronic condition that is expected to be followed by a profound loss of organization of BP and HR variability. Nevertheless, long-term effects of baroreflex withdrawal are still debated. Aim of our work was to study BP and HR changes long term after sino-aortic denervation (SAD). In...
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pub_type: 杂志文章
doi:10.1038/s41598-018-37970-0
更新日期:2019-02-04 00:00:00
abstract::We used Mendelian randomization to estimate the causal effects of the liver enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT), on diabetes and cardiovascular disease, using genetic variants predicting these liver enzymes at genome wide significance applied to exten...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38813
更新日期:2016-12-20 00:00:00
abstract::Glutamate is an indispensable neurotransmitter, triggering postsynaptic signals upon recognition by postsynaptic receptors. We questioned the phylogenetic position and the molecular details of when and where glutamate recognition arose in the glutamate-gated chloride channels. Experiments revealed that glutamate recog...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08558
更新日期:2015-02-24 00:00:00
abstract::This study investigated the variation characteristics of micro-topography during successive erosive stages of water erosion: splash erosion (SpE), sheet erosion (ShE), and rill erosion (RE). Micro-topography was quantified using surface elevation change, soil roughness (SR) and multifractal model. Results showed that ...
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pub_type: 杂志文章
doi:10.1038/s41598-018-21852-6
更新日期:2018-02-22 00:00:00
abstract::Sublingual immunization is emerging as an alternative to nasal immunization and induction of mucosal IgA responses. Using Bacillus anthracis edema toxin (EdTx) as an adjuvant, we previously showed that innate responses triggered after sublingual immunization could limit generation of IgA responses. We tested whether c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36370-8
更新日期:2019-01-24 00:00:00
abstract::Among patients with non-small cell lung cancer (NSCLC), best supportive care (BSC) is well-known to improve patient's quality of life and prolong survival. This study aimed to clarify (1) the decision-making factors of BSC alone and (2) the prognostic factors after selection of no further anticancer therapies. We retr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56431-w
更新日期:2019-12-27 00:00:00
abstract::Galvanic vestibular stimulation (GVS) can be applied to induce the feeling of directional virtual head motion by stimulating the vestibular organs electrically. Conventional studies used a two-pole GVS, in which electrodes are placed behind each ear, or a three-pole GVS, in which an additional electrode is placed on t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10168
更新日期:2015-05-11 00:00:00
abstract::The artificial earthquake of mb 6.1 related to the North Korea's sixth nuclear test occured at Mt. Mantap, North Korea on September 3, 2017. It was reported that a large and complex surface deformation was caused by the event. The surface deformation was composed of expansion of explosions, collapse, compaction and la...
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pub_type: 杂志文章
doi:10.1038/s41598-020-74957-2
更新日期:2020-10-20 00:00:00
abstract::EndMT has an important effect on metastasis and progression of tumor. This work will elucidate the effect of miR-494 on EndMT and development of HCC. Therefore, the differential miRNA expression among non-tumorous, para-tumorous and tumorous tissues was analyzed. Moreover, luciferase activities of SIRT3 3'UTR treated ...
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pub_type: 杂志文章
doi:10.1038/s41598-019-43731-4
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abstract::Prostaglandins (PGs) are hormone-like mediators in many physiological and pathological processes that are present in all vertebrates, in some terrestrial and aquatic invertebrates, and have also been identified in some macroalgae. They have recently been reported also in marine microalgae but their role as chemical me...
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pub_type: 杂志文章
doi:10.1038/s41598-020-61967-3
更新日期:2020-03-25 00:00:00
abstract::We study the spreading of cell aggregates deposited on adhesive substrates decorated with microparticles (MPs). A cell monolayer expands around the aggregate. The cells on the periphery of the monolayer take up the MPs, clearing the substrate as they progress and forming an aureole of cells filled with MPs. We study t...
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pub_type: 杂志文章
doi:10.1038/s41598-017-15665-2
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abstract::A reduction in the particle size is expected to improve the properties and increase the application potential of high-entropy alloys. Therefore, in this study, a novel sol-gel autocombustion technique was first used to synthesize high-entropy alloys. The average grain size of the prepared nanocrystalline CoCrCuNiAl hi...
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abstract::Central to intrinsic apoptosis signaling is the release of cytochrome c from mitochondria, which depends on the pro-apoptotic effector proteins Bax, Bak or Bok. These pore-forming effector proteins share four Bcl-2 homology (BH) domains, a functionally essential and conserved sequence of hydrophobic amino acids in the...
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pub_type: 杂志文章
doi:10.1038/s41598-019-48029-z
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abstract::The discovery of single-phase multiferroic materials and the understanding of coupling mechanisms between their spin and polarization is important from the point of view of next generation logic and memory devices. Herein we report the fabrication, dielectric, ferroelectric, piezo-response force microscopy, and magnet...
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pub_type: 杂志文章
doi:10.1038/s41598-020-59961-w
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abstract::The rat is an important model for liver regeneration. However, there is no in vitro culture system that can capture the massive proliferation that can be observed after partial hepatectomy in rats. We here describe the generation of rat liver stem cell lines. Rat liver stem cells, which grow as cystic organoids, were ...
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doi:10.1038/srep22154
更新日期:2016-02-26 00:00:00
abstract::Advanced colorectal cancer (CRC) remains a critical health care challenge worldwide. Various TGF-β superfamily members are important in colorectal cancer metastasis, but their signaling effects and predictive value have only been assessed in isolation. Here, we examine cross-regulation and combined functions of the tw...
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pub_type: 杂志文章
doi:10.1038/s41598-017-05907-8
更新日期:2017-07-17 00:00:00
abstract::The controlled preparation of Au nanoparticles (NPs) in the size range of 6 to 22 nm is explored in this study. The Au NPs were prepared by the reduction of tetrachloroauric acid using maltose in the presence of nonionic surfactant Tween 80 at various concentrations to control the size of the resulting Au NPs. With in...
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pub_type: 杂志文章
doi:10.1038/s41598-018-22976-5
更新日期:2018-03-15 00:00:00
abstract::Aedes aegypti is the primary vector for transmission of Dengue, Zika and chikungunya viruses. Previously it was shown that Dengue virus infection of the mosquito led to an in increased expression of the odorant binding protein 22 (AeOBP22) within the mosquito salivary gland and that siRNA mediated knockdown of AeOBP22...
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doi:10.1038/s41598-020-60242-9
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abstract::Antimicrobial resistant infections are a serious public health threat worldwide. Whole genome sequencing approaches to rapidly identify pathogens and predict antibiotic resistance phenotypes are becoming more feasible and may offer a way to reduce clinical test turnaround times compared to conventional culture-based m...
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doi:10.1038/s41598-017-18972-w
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abstract::Vertical mixing modulates nutrient dynamics in lakes. However, surface warming reduces the range of vertical mixing and the probability of full circulation events. Important consequences of reduced vertical mixing include the sequestration of phosphorus (P) within a stagnant zone and the promotion of oligotrophication...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69721-5
更新日期:2020-07-31 00:00:00