Genotypic analysis using a Y-chromosome-specific probe following bone marrow transplantation.

abstract：:In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%. This risk has been estimated to be 1-5.9% with hydroxyurea (HU) therapy. When compared with historical controls, the risk with use of HU does not appear to be statist...

journal_title：American journal of hematology

authors： Nand S,Stock W,Godwin J,Fisher SG

更新日期：1996-05-01 00:00:00

abstract：:Granulysin is a newly identified CTL/NK cell-related cytotoxic protein, which is secreted in both constitutive and Ca-dependent manner. To evaluate its significance in stem-cell transplantation (SCT), serum granulysin was measured by newly established ELISA method in 26 patients undergoing SCT (21 allogeneic and 5 aut...

journal_title：American journal of hematology

authors： Nagasawa M,Isoda T,Itoh S,Kajiwara M,Morio T,Shimizu N,Ogawa K,Nagata K,Nakamura M,Mizutani S

更新日期：2006-05-01 00:00:00

abstract：:Over a 36-month period, 46 consecutive Mexican mestizos with a clinical marker associated with a primary hypercoagulable state were prospectively assessed by searching for the sticky platelet syndrome (SPS), the activated protein C resistance (aPCR) phenotype, coagulation protein C activity and antigen, coagulation pr...

journal_title：American journal of hematology

authors： Ruiz-Argüelles GJ,López-Martínez B,Valdés-Tapia P,Gómez-Rangel JD,Reyes-Núñez V,Garcés-Eisele J

更新日期：2005-01-01 00:00:00

abstract：:Hereditary spherocytosis (HS) is due to different membrane protein defects (i.e., deficiency of spectrin and ankyrin, band 3, or band 4.2). In order to gain new insight into the relationships between band 3 function and proteins associated with the cytoskeleton, we studied erythrocyte anion transport activity in HS ch...

journal_title：American journal of hematology

authors： De Franceschi L,Olivieri O,Miraglia del Giudice E,Perrotta S,Sabato V,Corrocher R,Iolascon A

更新日期：1997-07-01 00:00:00

abstract：:A 69-year-old man with immunoblastic lymphadenopathy and autoimmune hemolytic anemia who had no previous exposure to blood products developed a severe febrile nonhemolytic transfusion reaction following the initial infusion of packed red blood cells. The reaction recurred with transfusion of packed red blood cells, bu...

journal_title：American journal of hematology

authors： Barnes HM,Poon MC,Huang ST,Conrad ME,Lin J,McGowan EI

更新日期：1983-02-01 00:00:00

abstract：:If a translocation is followed by loss of one of the two derivative chromosomes, the result is an unbalanced translocation, showing monosomy for the segments making up the lost derivative. We have found that in most unbalanced translocations, a third event takes place: a morphologically normal copy of one of the two t...

journal_title：American journal of hematology

authors： Pedersen B,Nørgaard JM,Pedersen BB,Clausen N,Rasmussen IH,Thorling K

更新日期：2000-07-01 00:00:00

abstract：:The levels of adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), lactic dehydrogenase (LDH), and LDH isoenzyme patterns (LD1 to LD5) have been measured in lymphocyte extract from 28 patients with B-chronic lymphocytic leukemia (B-CLL). The activities of ADA, PNP, and LDH have been correlated with two mo...

journal_title：American journal of hematology

authors： Vives Corrons JL,Rozman C,Pujades MA,Colomer D,Perez Vila E,Anegon I,Gallart T,Vives Puiggrós J,Viñolas N,Montserrat E

更新日期：1988-03-01 00:00:00

abstract：:We aimed to determine the survival benefits of chemotherapy (CT) added to radiotherapy (RT) in different risk groups of patients with early-stage extranodal nasal-type NK/T-cell lymphoma (ENKTCL), and to investigate the risk of postponing RT based on induction CT responses. A total of 1360 patients who received RT wit...

journal_title：American journal of hematology

authors： Qi SN,Yang Y,Zhang YJ,Huang HQ,Wang Y,He X,Zhang LL,Wu G,Qu BL,Qian LT,Hou XR,Zhang FQ,Qiao XY,Wang H,Li GF,Zhu Y,Cao JZ,Wu JX,Wu T,Zhu SY,Shi M,Xu LM,Yuan ZY,Su H,Song YQ,Zhu J,Hu C,Li YX

更新日期：2020-09-01 00:00:00

abstract：:Several histone deacetylase inhibitors (HDACi), including vorinostat, have been approved for the therapy of cutaneous T-cell lymphoma (CTCL). Emerging data suggest that HDACi may exert immune suppressive effects which would be disadvantageous for therapy of CTCL. We describe a patient with Sezary syndrome who was moni...

journal_title：American journal of hematology

authors： Stephen S,Morrissey KA,Benoit BM,Kim EJ,Vittorio CC,Nasta SD,Showe LC,Wysocka M,Rook AH

更新日期：2012-02-01 00:00:00

abstract：:The optimal treatment of advanced sporadic Burkitt lymphoma in adults is still a matter of debate. The salutary results of pediatric therapies did open the road for improving the adult outcome. Between May 1988 and March 2009, 71 consecutive patients-46 adults, 25 children-affected by Burkitt lymphoma/leukemia were tr...

journal_title：American journal of hematology

authors： Todeschini G,Bonifacio M,Tecchio C,Balter R,Carli G,Stefani PM,Adami F,Zamò A,Dei Tos AP,Marino F,Gherlinzoni F,Marradi P,Semenzato G,Pizzolo G

更新日期：2012-01-01 00:00:00

abstract：:Reverse transcription quantitative polymerase chain reaction (RTqPCR)is currently the most sensitive tool available for the routine monitoring of disease level in patients undergoing treatment for BCRABL1 associated malignancies. Considerable effort has been invested at both the local and international levels to stand...

journal_title：American journal of hematology

authors： Gerrard G,Mudge K,Foskett P,Stevens D,Alikian M,White HE,Cross NC,Apperley J,Foroni L

更新日期：2012-07-01 00:00:00

abstract：:Tumor cells of 14 cases of non-Hodgkin lymphomas and 2 cases of Hodgkin disease were tested for the presence of the transferrin receptor (CD71) by flow cytofluorimetry before 67gallium imaging. It appeared that expression of CD71 phenotype was closely related to the positivity of gallium scan before therapy. We feel t...

journal_title：American journal of hematology

authors： Feremans W,Bujan W,Neve P,Delville JP,Schandene L

更新日期：1991-03-01 00:00:00

abstract：:The occurrence of factor VIII inhibitors in non-hemophilic patients is a rare event with a potentially lethal outcome. Despite its infrequent occurrence, the association of this inhibitor with multiple autoimmune diseases is well recognized. We report the case of a patient with the recently described autoimmune lympho...

journal_title：American journal of hematology

authors： Fang BS,Sneller MC,Straus SE,Frenkel L,Dale JK,Rick ME

更新日期：2000-07-01 00:00:00

abstract：:Red blood cell (RBC) autoantibodies are a relatively uncommon cause of anemia. However, autoimmune hemolytic anemia (AIHA) must be considered in the differential diagnosis of hemolytic anemias, especially if the patient has a concomitant lymphoproliferative disorder, autoimmune disease, or viral or mycoplasmal infecti...

journal_title：American journal of hematology

authors： Gehrs BC,Friedberg RC

更新日期：2002-04-01 00:00:00

abstract：:Ticlopidine-induced aplastic anemia (TIAA) is considered very uncommon. We present two new cases, and we review 55 additional cases from the literature. The first case concerns a 70-year-old man who developed severe aplastic anemia 7 weeks after treatment with 500 mg of ticlopidine daily. The patient sustained a sever...

journal_title：American journal of hematology

authors： Symeonidis A,Kouraklis-Symeonidis A,Seimeni U,Galani A,Giannakoulas N,Fragopanagou E,Tiniakou M,Matsouka P,Zoumbos N

更新日期：2002-09-01 00:00:00

abstract：:Thalassemia is an inherited blood disorder that requires lifelong adherence to a complicated and burdensome medical regimen which could potentially impact emotional functioning of patients. The importance of understanding and promoting healthy emotional functioning is crucial not only to psychological well-being, but ...

journal_title：American journal of hematology

authors： Mednick L,Yu S,Trachtenberg F,Xu Y,Kleinert DA,Giardina PJ,Kwiatkowski JL,Foote D,Thayalasuthan V,Porter JB,Thompson AA,Schilling L,Quinn CT,Neufeld EJ,Yamashita R,Thalassemia Clinical Research Network.

更新日期：2010-10-01 00:00:00

abstract：:A common side effect of opioids is nausea and vomiting; however, the incidence in hospitalized patients receiving opioids for acute pain is unknown. We performed a retrospective study in adult patients with sickle cell disease admitted for an acute pain crisis during a six-month period to evaluate the incidence of nau...

journal_title：American journal of hematology

authors： Shord SS,Chew L,Villano J

更新日期：2008-03-01 00:00:00

abstract：:FIP1L1-PDGFRA-positive myeloid neoplasm with eosinophilia (F/P+ MN-eo) is a rare disease: robust epidemiological data are lacking and reported issues are scarce, of low sample-size and limited follow-up. Imatinib mesylate (IM) is highly efficient but no predictive factor of relapse after discontinuation has yet been i...

journal_title：American journal of hematology

authors： Rohmer J,Couteau-Chardon A,Trichereau J,Panel K,Gesquiere C,Ben Abdelali R,Bidet A,Bladé JS,Cayuela JM,Cony-Makhoul P,Cottin V,Delabesse E,Ebbo M,Fain O,Flandrin P,Galicier L,Godon C,Grardel N,Guffroy A,Hamidou M,

更新日期：2020-11-01 00:00:00

abstract：:Duvelisib (IPI-145), an oral, dual inhibitor of phosphoinositide-3-kinase (PI3K)-δ and -γ, was evaluated in a Phase 1 study in advanced hematologic malignancies, which included expansion cohorts in relapsed/refractory (RR) chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and treatment-naïve (TN) CLL...

journal_title：American journal of hematology

authors： O'Brien S,Patel M,Kahl BS,Horwitz SM,Foss FM,Porcu P,Jones J,Burger J,Jain N,Allen K,Faia K,Douglas M,Stern HM,Sweeney J,Kelly P,Kelly V,Flinn I

更新日期：2018-11-01 00:00:00

abstract：:The lupus anticoagulant may be accompanied by an acquired factor II deficiency and bleeding. We report on a patient with a lupus anticoagulant and factor II (Fll) deficiency responsive to Danazol. Acquired hypoprothrombinemia (FII) with the lupus anticoagulant (LA) may be accompanied by a hemorrhagic diathesis. A 64-y...

journal_title：American journal of hematology

authors： Williams S,Linardic C,Wilson O,Comp P,Gralnick HR

更新日期：1996-12-01 00:00:00

abstract：:Endothelin-1 (Et-1) is a vasoconstrictor produced by endothelial and vascular smooth muscle cells in response to hypoxia, which induces hypertrophy in cultured cardiac myocytes. We measured plasma Et-1 levels and left ventricular dimensions in 13 patients with sickle cell anemia (SCD) and in 12 African-American contro...

journal_title：American journal of hematology

authors： Werdehoff SG,Moore RB,Hoff CJ,Fillingim E,Hackman AM

更新日期：1998-07-01 00:00:00

abstract：:Neonatal alloimmune thrombocytopenia is an uncommon but important cause of thrombocytopenia in infants. Because of the severity of the thrombocytopenia, some of these infants will have intracranial hemorrhage with resultant long-term disability. Obstetricians and neonatologists have recommended delivery by caesarean s...

journal_title：American journal of hematology

authors： Burrows RF,Caco CC,Kelton JG

更新日期：1988-06-01 00:00:00

abstract：:By using Dexter-type long-term marrow cultures (D-LTMC), it has been shown previously that hematopoietic progenitor cells (HPC) from patients with aplastic anemia (AA) have a deficient proliferation in vitro. The studies reported to date, however, have focused exclusively on granulomonocytic progenitors and no informa...

journal_title：American journal of hematology

authors： Gómez-Morales E,Martinez-Jaramillo G,Sánchez-Valle E,Valencia-Plata I,Arana-Trejo RM,Castro MA,Pizzuto-Chávez J,Mayani H

更新日期：1998-10-01 00:00:00

abstract：:Fourteen patients, aged 65-85 years, with refractory (11) or relapsing (3) multiple myeloma were treated with a "protracted-sequential" protocol comprising vincristine 1-2 mg or vindesine 3 mg/M(2) (max. 5 mg) IVI over 4 hr on D1, prednisolone 40-50 mg PO D1-14, and melphalan 2-4 mg PO or cyclophosphamide 50-100 mg PO...

journal_title：American journal of hematology

authors： Manoharan A

更新日期：2000-09-01 00:00:00

abstract：:In this study we investigated the possible role of neutrophil (PMN) elastase and its natural inhibitor, alpha1-proteinase inhibitor (alpha1-PI) in the pathogenesis of the pseudoxanthoma elasticum (PXE)-like syndrome which is found in patients with homozygous beta-thalassemia. We studied 30 beta-thalassemia homozygotes...

journal_title：American journal of hematology

authors： Samarkos M,Aessopos A,Fragodimitri C,Karagiorga M,Kalotychou V,Voskaridou E,Kavouklis E,Loukopoulos D

更新日期：2000-02-01 00:00:00

abstract：:Celecoxib, a specific cyclooxygenase-2 (Cox-2) inhibitor, has been shown to possess antitumor activity in a variety of cancer cells. However, the antitumor activity of celecoxib in hematopoietic tumors, especially in chronic myeloid leukemia (CML), has not been well established. This study was designed to investigate ...

journal_title：American journal of hematology

authors： Zhang GS,Liu DS,Dai CW,Li RJ

更新日期：2006-04-01 00:00:00

abstract：:Monoclonal B-cell lymphocytosis (MBL) with normal lymphocyte counts is associated with decreased numbers of normal circulating B-cell subsets.Little is known about the distribution of normal lymphoid cells and their subsets in the peripheral blood (PB) of subjects with monoclonal B-cell lymphocytosis (MBL). In our stu...

journal_title：American journal of hematology

authors： Hauswirth AW,Almeida J,Nieto WG,Teodosio C,Rodriguez-Caballero A,Romero A,López A,Fernandez-Navarro P,Vega T,Perez-Andres M,Valent P,Jäger U,Orfao A,Primary Health Care Group of Salamanca for Study of MBL.

更新日期：2012-07-01 00:00:00

abstract：:A patient with congenital protein-C deficiency was treated with stanozolol for 8 weeks to increase circulating levels of protein C. A rise in protein C was achieved, accompanied by an increase in factor II, factor X, antithrombin III, and protein S; but at the 8th week the patient suffered a transient ischemia attack....

journal_title：American journal of hematology

authors： De Stefano V,Leone G,Teofili L,Ferrelli R,Pollari G,Antonini V,Bizzi B

更新日期：1988-10-01 00:00:00

abstract：:Little is known about the mechanisms explaining the wide variation in platelet counts (PLT) and other hematologic parameters in humans. We previously showed that the sex-based difference in hematocrit was associated with nucleotide variation in the erythropoietin receptor gene (EPOR). We sought to identify new polymor...

journal_title：American journal of hematology

authors： Zeng SM,Murray JC,Widness JA,Strauss RG,Yankowitz J

更新日期：2004-09-01 00:00:00

abstract：:This review focuses on the initial clinical descriptions and subsequent investigation of the syndrome of recurrent infections associated with neutrophil membrane glycoprotein deficiencies. Characterization of the missing group of three glycoprotein heterodimers and their role in adhesion-related neutrophil function is...

journal_title：American journal of hematology

authors： Styrt B

更新日期：1989-08-01 00:00:00