Combined assay of adenosine deaminase, purine nucleoside phosphorylase, and lactate dehydrogenase in the early clinical evaluation of B-chronic lymphocytic leukemia.

abstract：:Positron emission tomography-computed tomography (PET-CT) can identify bony lesions, assess disease burden, and detect extramedullary disease (EMD) in patients with multiple myeloma. We retrospectively reviewed records of patients who underwent PET-CT within 60 days of a new diagnosis (before therapy commenced) to ide...

journal_title：American journal of hematology

authors： Aljama MA,Sidiqi MH,Buadi FK,Lacy MQ,Gertz MA,Dispenzieri A,Dingli D,Muchtar E,Fonder AL,Hayman SR,Hobbs MA,Gonsalves WI,Warsame RM,Kourelis T,Hwa YL,Kapoor P,Kyle RA,Leung N,Go RS,Rajkumar SV,Kumar SK

更新日期：2018-12-01 00:00:00

abstract：:Genetic modifiers contribute to phenotypic variability in patients with sickle cell anemia (SCA). The influence of the bilirubin UDP-glucuronosyltransferase (UGT) 1A1 (TA)(n)TAA promoter polymorphism on bilirubin levels and gallbladder disease in SCA was examined using prospectively collected data from the Cooperative...

journal_title：American journal of hematology

authors： Carpenter SL,Lieff S,Howard TA,Eggleston B,Ware RE

更新日期：2008-10-01 00:00:00

abstract：:Aragon et al [4] reported that rat erythrocytes can be cross-linked and permeabilized without significant inactivation or alterations of several enzymes in the glycolytic pathway. If this is the case, in situ kinetic analysis of the red cell enzymes in normal human red cells and abnormal red cells associated with hemo...

journal_title：American journal of hematology

authors： Ikawa M,Yoshida A

更新日期：1982-08-01 00:00:00

abstract：:Trimethoprim and sulfamethoxazole (Bactrim r) is a widely used antibiotic combination effective against a broad spectrum of microbial organisms. There are reports of neutropenia developing during even brief periods of oral therapy, particularly in individuals with either folate deficiency or increased folate requireme...

journal_title：American journal of hematology

authors： Bjornson BH,McIntyre AP,Harvey JM,Tauber AI

更新日期：1986-09-01 00:00:00

abstract：:During 1971-1988, 194 adults with de novo acute myeloid leukemia (AML) received initial therapy at the University of Minnesota with an anthracycline-based regimen. Seventy-two of the 194 required further chemotherapy and received a second cycle of the same or similar therapy; 63 of these 72 were evaluable. For each ma...

journal_title：American journal of hematology

authors： Hammerschmidt DE,Crea MT

更新日期：1994-11-01 00:00:00

abstract：:The prevention of Rhesus D alloimmunization through Rh immune globulin (RhIg) administration is the major indication for the accurate detection and quantification of fetomaternal hemorrhage (FMH). In the setting of D incompatibility, D-positive fetal cells can sensitize the D-negative mother, resulting in maternal ant...

journal_title：American journal of hematology

authors： Kim YA,Makar RS

更新日期：2012-04-01 00:00:00

abstract：:Chimeric antigen receptors (CARs) can be introduced into T-cells redirecting them to target specific tumor antigens. CAR-modified T cells targeting CD19 have shown remarkable activity against CD19+ malignancies including B cell acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), and non-Hodgkin lymph...

journal_title：American journal of hematology

authors： Frey NV,Porter DL

更新日期：2016-01-01 00:00:00

abstract：:The fat embolism syndrome is an important complication of patients with sickle cell hemoglobinopathies because of severe morbidity and mortality. Our recent experience with three cases that survived with intensive supportive care and prompt use of transfusion stimulates this review. A high index of suspicion, prompt u...

journal_title：American journal of hematology

authors： Dang NC,Johnson C,Eslami-Farsani M,Haywood LJ

更新日期：2005-05-01 00:00:00

abstract：:The soluble form of Fas (sFas) can block apoptosis induced by the Fas ligand in vitro. A recent report demonstrated that mice injected with sFas displayed autoimmune features. Therefore, an elevated serum concentration of sFas may be associated with lymphoproliferation and autoimmune diseases. We measured the serum co...

journal_title：American journal of hematology

authors： Yufu Y,Choi I,Hirase N,Tokoro A,Noguchi Y,Goto T,Uike N,Kozuru M

更新日期：1998-08-01 00:00:00

abstract：:Quantification of sickle hemoglobin (HbS) in patients with sickle cell disease (SCD) undergoing hydroxyurea or chronic transfusion therapy is essential to monitoring the effectiveness of these therapies. The clinical monitoring of %HbS using conventional laboratory methods is limited by high per-test costs and long tu...

journal_title：American journal of hematology

authors： Piety NZ,Yang X,Lezzar D,George A,Shevkoplyas SS

更新日期：2015-06-01 00:00:00

abstract：:Ten previously untreated elderly patients with hypocellular acute leukemia received a low dose of cytosine arabinoside (Ara-C), 10 mg/m2 injected subcutaneously every 12 hours for 14-28 days. Six patients achieved a complete remission (CR) for periods ranging for 6-23 months (median 8.5 months) and the others had a pa...

journal_title：American journal of hematology

authors： Kanamori H,Maruta A,Miyashita H,Harano H,Fukawa H,Matsuzaki M,Motomura S,Mohri H,Kodama F,Okubo T

更新日期：1992-01-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is associated with administration of all plasma containing blood products. We present a 14-year-old adolescent diagnosed with idiopathic thrombocytopenic purpura who developed acute respiratory insufficiency compatible with TRALI within 5 hr following intravenous anti-D. F...

journal_title：American journal of hematology

authors： Berger-Achituv S,Ellis MH,Curtis BR,Wolach B

更新日期：2008-08-01 00:00:00

abstract：:The arachidonic acid metabolites produced by human peripheral blood monocytes were studied to determine which metabolites could have a role in thrombogenesis. Monocytes were found to be free of platelets by scanning electron microscopy and by measurement of 12-HETE. Human peripheral blood monocytes produce thromboxane...

journal_title：American journal of hematology

authors： Jones CM,Hall ER,Hester JP,Wu KK

更新日期：1989-07-01 00:00:00

abstract：:A 64-year-old woman with mild bilateral parotid gland swelling and bilateral lower extremity purpura was admitted for evaluation of xerostomia and pancytopenia. The patient had an increased erythrocyte sedimentation rate, pancytopenia, and positive tests for antibodies to nuclear antigen, SS-A, and SS-B. Impaired cell...

journal_title：American journal of hematology

authors： Seki T,Kiyosawa K,Monno S,Imai Y,Furukawa K,Kumazawa S,Ota M,Saito H,Furuta S,Nakahata T

更新日期：1993-07-01 00:00:00

abstract：:Allogeneic hematopoietic stem cell transplantation (HSCT) represents the only curative option for primary hemophagocytic lymphohistiocytosis (HLH), a rare disease of infants and young children, characterized by recurrent fever, hepatosplenomegaly, and cytopenia. We report a case of successful engraftment and stable fu...

journal_title：American journal of hematology

authors： Cesaro S,Gazzola MV,Marson P,Calore E,Caenazzo L,Destro R,De Silvestro G,Varotto S,Pillon M,Zanesco L,Messina C

更新日期：2003-02-01 00:00:00

abstract：:We report on 3 female patients with immunologic thrombocytopenic purpura (ITP) for whom diagnostic procedures evidenced a chronic Hepatitis C virus (HCV) infection. In 2 cases, a transfusion performed more than 10 years ago represented the probable way of contamination. One patient received a course of steroids, which...

journal_title：American journal of hematology

authors： Bauduer F,Marty F,Larrouy M,Ducout L

更新日期：1998-04-01 00:00:00

abstract：:The -117(G-->A)A gamma hereditary persistence of fetal hemoglobin (Greek HPFH) and beta zero 39-thal mutations are rather frequent in Sardinia so that their interaction is to be expected. Characterization of eight compound heterozygotes for these defects indicated that HPFH was linked to haplotype VII and beta zero 39...

journal_title：American journal of hematology

authors： Pistidda P,Frogheri L,Oggiano L,Guiso L,Manca L,Dore F,Masala B,Gilman JG,Longinotti M

更新日期：1995-08-01 00:00:00

abstract：:Polycythemia vera (PV) is a myeloproliferative disorder characterized by thrombotic and, less often, bleeding complications. Many mechanisms have been advanced to explain the occurrence of these complications, none of them satisfactory. We examined a cohort of 27 patients with PV, secondary erythrocytosis, and essenti...

journal_title：American journal of hematology

authors： Lugassy G,Filin I

更新日期：1999-03-01 00:00:00

abstract：:The binding of anti-human platelet glycoprotein (GP) IIbIIIa monoclonal antibodies to human umbilical vein endothelial cells (HUVE) was studied. Scatchard analysis using 125I-anti-platelet GPIIb-IIIa monoclonal antibody showed that the maximum binding capacity (B max) was 8 X 10(4)/cell and Kd was 40.2 nM. The binding...

journal_title：American journal of hematology

authors： Nakajima T,Koyama T,Kakishita E,Nagai K

更新日期：1987-05-01 00:00:00

abstract：:Peripheral serotonin (5-HT) has been involved in adverse cardiac remodeling and valve fibrosis. The peripheral levels of 5-HT mainly depend on its release from activated platelets and degradation by monoamine oxidase A (MAO-A). The SERAOPI study investigated the relationship between arterial serotoninergic system, deg...

journal_title：American journal of hematology

authors： Rouzaud-Laborde C,Delmas C,Pizzinat N,Tortosa F,Garcia C,Mialet-Perez J,Payrastre B,Sié P,Spreux-Varoquaux O,Sallerin B,Carrié D,Galinier M,Parini A,Lairez O

更新日期：2015-01-01 00:00:00

abstract：:The "platelet function analyzer" (PFA)-100 was first introduced to us in 1995. Since then, the instrument has appeared in over 50 reviews and almost 1000 publications. Recently, the PFA-100 has been "upgraded" to the PFA-200, which has transformed the user interface and electronic management, but retained the fundamen...

journal_title：American journal of hematology

authors： Favaloro EJ

更新日期：2017-04-01 00:00:00

abstract：:Acute myeloid leukemia (AML) with mutated NPM1 is a newly recognized separate entity in the revised 2016 WHO classification, and is associated with a favorable prognosis. While previous studies have evaluated NPM1 in a binary fashion, we recently demonstrated a significant independent negative prognostic effect of hig...

journal_title：American journal of hematology

authors： Patel SS,Pinkus GS,Ritterhouse LL,Segal JP,Dal Cin P,Restrepo T,Harris MH,Stone RM,Hasserjian RP,Weinberg OK

更新日期：2019-08-01 00:00:00

abstract：:Mutation of the VHL tumor suppressor gene is a frequent genetic event in the carcinogenesis of renal-cell carcinoma (RCC). Circulating endothelial progenitor cells (EPCs) have important role in neoangiogenesis, and mobilization of these cells is induced by various growth factors including erythropoietin (EPO). With th...

journal_title：American journal of hematology

authors： Rad FH,Ulusakarya A,Gad S,Sibony M,Juin F,Richard S,Machover D,Uzan G

更新日期：2008-02-01 00:00:00

abstract：:Selective labeling of phagocytes in human blood can be achieved by incubation of unseparated, heparinized blood with 99mTc-sulfur colloid. We have developed a method for quantitation of granulocyte chemotaxis using granulocytes labeled by this technique. The method was found to be more accurate and less tedious to per...

journal_title：American journal of hematology

authors： English D,McPherson TA

更新日期：1977-01-01 00:00:00

abstract：:The increased adhesiveness of sickle erythrocytes (SS RBC) to endothelial cells has been confirmed in a static system utilizing fresh umbilical vein endothelium. Adherence of SS RBC to the endothelium was as great in the presence of calcium-containing buffer as when incubated in plasma. SS RBC suspended in autologous ...

journal_title：American journal of hematology

authors： Antonucci R,Walker R,Herion J,Orringer E

更新日期：1990-05-01 00:00:00

abstract：:Hemostatic changes were evaluated in ten patients with acute lymphoblastic leukemia and lymphoma who received chemotherapy with L-asparaginase, vincristine, and prednisolone for 1 week. Following treatment, prothrombin time and activated partial thromboplastin time were significantly prolonged, while a marked decrease...

journal_title：American journal of hematology

authors： Saito M,Asakura H,Jokaji H,Uotani C,Kumabashiri I,Ito K,Matsuda T

更新日期：1989-09-01 00:00:00

abstract：:In light of the relationship between immune system dysregulation and multiple myeloma (MM) risk, we investigated whether genetic variation in 92 immune function genes among 77 gene regions are associated with MM susceptibility in a population-based case-control study (108 cases and 482 controls) conducted among Caucas...

journal_title：American journal of hematology

authors： Lee KM,Baris D,Zhang Y,Hosgood HD 3rd,Menashe I,Yeager M,Zahm SH,Wang SS,Purdue MP,Chanock S,Zheng T,Rothman N,Lan Q

更新日期：2010-08-01 00:00:00

abstract：:Novel agents in combination with melphalan and prednisone (MP) significantly improved progression-free survival (PFS) and overall survival (OS) in multiple myeloma (MM). Randomized trials comparing MP plus bortezomib (VMP) versus MP plus thalidomide (MPT) are lacking. Nine hundred and fifty-six elderly (>65 years) new...

journal_title：American journal of hematology

authors： Morabito F,Bringhen S,Larocca A,Wijermans P,Victoria Mateos M,Gimsing P,Mazzone C,Gottardi D,Omedè P,Zweegman S,José Lahuerta J,Zambello R,Musto P,Magarotto V,Schaafsma M,Oriol A,Juliusson G,Cerrato C,Catalano L,Gen

更新日期：2014-04-01 00:00:00

abstract：:Recent literature has demonstrated concern over the risk of Pneumocystis jirovecii pneumonia (PJP) when administering rituximab with combination chemotherapy such as in R-CHOP; however, the exact risk and potential need for prophylaxis is unknown. We sought to determine the incidence of PJP infection following R-CHOP ...

journal_title：American journal of hematology

authors： Barreto JN,Ice LL,Thompson CA,Tosh PK,Osmon DR,Dierkhising RA,Plevak MF,Limper AH

更新日期：2016-11-01 00:00:00

abstract：:We report here the haplotypes of 10 MstII-defined SS patients and a S/beta o thalassemia from the Central African Republic, exhibiting 7 different atypical haplotypes that are different from the typical Bantu haplotype that characterize over 93% of the beta s bearing chromosomes in that region of Africa. Of the seven ...

journal_title：American journal of hematology

authors： Srinivas R,Dunda O,Krishnamoorthy R,Fabry ME,Georges A,Labie D,Nagel RL

更新日期：1988-09-01 00:00:00