Exploratory Data Analysis of Adverse Birth Outcomes and Exposure to Oxides of Nitrogen Using Interactive Parallel Coordinates Plot Technique.

abstract：:This study aims to understand through statistical learning the basic biophysical mechanisms behind three-dimensional folding of epigenomes. The 3DEpiLoop algorithm predicts three-dimensional chromatin looping interactions within topologically associating domains (TADs) from one-dimensional epigenomics and transcriptio...

journal_title：Scientific reports

authors： Al Bkhetan Z,Plewczynski D

更新日期：2018-03-26 00:00:00

abstract：:Compression of optical pulses to ultrashort pulse widths using methods of nonlinear optics is a well-established technology of modern laser science. Extending these methods to pulses with high peak powers, which become available due to the rapid progress of laser technologies, is, however, limited by the universal phy...

journal_title：Scientific reports

authors： Voronin AA,Zheltikov AM

更新日期：2017-04-03 00:00:00

abstract：:Oxaliplatin, a chemotherapy medication, causes severe peripheral neuropathy. Although oxaliplatin-induced peripheral neuropathy is a dose-limiting toxicity, a therapeutic strategy against its effects has not been established. We previously reported the involvement of N-methyl-D-aspartate receptors and their intracellu...

journal_title：Scientific reports

authors： Yamamoto S,Ushio S,Egashira N,Kawashiri T,Mitsuyasu S,Higuchi H,Ozawa N,Masuguchi K,Ono Y,Masuda S

更新日期：2017-08-29 00:00:00

abstract：:LiYF4:Eu nanophosphors with a single tetragonal phase are synthesized, and various strategies to enhance the Eu(3+) emission from the nanophosphors are investigated. The optimized Eu(3+) concentration is 35 mol%, and the red emission peaks due to the (5)D0 →(7)FJ (J = 1 and 2) transitions of Eu(3+) ions are further en...

journal_title：Scientific reports

authors： Kim SY,Won YH,Jang HS

更新日期：2015-01-19 00:00:00

abstract：:We propose and demonstrate an on-chip optofluidic device allowing active oscillatory microrheological measurements with sub-μL sample volume, low cost and high flexibility. Thanks to the use of this optofluidic microrheometer it is possible to measure the viscoelastic properties of complex fluids in the frequency rang...

journal_title：Scientific reports

authors： Vitali V,Nava G,Zanchetta G,Bragheri F,Crespi A,Osellame R,Bellini T,Cristiani I,Minzioni P

更新日期：2020-04-02 00:00:00

abstract：:Interferons (IFNs) are key cytokines identified in vertebrates and evolutionary dominance of intronless IFN genes in amniotes is a signature event in IFN evolution. For the first time, we show that the emergence and expansion of intronless IFN genes is evident in amphibians, shown by 24-37 intronless IFN genes in each...

journal_title：Scientific reports

authors： Sang Y,Liu Q,Lee J,Ma W,McVey DS,Blecha F

更新日期：2016-06-30 00:00:00

abstract：:Aquaporin 9 (AQP9), as an aquaglyceroporin, is expressed in many immune cells and plays important role in tumor initiation and progression. However, the relationship between AQP9 and tumor-infiltrating cells, and its prognostic value in cancers still require comprehensive understanding. Herein, we aimed to elucidate t...

journal_title：Scientific reports

authors： Liu X,Xu Q,Li Z,Xiong B

更新日期：2020-11-27 00:00:00

abstract：:Continuous cropping of tomato is increasingly practiced in greenhouse cultivation, leading to several soil-related obstacles. In this study, a type of microbial restoration substrate (MRS) was used to amend soils from the re-cropping of tomato for 8 years under greenhouse-cultivated conditions. Two treatments were est...

journal_title：Scientific reports

authors： Zheng X,Wang Z,Zhu Y,Wang J,Liu B

更新日期：2020-08-13 00:00:00

abstract：:The development of environmentally friendly plant protection products (PPPs), including pesticides, is a challenge nowadays. A commercial herbicide combining terbuthylazine and nicosulfuron as active substances (a.s.) was selected as a model PPP. The suitability of manipulating the ratio between a.s. towards alternati...

journal_title：Scientific reports

authors： Queirós L,Vidal T,Nogueira AJA,Gonçalves FJM,Pereira JL

更新日期：2018-04-03 00:00:00

abstract：:Despite advances in therapy, glioblastoma remains an incurable disease with a dismal prognosis. Recent studies have implicated cancer stem cells within glioblastoma (glioma stem cells, GSCs) as mediators of therapeutic resistance and tumor progression. In this study, we investigated the role of the transforming growth...

journal_title：Scientific reports

authors： Sachdeva R,Wu M,Johnson K,Kim H,Celebre A,Shahzad U,Graham MS,Kessler JA,Chuang JH,Karamchandani J,Bredel M,Verhaak R,Das S

更新日期：2019-10-10 00:00:00

abstract：:Although acute psychosocial stress can impact autobiographical memory retrieval, the nature of this effect is not entirely clear. One reason for this ambiguity is because stress can have opposing effects on the different stages of autobiographical memory retrieval. We addressed this issue by testing how acute stress a...

journal_title：Scientific reports

authors： Sheldon S,Chu S,Nitschke JP,Pruessner JC,Bartz JA

更新日期：2018-06-06 00:00:00

abstract：:Electrical stimulation is a common adjunct used to promote bone healing; its efficacy, however, remains uncertain. We conducted a meta-analysis of randomized sham-controlled trials to establish the efficacy of electrical stimulation for bone healing. We identified all trials randomizing patients to electrical or sham ...

journal_title：Scientific reports

authors： Aleem IS,Aleem I,Evaniew N,Busse JW,Yaszemski M,Agarwal A,Einhorn T,Bhandari M

更新日期：2016-08-19 00:00:00

abstract：:Contact heat evoked potentials (CHEPs) have become an acknowledged research tool in the assessment of the integrity of the nociceptive system and gained importance in the diagnostic work-up of patients with suspected small fiber neuropathy. For the latter, normative values for CHEP amplitude and latency are indispensa...

journal_title：Scientific reports

authors： Rosner J,Hostettler P,Scheuren PS,Sirucek L,Rinert J,Curt A,Kramer JLK,Jutzeler CR,Hubli M

更新日期：2018-07-20 00:00:00

abstract：:To discuss the status of epidemiology of stroke in the Mongolian and Han population aged over 45 years and to understand the treatment and prevention of stroke. Data collected on stroke populations aged over 45 years in the six areas in Inner Mongolia were analyzed by using stratified multi-stage cluster sampling. The...

journal_title：Scientific reports

authors： Zhang C,Lan T,Zhe Y,Hu B,Zhang G,He J,Wang Z,Jiang M,Hu R

更新日期：2017-04-04 00:00:00

abstract：:Extensive research indicates that inter-sexual selection drives the evolution of complex vocal communication in birds, but parallel lines of evidence are almost entirely absent in mammals. This dearth of evidence, particularly among primates, limits our understanding of the link between sociality and vocal complexity....

journal_title：Scientific reports

authors： Gustison ML,Bergman TJ

更新日期：2016-01-21 00:00:00

abstract：:We aimed to report patients' survival after surgical resection of eSCC and to ascertain the clinical, imaging, and pathological factors related to patient prognosis. This retrospective study included 435 patients with eSCC of

journal_title：Scientific reports

authors： Jeong DY,Lee KS,Choi JY,Chung MJ,Min YW,Kim HK,Zo JI,Shim YM,Sun JM

更新日期：2020-03-19 00:00:00

abstract：:Amorphous silicon oxycarbide (SiOC) is of great technological interest. However, its atomic-level structure is not well understood. Using density functional theory calculations, we show that the clustering tendency of C atoms in SiOC is extremely sensitive to hydrogen (H): without H, the C-C interaction is attractive,...

journal_title：Scientific reports

authors： Ding H,Demkowicz MJ

更新日期：2015-08-13 00:00:00

abstract：:The high transparency of graphene, together with its good electrical conductivity and mechanical robustness, enable its use as transparent electrodes in optoelectronic devices such as solar cells. While initial demonstrations of graphene-based organic photovoltaics (OPV) have been promising, realization of scalable te...

journal_title：Scientific reports

authors： Park H,Chang S,Smith M,Gradečak S,Kong J

更新日期：2013-01-01 00:00:00

abstract：:Both heart rate (HR) and brain functioning involve the integrated output of a multitude of regulatory mechanisms, that are not quantified adequately by linear approximations such as means and standard deviations. It was therefore considered whether non-linear measures of HR complexity are more strongly associated with...

journal_title：Scientific reports

authors： Young H,Benton D

更新日期：2015-11-13 00:00:00

abstract：:This study utilized a Förster resonance energy transfer (FRET)-based molecular tension sensor and live cell imaging to evaluate the effect of osteocytes, a mechanosensitive bone cell, on the migratory behavior of tumor cells. Two cell lines derived from MDA-MB-231 breast cancer cells were transfected with the vinculin...

journal_title：Scientific reports

authors： Li F,Chen A,Reeser A,Wang Y,Fan Y,Liu S,Zhao X,Prakash R,Kota D,Li BY,Yokota H,Liu J

更新日期：2019-04-04 00:00:00

abstract：:Vitellogenesis or maternal yolk formation is considered critical to the reproduction of egg-laying animals. In invertebrates, however, most of its regulatory genes are still unknown. Via a combined mapping and whole-genome sequencing strategy, we performed a forward genetic screen to isolate novel regulators of yolk p...

journal_title：Scientific reports

authors： Van Rompay L,Borghgraef C,Beets I,Caers J,Temmerman L

更新日期：2015-11-10 00:00:00

abstract：:This paper describes an origami-inspired self-folding method to form three-dimensional (3D) microstructures of co-cultured cells. After a confluent monolayer of fibroblasts (NIH/3T3 cells) with loaded hepatocytes (HepG2 cells) was cultured onto two-dimensional (2D) microplates, degradation of the alginate sacrificial ...

journal_title：Scientific reports

authors： He Q,Okajima T,Onoe H,Subagyo A,Sueoka K,Kuribayashi-Shigetomi K

更新日期：2018-03-14 00:00:00

abstract：:An increase of nucleolar number and size has made nucleoli essential markers for cytology and tumour development. However, the underlying basis for their structural integrity and abundance remains unclear. Protein phosphatase PPM1D was found to be up-regulated in different carcinomas including breast cancers. Here, we...

journal_title：Scientific reports

authors： Kozakai Y,Kamada R,Furuta J,Kiyota Y,Chuman Y,Sakaguchi K

更新日期：2016-09-13 00:00:00

abstract：:Multiple epidermal growth factor-like-domains 10 (MEGF10), a critical member of the apoptotic engulfment pathway, mediates axon pruning and synapse elimination during brain development. Previous studies indicated that synaptic pruning deficit was associated with autism-related phenotypes. However, the relationship bet...

journal_title：Scientific reports

authors： Wu Z,Qin J,You Y,Ma Y,Jia M,Wang L,Lu T,Yue W,Ruan Y,Zhang D,Li J,Wang L

更新日期：2017-05-23 00:00:00

abstract：:Auxetic mechanical metamaterials are engineered systems that exhibit the unusual macroscopic property of a negative Poisson's ratio due to sub-unit structure rather than chemical composition. Although their unique behaviour makes them superior to conventional materials in many practical applications, they are limited ...

journal_title：Scientific reports

authors： Gatt R,Mizzi L,Azzopardi JI,Azzopardi KM,Attard D,Casha A,Briffa J,Grima JN

更新日期：2015-02-11 00:00:00

abstract：:In the study, we analyzed role of p53 in predicting outcome in visceral metastasis breast cancer (VMBC) patients. 97 consecutive VMBC patients were studied. P53 positivity rate was 29.9%. In the p53-negative group, median disease free survival (DFS), and time from primary breast cancer diagnosis to death (OS1), time f...

journal_title：Scientific reports

authors： Yang P,Du CW,Kwan M,Liang SX,Zhang GJ

更新日期：2013-01-01 00:00:00

abstract：:Validation of imaging contrast agents, such as fluorescently labeled imaging antibodies, has been recognized as a critical challenge in clinical and preclinical studies. As the number of applications for imaging antibodies grows, these materials are increasingly being subjected to careful scrutiny. Antibody fluorescen...

journal_title：Scientific reports

authors： Zhou H,Tourkakis G,Shi D,Kim DM,Zhang H,Du T,Eades WC,Berezin MY

更新日期：2017-02-02 00:00:00

abstract：:Severe sepsis and septic shock are life-threatening conditions, with Gram-negative organisms responsible for most sepsis mortality. Systemic administration of compounds that block the action of lipopolysaccharide (LPS), a constituent of the Gram-negative outer cell membrane, is hampered by their hydrophobicity and cat...

journal_title：Scientific reports

authors： Cho EJ,Doh KO,Park J,Hyun H,Wilson EM,Snyder PW,Tsifansky MD,Yeo Y

更新日期：2016-07-14 00:00:00

abstract：:Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to oncogenesis and chem...

journal_title：Scientific reports

authors： Zhang Y,Zhou SY,Yan HZ,Xu DD,Chen HX,Wang XY,Wang X,Liu YT,Zhang L,Wang S,Zhou PJ,Fu WY,Ruan BB,Ma DL,Wang Y,Liu QY,Ren Z,Liu Z,Zhang R,Wang YF

更新日期：2016-02-05 00:00:00

abstract：:Accurate alignment of an intraocular lens (IOL) is indispensable for achieving accurate postoperative refractive outcomes. Thus, we evaluated decentration and tilt of single- and three-piece IOLs, as well as anterior chamber depth (ACD), at 3 hours, 24 hours, 2 weeks, and 4 weeks after cataract surgery, using swept-so...

journal_title：Scientific reports

authors： Sato T,Shibata S,Yoshida M,Hayashi K

更新日期：2018-07-06 00:00:00