New genetic regulators question relevance of abundant yolk protein production in C. elegans.

abstract：:STIM1 and Orai1 are the main components of a widely conserved Calcium influx pathway known as store-operated calcium entry (SOCE). STIM1 is a calcium sensor, which oligomerizes and activates Orai channels when calcium levels drop inside the endoplasmic reticulum (ER). The series of molecular rearrangements that STIM1 ...

journal_title：Scientific reports

authors： Pacheco J,Dominguez L,Bohórquez-Hernández A,Asanov A,Vaca L

更新日期：2016-07-27 00:00:00

abstract：:Marine blue holes are precious geological heritages with high scientific research values. Their physical and chemical characteristics are unique because of the steep-walled structure and isolated water column which create isolated ecosystems in geographically restricted areas. The Sansha Yongle Blue Hole (SYBH) is the...

journal_title：Scientific reports

authors： Li Q,Lei Y,Morard R,Li T,Wang B

更新日期：2020-06-24 00:00:00

abstract：:Various MRI techniques, including myelin water imaging, T1w/T2w ratio mapping and diffusion-based imaging can be used to characterize tissue microstructure. However, surprisingly few studies have examined the degree to which these MRI measures are related within and between various brain regions. Therefore, whole-brai...

journal_title：Scientific reports

authors： Uddin MN,Figley TD,Solar KG,Shatil AS,Figley CR

更新日期：2019-02-21 00:00:00

abstract：:CaWRKY40 is a positive regulator of pepper (Capsicum annum) response to Ralstonia solanacearum inoculation (RSI), but the underlying mechanism remains largely unknown. Here, we functionally characterize CaCDPK15 in the defense signaling mediated by CaWRKY40. Pathogen-responsive TGA, W, and ERE boxes were identified in...

journal_title：Scientific reports

authors： Shen L,Yang S,Yang T,Liang J,Cheng W,Wen J,Liu Y,Li J,Shi L,Tang Q,Shi W,Hu J,Liu C,Zhang Y,Mou S,Liu Z,Cai H,He L,Guan D,Wu Y,He S

更新日期：2016-03-01 00:00:00

abstract：:γ-Oryzanol (OZ), which has a lot of beneficial effects, is a mixture of ferulic acid esters of triterpene alcohols (i.e., triterpene alcohol type of OZ (TTA-OZ)) and ferulic acid esters of plant sterols (i.e., plant sterol type of OZ (PS-OZ)). Although it has been reported that OZ is found in several kinds of cereal t...

journal_title：Scientific reports

authors： Ito J,Sawada K,Ogura Y,Xinyi F,Rahmania H,Mohri T,Kohyama N,Kwon E,Eitsuka T,Hashimoto H,Kuwahara S,Miyazawa T,Nakagawa K

更新日期：2019-08-29 00:00:00

abstract：:Numerous past studies have investigated neurophysiological correlates of music-syntactic processing. However, only little is known about how prior knowledge about an upcoming syntactically irregular event modulates brain correlates of music-syntactic processing. Two versions of a short chord sequence were presented re...

journal_title：Scientific reports

authors： Guo S,Koelsch S

更新日期：2016-01-19 00:00:00

abstract：:A series of β-NaLuF4 crystals were synthesized via a hydrothermal method. Hexagonal phase microdisks, microprisms, and microtubes were achieved by simply changing the amount of citric acid in the initial reaction solution. Pure red upconversion (UC) luminescence can be observed in β-NaLuF4:Yb(3+), Tm(3+), Er(3+) and L...

journal_title：Scientific reports

authors： Lin H,Xu D,Li A,Teng D,Yang S,Zhang Y

更新日期：2016-06-16 00:00:00

abstract：:V2O5 based materials are attractive cathode alternatives due to the many oxidation state switches of vanadium bringing about a high theoretical specific capacity. However, significant capacity losses are eminent for crystalline V2O5 phases related to the irreversible phase transformations and/or vanadium dissolution s...

journal_title：Scientific reports

authors： Afyon S,Krumeich F,Mensing C,Borgschulte A,Nesper R

更新日期：2014-11-19 00:00:00

abstract：:Bezafibrate (BzF) is eliminated by renal excretion and dosage must be reduced in patients with chronic kidney disease (CKD). There is a concern that BzF causes a further deterioration in renal function in patients with CKD. This study assessed whether BzF discontinuation or dose reduction in CKD patients improves rena...

journal_title：Scientific reports

authors： Zingerman B,Ziv D,Feder Krengel N,Korzets A,Matok I

更新日期：2020-11-13 00:00:00

abstract：:Early admission to the neurosciences intensive care unit (NSICU) is associated with improved patient outcomes. Natural language processing offers new possibilities for mining free text in electronic health record data. We sought to develop a machine learning model using both tabular and free text data to identify pati...

journal_title：Scientific reports

authors： Klang E,Kummer BR,Dangayach NS,Zhong A,Kia MA,Timsina P,Cossentino I,Costa AB,Levin MA,Oermann EK

更新日期：2021-01-14 00:00:00

abstract：:Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive tumors with low survival rates and the leading cause of death in neurofibromatosis type 1 (NF1) patients under 40 years old. Surgical resection is the standard of care for MPNSTs, but is often incomplete and can generate loss of function, necessitating t...

journal_title：Scientific reports

authors： Sweeney EE,Burga RA,Li C,Zhu Y,Fernandes R

更新日期：2016-11-11 00:00:00

abstract：:There is an unmet need for treatments to reduce abdominal aortic aneurysm (AAA) progression. Vascular smooth muscle cell (VSMC) apoptosis precipitates AAA formation, whereas VSMC proliferation repairs the vessel wall. We previously demonstrated that over-expression of EC4-Fc (truncated N-cadherin), or deletion of matr...

journal_title：Scientific reports

authors： Lyon CA,Williams H,Bianco R,Simmonds SJ,Brown BA,Wadey KS,Smith FCT,Johnson JL,George SJ

更新日期：2017-12-11 00:00:00

abstract：:The 2011 Tohoku earthquake drastically changed human activities in some regions of Fukushima Prefecture, Japan. The subsequent tsunami damage and radioactive pollution from the Fukushima Daiichi nuclear power plant resulted in the evacuation of humans, and abandonment of agricultural lands, allowing population expansi...

journal_title：Scientific reports

authors： Anderson D,Toma R,Negishi Y,Okuda K,Ishiniwa H,Hinton TG,Nanba K,Tamate HB,Kaneko S

更新日期：2019-08-08 00:00:00

abstract：:Macrophages play an important role in the inflammatory process that contributes to the development of abdominal aortic aneurysm (AAA). Studies of human and mouse AAA tissue reveal expanded populations of macrophages producing an abundance of pro-inflammatory cytokines, including TNF-α, IL-12p40 and high level of metal...

journal_title：Scientific reports

authors： Yan H,Hu Y,Akk A,Ye K,Bacon J,Pham CTN

更新日期：2019-07-18 00:00:00

abstract：:Immersive virtual reality has become increasingly popular to improve the assessment and treatment of health problems. This rising popularity is likely to be facilitated by the availability of affordable headsets that deliver high quality immersive experiences. As many health problems are more prevalent in older adults...

journal_title：Scientific reports

authors： Huygelier H,Schraepen B,van Ee R,Vanden Abeele V,Gillebert CR

更新日期：2019-03-14 00:00:00

abstract：:A layered nanoreactor (zinc hydroxide gallate/nitrate nanohybrid) has been designed as a nano-vessel to confine the gallate/nitrate reaction inside zinc hydroxide layers for production of metal/nitrogen-doped carbon catalysts. Metals (Fe2+, Co2+ and Ni2+) doped and bare zinc hydroxide nitrates (ZHN) were synthesized a...

journal_title：Scientific reports

authors： Yeganeh Ghotbi M,Javanmard A,Soleimani H

更新日期：2018-02-21 00:00:00

abstract：:Multiple sources of sensory information are combined to develop hand posture percepts in the intact system, but the combination of multiple artificial somatosensory percepts by human prosthesis users has not been studied. Here, we report on a case study in which a person with transradial amputation identified prosthet...

journal_title：Scientific reports

authors： Segil JL,Cuberovic I,Graczyk EL,Weir RFF,Tyler D

更新日期：2020-04-20 00:00:00

abstract：:We propose two generalized Haldane models on laser-coupling optical lattices. Laser-assisted nearest neighbour tunnelings generate artificial staggered magnetic flux, facilitating the realization of topological nontrivial band structures. As generalizations of Haldane model, these models support topological insulator ...

journal_title：Scientific reports

authors： Liu W,Lin Z,Wang ZD,Chen Y

更新日期：2018-08-27 00:00:00

abstract：:Alcohol consumption has been shown to cause dysbiosis, but the mechanism involved in it is unknown. Recurrent colitis is known to induce expression of α-defensins in the colon, but the effect of alcohol consumption on it is not known. We investigated the effect of ethanol on α-defensin expression in the small intestin...

journal_title：Scientific reports

authors： Shukla PK,Meena AS,Rao V,Rao RG,Balazs L,Rao R

更新日期：2018-11-02 00:00:00

abstract：:The Southern Ocean has taken up more than 40% of the total anthropogenic carbon (Cant) stored in the oceans since the preindustrial era, mainly in subantarctic mode and intermediate waters (SAMW-AAIW). However, the physical mechanisms responsible for the transfer of Cant into the ocean interior remain poorly understoo...

journal_title：Scientific reports

authors： Langlais CE,Lenton A,Matear R,Monselesan D,Legresy B,Cougnon E,Rintoul S

更新日期：2017-12-06 00:00:00

abstract：:Although the effects of osteoporosis on the skeleton are well studied, site-specific and long-term studies on the mandible are still lacking. This study investigated the time-course changes of the bone microarchitecture in the mandibular condyle in comparison to the corresponding changes in the alveolar bone, body of ...

journal_title：Scientific reports

authors： Lee C,Lee JH,Han SS,Kim YH,Choi YJ,Jeon KJ,Jung HI

更新日期：2019-10-02 00:00:00

abstract：:Psoriasis is a chronic, relapsing inflammatory skin disease. The pathogenesis of psoriasis is complex and has not been fully understood. C10orf99 was a recently identified human antimicrobial peptide whose mRNA expression is elevated in psoriatic human skin samples. In this study, we investigated the functional roles ...

journal_title：Scientific reports

authors： Chen C,Wu N,Duan Q,Yang H,Wang X,Yang P,Zhang M,Liu J,Liu Z,Shao Y,Zheng Y

更新日期：2018-06-05 00:00:00

abstract：:Microglia are the resident phagocytic cells with various functions in the central nervous system, and the morphologies of microglia imply the different stages and functions. In optical nerve transection (ONT) model in the retina, the retrograde degeneration of retinal ganglion cells (RGCs) induces microglial activatio...

journal_title：Scientific reports

authors： Yuan TF,Liang YX,Peng B,Lin B,So KF

更新日期：2015-06-02 00:00:00

abstract：:It is a common belief that reptile eggs should not be turned after oviposition once the embryo has attached itself to the inner membrane of the shell as it might kill developing embryos. Here, we used 338 eggs from 32 clutches of the water snake Natrix maura to (1) thoroughly describe natural clutch arrangement, (2) e...

journal_title：Scientific reports

authors： Aubret F,Blanvillain G,Kok PJ

更新日期：2015-08-21 00:00:00

abstract：:Ubiquinol-cytochrome c reductase hinge protein (UQCRH) is the hinge protein for the multi-subunit complex III of the mitochondrial electron transport chain and is involved in the electron transfer reaction between cytochrome c1 and c. Recent genome-wide transcriptomic and epigenomic profiling of clear cell renal cell ...

journal_title：Scientific reports

authors： Luo Y,Medina Bengtsson L,Wang X,Huang T,Liu G,Murphy S,Wang C,Koren J 3rd,Schafer Z,Lu X

更新日期：2020-09-14 00:00:00

abstract：:Herbs may contain pesticide residues which are an important discriminator of food security and food quality. The challenge of the research was to assess the fate of the herbicide clethodim (CLE) and the insecticide spirotetramat (SPI) applied in herbs (BBCH 11-21) during herb growth and processing under controlled gre...

journal_title：Scientific reports

authors： Jankowska M,Kaczyński P,Łozowicka B

更新日期：2020-01-28 00:00:00

abstract：:Jasmonates (JAs) are plant-specific key signaling molecules that respond to various stimuli and are involved in the synthesis of secondary metabolites. However, little is known about the JA signal pathway, especially in economically significant medicinal plants. To determine the functions of novel genes that participa...

journal_title：Scientific reports

authors： Ge Q,Zhang Y,Hua WP,Wu YC,Jin XX,Song SH,Wang ZZ

更新日期：2015-09-21 00:00:00

abstract：:Fibrosis with excessive amounts of type I collagen is a hallmark of many solid tumours, and fibrosis is a promising target in cancer therapy, but tools for its non-invasive quantification are missing. Here we used magnetic resonance imaging with a gadolinium-based probe targeted to type I collagen (EP-3533) to image a...

journal_title：Scientific reports

authors： Polasek M,Yang Y,Schühle DT,Yaseen MA,Kim YR,Sung YS,Guimaraes AR,Caravan P

更新日期：2017-08-14 00:00:00

abstract：:In a 250-kyr transient simulation of the Community Earth System Model (CESM), we identified a precessional forced seesaw of the summer middle-upper tropospheric eddy temperature between Asia and the North Pacific as the paleo-APO (Asian-Pacific oscillation). The paleo-APO variability is out of phase with the precessio...

journal_title：Scientific reports

authors： Wang Y,Jian Z,Zhao P,Xiao D,Chen J

更新日期：2016-07-06 00:00:00

abstract：:Chloromethane (CH3Cl) is a toxic gas mainly produced naturally, in particular by plants, and its emissions contribute to ozone destruction in the stratosphere. Conversely, CH3Cl can be degraded and used as the sole carbon and energy source by specialised methylotrophic bacteria, isolated from a variety of environments...

journal_title：Scientific reports

authors： Farhan Ul Haque M,Besaury L,Nadalig T,Bringel F,Mutterer J,Schaller H,Vuilleumier S

更新日期：2017-12-14 00:00:00