Three-dimensional Epigenome Statistical Model: Genome-wide Chromatin Looping Prediction.

abstract：:Although redox reactions are recognized to fractionate iron (Fe) isotopes, the dominant mechanisms controlling the Fe isotope fractionation and notably the role of organic matter (OM) are still debated. Here, we demonstrate how binding to organic ligands governs Fe isotope fractionation beyond that arising from redox ...

journal_title：Scientific reports

authors： Lotfi-Kalahroodi E,Pierson-Wickmann AC,Rouxel O,Marsac R,Bouhnik-Le Coz M,Hanna K,Davranche M

更新日期：2021-01-21 00:00:00

abstract：:Immunoaffinity enrichment of proteotypic peptides, coupled with selected reaction monitoring, enables indirect protein quantification. However the lack of suitable antibodies limits its widespread application. We developed a method in which multi-specific antibodies are used to enrich groups of peptides, thus facilita...

journal_title：Scientific reports

authors： Weiß F,Schnabel A,Planatscher H,van den Berg BH,Serschnitzki B,Nuessler AK,Thasler WE,Weiss TS,Reuss M,Stoll D,Templin MF,Joos TO,Marcus K,Poetz O

更新日期：2015-03-04 00:00:00

abstract：:Early antiretroviral therapy (ART) initiation is a recommended public health approach for the prevention of HIV-1 transmission. In this cohort study, we included 13132 serodiscordant couples. ART was initiated for patients with CD4+ T cell counts less than 200 cells/uL, 350 cells/uL, and 500 cells/uL respectively. Thi...

journal_title：Scientific reports

authors： Liu P,Tang Z,Lan G,Zhu Q,Chen H,You Y,Yang X,Liang S,Chen Y,Xing H,Liao L,Feng Y,Shen Z,Ruan Y,Shao Y

更新日期：2018-02-21 00:00:00

abstract：:Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomic analysis. We foun...

journal_title：Scientific reports

authors： Kim J,Kim I,Han SK,Bowie JU,Kim S

更新日期：2012-01-01 00:00:00

abstract：:A fundamental assumption in bioacoustics is that large animals tend to produce vocalizations with lower frequencies than small animals. This inverse relationship between body size and vocalization frequencies is widely considered to be foundational in animal communication, with prominent theories arguing that it playe...

journal_title：Scientific reports

authors： Bowling DL,Garcia M,Dunn JC,Ruprecht R,Stewart A,Frommolt KH,Fitch WT

更新日期：2017-01-24 00:00:00

abstract：:Grazing and burrowing organisms usually homogenise microalgal mats that form on benthic sediments of many aquatic ecosystems. In the absence of this disruption, microalgal mats can accrete laminated deposits (stromatolites). Stromatolites are rare in modern coastal ecosystems, but persist at locations where metazoans ...

journal_title：Scientific reports

authors： Rishworth GM,Perissinotto R,Bird MS,Strydom NA,Peer N,Miranda NA,Raw JL

更新日期：2017-02-16 00:00:00

abstract：:Laminotomy and transforaminal lumbar interbody fusion (TLIF) is usually used to treat unstable spinal stenosis. Minimally invasive surgery (MIS) can cause less muscle injury than conventional open surgery (COS). The purpose of this study was to compare the degree of postoperative fatty degeneration in the paraspinal m...

journal_title：Scientific reports

authors： Fu CJ,Chen WC,Lu ML,Cheng CH,Niu CC

更新日期：2020-09-03 00:00:00

abstract：:Ceramide is one of the most important intercellular components responsible for the barrier and moisture retention functions of the skin. Because of the risks involved with using products of animal origin and the low productivity of plants, the availability of ceramides is currently limited. In this study, we successfu...

journal_title：Scientific reports

authors： Murakami S,Shimamoto T,Nagano H,Tsuruno M,Okuhara H,Hatanaka H,Tojo H,Kodama Y,Funato K

更新日期：2015-11-17 00:00:00

abstract：:Psychiatric disorders have been widely reported to be associated with systemic inflammation upregulation and adiposity. However, there are no data that link adipose tissue inflammation to these mental disorders. The analysis of adipokines and inflammation-related markers in adipose tissue could help to elucidate the p...

journal_title：Scientific reports

authors： Coín-Aragüez L,Pavón FJ,Contreras A,Gentile AM,Lhamyani S,De Diego-Otero Y,Casado Y,Oliva Olivera W,Olveira G,Tinahones FJ,Pérez Costillas L,El Bekay R

更新日期：2018-11-30 00:00:00

abstract：:The neurology of male sexuality has been poorly studied owing to difficulties in studying brain circuitry in humans. Dopamine (DA) is essential for both physiological and behavioural responses, including the regulation of sexuality. Previous studies have revealed that alterations in DA synthesis in dopaminergic neuron...

journal_title：Scientific reports

authors： Chen SL,Chen YH,Wang CC,Yu YW,Tsai YC,Hsu HW,Wu CL,Wang PY,Chen LC,Lan TH,Fu TF

更新日期：2017-03-15 00:00:00

abstract：:L-asparaginase is a chemotherapy drug used to treat acute lymphoblastic leukemia (ALL). The main prerequisite for clinical efficacy of L-asparaginases is micromolar KM for asparagine to allow for complete depletion of this amino acid in the blood. Since currently approved L-asparaginases are of bacterial origin, immun...

journal_title：Scientific reports

authors： Rigouin C,Nguyen HA,Schalk AM,Lavie A

更新日期：2017-08-31 00:00:00

abstract：:Recent discoveries have highlighted the novel metabolic functions of adipose tissue in enhancing hypermetabolism after trauma. As the exact function and expression profiles of serum lipids and free fatty acids (FFA) are essentially unknown, we determined the lipidomic expression profile after burn in correlation to cl...

journal_title：Scientific reports

authors： Qi P,Abdullahi A,Stanojcic M,Patsouris D,Jeschke MG

更新日期：2016-12-16 00:00:00

abstract：:Arsenic contamination of groundwater is a serious concern worldwide. The research gaps in removing arsenic are selectivity, regeneration and effective removal rate at neutral pH levels. In this study, we discussed the reasons of the high arsenic adsorption from groundwater of our previously developed adsorbent, a cati...

journal_title：Scientific reports

authors： Safi SR,Senmoto K,Gotoh T,Iizawa T,Nakai S

更新日期：2019-08-15 00:00:00

abstract：:Bezafibrate (BzF) is eliminated by renal excretion and dosage must be reduced in patients with chronic kidney disease (CKD). There is a concern that BzF causes a further deterioration in renal function in patients with CKD. This study assessed whether BzF discontinuation or dose reduction in CKD patients improves rena...

journal_title：Scientific reports

authors： Zingerman B,Ziv D,Feder Krengel N,Korzets A,Matok I

更新日期：2020-11-13 00:00:00

abstract：:We propose an ultrathin metallic structure to produce frequency-selective spoof surface plasmon polaritons (SPPs) in the microwave and terahertz frequencies. Designed on a thin dielectric substrate, the ultrathin metallic structure is composed of two oppositely oriented single-side corrugated strips, which are coupled...

journal_title：Scientific reports

authors： Yin JY,Ren J,Zhang HC,Pan BC,Cui TJ

更新日期：2015-02-02 00:00:00

abstract：:The spreading of invasive species in new continents can vary from slow and limited diffusion to fast colonisations over vast new areas. We studied the sacred ibis Threskiornis aethiopicus along a 31-year period, from 1989 to 2019, with particular attention to the first area of release in NW Italy. We collected data on...

journal_title：Scientific reports

authors： Cucco M,Alessandria G,Bissacco M,Carpegna F,Fasola M,Gagliardi A,Gola L,Volponi S,Pellegrino I

更新日期：2021-01-08 00:00:00

abstract：:Albacore tuna (Thunnus alalunga) is an important target of tuna fisheries in the Atlantic and Indian Oceans. The commercial catch of albacore is the highest globally among all temperate tuna species, contributing around 6% in weight to global tuna catches over the last decade. The accurate assessment and management of...

journal_title：Scientific reports

authors： Nikolic N,Montes I,Lalire M,Puech A,Bodin N,Arnaud-Haond S,Kerwath S,Corse E,Gaspar P,Hollanda S,Bourjea J,West W,Bonhommeau S

更新日期：2020-09-24 00:00:00

abstract：:The gene PFKFB3 encodes for inducible 6-phosphofructo-2-kinase, a glycolysis-regulatory enzyme that protects against diet-induced intestine inflammation. However, it is unclear how nutrient overload regulates PFKFB3 expression and inflammatory responses in intestinal epithelial cells (IECs). In the present study, prim...

journal_title：Scientific reports

authors： Botchlett R,Li H,Guo X,Qi T,Zhao J,Zheng J,Woo SL,Pei Y,Liu M,Hu X,Chen G,Guo T,Yang S,Li Q,Xiao X,Huo Y,Wu C

更新日期：2016-07-08 00:00:00

abstract：:Post-infectious bronchiolitis obliterans (BO) could be diagnosed via spirometry and chest computed tomography (CT); however, these tests are limited in infants. We aimed to evaluate the utility of lung clearance index (LCI) and air-trapping lung volume from chest CT in infants. This prospective study included 20 infan...

journal_title：Scientific reports

authors： Kim YH,Shin HJ,Sol IS,Kim SY,Kim JD,Yoon H,Kim KW,Kim MJ,Lee MJ,Sohn MH

更新日期：2017-11-09 00:00:00

abstract：:Coral reefs all over the Indo-Pacific suffer from substantial damage caused by the crown-of-thorns seastar Acanthaster planci, a voracious predator that moves on and between reefs to seek out its coral prey. Chemoreception is thought to guide A. planci. As vision was recently introduced as another sense involved in se...

journal_title：Scientific reports

authors： Sigl R,Steibl S,Laforsch C

更新日期：2016-08-01 00:00:00

abstract：:Site-specific genome modification (SSM) is an important tool for mosquito functional genomics and comparative gene expression studies, which contribute to a better understanding of mosquito biology and are thus a key to finding new strategies to eliminate vector-borne diseases. Moreover, it allows for the creation of ...

journal_title：Scientific reports

authors： Häcker I,Harrell Ii RA,Eichner G,Pilitt KL,O'Brochta DA,Handler AM,Schetelig MF

更新日期：2017-03-07 00:00:00

abstract：:Transient gene expression approaches are valuable tools for rapid introduction of genes of interest and characterization of their functions in plants. Although agroinfiltration is the most effectively and routinely used method for transient expression of multiple genes in various plant species, this approach has been ...

journal_title：Scientific reports

authors： Seo JK,Choi HS,Kim KH

更新日期：2016-02-29 00:00:00

abstract：:Formamidinium lead iodide (CH(NH2)2PbI3, FAPI) thin films have been deposited on glass substrates at 150 °C using ambient pressure aerosol assisted chemical vapour deposition (AACVD). The films have been analysed by a range of techniques including powder X-ray diffraction (pXRD), scanning electron microscopy (SEM), en...

journal_title：Scientific reports

authors： Alam F,Lewis DJ

更新日期：2020-12-17 00:00:00

abstract：:Investigation of quantum spin Hall states in 1T' phase of the monolayer transition metal dichalcogenides has recently attracted the attention for its potential in nanoelectronic applications. While most of the theoretical findings in this regard deal with infinitely periodic crystal structures, here we employ density ...

journal_title：Scientific reports

authors： Das B,Sen D,Mahapatra S

更新日期：2020-04-21 00:00:00

abstract：:The triatomine Rhodnius prolixus, a vector of the etiological agent of Chagas disease, has long been used as model to understand important aspects of insect physiology. Despite this history, the impact of the nutritional state on regulatory pathways associated with reproductive performance in triatomines has never bee...

journal_title：Scientific reports

authors： Leyria J,Orchard I,Lange AB

更新日期：2020-07-10 00:00:00

abstract：:The secreted frizzled-related protein 5 gene (SFRP5) that antagonize the Wnt/β-catenin signaling is frequently inactivated by promoter methylation and oncogenic activation of the Wnt signaling pathway is common in many cancers. The curcumin-rich Curcuma longa has been reported to potent anti-cancer property involved i...

journal_title：Scientific reports

authors： Yen HY,Tsao CW,Lin YW,Kuo CC,Tsao CH,Liu CY

更新日期：2019-11-21 00:00:00

abstract：:Surfactant solutions typically feature tunable nanoscale, internal structures. Although rarely utilized, they can be a powerful platform for probing thermal transport in nanoscale domains and across interfaces with nanometer-size radius. Here, we examine the structure and thermal transport in solution of AOT (Dioctyl ...

journal_title：Scientific reports

authors： Cao F,Liu Y,Xu J,He Y,Hammouda B,Qiao R,Yang B

更新日期：2015-11-04 00:00:00

abstract：:Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery. As human pluripotent stem cell-derived cardiomyocytes remain functionally fetal-type, close monitoring of electrophysiological maturation is critical for their furthe...

journal_title：Scientific reports

authors： Zhu H,Scharnhorst KS,Stieg AZ,Gimzewski JK,Minami I,Nakatsuji N,Nakano H,Nakano A

更新日期：2017-03-07 00:00:00

abstract：:One of the greatest enigmas of modern biology is how the geometry of muscular and skeletal structures are created and how their development is controlled during growth and regeneration. Scaling and shaping of vertebrate muscles and skeletal elements has always been enigmatic and required an advanced technical level in...

journal_title：Scientific reports

authors： Tesařová M,Mancini L,Simon A,Adameyko I,Kaucká M,Elewa A,Lanzafame G,Zhang Y,Kalasová D,Szarowská B,Zikmund T,Novotná M,Kaiser J

更新日期：2018-09-20 00:00:00

abstract：:For the past 30 years, oocytes from Xenopus laevis have been extensively used to express and characterise ion channels in an easily controlled environment. Here we report the first use of oocytes from the closely related species Xenopus borealis as an alternative expression system for neuronal ion channels. Using the ...

journal_title：Scientific reports

authors： Cristofori-Armstrong B,Soh MS,Talwar S,Brown DL,Griffin JD,Dekan Z,Stow JL,King GF,Lynch JW,Rash LD

更新日期：2015-10-06 00:00:00