Abstract:
:We aimed to report patients' survival after surgical resection of eSCC and to ascertain the clinical, imaging, and pathological factors related to patient prognosis. This retrospective study included 435 patients with eSCC of journal_name journal_title authors doi subject pub_date pages issue issn pii journal_volume pub_type
abstract::Although the cognitive impairment in Alzheimer's disease (AD) is believed to be caused by amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs), several postmortem studies have reported cognitive normal subjects with AD brain pathology. As the mechanism underlying these discrepancies has not been clarified, we foc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19442-7
更新日期:2018-01-26 00:00:00
abstract::Annual reduction rate of corneal endothelial cell density (ECD) varies among etiologies, however, the cause of chronic endothelial cell loss is still unknown. We recently reported the elevation of inflammatory cytokines in the aqueous humor (AqH) in eyes with bullous keratopathy and low ECD. To evaluate the associatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14131-3
更新日期:2017-10-19 00:00:00
abstract::In this work, lamellar MnFe2O4 was successfully planted on a wood surface through the association of hydrogen bonds via the one-pot hydrothermal method. Simultaneously, the fluoroalkylsilane (FAS-17) on the surface of the MnFe2O4 layer formed long-chain or network macromolecules through a poly-condensation process and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35549
更新日期:2016-10-17 00:00:00
abstract::This study aims to evaluate the radiation dosimetry of a new technetium-99m‒labelled small-molecule inhibitor of prostate-specific membrane antigen (HYNIC-Glu-Urea-A, 99mTc-HYNIC-PSMA) and its feasibility as a tumor-imaging agent in prostate cancer (PCa) patients. A total of 15 PCa patients were enrolled in this study...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61129-5
更新日期:2020-03-06 00:00:00
abstract::Neutrophils are the first immune cells to kill invading microbes at sites of infection using a variety of processes, including the release of proteases, phagocytosis and the production of neutrophil extracellular traps (NETs). NET formation, or NETosis, is a specific and highly efficient process, which is induced by a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53058-9
更新日期:2019-11-12 00:00:00
abstract::To determine whether any brain MR abnormalities, including enlarged perivascular spaces (EPVS), were associated with disease activity in systemic lupus erythematosus (SLE) as an inflammatory activity. One hundred and thirty SLE patients with normal MR findings were assessed. With regard to MRI abnormalities, patients ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12966-4
更新日期:2017-10-03 00:00:00
abstract::Baited remote underwater video cameras were deployed in the Eastern Canadian Arctic, for the purpose of estimating local densities of the long-lived Greenland shark within five deep-water, data-poor regions of interest for fisheries development and marine conservation in Nunavut, Canada. A total of 31 camera deploymen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-19115-x
更新日期:2018-01-17 00:00:00
abstract::Gallic acid is a trihydroxybenzoic acid found in tea leaves and some plants. Here, we report the effect of gallic acid on cardiac dysfunction and fibrosis in a mouse model of pressure overload-induced heart failure and in primary rat cardiac fibroblasts, and compare the effects of gallic acid with those of drugs used ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27599-4
更新日期:2018-06-18 00:00:00
abstract::Steep-slope transistors allow to scale down the supply voltage and the energy per computed bit of information as compared to conventional field-effect transistors (FETs), due to their sub-60 mV/decade subthreshold swing at room temperature. Currently pursued approaches to achieve such a subthermionic subthreshold swin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00359-6
更新日期:2017-03-23 00:00:00
abstract::In the modern era, diathermic oils have been gotten the great attention from researchers due to its notable and momentous applications in engineering, mechanics and in the industrial field. The aim of this paper is to model the problem to augment the heat transfer rate of diathermic oils, specifically, Engine-oil (EO)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33547-z
更新日期:2018-10-16 00:00:00
abstract::Many experimental techniques rely on specific recognition and stringent binding of proteins by antibodies. This can readily be achieved by introducing an epitope tag. We employed an approach that uses a relative lack of evolutionary conservation to inform epitope tag site selection, followed by integration of the tag-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36986
更新日期:2016-11-28 00:00:00
abstract::The metal-air battery is a form of renewable energy generation technology that produces energy electrochemically and can address energy concerns in the near future. However, state-of-the-art Pt electrocatalysts often suffer from agglomeration or detachment from carbon supports under prolonged operation, eventually lim...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49194-x
更新日期:2019-09-03 00:00:00
abstract::Beta-glucans are a heterologous group of fibrous glucose polymers that are a major constituent of cell walls in Ascomycetes and Basidiomycetes fungi. Synthesis of β (1,3)- and (1,6)-glucans is coordinated with fungal cell growth and development, thus, is under tight genetic regulation. Here, we report that β-glucan sy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10199
更新日期:2015-05-11 00:00:00
abstract::Satellite aerosol optical depth (AOD) is widely used to estimate particulate matter with aerodynamic diameter ≤2.5 µm (PM2.5) mass concentrations. Polar orbiting satellite retrieval 1-2 times each day is frequently affected by cloud, snow cover or misclassification of heavy pollution. Novel methods are therefore requi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28535-2
更新日期:2018-07-05 00:00:00
abstract::The reliable identification of diffuse large B-cell lymphoma (DLBCL)-specific targets owns huge implications for its diagnosis and treatment. Long non-coding RNAs (lncRNAs) are implicated in DLBCL pathogenesis; however, circulating DLBCL-related lncRNAs are barely investigated. We investigated plasma lncRNAs; HOTAIR, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81715-5
更新日期:2021-01-22 00:00:00
abstract::Breast cancer is the most frequently diagnosed malignancy among women, and triple-negative breast cancer (TNBC) is a highly aggressive subtype. Increasing evidence has shown that lncRNAs are involved in tumor growth, cell-cycle, and apoptosis through interactions with miRNAs or mRNAs. However, there is still limited d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51626-7
更新日期:2019-10-22 00:00:00
abstract::Mitochondrial dysfunction and significant changes in metabolic pathways accompany cancer development and are responsible for maintaining the tumor microenvironment. Normal mitochondria can trigger intrinsic apoptosis by releasing cytochrome c into the cytosol. The survival of malignant cells highly depends on the supp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71118-3
更新日期:2020-08-25 00:00:00
abstract::Magnetite (Fe3O4) is an iron ore mineral that is globally mined especially for steel production. It is denser (5.15 g/cm3) than Earth's crust (~2.7 g/cm3) and is expected to accumulate at the bottom of melt-rich magma reservoirs. However, recent studies revealed heterogeneous fluid bubble nucleation on oxide minerals ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40376-1
更新日期:2019-03-07 00:00:00
abstract::This cross-sectional study aimed to investigate the prevalence and risk factors of chronic kidney disease (CKD) among 1,096 primary care type 2 diabetes (T2DM) patients in northern Thailand between October 2016 and September 2017. CKD was defined as estimated glomerular rate filtration values of <60 mL/min/1.73 m2. Pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63443-4
更新日期:2020-04-10 00:00:00
abstract::The exact mechanism of endometriosis is unknown. The recommendation system (RS) based on item similarities of machine learning has never been applied to the relationship between diseases. The study aim was to identify diseases associated with endometriosis by applying RS based on item similarities to insurance data in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41973-w
更新日期:2019-04-01 00:00:00
abstract::Therapies targeting somatic bystander genetic events represent a new avenue for cancer treatment. We recently identified a subset of colorectal cancer (CRC) patients who are heterozygous for a wild-type and a low activity allele (NAT2*6) but lack the wild-type allele in their tumors due to loss of heterozygosity (LOH)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80288-z
更新日期:2020-12-31 00:00:00
abstract::Bezafibrate (BzF) is eliminated by renal excretion and dosage must be reduced in patients with chronic kidney disease (CKD). There is a concern that BzF causes a further deterioration in renal function in patients with CKD. This study assessed whether BzF discontinuation or dose reduction in CKD patients improves rena...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76861-1
更新日期:2020-11-13 00:00:00
abstract::One procedure widely used to detect the velocity of a moving object is by using the Doppler effect. This is the perceived change in frequency of a wave caused by the relative motion between the emitter and the detector, or between the detector and a reflecting target. The relative movement, in turn, generates a time-v...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02815
更新日期:2013-10-02 00:00:00
abstract::With millions of new dental and orthopedic implants inserted annually, periprosthetic osteolysis becomes a major concern. In dentistry, peri-implantitis management includes cleaning using ultrasonic scaling. We examined whether ultrasonic scaling releases titanium particles and induces inflammation and osteolysis. Tit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39612
更新日期:2017-01-06 00:00:00
abstract::The accumulation of fat, especially in visceral sites, is a significant risk factor for several chronic diseases with altered cardiometabolic homeostasis. We studied how intensive long-term weight loss and subsequent weight regain affect physiological changes, by longitudinally interrogating the lipid metabolism and w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40107-6
更新日期:2019-03-05 00:00:00
abstract::Cellular interactions can be modeled as complex dynamical systems represented by weighted graphs. The functionality of such networks, including measures of robustness, reliability, performance, and efficiency, are intrinsically tied to the topology and geometry of the underlying graph. Utilizing recently proposed geom...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12323
更新日期:2015-07-14 00:00:00
abstract::DNA focused panel sequencing has been rapidly adopted to assess therapeutic targets in advanced/refractory cancer. Integrated Genomic Profiling (IGP) utilising DNA/RNA with tumour/normal comparisons in a Clinical Laboratory Improvement Amendments (CLIA) compliant setting enables a single assay to provide: therapeutic ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-016-0021-4
更新日期:2016-12-23 00:00:00
abstract::Sarcopenia is an aging condition involving low muscle mass and function. Fetuin-A (FetA) appears to be a factor for body composition remodeling. We hypothesized that age increases FetA levels and deteriorates the myocardial function by affecting diastolic function, especially in people with sarcopenia. We enrolled 541...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12078
更新日期:2015-07-10 00:00:00
abstract::Pediatric obstructive sleep-disordered breathing is associated with growth retardation, but also with obesity that has a tendency to persist following treatment. We investigated the effect of upper airways obstruction (AO) and of obstruction removal (OR) in juvenile rats on gut-derived ghrelin and related hypothalamic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02843-5
更新日期:2017-06-02 00:00:00
abstract::Optical polarizing devices exploiting graphene embedded in waveguides have been demonstrated in the literature recently and both the TE- and TM-pass behaviors were reported. The determination of the passing polarization is usually attributed to graphene's Fermi level (and, therefore, doping level), with, however, no d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16949
更新日期:2015-11-19 00:00:00