Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Rueckert E,Čamernik J,Peters J,Babič Jdoi
10.1038/s41598-020-63129-xsubject
Has Abstractpub_date
2020-04-16 00:00:00pages
6694issue
1issn
2045-2322pii
10.1038/s41598-020-63129-xjournal_volume
10pub_type
已发布勘误abstract::A fundamental question in biology is how cell populations evolve into different subtypes based on homogeneous processes at the single cell level. Here we show that population bimodality can emerge even when biological processes are homogenous at the cell level and the environment is kept constant. Our model is based o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45882-w
更新日期:2019-06-28 00:00:00
abstract::This corrects the article DOI: 10.1038/srep25577. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/srep46944
更新日期:2018-02-16 00:00:00
abstract::This study aimed to determine the characteristics of CT changes in patients with severe coronavirus disease 2019 (COVID-19) based on prognosis. Serial CT scans in 47 patients with severe COVID-19 were reviewed. The patterns, distribution and CT score of lung abnormalities were assessed. Scans were classified according...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78965-0
更新日期:2020-12-14 00:00:00
abstract::The potential of Massively Parallel Sequencing (MPS) technology to vastly expand the capabilities of human identification led to the emergence of different MPS platforms that use forensically relevant genetic markers. Two of the MPS platforms that are currently available are the MiSeq® FGx™ Forensic Genomics System (I...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00510-3
更新日期:2017-03-24 00:00:00
abstract::Bleaching, the loss of algal symbionts, occurs in marine photosymbiotic organisms at water temperatures minimally exceeding average summer SST (sea surface temperatures). Pre-adaptation allows organisms to persist under warmer conditions, providing the tolerance can be carried to new habitats. Here we provide evidence...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30930
更新日期:2016-08-09 00:00:00
abstract::This study used resting-state functional MRI (r-fMRI) to evaluate intrinsic brain activity in drug-naive patients with essential tremor (ET) with and without head tremor. We enrolled 20 patients with ET with hand and head tremor (h-ET), 27 patients with ET without head tremor (a-ET), and 27 healthy controls (HCs). All...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28778-z
更新日期:2018-07-12 00:00:00
abstract::Clinical observations suggest neuronal control of bone remodeling. Sensory nerve fibers innervating bone, bone marrow and periosteum signal via neurotransmitters including substance P (SP). In previous studies we observed impaired biomechanical and structural bone parameters in tachykinin (Tac) 1-deficient mice lackin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27432-y
更新日期:2018-06-15 00:00:00
abstract::Opioids are effective analgesics for the management of moderate to severe cancer pain. Here we show that κ opioid receptor (KOR) agonists act as anti-angiogenic factors in tumors. Treatment with KOR agonists, U50,488H and TRK820, significantly inhibited human umbilical vein endothelial cell (HUVEC) migration and tube ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03213
更新日期:2013-11-14 00:00:00
abstract::Atherosclerotic arteries exhibit characteristic constrictions and substantial deviations from cylindrical shape. Therefore, determining the artery's cross-section along the centerline is challenging, although high-resolution isotropic three-dimensional data are available. Herein, we apply high-resolution computed tomo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50711-1
更新日期:2019-10-04 00:00:00
abstract::We design a novel long-range hybrid wedge plasmonic (LRHWP) waveguide composed of two identical dielectric nanowires symmetrically placed on two opposed wedges of a diamond shaped metal wire. With strong coupling between the dielectric nanowire mode and long-range surface plasmon polariton (SPP) mode, both deep subwav...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06870
更新日期:2014-11-03 00:00:00
abstract::Identification of different isomer structures of atomic and molecular clusters has long been a challenging task in the field of cluster science. Here we present a three-dimensional (3D) assignment method, combining the energy (1D) and simulated (2D) spectra to assure the assignment of the global minimum structure. Thi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17738
更新日期:2015-12-03 00:00:00
abstract::Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases, however, can provide patients and carers with the chance of early intervention, bet...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62922-y
更新日期:2020-04-28 00:00:00
abstract::Electrochemically generated bactericidal compounds have been shown to eradicate bacterial lawn biofilms through electroceutical treatment. However, the ultrastructure of biofilms exposed to these species has not been studied. Moreover, it is unknown if the efficacy of electroceutical treatment extends to antibiotic-re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66823-y
更新日期:2020-06-18 00:00:00
abstract::Cucumber is an agriculturally and economically important vegetable crop worldwide. Fruit flesh thickness is an important trait for cucumber and also a central determinant of yield, yet little is known about the underlying mechanism of this trait. In this study, bulked segregant analysis (BSA) combined with specific le...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15829
更新日期:2015-10-28 00:00:00
abstract::Tilapias (family Cichlidae) are of importance in aquaculture and fisheries. Hybridisation and introgression are common within tilapia genera but are difficult to analyse due to limited numbers of species-specific genetic markers. We tested the potential of double digested restriction-site associated DNA (ddRAD) sequen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48339-2
更新日期:2019-09-10 00:00:00
abstract::Tomatoes are known to have ameliorative effects on cardiovascular disease and cancer. The nutritional value of tomatoes can be enhanced by increasing flavonoids content through genetic modification. The regulatory gene PAP1 (production of anthocyanin pigment 1) from Arabidopsis is reported to increase initial flavonoi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12355-x
更新日期:2017-09-28 00:00:00
abstract::Cyclamen persicum (cyclamen) is a commercially valuable, winter-blooming perennial plant. We cloned two cyclamen orthologues of AGAMOUS (AG), CpAG1 and CpAG2, which are mainly expressed in the stamen and carpel, respectively. Cyclamen flowers have 5 petals, but expression of a chimeric repressor of CpAG1 (CpAG1-SRDX) ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02641
更新日期:2013-01-01 00:00:00
abstract::TRPV1 is a polymodal nociceptor for diverse physical and chemical stimuli that interact with different parts of the channel protein. Recent cryo-EM studies revealed detailed channel structures, opening the door for mapping structural elements mediating activation by each stimulus. Towards this goal, here we have combi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33827
更新日期:2016-09-26 00:00:00
abstract::Bacterial pneumonia is a major cause of acute lung injury and acute respiratory distress syndrome, characterized by alveolar barrier disruption. NLRP3 is best known for its ability to form inflammasomes and to regulate IL-1β and IL-18 production in myeloid cells. Here we show that NLRP3 protects the integrity of the a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30943
更新日期:2016-08-01 00:00:00
abstract::Despite technical advances in brain machine interfaces (BMI), for as-yet unknown reasons the ability to control a BMI remains limited to a subset of users. We investigate whether individual differences in BMI control based on motor imagery (MI) are related to differences in MI ability. We assessed whether differences ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24076
更新日期:2016-04-07 00:00:00
abstract::The long-term survival of relict populations depends on the accessibility of appropriate sites (microrefugia). In recent times, due to the mass extinction of rare species that has resulted from the loss of natural habitats, the question is - Are there any human-made sites that can act as refugial habitats? We examined...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31913
更新日期:2016-08-18 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-69584-w
更新日期:2020-07-29 00:00:00
abstract::Stable isotope labeling is a standard technique for tracing material transfer in molecular, ecological and biogeochemical studies. The main assumption in this approach is that the enrichment with a heavy isotope has no effect on the organism metabolism and growth, which is not consistent with current theoretical and e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44181
更新日期:2017-03-10 00:00:00
abstract::Local translation of membrane proteins in neuronal subcellular domains like soma, dendrites and axon termini is well-documented. In this study, we isolated the electrical signaling unit of an axon by dissecting giant axons from mature squids (Dosidicus gigas). Axoplasm extracted from these axons was found to contain r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20684-8
更新日期:2018-02-02 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-64611-2
更新日期:2020-05-01 00:00:00
abstract::Lon is an essential, multitasking AAA(+) protease regulating many cellular processes in species across all kingdoms of life. Altered expression levels of the human mitochondrial Lon protease (hLon) are linked to serious diseases including myopathies, paraplegia, and cancer. Here, we present the first 3D structure of f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33631
更新日期:2016-09-16 00:00:00
abstract::Crop wild relatives are valuable resources for future genetic improvement. Here, we report the de novo genome assembly of Musa itinerans, a disease-resistant wild banana relative in subtropical China. The assembled genome size was 462.1 Mb, covering 75.2% of the genome (615.2Mb) and containing 32, 456 predicted protei...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31586
更新日期:2016-08-17 00:00:00
abstract::Since the hemorrhage in severe dengue seems to be primarily related to the defect of the platelet, the possibility that dengue virus (DENV) is selectively tropic for one of its surface receptors was investigated. Flow cytometric data of DENV-infected megakaryocytic cell line superficially expressing human glycoprotein...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20914-z
更新日期:2018-02-09 00:00:00
abstract::Short-wavelength luminescence is essential for high-performance optoelectronic device applications. There have been efforts to obtain intense ultraviolet (UV) emission by encapsulating ZnO one-dimensional (1D) nanostructures with materials such as ZnS. However, the encapsulation of ZnS 1D nanostructures with ZnO has n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13556-0
更新日期:2017-10-12 00:00:00
abstract::The development of novel small molecule inhibitors of the cancer-associated tropomyosin 3.1 (Tpm3.1) provides the ability to examine the metabolic function of specific actin filament populations. We have determined the ability of these anti-Tpm (ATM) compounds to regulate glucose metabolism in mice. Acute treatment (1...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22946-x
更新日期:2018-03-15 00:00:00