Abstract：
:Stable isotope labeling is a standard technique for tracing material transfer in molecular, ecological and biogeochemical studies. The main assumption in this approach is that the enrichment with a heavy isotope has no effect on the organism metabolism and growth, which is not consistent with current theoretical and empirical knowledge on kinetic isotope effects. Here, we demonstrate profound changes in growth dynamics of the green alga Raphidocelis subcapitata grown in 15N-enriched media. With increasing 15N concentration (0.37 to 50 at%), the lag phase increased, whereas maximal growth rate and total yield decreased; moreover, there was a negative relationship between the growth and the lag phase across the treatments. The latter suggests that a trade-off between growth rate and the ability to adapt to the high 15N environment may exist. Remarkably, the lag-phase response at 3.5 at% 15N was the shortest and deviated from the overall trend, thus providing partial support to the recently proposed Isotopic Resonance hypothesis, which predicts that certain isotopic composition is particularly favorable for living organisms. These findings confirm the occurrence of KIE in isotopically enriched algae and underline the importance of considering these effects when using stable isotope labeling in field and experimental studies.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Andriukonis E,Gorokhova Edoi
10.1038/srep44181subject
Has Abstractpub_date
2017-03-10 00:00:00pages
44181issn
2045-2322pii
srep44181journal_volume
7pub_type
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07112-z
更新日期：2017-07-31 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-11-14 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2020-02-20 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-03-09 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2017-01-17 00:00:00
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pub_type： 杂志文章
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更新日期：2016-01-19 00:00:00
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pub_type： 杂志文章
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更新日期：2020-10-20 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2015-08-17 00:00:00
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pub_type： 杂志文章
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更新日期：2019-08-14 00:00:00
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pub_type： 杂志文章
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更新日期：2014-10-07 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27119
更新日期：2016-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-12-27 00:00:00
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-02-10 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2012-01-01 00:00:00
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journal_title：Scientific reports
pub_type： 已发布勘误
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2015-08-27 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-05-10 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-02-05 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65372-8
更新日期：2020-05-26 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-10-18 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-07-14 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2018-11-07 00:00:00
