Abstract:
:This case-control study was designed to determine whether males who were exposed to diethylstilboestrol (DES) in utero are at increased risk of testicular cancer. Questionnaires were completed for 79 residents of Connecticut, who were diagnosed with primary cancer of the testes between 1945 and approximately six months into 1980. An equal number of matched controls drawn from birth certificate records available from the Connecticut State Department of Health Services also submitted questionnaires. Information included data on past medical conditions of subjects and obstetrical history of mothers. The major finding of this study was a statistically significant elevated risk for premature birth for the testicular cancer cases. The study failed to show that DES increased the risk for testicular cancer. However, in view of the findings from previous human and animal studies of such abnormalities as undescended and hypoplastic testes as well as the consideration that only the earliest exposed birth cohort has reached the age of substantial cancer risk, it would seem prudent for any male who has been prenatally exposed to DES to seek medical follow-up.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Gershman ST,Stolley PDdoi
10.1093/ije/17.4.738subject
Has Abstractpub_date
1988-12-01 00:00:00pages
738-42issue
4eissn
0300-5771issn
1464-3685journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Associations between soy, dairy intakes and breast cancer risk are inconsistent. No studies exist with large numbers of dairy consumers and soy consumers to assess mutual confounding. METHODS:The study cohort contains 52 795 North American women, initially free of cancer, followed for 7.9 years (29.7% were ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyaa007
更新日期:2020-10-01 00:00:00
abstract::The relationship between risk of cervical neoplasia and various sociodemographic, reproductive and sexual characteristics was studied in 126 women (cases) with an abnormal Papanicolaou test finding and 1914 controls seen at the same clinic in which cases were detected but showing no evidence of cervical neoplasia. All...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/15.4.477
更新日期:1986-12-01 00:00:00
abstract::It is a long-standing belief that the size of the difference between the poor (lower social groups) and the rich (higher social groups) in health outcomes will vary according to the characteristics of the area. However typical approaches to analyses of this kind of question violate standard statistical assumption. The...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.1.251
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:To examine whether induced abortion increases the risk of low birthweight in subsequent singleton live births. METHODS:Cohort study using the Danish Medical Birth Registry (MBR), the Hospital Discharge Registry (HDR), and the Induced Abortion Registry (IAR). All women who had their first pregnancy during 19...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/29.1.100
更新日期:2000-02-01 00:00:00
abstract::Although disorders of the prostate are among the most prevalent problems in elderly males, little is known about their epidemiological characteristics. The 1986 Barcelona Health Interview Survey (BHIS), a cross-sectional study of a random sample of the noninstitutionalized population of the city, was used to estimate ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.5.959
更新日期:1992-10-01 00:00:00
abstract::Mildmay Uganda (MUg), an HIV treatment centre near Kampala, the capital of Uganda, has entered into a memorandum of understanding to collaborate with Canadian researchers at the University of Ottawa to develop their research programme and develop an observational cohort database (the MUg observational cohort). The pri...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dys170
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:A central pattern of body fat is recognized as a risk indicator of cardiovascular diseases in adulthood. The development of this body fat pattern from childhood into adulthood however, remains to be explored. METHODS:The development of two trunk skinfolds (subscapular; supra-iliac), two extremity skinfolds ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/25.6.1162
更新日期:1996-12-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/dyy240
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:A number of studies have reported that increased consumption of natural products reduced the risk of cancer. Our previous case-control studies have shown a significant reduction in the risk of cancer development among those who regularly consumed ginseng. We conducted a prospective cohort study to evaluate t...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/27.3.359
更新日期:1998-06-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.1.32
更新日期:1985-03-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/24.1.8
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:Urbanization in developing countries is usually accompanied by migration to cities, making it a challenge to unpack the independent relationships between migration, urbanization and health, particularly in the presence of health-selective migration. Since 1978, unprecedented planned urbanization has taken pl...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz031
更新日期:2019-08-01 00:00:00
abstract::The relationship between body fat and different aspects of glucose tolerance was examined within the Zutphen Study. In 1970 an oral glucose tolerance test (OGTT) was carried out in 404 non-diabetic men aged 50-70. None of the subjects could be classified as having impaired glucose tolerance. Body mass index (BMI), sub...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/18.2.368
更新日期:1989-06-01 00:00:00
abstract::A generalized least squares regression approach is proposed for the analysis of data arising from experimental studies involving cluster randomization and non-experimental studies in which the major treatment factor corresponds to a characteristic which applies at the cluster level. This approach is more flexible than...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.2.322
更新日期:1985-06-01 00:00:00
abstract:BACKGROUND:This article examines whether the neighbourhood environment influences intermediate cardiovascular disease (CVD) risk factors, such as obesity (body mass index [BMI]), and lifestyle factors, such as no physical activity and smoking, when adjusted for the individual socioeconomic status (SES). METHODS:The st...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/28.5.841
更新日期:1999-10-01 00:00:00
abstract::This paper provides a brief overview to four major types of causal models for health-sciences research: Graphical models (causal diagrams), potential-outcome (counterfactual) models, sufficient-component cause models, and structural-equations models. The paper focuses on the logical connections among the different typ...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/31.5.1030
更新日期:2002-10-01 00:00:00
abstract::Blood pressure levels were measured in 626 children (138 Japanese, 477 Bolivian and 11 of mixed blood) in a Japanese agricultural settlement in Bolivia. Systolic (SBP) and diastolic (DBP) blood pressure was higher in Japanese children than in Bolivian children at each measured age by 4.09 mmHg (P = 0.0001) and 2.25 mm...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/18.1.100
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:There is considerable interest in the possible role of nitrate in gastric carcinogenesis, but little information on nitrate intake around the world. This is the first study to give comprehensive standardised data on nitrate excretion as a marker of intake, using 48 worldwide population samples. METHODS:Urin...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/25.3.505
更新日期:1996-06-01 00:00:00
abstract::It is usually necessary to estimate repeatability of a self-administered questionnaire from responses by subjects on just two occasions. It is shown that it is not possible to estimate false positive and false negative classification rates separately, but that an average correct classification can be calculated. This ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.1.121
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:In sub-Saharan Africa, the prevalence of orphanhood among children has been greatly exacerbated by the HIV/AIDS pandemic. If orphanhood harms a child's development and these effects perpetuate into adult life, then the African orphan crisis could seriously jeopardize the continent's future generations. Wheth...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyn197
更新日期:2009-04-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/8.4.365
更新日期:1979-12-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/12.2.238
更新日期:1983-06-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/4.1.37
更新日期:1975-03-01 00:00:00
abstract:BACKGROUND:Data from the Carolina Breast Cancer Study, a population-based, case-control study of breast cancer in African-American and white women residents of North Carolina, were evaluated to determine whether specific aspects of lactation are associated with a reduction in the risk of breast cancer. METHODS:Analyse...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/28.3.396
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Accumulating evidence suggests that aspirin use may improve survival in cancer patients, however, for endometrial cancer, epidemiological evidence is limited and results are equivocal. In a nationwide cohort study, we examined the association between post-diagnostic low-dose aspirin use and endometrial cance...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz253
更新日期:2020-02-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.2.273
更新日期:1992-04-01 00:00:00
abstract::In a population-based cohort study in Southern Brazil, 87.3% of 5914 liveborn infants were followed for over 12 months. The 215 infant deaths occurring in this cohort were studied in relation to birthweight, gestational age and socioeconomic status. Causes of death were ascertained through the review of case notes and...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.2.239
更新日期:1987-06-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/24.4.655
更新日期:1995-08-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.1.107
更新日期:1993-02-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.5.818
更新日期:1993-10-01 00:00:00