Abstract:
:The large phenotypic variation in the olfactory bulb may be related to heterogeneity in the progenitor cells. Accordingly, the progeny of subventricular zone (SVZ) progenitor cells that are destined for the olfactory bulb is of particular interest, specifically as there are many facets of these progenitors and their molecular profiles remain unknown. Using modified StarTrack genetic tracing strategies, specific SVZ progenitor cells were targeted in E12 mice embryos, and the cell fate of these neural progenitors was determined in the adult olfactory bulb. This study defined the distribution and the phenotypic diversity of olfactory bulb interneurons from specific SVZ-progenitor cells, focusing on their spatial pallial origin, heterogeneity, and genetic profile.
journal_name
Genes (Basel)journal_title
Genesauthors
Sánchez-González R,Figueres-Oñate M,Ojalvo-Sanz AC,López-Mascaraque Ldoi
10.3390/genes11030305subject
Has Abstractpub_date
2020-03-13 00:00:00issue
3issn
2073-4425pii
genes11030305journal_volume
11pub_type
杂志文章相关文献
Genes文献大全abstract::In China, the production for duck meat is second only to that of chicken, and the demand for duck meat is also increasing. However, there is still unclear on the internal mechanism of regulating skeletal muscle growth and development in duck. This study aimed to identity candidate genes related to growth of duck skele...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11101228
更新日期:2020-10-20 00:00:00
abstract::Cancers can be categorized into two groups: those whose frequency increases with age, and those resulting from errors during mammalian development. The first group is linked to DNA replication through the accumulation of genetic mutations that occur during proliferation of developmentally acquired stem cells that give...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes8020045
更新日期:2017-01-25 00:00:00
abstract::Acquisition of mobile elements by horizontal gene transfer can play a major role in bacterial adaptation and genome evolution by providing traits that contribute to bacterial fitness. However, gaining foreign DNA can also impose significant fitness costs to the host bacteria and can even produce detrimental effects. T...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes11020142
更新日期:2020-01-29 00:00:00
abstract::Genetic variations introduced via introgression from Western to Chinese pigs have contributed to the performance of Chinese breeds in traits such as growth rate and feed conversion efficiency. However, little is known about the underlying genomic changes that occurred during introgression and the types of traits affec...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11030275
更新日期:2020-03-04 00:00:00
abstract::Protein sequence, structure, and function are inherently linked through evolution and population genetics. Our knowledge of protein structure comes from solved structures in the Protein Data Bank (PDB), our knowledge of sequence through sequences found in the NCBI sequence databases (http://www.ncbi.nlm.nih.gov/), and...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes2040748
更新日期:2011-10-28 00:00:00
abstract::Bacterial fruit blotch (BFB) causes losses in melon marketable yield. However, until now, there has been no information about the genetic loci responsible for resistance to the disease or their pattern of inheritance. We determined the inheritance pattern of BFB resistance from a segregating population of 491 F2 indiv...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11020220
更新日期:2020-02-19 00:00:00
abstract::Inherited retinal degenerations are the leading cause of blindness in the working population. X-linked retinitis pigmentosa (XLRP), caused by mutations in the Retinitis pigmentosa GTPase regulator (RPGR) gene is one of the more severe forms, and female carriers of RPGR mutations have a variable presentation. A retrosp...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes9120643
更新日期:2018-12-18 00:00:00
abstract::Model-based clustering with finite mixture models has become a widely used clustering method. One of the recent implementations is MCLUST. When objects to be clustered are summary statistics, such as regression coefficient estimates, they are naturally associated with estimation errors, whose covariance matrices can o...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11020185
更新日期:2020-02-10 00:00:00
abstract::Testis cords are the embryonic precursors of the seminiferous tubules. Development of testis cords is a key event during embryonic testicular morphogenesis and is regulated by multiple signaling molecules produced by Sertoli cells. However, the exact nature and the cascade of molecular events underlying testis cord de...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10120974
更新日期:2019-11-26 00:00:00
abstract::Bone mineral density (BMD) is of concern in Prader-Willi syndrome (PWS). This study compared responses to a physical activity intervention in bone parameters and remodeling markers in youth with PWS (n = 45) and youth with non-syndromic obesity (NSO; n = 66). Measurements occurred at baseline (PRE) and after 24 weeks ...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11090984
更新日期:2020-08-24 00:00:00
abstract::Segments of the genome enriched in repetitive sequences still present a challenge and are omitted in genome assemblies. For that reason, the exact composition of DNA sequences underlying the heterochromatic regions and the active centromeres are still unexplored for many organisms. The centromere is a crucial region o...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11060695
更新日期:2020-06-24 00:00:00
abstract::Recently, microfluidic technologies have attracted an enormous amount of interest as potential new tools for a large range of applications including materials synthesis, chemical and biological detection, drug delivery and screening, point-of-care diagnostics, and in-the-field analysis. Their ability to handle extreme...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes9060283
更新日期:2018-06-05 00:00:00
abstract::This study investigated the effects of dietary terrestrial animal and plant proteins on the intestinal transcriptomes of yellowtail kingfish (YTK), Seriola lalandi, an ecologically and economically important marine species in Australia. Five diets containing fish meal (FM), poultry by-product meal (PBM), blood meal (B...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11060621
更新日期:2020-06-05 00:00:00
abstract::The scale of genetic methods are presently being expanded: forensic genetic assays previously were limited to tens of loci, but now technologies allow for a transition to forensic genomic approaches that assess thousands to millions of loci. However, there are subtle distinctions between genetic assays and their genom...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes12020185
更新日期:2021-01-27 00:00:00
abstract::Yersinia enterocolitica is the causative agent of yersiniosis, a zoonotic disease of growing epidemiological importance with significant consequences for public health. This pathogenic species has been intensively studied for many years. Six biotypes (1A, 1B, 2, 3, 4, 5) and more than 70 serotypes of Y. enterocolitica...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes9050235
更新日期:2018-05-03 00:00:00
abstract::Ferns are a representative clade in plant evolution although underestimated in the genomic era. Ceratopteris richardii is an emergent model for developmental processes in ferns, yet a complete scheme of the different growth stages is necessary. Here, we present a developmental analysis, at the tissue and cellular leve...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11121455
更新日期:2020-12-04 00:00:00
abstract::EuAP2 genes are well-known for their role in flower development, a legacy of the founding member of this subfamily of transcription factors, whose mutants lacked petals in Arabidopsis. However, studies of euAP2 genes in several species have accumulated evidence highlighting the diverse roles of euAP2 genes in other as...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes10120994
更新日期:2019-12-01 00:00:00
abstract::Dwarfism is a condition defined by low harvest weight in fish, but also results in strange body figures which may have potential for the selective breeding of new ornamental fish strains. The objectives of this study are to reveal the physiological causes of dwarfism and identify the genetic loci controlling this trai...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10060418
更新日期:2019-05-30 00:00:00
abstract::DNA methylation, catalyzed by DNA methyltransferases (DNMTs), is an epigenetic mark that needs to be faithfully replicated during mitosis in order to maintain cell phenotype during successive cell divisions. This epigenetic mark is located on the 5'-carbon of the cytosine mainly within cytosine⁻phosphate⁻guanine (CpG)...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes10010065
更新日期:2019-01-18 00:00:00
abstract::Alterations in the tumor suppressor phosphatase and tensin homolog (PTEN) occur in a substantial proportion of solid tumors. These events drive tumorigenesis and tumor progression. Given its central role as a downregulator of the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway, PTEN i...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes11070719
更新日期:2020-06-28 00:00:00
abstract::Cultivation of faba bean (Vicia faba L.) in Tunisia is largely based on improved varieties of the crop. However, a few farmers continue to produce local cultivars or landraces. The National Gene Bank of Tunisia (NGBT) recently launched a collection project for faba bean landraces, with special focus on the regions of ...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11020236
更新日期:2020-02-24 00:00:00
abstract::Croatian viticulture was most extensive at the beginning of the 20th century, when about 400 varieties were in use. Autochthonous varieties are the result of spontaneous hybridization from the pre-phylloxera era and are still cultivated today on about 35 % of vineyard area, while some exist only in repositories. We pr...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11070737
更新日期:2020-07-02 00:00:00
abstract::Xeroderma pigmentosum group C (XPC) is a key component of the nucleotide excision repair (NER) pathway. Dysfunctional XPC protein may impair NER-mediated DNA repair capacity and further lead to genomic instability and carcinogenesis. Two common nonsynonymous polymorphisms in the XPC gene, Lys939Gln (rs2228001 A > C) a...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes7100073
更新日期:2016-09-24 00:00:00
abstract::Several species of herbivores feed on maize in field and storage setups, making the development of multiple insect resistance a critical breeding target. In this study, an association mapping panel of 341 tropical maize lines was evaluated in three field environments for resistance to fall armyworm (FAW), whilst bulke...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11060689
更新日期:2020-06-24 00:00:00
abstract::Smoltification and early seawater phase are critical developmental periods with physiological and biochemical changes in Atlantic salmon that facilitates survival in saltwater. MicroRNAs (miRNAs) are known to have important roles in development, but whether any miRNAs are involved in regulation of gene expression duri...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11091059
更新日期:2020-09-08 00:00:00
abstract::High-throughput technologies have allowed researchers to obtain genome-wide data from a wide array of experimental model systems. Unfortunately, however, new data generation tends to significantly outpace data re-utilization, and most high throughput datasets are only rarely used in subsequent studies or to generate n...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10060423
更新日期:2019-06-01 00:00:00
abstract::The development of high-throughput sequencing technologies and screening of big patient cohorts with familial and sporadic amyotrophic lateral sclerosis (ALS) led to the identification of a significant number of genetic variants, which are sometimes difficult to interpret. The American College of Medical Genetics and ...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11101123
更新日期:2020-09-24 00:00:00
abstract::Ehlers-Danlos syndrome (EDS) comprises clinically heterogeneous connective tissue disorders with diverse molecular etiologies. The 2017 International Classification for EDS recognized 13 distinct subtypes caused by pathogenic variants in 19 genes mainly encoding fibrillar collagens and collagen-modifying or processing...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10020135
更新日期:2019-02-12 00:00:00
abstract::Pyrethroid resistance in major malaria vectors such as Anopheles funestus threatens malaria control efforts in Africa. Cytochrome P450-mediated metabolic resistance is best understood for CYP6P9 genes in southern Africa in An. funestus. However, we do not know if this resistance mechanism is spreading across Africa an...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11111314
更新日期:2020-11-05 00:00:00
abstract::Alternative splicing is a well-studied gene regulatory mechanism that produces biological diversity by allowing the production of multiple protein isoforms from a single gene. An involvement of alternative splicing in the key biological signalling Hippo pathway is emerging and offers new therapeutic avenues. This revi...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes9030161
更新日期:2018-03-13 00:00:00