Abstract:
:EuAP2 genes are well-known for their role in flower development, a legacy of the founding member of this subfamily of transcription factors, whose mutants lacked petals in Arabidopsis. However, studies of euAP2 genes in several species have accumulated evidence highlighting the diverse roles of euAP2 genes in other aspects of plant development. Here, we emphasize other developmental roles of euAP2 genes in various species and suggest a shift from regarding euAP2 genes as just flowering genes to consider the global role they may be playing in plant development. We hypothesize that their almost universal expression profile and pleiotropic effects of their mutation suggest their involvement in fundamental plant development processes.
journal_name
Genes (Basel)journal_title
Genesauthors
Solomon CU,Drea Sdoi
10.3390/genes10120994subject
Has Abstractpub_date
2019-12-01 00:00:00issue
12issn
2073-4425pii
genes10120994journal_volume
10pub_type
杂志文章,评审相关文献
Genes文献大全abstract::Familial hypercholesterolemia (FH) is a common autosomal codominant disorder, characterized by elevated low-density lipoprotein cholesterol levels causing premature atherosclerotic cardiovascular disease. About 2900 variants of LDLR, APOB, and PCSK9 genes potentially associated with FH have been described earlier. Nev...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes12010066
更新日期:2021-01-06 00:00:00
abstract::DNA methylation patterns have been shown to change throughout the normal aging process. Several studies have found epigenetic aging markers using age predictors, but these studies only focused on blood-specific or tissue-common methylation patterns. Here, we constructed nine tissue-specific age prediction models using...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10110888
更新日期:2019-11-04 00:00:00
abstract::Roan (Rn) horses show a typical seasonal change of color. Their body is covered with colored and white hair. We performed a descriptive statistical analysis of breeding records of Icelandic horses to challenge the hypothesis of roan being lethal in utero under homozygous condition. The roan to non-roan ratio of foals ...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11060680
更新日期:2020-06-22 00:00:00
abstract::Chlorella is a popular microalga with robust physiological and biochemical characteristics, which can be cultured under various conditions. The exploration of the small RNA content of Chlorella could improve strategies for the enhancement of metabolite production from this microalga. In this study, stress was introduc...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11101131
更新日期:2020-09-25 00:00:00
abstract::Inherited retinal degenerations are the leading cause of blindness in the working population. X-linked retinitis pigmentosa (XLRP), caused by mutations in the Retinitis pigmentosa GTPase regulator (RPGR) gene is one of the more severe forms, and female carriers of RPGR mutations have a variable presentation. A retrosp...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes9120643
更新日期:2018-12-18 00:00:00
abstract::Autoimmune blistering dermatoses (ABDs) are characterized by autoantibodies to keratinocyte surface antigens and molecules within the dermal-epidermal junction causing disruption of skin integrity. The affinity of Fc receptors (FcRs) causing an autoimmune response in ABDs may vary based on single-nucleotide polymorphi...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11040371
更新日期:2020-03-30 00:00:00
abstract::Rapeseed contains glucosinolates, a toxic group of sulfur-containing glucosides, which play critical roles in defense against herbivores and microbes. However, the presence of glucosinolates in rapeseed reduces the value of the meal as feed for livestock. We performed association mapping of seed glucosinolate (GS) con...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes6041215
更新日期:2015-11-18 00:00:00
abstract::Dwarfism is a condition defined by low harvest weight in fish, but also results in strange body figures which may have potential for the selective breeding of new ornamental fish strains. The objectives of this study are to reveal the physiological causes of dwarfism and identify the genetic loci controlling this trai...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10060418
更新日期:2019-05-30 00:00:00
abstract::The spectrum of modern horse populations encompasses populations with a long history of development in isolation and relatively recently formed types. To increase our understanding of the evolutionary history and provide information on how to optimally conserve or improve these populations with varying development and...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10060480
更新日期:2019-06-25 00:00:00
abstract::The 2019 "Personal Genomes: Accessing, Sharing and Interpretation" conference (Hinxton, UK, 11-12 April 2019) brought together geneticists, bioinformaticians, clinicians and ethicists to promote openness and ethical sharing of personal genome data while protecting the privacy of individuals. The talks at the conferenc...
journal_title:Genes
pub_type:
doi:10.3390/genes10090643
更新日期:2019-08-25 00:00:00
abstract::microRNA (miRNA) activity and regulation are of increasing interest as new therapeutic targets. Traditional approaches to assess miRNA levels in cells rely on RNA sequencing or quantitative PCR. While useful, these approaches are based on RNA extraction and cannot be applied in real-time to observe miRNA activity with...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes9060305
更新日期:2018-06-19 00:00:00
abstract::MYO6 is known as a genetic cause of autosomal dominant and autosomal recessive inherited hearing loss. In this study, to clarify the frequency and clinical characteristics of hearing loss caused by MYO6 gene mutations, a large-scale genetic analysis of Japanese patients with hearing loss was performed. By means of mas...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11030273
更新日期:2020-03-04 00:00:00
abstract::Long non-coding (lnc) RNAs serve a multitude of functions in cells. NEAT1 RNA is a highly abundant 4 kb lncRNA in nuclei, and coincides with paraspeckles, nuclear domains that control sequestration of paraspeckle proteins. We examined NEAT1 RNA levels and its function in 3T3-L1 cells during differentiation to adipocyt...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes5041050
更新日期:2014-11-27 00:00:00
abstract::Colorectal cancer is the fourth most common neoplasia in Europe, where it accounts for 28.2 new cases per 100,000 inhabitants. In an effort to decrease the incidence of this disease, various prevention measures are being studied, one of which are anthocyanin-rich foods. Anthocyanins are potent antioxidant flavonoids m...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes9030133
更新日期:2018-03-01 00:00:00
abstract::Overweight and obesity are major problems in today's society, driving the prevalence of diabetes and its related complications. It is important to understand the molecular mechanisms underlying the chronic complications in diabetes in order to develop better therapeutic approaches for these conditions. Some of the mos...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes5040926
更新日期:2014-09-29 00:00:00
abstract::Several transcription factors (TFs) coordinate to regulate expression of specific genes at the transcriptional level. In Arabidopsis thaliana it is estimated that approximately 10% of all genes encode TFs or TF-like proteins. It is important to identify target genes that are directly regulated by TFs in order to under...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes5041115
更新日期:2014-12-19 00:00:00
abstract::The transcription factor PAX6 is essential in ocular development in vertebrates, being considered the master regulator of the eye. During eye development, it is essential for the correct patterning and formation of the multi-layered optic cup and it is involved in the developing lens and corneal epithelium. In adultho...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes10121050
更新日期:2019-12-17 00:00:00
abstract::Hepatic oval cells (HOCs) are considered the progeny of the intrahepatic stem cells that are found in a small population in the liver after hepatocyte proliferation is inhibited. Due to their small number, isolation and capture of these cells constitute a challenging task for immunosensor technology. This work describ...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes9020089
更新日期:2018-02-14 00:00:00
abstract::In forensics, mitochondrial DNA (mtDNA) analysis is foremost applied to rootless hairs often lacking detectable nuclear DNA. Sanger sequencing is the routine mtDNA method in most forensic laboratories, even though interpretation of mixed samples and heteroplasmic sites can be challenging. Individuals may hold cells wi...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11111355
更新日期:2020-11-16 00:00:00
abstract::This review looks back at five decades of research into genetic susceptibility to colorectal cancer (CRC) and the insights these studies have provided. Initial evidence of a genetic basis of CRC stems from epidemiological studies in the 1950s and is further provided by the existence of multiple dominant predisposition...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes5020270
更新日期:2014-03-27 00:00:00
abstract::Despite worldwide prevention programs, the incidence for cutaneous melanoma is continuously increasing. Mucosal melanoma (MM) represents a rare but highly aggressive phenotype of common melanoma with predilection in the sinonasal system. Far away from ultraviolet sun exposure, the molecular mechanisms underlying tumor...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes8120384
更新日期:2017-12-13 00:00:00
abstract::Cyclocarya paliurus (Batal.) Iljinskaja, a unique species growing in southern China, is a multi-function tree species with medicinal, healthcare, material, and ornamental values. So far, sexual reproduction is the main method for extensive cultivation of C. paliurus plantations, but this is limited by low seed plumpne...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10100818
更新日期:2019-10-17 00:00:00
abstract::Transfer RNAs (tRNAs) are abundant small non-coding RNAs that are crucially important for decoding genetic information. Besides fulfilling canonical roles as adaptor molecules during protein synthesis, tRNAs are also the source of a heterogeneous class of small RNAs, tRNA-derived small RNAs (tsRNAs). Occurrence and th...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes9120607
更新日期:2018-12-05 00:00:00
abstract::Preimplantation genetic testing (PGT) has evolved into a well-established alternative to invasive prenatal diagnosis, even though genetic testing of single or few cells is quite challenging. PGT-M is in theory available for any monogenic disorder for which the disease-causing locus has been unequivocally identified. I...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes11080871
更新日期:2020-07-31 00:00:00
abstract::In angiosperms, meiotic failure coupled with the formation of genetically unreduced gametophytes in ovules (apomeiosis) constitute major components of gametophytic apomixis. These aberrant developmental events are generally thought to be caused by mutation. However, efforts to locate the responsible mutations have fai...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11121449
更新日期:2020-12-02 00:00:00
abstract::Pseudomonas savastanoi pv. savastanoi is the causal agent of Olive knot disease, relying on the Type Three Secretion System (TTSS) for its pathogenicity. In this regard, nothing was known about the two other pathovars belonging to this species, pv. nerii and pv. fraxini, characterized by a different host range. Here w...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes2040957
更新日期:2011-11-25 00:00:00
abstract::The liver plays a key role in metabolism and affects pig production. However, the functional annotation of noncoding regions of the pig liver remains poorly understood. We revealed the landscape of cis-regulatory elements and their functional characterization in pig liver. We identified 102,373 cis-regulatory elements...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes10050348
更新日期:2019-05-07 00:00:00
abstract::Genome wide association studies (GWAS) are a well established methodology to identify genomic variants and genes that are responsible for traits of interest in all branches of the life sciences. Despite the long time this methodology has had to mature the reliable detection of genotype-phenotype associations is still ...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11080892
更新日期:2020-08-05 00:00:00
abstract::PPARGC1A rs8192678 G/A (Gly482Ser) and NRF1 rs6949152 A/G polymorphisms have been associated with endurance athlete status, endurance performance phenotypes, and certain health-related markers of different pathologies such as metabolic syndrome, diabetes, and dyslipidemia. We hypothesized that they could be considered...
journal_title:Genes
pub_type: 杂志文章
doi:10.3390/genes11091012
更新日期:2020-08-27 00:00:00
abstract::The transition from a dormant to a germinating seed represents a crucial developmental switch in the life cycle of a plant. Subsequent transition from a germinating seed to an autotrophic organism also requires a robust and multi-layered control. Seed germination and seedling growth are multistep processes, involving ...
journal_title:Genes
pub_type: 杂志文章,评审
doi:10.3390/genes12010052
更新日期:2020-12-31 00:00:00