当前位置： SCI文献检索 > Genes期刊下所有文献 > A 24-Week Physical Activity Intervention Increases Bone Mineral Content without Changes in Bone Markers in Youth with PWS.

A 24-Week Physical Activity Intervention Increases Bone Mineral Content without Changes in Bone Markers in Youth with PWS.

Abstract：

:Bone mineral density (BMD) is of concern in Prader-Willi syndrome (PWS). This study compared responses to a physical activity intervention in bone parameters and remodeling markers in youth with PWS (n = 45) and youth with non-syndromic obesity (NSO; n = 66). Measurements occurred at baseline (PRE) and after 24 weeks (POST) of a home-based active games intervention with strengthening and jumping exercises (intervention group = I) or after a no-intervention period (control group = C). Dual x-ray absorptiometry scans of the hip and lumbar spine (L1-L4) determined BMD and bone mineral content (BMC). Bone markers included fasting bone-specific alkaline phosphatase (BAP) and C-terminal telopeptide of type I collagen (CTx). Both I and C groups increased their hip BMD and BMC (p < 0.001). Youth with PWS-I increased their spine BMC from PRE to POST (p < 0.001) but not youth with PWS-C (p = 1.000). Youth with NSO (I and C) increased their spine BMC between PRE and POST (all p < 0.001). Youth with PWS showed lower BAP (108.28 ± 9.19 vs. 139.07 ± 6.41 U/L; p = 0.006) and similar CTx (2.07 ± 0.11 vs.1.84 ± 0.14 ng/dL; p = 0.193) than those with NSO regardless of time. Likely, the novelty of the intervention exercises for those with PWS contributed to gains in spine BMC beyond growth. Bone remodeling markers were unaltered by the intervention.

journal_name

Genes (Basel)

journal_title

Genes

authors

Rubin DA,Wilson KS,Orsso CE,Gertz ER,Haqq AM,Castner DM,Dumont-Driscoll M

doi

10.3390/genes11090984

subject

Has Abstract

pub_date

2020-08-24 00:00:00

issue

9

issn

2073-4425

pii

genes11090984

journal_volume

11

pub_type

杂志文章

相关文献

Genes文献大全
  • Target-Genes Reveal Species and Genotypic Specificity of Anthocyanin Pigmentation in Citrus and Related Genera.

    abstract：BACKGROUND:Anthocyanin pigmentation characterizes a number of tissues of Citrus and its relatives. The gain and loss of pigmentation is intriguing and is inherited variously among species. METHODS:Citrus germplasm was used to investigate the anthocyanin pigmentation of tissues never before considered, including stamen...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes11070807

    authors： Catalano C,Ciacciulli A,Salonia F,Russo MP,Caruso P,Caruso M,Russo G,Distefano G,Licciardello C

    更新日期：2020-07-16 00:00:00

  • DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in Saccharomyces cerevisiae.

    abstract：:This review discusses a set of experimental results that support the existence of extended strand displacement events during budding yeast lagging strand DNA synthesis. Starting from introducing the mechanisms and factors involved in leading and lagging strand DNA synthesis and some aspects of the architecture of the ...

    journal_title：Genes

    pub_type： 杂志文章,评审

    doi：10.3390/genes10020167

    authors： Giannattasio M,Branzei D

    更新日期：2019-02-21 00:00:00

  • High-Throughput Incubation and Quantification of Agglutination Assays in a Microfluidic System.

    abstract：:In this paper, we present a two-phase microfluidic system capable of incubating and quantifying microbead-based agglutination assays. The microfluidic system is based on a simple fabrication solution, which requires only laboratory tubing filled with carrier oil, driven by negative pressure using a syringe pump. We pr...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes9060281

    authors： Castro D,Conchouso D,Kodzius R,Arevalo A,Foulds IG

    更新日期：2018-06-04 00:00:00

  • ALT: A Multi-Faceted Phenomenon.

    abstract：:One of the hallmarks of cancer cells is their indefinite replicative potential, made possible by the activation of a telomere maintenance mechanism (TMM). The majority of cancers reactivate the reverse transcriptase, telomerase, to maintain their telomere length but a minority (10% to 15%) utilize an alternative lengt...

    journal_title：Genes

    pub_type： 杂志文章,评审

    doi：10.3390/genes11020133

    authors： Sommer A,Royle NJ

    更新日期：2020-01-27 00:00:00

  • Haplotypes of the Ovine Adiponectin Gene and Their Association with Growth and Carcass Traits in New Zealand Romney Lambs.

    abstract：:Adiponectin plays an important role in energy homeostasis and metabolism in mammalian adipose tissue. In this study, the relationship between adiponectin gene (ADIPOQ) haplotypes and variation in growth and carcass traits in New Zealand (NZ) Romney lambs was investigated using General Linear Models (GLMs). Eight haplo...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes8060160

    authors： An Q,Zhou H,Hu J,Luo Y,Hickford JGH

    更新日期：2017-06-12 00:00:00

  • Microbiome Data Accurately Predicts the Postmortem Interval Using Random Forest Regression Models.

    abstract：:Death investigations often include an effort to establish the postmortem interval (PMI) in cases in which the time of death is uncertain. The postmortem interval can lead to the identification of the deceased and the validation of witness statements and suspect alibis. Recent research has demonstrated that microbes pr...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes9020104

    authors： Belk A,Xu ZZ,Carter DO,Lynne A,Bucheli S,Knight R,Metcalf JL

    更新日期：2018-02-16 00:00:00

  • Identification and Analysis of microRNAs in Chlorella sorokiniana Using High-Throughput Sequencing.

    abstract：:Chlorella is a popular microalga with robust physiological and biochemical characteristics, which can be cultured under various conditions. The exploration of the small RNA content of Chlorella could improve strategies for the enhancement of metabolite production from this microalga. In this study, stress was introduc...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes11101131

    authors： Azaman SNA,Satharasinghe DA,Tan SW,Nagao N,Yusoff FM,Yeap SK

    更新日期：2020-09-25 00:00:00

  • Comparative Transcriptome Analysis of Gene Expression Patterns in Tomato Under Dynamic Light Conditions.

    abstract：:Plants grown under highly variable natural light regimes differ strongly from plants grown under constant light (CL) regimes. Plant phenotype and adaptation responses are important for plant biomass and fitness. However, the underlying regulatory mechanisms are still poorly understood, particularly from a transcriptio...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes10090662

    authors： Ding J,Zhao J,Pan T,Xi L,Zhang J,Zou Z

    更新日期：2019-08-29 00:00:00

  • Identification of Loci Controlling the Dwarfism Trait in the White Sailfin Molly (Poecilia latipinna) Using Genome-Wide Association Studies Based on Genotyping-By-Sequencing.

    abstract：:Dwarfism is a condition defined by low harvest weight in fish, but also results in strange body figures which may have potential for the selective breeding of new ornamental fish strains. The objectives of this study are to reveal the physiological causes of dwarfism and identify the genetic loci controlling this trai...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes10060418

    authors： Shao F,Liu J,Ren M,Li J,Bao H,Wu C

    更新日期：2019-05-30 00:00:00

  • The role of bromodomain proteins in regulating gene expression.

    abstract：:Histone modifications are important in regulating gene expression in eukaryotes. Of the numerous histone modifications which have been identified, acetylation is one of the best characterised and is generally associated with active genes. Histone acetylation can directly affect chromatin structure by neutralising char...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes3020320

    authors： Josling GA,Selvarajah SA,Petter M,Duffy MF

    更新日期：2012-05-29 00:00:00

  • RNA-Seq Analyses Identify Additivity as the Predominant Gene Expression Pattern in F1 Chicken Embryonic Brain and Liver.

    abstract：:The superior performance of hybrids to parents, termed heterosis, has been widely utilized in animal and plant breeding programs, but the molecular mechanism underlying heterosis remains an enigma. RNA-Seq provides a novel way to investigate heterosis at the transcriptome-wide level, because gene expression functions ...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes10010027

    authors： Zhuo Z,Lamont SJ,Abasht B

    更新日期：2019-01-07 00:00:00

  • Identification of a Novel Imprinted Transcript in the Porcine GNAS Complex Locus Using Methylome and Transcriptome of Parthenogenetic Fetuses.

    abstract：:Genomic imprinting in domestic animals contributes to the variance of performance traits. However, research remains to be done on large-scale detection of epigenetic landscape of porcine imprinted loci including the GNAS complex locus. The purpose of this study was to generate porcine parthenogenetic fetuses and compr...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes11010096

    authors： Ahn J,Wu H,Lee J,Hwang IS,Yu D,Ahn JS,Lee JW,Hwang S,Lee K

    更新日期：2020-01-14 00:00:00

  • Neo-Domestication of an Interspecific Tetraploid Helianthus annuus × Helianthus tuberous Population That Segregates for Perennial Habit.

    abstract：:Perennial agriculture has been proposed as an option to improve the sustainability of cropping systems, by increasing the efficiency of resource use, while also providing ecosystem services. Neo-domestication, the contemporary domestication of plants that have not previously been used in agriculture, can be used to ge...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes9090422

    authors： Kantar MB,Hüber S,Herman A,Bock DG,Baute G,Betts K,Ott M,Brandvain Y,Wyse D,Stupar RM,Rieseberg LH

    更新日期：2018-08-21 00:00:00

  • A Semi-Supervised Learning Algorithm for Predicting Four Types MiRNA-Disease Associations by Mutual Information in a Heterogeneous Network.

    abstract：:Increasing evidence suggests that dysregulation of microRNAs (miRNAs) may lead to a variety of diseases. Therefore, identifying disease-related miRNAs is a crucial problem. Currently, many computational approaches have been proposed to predict binary miRNA-disease associations. In this study, in order to predict under...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes9030139

    authors： Zhang X,Yin J,Zhang X

    更新日期：2018-03-02 00:00:00

  • Transcriptome Analysis of Landrace Pig Subcutaneous Preadipocytes during Adipogenic Differentiation.

    abstract：:Fat deposition in pigs, which significantly contributes to meat quality, fattening efficiency, reproductive performance, and immunity, is critically affected by preadipocyte adipogenic differentiation. We elucidated adipogenesis in pigs using transcriptome analysis. Preadipocytes from subcutaneous adipose tissue (SAT)...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes10070552

    authors： Zhao X,Chen S,Tan Z,Wang Y,Zhang F,Yang T,Liu Y,Ao H,Xing K,Wang C

    更新日期：2019-07-19 00:00:00

  • A Third MLPH Variant Causing Coat Color Dilution in Dogs.

    abstract：:Altered melanosome transport in melanocytes, resulting from variants in the melanophilin (MLPH) gene, are associated with inherited forms of coat color dilution in many species. In dogs, the MLPH gene corresponds to the D locus and two variants, c.-22G > A (d1) and c.705G > C (d2), leading to the dilution of coat colo...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes11060639

    authors： Van Buren SL,Minor KM,Grahn RA,Mickelson JR,Grahn JC,Malvick J,Colangelo JR,Mueller E,Kuehnlein P,Kehl A

    更新日期：2020-06-10 00:00:00

  • Non-Random Distribution of Reciprocal Translocation Breakpoints in the Pig Genome.

    abstract：:Balanced chromosome rearrangements are one of the main etiological factors contributing to hypoprolificacy in the domestic pig. Amongst domestic animals, the pig is considered to have the highest prevalence of chromosome rearrangements. To date over 200 unique chromosome rearrangements have been identified. The factor...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes10100769

    authors： Donaldson B,Villagomez DAF,Revay T,Rezaei S,King WA

    更新日期：2019-09-30 00:00:00

  • DynSig: Modelling Dynamic Signaling Alterations along Gene Pathways for Identifying Differential Pathways.

    abstract：:Although a number of methods have been proposed for identifying differentially expressed pathways (DEPs), few efforts consider the dynamic components of pathway networks, i.e., gene links. We here propose a signaling dynamics detection method for identification of DEPs, DynSig, which detects the molecular signaling ch...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes9070323

    authors： Shi M,Chong Y,Shen W,Xie XP,Wang HQ

    更新日期：2018-06-27 00:00:00

  • You Had Me at "MAGIC"!: Four Barley MAGIC Populations Reveal Novel Resistance QTL for Powdery Mildew.

    abstract：:Blumeria graminis f. sp. hordei (Bgh), the causal agent of barley powdery mildew (PM), is one of the most important barley leaf diseases and is prevalent in most barley growing regions. Infection decreases grain quality and yields on average by 30%. Multi-parent advanced generation inter-cross (MAGIC) populations comb...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes11121512

    authors： Novakazi F,Krusell L,Jensen JD,Orabi J,Jahoor A,Bengtsson T,On Behalf Of The Ppp Barley Consortium

    更新日期：2020-12-18 00:00:00

  • Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits.

    abstract：:Keratin-associated proteins (KAPs) are structural components of wool and hair fibers. To date, eight high glycine/tyrosine KAP (HGT-KAP) families have been identified in humans, but only three have been identified in sheep. In this study, the putative ovine homolog of the human KAP22-1 gene (KRTAP22-1) was amplified u...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes8010027

    authors： Li S,Zhou H,Gong H,Zhao F,Wang J,Liu X,Luo Y,Hickford JG

    更新日期：2017-01-11 00:00:00

  • Review of the Application of Modern Cytogenetic Methods (FISH/GISH) to the Study of Reticulation (Polyploidy/Hybridisation).

    abstract：:The convergence of distinct lineages upon interspecific hybridisation, including when accompanied by increases in ploidy (allopolyploidy), is a driving force in the origin of many plant species. In plant breeding too, both interspecific hybridisation and allopolyploidy are important because they facilitate introgressi...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes1020166

    authors： Chester M,Leitch AR,Soltis PS,Soltis DE

    更新日期：2010-07-02 00:00:00

  • Kinetic Modeling of DUSP Regulation in Herceptin-Resistant HER2-Positive Breast Cancer.

    abstract：BACKGROUND:HER2 (human epidermal growth factor 2)-positive breast cancer is an aggressive type of breast cancer characterized by the overexpression of the receptor-type protein tyrosine kinase HER2 or amplification of the HER2 gene. It is commonly treated by the drug trastuzumab (Herceptin), but resistance to its actio...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes10080568

    authors： Buiga P,Elson A,Tabernero L,Schwartz JM

    更新日期：2019-07-26 00:00:00

  • Cytogenetics in Arctica islandica (Bivalvia, Arctidae): the Longest Lived Non-Colonial Metazoan.

    abstract：:Due to its extraordinary longevity and wide distribution, the ocean quahog Arctica islandica has become an important species model in both aging and environmental change research. Notwithstanding that, most genetic studies on ocean quahogs have been focused on fishery related, phylogeographic and phylogenetic aspects ...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes9060299

    authors： García-Souto D,Pasantes JJ

    更新日期：2018-06-13 00:00:00

  • Synaptonemal complex length variation in wild-type male mice.

    abstract：:Meiosis yields haploid gametes following two successive divisions of a germ cell in the absence of intervening DNA replication. Balanced segregation of homologous chromosomes in Meiosis I is aided by a proteinaceous structure, the synaptonemal complex (SC). The objective of this study was to determine total average au...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes1030505

    authors： Vranis NM,Van der Heijden GW,Malki S,Bortvin A

    更新日期：2010-12-15 00:00:00

  • Convergent Evolution of the Seed Shattering Trait.

    abstract：:Loss of seed shattering is a key trait in crop domestication, particularly for grain crops. For wild plants, seed shattering is a crucial mechanism to achieve greater fitness, although in the agricultural context, this mechanism reduces harvesting efficiency, especially under dry conditions. Loss of seed shattering wa...

    journal_title：Genes

    pub_type： 杂志文章,评审

    doi：10.3390/genes10010068

    authors： Di Vittori V,Gioia T,Rodriguez M,Bellucci E,Bitocchi E,Nanni L,Attene G,Rau D,Papa R

    更新日期：2019-01-19 00:00:00

  • Comparison of Illumina versus Nanopore 16S rRNA Gene Sequencing of the Human Nasal Microbiota.

    abstract：:Illumina and nanopore sequencing technologies are powerful tools that can be used to determine the bacterial composition of complex microbial communities. In this study, we compared nasal microbiota results at genus level using both Illumina and nanopore 16S rRNA gene sequencing. We also monitored the progression of n...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes11091105

    authors： Heikema AP,Horst-Kreft D,Boers SA,Jansen R,Hiltemann SD,de Koning W,Kraaij R,de Ridder MAJ,van Houten CB,Bont LJ,Stubbs AP,Hays JP

    更新日期：2020-09-21 00:00:00

  • Can Genetic Testing Identify Talent for Sport?

    abstract：:Elite athlete status is a partially heritable trait, as are many of the underpinning physiological, anthropometrical, and psychological traits that contribute to elite performance. In recent years, our understanding of the specific genetic variants that contribute to these traits has grown, such that there is consider...

    journal_title：Genes

    pub_type： 杂志文章,评审

    doi：10.3390/genes10120972

    authors： Pickering C,Kiely J,Grgic J,Lucia A,Del Coso J

    更新日期：2019-11-26 00:00:00

  • Biological Regulatory Network (BRN) Analysis and Molecular Docking Simulations to Probe the Modulation of IP3R Mediated Ca2+ Signaling in Cancer.

    abstract：:Inositol trisphosphate receptor (IP3R) mediated Ca+2 signaling is essential in determining the cell fate by regulating numerous cellular processes, including cell division and cell death. Despite extensive studies about the characterization of IP3R in cancer, the underlying molecular mechanism initiating the cell prol...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes12010034

    authors： Ismatullah H,Jabeen I,Saeed MT

    更新日期：2020-12-29 00:00:00

  • NetR and AttR, Two New Bioinformatic Tools to Integrate Diverse Datasets into Cytoscape Network and Attribute Files.

    abstract：:High-throughput technologies have allowed researchers to obtain genome-wide data from a wide array of experimental model systems. Unfortunately, however, new data generation tends to significantly outpace data re-utilization, and most high throughput datasets are only rarely used in subsequent studies or to generate n...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes10060423

    authors： Halajyan A,Weingart N,Yeahia M,Loza-Coll M

    更新日期：2019-06-01 00:00:00

  • Cell Progeny in the Olfactory Bulb After Targeting Specific Progenitors with Different UbC-StarTrack Approaches.

    abstract：:The large phenotypic variation in the olfactory bulb may be related to heterogeneity in the progenitor cells. Accordingly, the progeny of subventricular zone (SVZ) progenitor cells that are destined for the olfactory bulb is of particular interest, specifically as there are many facets of these progenitors and their m...

    journal_title：Genes

    pub_type： 杂志文章

    doi：10.3390/genes11030305

    authors： Sánchez-González R,Figueres-Oñate M,Ojalvo-Sanz AC,López-Mascaraque L

    更新日期：2020-03-13 00:00:00