Comparative analyses of three swallow species (Aves, Passeriformes, Hirundinidae): Insights on karyotype evolution and genomic organization.

abstract：:The D-genome progenitor of wheat (Triticum aestivum), Aegilops tauschii, possesses numerous genes for resistance to abiotic stresses, including drought. Therefore, information on the genetic architecture of A. tauschii can aid the development of drought-resistant wheat varieties. Here, we evaluated 13 traits in 373 A....

journal_title：Genetics and molecular biology

authors： Qin P,Lin Y,Hu Y,Liu K,Mao S,Li Z,Wang J,Liu Y,Wei Y,Zheng Y

更新日期：2016-07-01 00:00:00

abstract：:This review summarizes the chromosomal changes detected by molecular cytogenetic approaches in esophageal squamous cell carcinoma (ESCC), the ninth most common malignancy in the world. Whole genome analyses of ESCC cell lines and tumors indicated that the most frequent genomic gains occurred at 1, 2q, 3q, 5p, 6p, 7, 8...

journal_title：Genetics and molecular biology

authors： Bellini MF,Silva AE,Varella-Garcia M

更新日期：2010-04-01 00:00:00

abstract：:Cannabinoids, flavonoids, and stilbenoids have been identified in the annual dioecious plant Cannabis sativa L. Of these, the cannabinoids are the best known group of this plant's natural products. Polyketide synthases (PKSs) are responsible for the biosynthesis of diverse secondary metabolites, including flavonoids a...

journal_title：Genetics and molecular biology

authors： Flores-Sanchez IJ,Linthorst HJ,Verpoorte R

更新日期：2010-10-01 00:00:00

abstract：:4-Coumaric acid: coenzyme A ligase (4CL) is a key enzyme in the phenylpropanoid metabolic pathway that regulates the biosynthesis of lignin and flavonoids. Therefore, the study of 4CL is important to explore the accumulation and regulation of metabolites. This study investigated the role that the 4CL2 gene from Dryopt...

journal_title：Genetics and molecular biology

authors： Li SS,Chang Y,Li B,Shao SL,Zhen-Zhu- Z

更新日期：2020-05-20 00:00:00

abstract：:We determined the polymorphism C242T of the aromatase gene (Cyp19) and its allelic frequency, as well as the effect of the variants on productive and reproductive traits in 71 purebred Santa Inês sheep, 13 purebred Brazilian Somali sheep, nine purebred Poll Dorset sheep, and 18 crossbred 1/2 Dorper sheep. The animals ...

journal_title：Genetics and molecular biology

authors： Lôbo AM,Lôbo RN,Paiva SR

更新日期：2009-07-01 00:00:00

abstract：:Heat shock (HS) leads to the activation of molecular mechanisms, known as HS-response, that prevent damage and enhance survival under stress. Plants have a flexible and specialized network of Heat Shock Factors (HSFs), which are transcription factors that induce the expression of heat shock proteins. The present work ...

journal_title：Genetics and molecular biology

authors： Soares-Cavalcanti NM,Belarmino LC,Kido EA,Pandolfi V,Marcelino-Guimarães FC,Rodrigues FA,Pereira GA,Benko-Iseppon AM

更新日期：2012-06-01 00:00:00

abstract：:In the present study, water buffalo MHC (Bubu)-DRB cDNA was cloned and characterized. The 1022 base long-amplified cDNA product encompassed a single open reading frame of 801 bases that coded for 266 amino acids. The Bubu-DRB sequence showed maximum homology with the BoLA-DRB3*0101 allele of cattle. A total of seven a...

journal_title：Genetics and molecular biology

authors： Naskar S,Deb SM,Niranjan SK,Kumar S,Sharma D,Sakaram D,Sharma A

更新日期：2012-01-01 00:00:00

abstract：:Indica and japonica are two main subspecies of Asian cultivated rice (Oryza sativa L.) that differ clearly in morphological and agronomic traits, in physiological and biochemical characteristics and in their genomic structure. However, the proteins and genes responsible for these differences remain poorly characterize...

journal_title：Genetics and molecular biology

authors： Yang Y,Zhu K,Xia H,Chen L,Chen K

更新日期：2014-10-01 00:00:00

abstract：:Autochthonous pig breeds represent an important genetic reserve to be utilized mainly for the production of typical products. To explore its genetic variability, here we present for the first time whole genome sequencing data and SNPs discovered in a male domestic Nero Siciliano pig compared to the last pig reference ...

journal_title：Genetics and molecular biology

authors： D'Alessandro E,Giosa D,Sapienza I,Giuffrè L,Cigliano RA,Romeo O,Zumbo A

更新日期：2019-07-01 00:00:00

abstract：:Glucose-6-phosphate dehydrogenase deficiency (G6PDd) and Duffy-negative blood group are two red blood cells variants that confer protection against malaria. In this study, the distribution of the most common G6PD variants (G6PD*A-, GGPD*A and G6PD Mediterranean) and the major alleles of the Duffy blood group (FY*A, FY...

journal_title：Genetics and molecular biology

authors： Oliveira HSS,Silva ANLMD,Andrade GB,Gaia KC,Costa GLC,Santos ÂKCRD,Guerreiro JF

更新日期：2018-10-01 00:00:00

abstract：:The Morato's Digger Toad, Proceratophrys moratoi, is a critically endangered toad species with a marked population decline in southern Brazilian Cerrado. Despite this, new populations are being discovered, primarily in the northern part of the distribution range, which raises a number of questions with regard to the c...

journal_title：Genetics and molecular biology

authors： Arruda MP,Costa WP,Recco-Pimentel SM

更新日期：2017-04-01 00:00:00

abstract：:The purpose of this study was to investigate whether treatment with electroacupuncture (EA) inhibited mitochondria-dependent apoptosis in annulus fibrosis (AF) cells in a rat model of cervical intervertebral disc degradation induced by unbalanced dynamic and static forces. Forty Sprague-Dawley rats were used in this s...

journal_title：Genetics and molecular biology

authors： Liao J,Ke M,Xu T,Lin L

更新日期：2012-07-01 00:00:00

abstract：:Vitamin D exerts an immuno-modulatory activity on several immune system cells through the vitamin D receptor (VDR). Herein, we verified that age and a therapeutic regimen containing protease inhibitors are associated with failures in antiretroviral therapies (ARVs). In addition, we assessed whether a VDR SNP (rs115688...

journal_title：Genetics and molecular biology

authors： Silva RCD,Alves NMP,Pereira JJS,Coelho AVC,Arraes LC,Brandão LAC,Crovella S,Silva JA

更新日期：2019-04-01 00:00:00

abstract：:Jatropha gossypiifolia L. (Euphorbiaceae), popularly known as cotton-leaf physicnut, is a milky shrub notable for its medicinal properties. The present study aimed to evaluate the toxic, cytotoxic and genotoxic effects of the latex of J. gossypiifolia, using Allium cepa L. as test system. Seeds of A. cepa were exposed...

journal_title：Genetics and molecular biology

authors： de Almeida PM,de Sousa Araújo S,Marin-Morales MA,Benko-Iseppon AM,Brasileiro-Vidal AC

更新日期：2015-03-01 00:00:00

abstract：:The genus Phanaeus is included in the tribe Phanaeini, one of the most diverse tribes within the subfamily Scarabaeinae in terms of chromosomal characteristics. However, so far the species of this genus were not studied with differential cytogenetic techniques, limiting any inference of the probable mechanisms respons...

journal_title：Genetics and molecular biology

authors： Arcanjo A,Cabral-de-Mello DC,Martins C,de Cássia de Moura R,de Souza MJ

更新日期：2013-09-01 00:00:00

abstract：:Switchgrass (Panicum virgatum L.; family Poaceae) is a warm-season C4 perennial grass. Tillering plays an important role in determining the morphology of aboveground parts and the final biomass yield of switchgrass. Auxin distribution in plants can affect a variety of important growth and developmental processes, incl...

journal_title：Genetics and molecular biology

authors： Xu K,Sun F,Wang Y,Shi L,Liu S,Xi Y

更新日期：2016-03-01 00:00:00

abstract：:This study presents evidence, using sequences of ribosomal 16S and COI mtDNA, for the presence of two mitochondrial genomes in Perumytilus purpuratus. This may be considered evidence of doubly uniparental mtDNA inheritance. The presence of the two types of mitochondrial genomes differentiates females from males. The F...

journal_title：Genetics and molecular biology

authors： Vargas J,Pérez M,Toro J,Astorga MP

更新日期：2015-05-01 00:00:00

abstract：:Phylogenetic niche conservatism can be investigated at multiple scales on an explicit geographical context. Haplotype-based comparative analyses of lineages occupying the same region, and thus subjected to similar environmental factors, allow decoupling shared evolutionary and ecological patterns, as well as multiple ...

journal_title：Genetics and molecular biology

authors： Barros MJF,Silva-Arias GA,Segatto ALA,Reck-Kortmann M,Fregonezi JN,Diniz-Filho JAF,Freitas LB

更新日期：2020-04-27 00:00:00

abstract：:Several phylogeographic studies of seabirds have documented low genetic diversity that has been attributed to bottleneck events or individual capacity for dispersal. Few studies have been done in seabirds on the Brazilian coast and all have shown low genetic differentiation on a wide geographic scale. The Kelp Gull is...

journal_title：Genetics and molecular biology

authors： de Mendonça Dantas GP,Meyer D,Godinho R,Ferrand N,Morgante JS

更新日期：2012-12-01 00:00:00

abstract：:The applicability of mitochondrial nad6 sequences to studies of DNA and population variability in Lepidoptera was tested in four species of economically important moths and one of wild butterflies. The genetic information so obtained was compared to that of cox1 sequences for two species of Lepidoptera. nad6 primers a...

journal_title：Genetics and molecular biology

authors： Silva-Brandão KL,Lyra ML,Santos TV,Seraphim N,Albernaz KC,Pavinato VA,Martinelli S,Cônsoli FL,Omoto C

更新日期：2011-10-01 00:00:00

abstract：:The allelic frequencies of 12 short tandem repeat loci were obtained from a sample of 307 unrelated individuals living in Macapá, a city in the northern Amazon region, Brazil. These loci are the most commonly used in forensics and paternity testing. Based on the allele frequency obtained for the population of Macapá, ...

journal_title：Genetics and molecular biology

authors： da Costa Francez PA,Rodrigues EM,Frazão GF,Dos Reis Borges ND,Dos Santos SE

更新日期：2011-01-01 00:00:00

abstract：:The usefulness of IRAP (inter-retrotransposon amplified polymorphism) and ITS-RFLP (restriction of PCR-amplified internal transcribed spacers of the rDNA) markers in the analysis of 39 Pyrenophora graminea isolates was determined. Each marker system could discriminate between all of the isolates in detecting polymorph...

journal_title：Genetics and molecular biology

authors： Zein I,Jawhar M,Arabi MI

更新日期：2010-04-01 00:00:00

abstract：:Topoisomerase II inhibitors are effective chemotherapeutic agents in the treatment of cancer, in spite of being associated with the development of secondary leukemia. Our purpose was to determine the effects of etoposide on different genomic regions, aiming at discovering whether there are preferential sites which can...

journal_title：Genetics and molecular biology

authors： Brassesco MS,Montaldi AP,Sakamoto-Hojo ET

更新日期：2009-01-01 00:00:00

abstract：:The arylamine N-acetyltransferase 2 (NAT2) enzymes detoxify a wide range of naturally occurring xenobiotics including carcinogens and drugs. Point mutations in the NAT2 gene result in the variant alleles M1 (NAT2 *5A), M2 (NAT2*6A), M3 (NAT2*7) and M4 (NAT2 *14A) from the wild-type WT (NAT2 *4) allele. The current stu...

journal_title：Genetics and molecular biology

authors： Mahasneh A,Jubaili A,El Bateiha A,Al-Ghazo M,Matalka I,Malkawi M

更新日期：2012-12-01 00:00:00

abstract：:Blood methylated cell-free DNA (cfDNA) as a minimally invasive cancer biomarker has great importance in cancer management. Guanylate binding protein 2 (GBP2) has been considered as a possible controlling factor in tumor development. GBP2 gene expression and its promoter methylation status in both plasma cfDNA and tumo...

journal_title：Genetics and molecular biology

authors： Rahvar F,Salimi M,Mozdarani H

更新日期：2020-11-17 00:00:00

abstract：:Ample evidence suggests that cancer is triggered by mutagenic damage and diets or supplements capable of reducing such incidences can be related to the prevention of neoplasy development or to an improvement in life quality of patients who undergo chemotherapy. This research aimed to evaluate the antimutagenic and ant...

journal_title：Genetics and molecular biology

authors： Oliveira RJ,Salles MJ,da Silva AF,Kanno TY,Lourenço AC,Leite Vda S,Matiazi HJ,Pesarini JR,Ribeiro LR,Mantovani MS

更新日期：2013-09-01 00:00:00

abstract：:Lupinus albescens is a resistant cover plant that establishes symbiotic relationships with bacteria belonging to the Bradyrhizobium genus. This symbiosis helps the development of these plants in adverse environmental conditions, such as the ones found in arenized areas of Southern Brazil. This work studied three Brady...

journal_title：Genetics and molecular biology

authors： Granada CE,Vargas LK,Sant'Anna FH,Balsanelli E,Baura VA,Oliveira Pedrosa F,Souza EM,Falcon T,Passaglia LMP

更新日期：2018-04-01 00:00:00

abstract：:Exercise is a double-edged sword: when practiced in moderation, it increases the expression of antioxidant enzymes, but when practiced strenuously it causes oxidative stress and cell damage. In this context, polymorphisms in the interleukin (IL)-6 gene should be investigated better because they can influence performan...

journal_title：Genetics and molecular biology

authors： Miranda-Vilela AL,Ribeiro IF,Grisolia CK

更新日期：2016-10-01 00:00:00

abstract：:The Latin American School of Human and Medical Genetics (ELAG) is the main course of its kind in the genetics field in Latin America. Here we describe the main challenges regarding the organization of such event, including how we obtain funding and how we proceed with student selection. Thus, we aim to share our exper...

journal_title：Genetics and molecular biology

authors： Vairo F,López ML,Cruz CU,Corrêa PG,Baldo G

更新日期：2014-03-01 00:00:00

abstract：:Sample preparation is a critical step in two-dimensional gel electrophoresis (2-DE) of plant tissues. Here we describe a phenol/SDS procedure that, although greatly simplified, produced well-resolved and reproducible 2-DE profiles of protein extracts from soybean [Glycine max (L.) Merril] roots. Extractions were made ...

journal_title：Genetics and molecular biology

authors： Rodrigues EP,Torres AR,da Silva Batista JS,Huergo L,Hungria M

更新日期：2012-06-01 00:00:00