Abstract：
:In a myriad of engineering situations, we often hope to establish a model which can acquire load conditions around structures through flow features detection. A data-driven method is developed to predict the pressure on a cylinder from velocity distributions in its wake flow. The proposed deep learning neural network is constituted with convolutional layers and fully-connected layers: The convolutional layers can process the velocity information by features extraction, which are gathered by the fully-connected layers to obtain the pressure coefficients. By comparing the output data of the typical network with Computational Fluid Dynamics (CFD) results as reference values, it suggests that the present convolutional neural network (CNN) is able to predict the pressure coefficient in the vicinity of the trained Reynolds numbers with various inlet flow profiles and achieves a high overall precision. Moreover, a transfer learning approach is adopted to preserve the feature detection ability by keeping the parameters in the convolutional layers unchanged while shifting parameters in the fully-connected layers. Further results show that this transfer learning network has nearly the same precision while significantly lower cost. The active prospects of convolutional neural network in fluid mechanics have also been demonstrated, which can inspire more kinds of loads prediction in the future.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Ye S,Zhang Z,Song X,Wang Y,Chen Y,Huang Cdoi
10.1038/s41598-020-61450-zsubject
Has Abstractpub_date
2020-03-10 00:00:00pages
4459issue
1issn
2045-2322pii
10.1038/s41598-020-61450-zjournal_volume
10pub_type
杂志文章abstract：:Feedback information is essential for us to adapt appropriately to the environment. The feedback-related negativity (FRN), a frontocentral negative deflection after the delivery of feedback, has been found to be larger for outcomes that are worse than expected, and it reflects a reward prediction error derived from th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34032
更新日期：2016-10-03 00:00:00
abstract：:Electrospinning can be used to mimic the architecture of an acellular nerve graft, combining microfibers for guidance, and pores for cellular infiltration. We made electrospun nerve guides, from polycaprolactone (PCL) or poly-L-lactic acid (PLLA), with aligned fibers along the insides of the channels and random fibers...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34699-8
更新日期：2018-11-13 00:00:00
abstract：:Successful synthetic biology efforts rely on conceptual and experimental designs in combination with testing of multi-gene constructs. Despite recent progresses, several limitations still hinder the ability to flexibly assemble and collectively share different types of DNA segments. Here, we describe an advanced syste...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19278
更新日期：2016-01-13 00:00:00
abstract：:When acoustic signals from different sound sources are mixed upon arrival at the ears, the auditory system organizes these acoustic elements by their features. This study shows that individuals with autism spectrum disorder (ASD) performed better in terms of hearing a target sequence among distractors that had similar...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10524
更新日期：2015-05-22 00:00:00
abstract：:Plant seed germination is a crucial developmental event that has significant effects on seedling establishment and yield production. This process is controlled by multiple intrinsic signals, particularly phytohormones. The gaseous hormone ethylene stimulates seed germination; however, the genetic basis of ethylene pro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58607-1
更新日期：2020-02-03 00:00:00
abstract：:Medication-related osteonecrosis of the jaw (MRONJ) represents a complication of bisphosphonate treatment that responds poorly to standard treatment. In a retrospective cohort study we investigated a possible role of Actinomyces spp. in the pathogenesis of MRONJ. Deep biopsies of necrotic bone were collected during su...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31604
更新日期：2016-08-17 00:00:00
abstract：:Diabetes is caused by the loss or dysfunction of insulin-secreting β-cells in the pancreas. β-cells reduce their mass and lose insulin-producing ability in vitro, likely due to insufficient cell-cell and cell-extracellular matrix (ECM) interactions as β-cells lose their native microenvironment. Herein, we built an ex-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02863
更新日期：2013-10-04 00:00:00
abstract：:Recently, a genome-wide analysis identified DNA methylation of the HIF3A (hypoxia-inducible factor 3A) as strongest correlate of BMI. Here we tested the hypothesis that HIF3A mRNA expression and CpG-sites methylation in adipose tissue (AT) and genetic variants in HIF3A are related to parameters of AT distribution and ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27969
更新日期：2016-06-27 00:00:00
abstract：:We use satellite gravity measurements in the Gravity Recovery and Climate Experiment (GRACE) to estimate terrestrial water storage (TWS) change in the continental United States (US) from 2003 to 2012, and establish a GRACE-based Hydrological Drought Index (GHDI) for drought monitoring. GRACE-inferred TWS exhibits oppo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19909
更新日期：2016-01-27 00:00:00
abstract：:Superfluidity and superconductivity have been widely studied since the last century in many different contexts ranging from nuclear matter to atomic quantum gases. The rigidity of these systems with respect to external perturbations results in frictionless motion for superfluids and resistance-free electric current fl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08941-8
更新日期：2017-08-22 00:00:00
abstract：:In eusocial Hymenoptera (ants, bees and wasps), queen and worker adult castes typically arise via environmental influences. A fundamental challenge is to understand how a single genome can thereby produce alternative phenotypes. A powerful approach is to compare the molecular basis of caste determination and different...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45674
更新日期：2017-03-31 00:00:00
abstract：:Marine blue holes are precious geological heritages with high scientific research values. Their physical and chemical characteristics are unique because of the steep-walled structure and isolated water column which create isolated ecosystems in geographically restricted areas. The Sansha Yongle Blue Hole (SYBH) is the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67221-0
更新日期：2020-06-24 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep42494. ...
journal_title：Scientific reports
pub_type： 杂志文章,已发布勘误
doi：10.1038/srep46896
更新日期：2017-08-24 00:00:00
abstract：:Interleukin (IL) 16 plays a key role in inflammatory diseases as well as in tumorigenesis of osteosarcoma (OS). The aim of this study was to investigate the association of IL16 polymorphisms and plasma IL16 level with OS risk in a Chinese population. We genotyped IL16 rs4778889, rs11556218, and rs4072111 in 358 patien...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/srep34607
更新日期：2016-10-05 00:00:00
abstract：:The function of Forkhead box O 1 (FOXO1) and pSerine256-FOXO1 immunostaining in esophageal cancer is unclear. To clarify the prognostic role of nuclear FOXO1 and cytoplasmic pSerine256-FOXO1 immunostaining, a tissue microarray containing more than 600 esophageal cancers was analyzed. In non-neoplastic esophageal mucos...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35459-4
更新日期：2018-11-26 00:00:00
abstract：:Therapies using mesenchymal stem cell (MSC) seeded scaffolds may be applicable to various fields of regenerative medicine, including craniomaxillofacial surgery. Plastic compression of collagen scaffolds seeded with MSC has been shown to enhance the osteogenic differentiation of MSC as it increases the collagen fibril...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38814
更新日期：2016-12-09 00:00:00
abstract：:As a typical organic solid waste, sludge plays an important role in contributing to greenhouse gas (GHG) emissions resulted by its treatment and disposal. As a temporary and emergent treatment measurement, sludge lime stabilization is regionally adopted in most sludge generated units in China. In present case, sludge ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35052-9
更新日期：2018-11-08 00:00:00
abstract：:Cholinergic regulation of arterial luminal diameter involves intricate network of intercellular communication between the endothelial and smooth muscle cells that is highly dependent on the molecular mediators released by the endothelium. Albeit the well-recognized contribution of nitric oxide (NO) towards vasodilatio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20322
更新日期：2016-02-02 00:00:00
abstract：:Periodontitis is a local and systemic inflammatory condition and a risk factor of atherosclerosis, but no studies investigated the effect of a statin on atherogenesis affected by severe periodontitis. In this study, we investigated the effect of rosuvastatin (RSV) on atherogenesis in Apolipoprotein E-deficient mice re...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63350-8
更新日期：2020-04-14 00:00:00
abstract：:In this study, we prepared, characterized, and performed toxicity analyses of poly(ε-caprolactone) nanocapsules loaded with neem oil. Three formulations were prepared by the emulsion/solvent evaporation method. The nanocapsules showed a mean size distribution around 400 nm, with polydispersity below 0.2 and were stabl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06092-4
更新日期：2017-07-19 00:00:00
abstract：:The transforming growth factor beta (TGFβ) related signaling is one of the most important signaling pathways regulating early developmental events. Smad2 and Smad3 are structurally similar and it is mostly considered that they are equally important in mediating TGFβ signals. Here, we show that Smad3 is an insensitive ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21602
更新日期：2016-02-24 00:00:00
abstract：:Tissue adhesion is a common complication after surgery. In this work, a dexamethasone loaded polymeric micelles in thermosensitive hydrogel composite (Dex hydrogel) was prepared, which combined the anti-adhesion barrier with controlled release of anti-adhesion drug. Dexamethasone (Dex) was encapsulated in polymeric mi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13553
更新日期：2015-09-01 00:00:00
abstract：:The prevalence of chronic kidney disease (CKD), characterized by progressive renal dysfunction with tubulointerstitial fibrosis, is increasing because of societal aging. Uremic toxins, accumulated during renal dysfunction, cause kidney damage, leading to renal deterioration. A recent metabolomic analysis revealed that...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11049-8
更新日期：2017-09-11 00:00:00
abstract：:Extracorporeal membrane oxygenation (ECMO) is used for rescue in severe respiratory and/or circulatory failure. The patient's blood is pumped over artificial surfaces in the ECMO circuit. A platelet activation model was applied to study the potential thrombogenicity of ECMO circuit components: the centrifugal blood pu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32247-y
更新日期：2018-09-18 00:00:00
abstract：:We have proposed and successfully demonstrated a novel approach to direct conversion of mechanical energy into electrical energy using microfluidics. The method combines previously demonstrated reverse electrowetting on dielectric (REWOD) phenomenon with the fast self-oscillating process of bubble growth and collapse....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16537
更新日期：2015-11-16 00:00:00
abstract：:Identification of key regulators and regulatory pathways is an important step in the discovery of genes involved in cancer. Here, we propose a method to identify key regulators in prostate cancer (PCa) from a network constructed from gene expression datasets of PCa patients. Overexpressed genes were identified using B...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52896-x
更新日期：2019-11-11 00:00:00
abstract：:Neural connectivity requires neuronal differentiation, axon growth, and precise target innervation. Midbrain dopaminergic neurons project via the nigrostriatal pathway to the striatum to regulate voluntary movement. While the specification and differentiation of these neurons have been extensively studied, the molecul...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08900-3
更新日期：2017-08-17 00:00:00
abstract：:Endothelin-B receptor agonist, IRL-1620, provides significant neuroprotection following cerebral ischemia in rats. Whether this neuroprotection is due to inhibition of apoptosis is unknown. IRL-1620-treated rats following permanent middle cerebral artery occlusion (MCAO) showed significant improvement in neurological ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46203-x
更新日期：2019-07-18 00:00:00
abstract：:Current chemical markers based quality assessment methods largely fail to reflect intrinsic chemical complexity and multiple mechanisms of action of botanical drugs (BD). The development of novel quality markers is greatly needed. Here we propose bioactive chemical markers (BCM), defined as a group of chemo-markers th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02305-y
更新日期：2017-05-25 00:00:00
abstract：:We compared commercial kits for extraction of genomic DNA from the Gram-negative bacterium Klebsiella pneumoniae for subsequent Miseq sequencing. Purification of DNA was based on matrix binding (silica or anion exchange resin) or differential precipitation (salting out), respectively. The choice of extraction kit had ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28063
更新日期：2016-06-17 00:00:00
