An innovative platform for quick and flexible joining of assorted DNA fragments.

abstract：:Uterine carcinosarcomas (UCSs) are highly aggressive malignancies associated with poor prognoses and limited treatment options. These tumors are hypothesized to develop from the endometrial adenocarcinoma (EAC) through epithelial-mesenchymal transition (EMT). We test this long-standing hypothesis by depleting miR-200,...

journal_title：Scientific reports

authors： Tseng JH,Bisogna M,Hoang LN,Olvera N,Rodriguez-Aguayo C,Lopez-Berestein G,Sood AK,Levine DA,Jelinic P

更新日期：2017-06-15 00:00:00

abstract：:Ocean warming with climate change is forcing marine organisms to shift their distributions polewards and phenology. In warm tropical seas, evolutionary adaptation by local species to warming will be crucial to avoid predicted desertification and reduction in diversity. However, little is known about the adaptation of ...

journal_title：Scientific reports

authors： Jin P,Agustí S

更新日期：2018-12-11 00:00:00

abstract：:Plasmodiophora brassicae causes clubroot, a major disease of Brassica oil and vegetable crops worldwide. P. brassicae is a Plasmodiophorid, obligate biotrophic protist in the eukaryotic kingdom of Rhizaria. Here we present the 25.5 Mb genome draft of P. brassicae, developmental stage-specific transcriptomes and a tran...

journal_title：Scientific reports

authors： Schwelm A,Fogelqvist J,Knaust A,Jülke S,Lilja T,Bonilla-Rosso G,Karlsson M,Shevchenko A,Dhandapani V,Choi SR,Kim HG,Park JY,Lim YP,Ludwig-Müller J,Dixelius C

更新日期：2015-06-18 00:00:00

abstract：:Spin fluctuations are widely believed to play an important role in the superconducting mechanisms of unconventional high temperature superconductors. Spin fluctuations have been observed in iron-based superconductors as well. However, in some iron-based superconductors such as LaFePO0.9, they have not been observed by...

journal_title：Scientific reports

authors： Ishikado M,Shamoto SI,Kodama K,Kajimoto R,Nakamura M,Hong T,Mutka H

更新日期：2018-11-05 00:00:00

abstract：:Portal vein ligation (PVL) induces atrophy/hypertrophy complex (AHC). We hypothesised that simultaneous bile duct and portal vein ligation (BPL) might induce proper bile acid (BA) retention to enhance AHC by activating BA-mediated FXR signalling in the intact liver and promoting apoptosis in the ligated liver. We esta...

journal_title：Scientific reports

authors： Ren W,Chen G,Wang X,Zhang A,Li C,Lv W,Pan K,Dong JH

更新日期：2015-02-13 00:00:00

abstract：:The networks of predator-prey interactions in ecological systems are remarkably complex, but nevertheless surprisingly stable in terms of long term persistence of the system as a whole. In order to understand the mechanism driving the complexity and stability of such food webs, we developed an eco-evolutionary model i...

journal_title：Scientific reports

authors： Allhoff KT,Ritterskamp D,Rall BC,Drossel B,Guill C

更新日期：2015-06-04 00:00:00

abstract：:The Klein tunneling of optical waves near the Dirac points in the metal-dielectric multilayer metamaterials is theoretically investigated and demonstrated through the coupled-mode theory under the tight-binding approximation and the rigorous band structure analysis based on the transfer-matrix method. The optical anal...

journal_title：Scientific reports

authors： Sun L,Gao J,Yang X

更新日期：2017-08-29 00:00:00

abstract：:Insects have evolved multiple mechanisms to adapt to variations in environmental temperatures, including postural control of solar input, variations in diurnal activity, external morphological structures and selecting/generating microhabitats. Foam produced by Mahanarva fimbriolata nymphs (also known as root spittlebu...

journal_title：Scientific reports

authors： Tonelli M,Gomes G,Silva WD,Magri NTC,Vieira DM,Aguiar CL,Bento JMS

更新日期：2018-03-16 00:00:00

abstract：:We have performed a genome-wide association study (GWAS) including 473 Japanese HBV (hepatitis B virus)-positive HCC (hepatocellular carcinoma) patients and 516 HBV carriers including chronic hepatitis and asymptomatic carrier individuals to identify new host genetic factors associated with HBV-derived HCC in Japanese...

journal_title：Scientific reports

authors： Sawai H,Nishida N,Khor SS,Honda M,Sugiyama M,Baba N,Yamada K,Sawada N,Tsugane S,Koike K,Kondo Y,Yatsuhashi H,Nagaoka S,Taketomi A,Fukai M,Kurosaki M,Izumi N,Kang JH,Murata K,Hino K,Nishina S,Matsumoto A,Tanaka

更新日期：2018-05-21 00:00:00

abstract：:We propose two generalized Haldane models on laser-coupling optical lattices. Laser-assisted nearest neighbour tunnelings generate artificial staggered magnetic flux, facilitating the realization of topological nontrivial band structures. As generalizations of Haldane model, these models support topological insulator ...

journal_title：Scientific reports

authors： Liu W,Lin Z,Wang ZD,Chen Y

更新日期：2018-08-27 00:00:00

abstract：UNLABELLED:Understanding the mechanism of the strain-dependent conductivity change in polymers in stretched conditions is important. We observed a strain-induced growth of the conductive regions of PEDOT:PSS films, induced by a coalescence of conductive PEDOT-rich cores. This growth due to coalescence leads to a gradu...

journal_title：Scientific reports

authors： Lee YY,Choi GM,Lim SM,Cho JY,Choi IS,Nam KT,Joo YC

更新日期：2016-04-29 00:00:00

abstract：:Tobacco smoking is the major cause of many chronic diseases, especially lung cancer. Knowledge about population-wide tobacco use and exposure is essential to characterise its burden on public health and evaluate policy efficacy. Obtaining such knowledge remains challenging with current methods (e.g., surveys, biomonit...

journal_title：Scientific reports

authors： Lai FY,Lympousi K,Been F,Benaglia L,Udrisard R,Delémont O,Esseiva P,Thomaidis NS,Covaci A,van Nuijs ALN

更新日期：2018-09-05 00:00:00

abstract：:Priming improves an organism's performance upon a future stress. To test whether cold priming supports protection in spring and how it is affected by cold acclimation, we compared seven Arabidopsis accessions with different cold acclimation potentials in the field and in the greenhouse for growth, photosynthetic perfo...

journal_title：Scientific reports

authors： Cvetkovic J,Müller K,Baier M

更新日期：2017-03-09 00:00:00

abstract：:Geriatric trauma is a major socio-economic problem, especially among the aging Japanese society. Geriatric people are more vulnerable to trauma than younger people; thus, their outcomes are often severe. This study evaluates the characteristics of geriatric trauma divided by age in the Japanese population. We evaluate...

journal_title：Scientific reports

authors： Miyoshi Y,Kondo Y,Hirano Y,Ishihara T,Sueyoshi K,Okamoto K,Tanaka H

更新日期：2020-11-05 00:00:00

abstract：:A novel polyphenolic natural product, galewone, with undescribed carbon skeleton, was isolated as a racemate from the culture of Daldinia eschscholzii IFB-TL01, a fungus obtained from the mantis (Tenodera aridifolia) gut. The galewone structure was elucidated by a combination of MS and NMR spectra, and substantiated b...

journal_title：Scientific reports

authors： Zhang AH,Jiang N,Wang XQ,Tan RX

更新日期：2019-10-04 00:00:00

abstract：:Carcinoembryonic antigen (CEA) is the only blood based protein biomarker at present, used for preoperative screening of advanced colorectal cancer (CRC) patients to determine the appropriate curative treatments and post-surveillance screening for tumour recurrence. Current diagnostics for CRC detection have several li...

journal_title：Scientific reports

authors： Shamsuddin SH,Jayne DG,Tomlinson DC,McPherson MJ,Millner PA

更新日期：2021-01-12 00:00:00

abstract：:Spiny mice of the genus Acomys display several unique physiological traits, including menstruation and scar-free wound healing; characteristics that are exceedingly rare in mammals, and of considerable interest to the scientific community. These unique attributes, and the potential for spiny mice to accurately model h...

journal_title：Scientific reports

authors： Mamrot J,Legaie R,Ellery SJ,Wilson T,Seemann T,Powell DR,Gardner DK,Walker DW,Temple-Smith P,Papenfuss AT,Dickinson H

更新日期：2017-08-21 00:00:00

abstract：:Few studies focused on the residue of thiamethoxam and its metabolite clothianidin on strawberry where it is widely used, despite this is essential to assess the potential food risk of thiamethoxam and its main metabolite clothianidin. In this study, the dissipation of thiamethoxam and its metabolite clothianidin duri...

journal_title：Scientific reports

authors： Liu N,Pan X,Yang Q,Ji M,Zhang Z

更新日期：2018-10-15 00:00:00

abstract：:It is well known that collective migrations of oxygen vacancies in oxide is the key principle of resistance change in oxide-based resistive memory (OxRAM). The practical usefulness of OxRAM mainly arises from the fact that these oxygen vacancy migrations take place at relatively low operating voltages. The activation ...

journal_title：Scientific reports

authors： Hur JH

更新日期：2019-11-19 00:00:00

abstract：:The Arabidopsis Tóxicos en Levadura (ATL) protein family is a class of E3 ubiquitin ligases with a characteristic RING-H2 Zn-finger structure that mediates diverse physiological processes and stress responses in plants. We carried out a genome-wide survey of grapevine (Vitis vinifera L.) ATL genes and retrieved 96 seq...

journal_title：Scientific reports

authors： Ariani P,Regaiolo A,Lovato A,Giorgetti A,Porceddu A,Camiolo S,Wong D,Castellarin S,Vandelle E,Polverari A

更新日期：2016-12-02 00:00:00

abstract：:Because of inadequate nutrient and water supply, soils are often unproductive in Northwest China. We studied the effects of manure application at low (LM 7.5  t ha(-1)), medium (MM 15 t ha(-1)), and high (HM 22.5 t ha(-1)) rates combined with fixed levels of chemical fertilizers on maize growth and rainfall use effici...

journal_title：Scientific reports

authors： Wang X,Jia Z,Liang L,Yang B,Ding R,Nie J,Wang J

更新日期：2016-02-12 00:00:00

abstract：:This study aimed to detect the spatial distribution and high-risk clusters of female breast cancer mortality for the years 2011 to 2013 in Shandong Province, China. The urban-rural difference in the spatial distribution and clusters of disease mortality were also examined. Breast cancer mortality data were obtained fr...

journal_title：Scientific reports

authors： Chu J,Zhou C,Guo X,Sun J,Xue F,Zhang J,Lu Z,Fu Z,Xu A

更新日期：2017-03-07 00:00:00

abstract：:Functional interplays of microbial activity, genetic diversity and contaminant transformation are poorly understood in reactors for mineralizing halogenated aromatics anaerobically. Here, we investigated abundance and distribution of potential microbes and functional genes associated with pentachlorophenol (PCP) anaer...

journal_title：Scientific reports

authors： Li ZL,Nan J,Huang C,Liang B,Liu WZ,Cheng HY,Zhang C,Zhang D,Kong D,Kanamaru K,Kobayashi T,Wang AJ,Katayama A

更新日期：2016-01-11 00:00:00

abstract：:Si holds great promise as an alloying anode material for Li-ion batteries with improved energy density because of its high theoretical specific capacity and favorable operation voltage range. However, the large volume expansion of Si during electrochemical reaction with Li and the associated adverse effects strongly l...

journal_title：Scientific reports

authors： Breitung B,Aguiló-Aguayo N,Bechtold T,Hahn H,Janek J,Brezesinski T

更新日期：2017-10-12 00:00:00

abstract：:Kluyveromyces marxianus, a non-conventional thermotolerant yeast, is potentially useful for production of ethanol and other products. This species has a strong tendency to randomly integrate transforming DNA fragments, making necessary the development of more precise methods for gene targeting. In this study, we first...

journal_title：Scientific reports

authors： Nambu-Nishida Y,Nishida K,Hasunuma T,Kondo A

更新日期：2017-08-21 00:00:00

abstract：:Colorectal cancer is one of the main causes of cancer death worldwide, and novel biomarkers are urgently needed for its early diagnosis and treatment. The utilization of metabolomics to identify and quantify metabolites in body fluids may allow the detection of changes in their concentrations that could serve as diagn...

journal_title：Scientific reports

authors： Martín-Blázquez A,Díaz C,González-Flores E,Franco-Rivas D,Jiménez-Luna C,Melguizo C,Prados J,Genilloud O,Vicente F,Caba O,Pérez Del Palacio J

更新日期：2019-12-27 00:00:00

abstract：:Predation has driven the evolution of diverse adaptations for defence among prey, and one striking example is the deimatic display. While such displays can resemble, or indeed co-occur with, aposematic 'warning' signals, theory suggests deimatic displays may function independently of predator learning. The survival va...

journal_title：Scientific reports

authors： Umbers KDL,White TE,De Bona S,Haff T,Ryeland J,Drinkwater E,Mappes J

更新日期：2019-01-24 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Robertson KE,Truong CD,Craciunescu FM,Yang JH,Chiu PL,Fromme P,Hansen DT

更新日期：2020-03-02 00:00:00

abstract：:Traditional radiomics models mainly rely on explicitly-designed handcrafted features from medical images. This paper aimed to investigate if deep features extracted via transfer learning can generate radiomics signatures for prediction of overall survival (OS) in patients with Glioblastoma Multiforme (GBM). This study...

journal_title：Scientific reports

authors： Lao J,Chen Y,Li ZC,Li Q,Zhang J,Liu J,Zhai G

更新日期：2017-09-04 00:00:00

abstract：:Hexagonal Fe(3)Sn has many of the desirable properties for a new permanent magnet phase with a Curie temperature of 725 K, a saturation moment of 1.18 MA/m. and anisotropy energy, K1 of 1.8 MJ/m(3). However, contrary to earlier experimental reports, we found both experimentally and theoretically that the easy magnetic...

journal_title：Scientific reports

authors： Sales BC,Saparov B,McGuire MA,Singh DJ,Parker DS

更新日期：2014-11-12 00:00:00