De novo transcriptome assembly for the spiny mouse (Acomys cahirinus).

abstract：:The ability to inhibit previously employed strategies and flexibly adjust behavioural responses to external conditions may be critical for individual survival. However, it is unclear which factors predict their distribution across species. Here, we investigated social inhibition and behavioural flexibility in six prim...

journal_title：Scientific reports

authors： Amici F,Call J,Watzek J,Brosnan S,Aureli F

更新日期：2018-02-15 00:00:00

abstract：:Hepatocellular carcinoma is a common type of malignancy with a poor prognosis. Identification and utilisation of markers for monitoring and diagnosis are urgently needed. Alpha-fetoprotein (AFP) and Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) have been proved to be efficient biomarkers for hepatit...

journal_title：Scientific reports

authors： Wang G,Lu X,Du Q,Zhang G,Wang D,Wang Q,Guo X

更新日期：2020-08-11 00:00:00

abstract：:Regulatory T cells (Tregs) expand in peripheral lymphoid organs and can produce immunosuppressive cytokines to support tumor growth. IL-10 abrogation efficiently induces Treg formation but dampens tumoral neuropilin-1 (Nrp-1) Treg signaling, which simultaneously augments Th1 and Th17 immunity. These effects are associ...

journal_title：Scientific reports

authors： Wang S,Gao X,Shen G,Wang W,Li J,Zhao J,Wei YQ,Edwards CK

更新日期：2016-04-14 00:00:00

abstract：:Sodium taurocholate cotransporting polypeptide (NTCP) is a recently discovered hepatitis B virus (HBV) receptor. In the present study, we used TK-NOG mice with a humanized liver to examine the impact of endogenous NTCP expression on HBV infection. Upon inoculation with HBV, these mice exhibited clear viremia in 2 week...

journal_title：Scientific reports

authors： Nakabori T,Hikita H,Murai K,Nozaki Y,Kai Y,Makino Y,Saito Y,Tanaka S,Wada H,Eguchi H,Takahashi T,Suemizu H,Sakamori R,Hiramatsu N,Tatsumi T,Takehara T

更新日期：2016-06-09 00:00:00

abstract：:Non-response to intravitreal ranibizumab represents a frequent problem in pachychoroid neovasculopathy (PNV). To investigate the effectivity of switching to aflibercept, the database of the Ludwig Maximilians University, Munich, was screened for patients fulfilling the following inclusion criteria: (i) diagnosis of PN...

journal_title：Scientific reports

authors： Schworm B,Luft N,Keidel LF,Herold TR,Wolf A,Priglinger SG,Siedlecki J

更新日期：2020-05-21 00:00:00

abstract：:The tibial tuberosity-trochlear groove (TT-TG) distance is a radiographic measurement that is used to quantify malalignment of the patellofemoral joint (PFJ) in cross-sectional imaging. There is an ongoing debate about the impact of the TT-TG-distance on lateral patellar instability and the initiating of cartilage deg...

journal_title：Scientific reports

authors： Maas KJ,Warncke M,Behzadi C,Welsch GH,Schoen G,Kaul MG,Adam G,Bannas P,Henes FO

更新日期：2020-09-18 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are highly plastic cells that are able to transdifferentiate or dedifferentiate under appropriate conditions. In the present study, we reported here that after in vitro induction of osteogenic differentiation, MSCs could be reverted to a primitive stem cell population (dedifferentiated os...

journal_title：Scientific reports

authors： Rui Y,Xu L,Chen R,Zhang T,Lin S,Hou Y,Liu Y,Meng F,Liu Z,Ni M,Tsang KS,Yang F,Wang C,Chan HC,Jiang X,Li G

更新日期：2015-06-08 00:00:00

abstract：:The objective of this study was to examine the relationship between sleep duration and ischemic and hemorrhagic stroke in a community-based cohort. The current analysis included 95,023 Chinese participants who were free of stroke at the baseline survey (2006-2007). Cox proportional hazards models were used to calculat...

journal_title：Scientific reports

authors： Song Q,Liu X,Zhou W,Wang L,Zheng X,Wang X,Wu S

更新日期：2016-09-16 00:00:00

abstract：:Mitochondria are key cellular signaling platforms, affecting fundamental processes such as cell proliferation, differentiation and death. However, it remains unclear how mitochondrial signaling affects other organelles, particularly lysosomes. Here, we demonstrate that mitochondrial respiratory chain (RC) impairments ...

journal_title：Scientific reports

authors： Fernández-Mosquera L,Diogo CV,Yambire KF,Santos GL,Luna Sánchez M,Bénit P,Rustin P,Lopez LC,Milosevic I,Raimundo N

更新日期：2017-03-27 00:00:00

abstract：:Secondary bacterial infections increase morbidity and mortality of influenza A virus (IAV) infections. Bacteria are able to invade due to virus-induced depletion of alveolar macrophages (AMs), but this is not the only contributing factor. By analyzing a kinetic model, we uncovered a nonlinear initial dose threshold th...

journal_title：Scientific reports

authors： Smith AM,Smith AP

更新日期：2016-12-15 00:00:00

abstract：:Amine quantification is an important strategy in patient stratification and personalised medicine. This is because amines, including amino acids and methylarginines impact on many homeostatic processes. One important pathway regulated by amine levels is nitric oxide synthase (NOS). NOS is regulated by levels of (i) th...

journal_title：Scientific reports

authors： Ahmetaj-Shala B,Olanipekun M,Tesfai A,MacCallum N,Kirkby NS,Quinlan GJ,Shih CC,Kawai R,Mumby S,Paul-Clark M,Want EJ,Mitchell JA

更新日期：2018-09-18 00:00:00

abstract：:Carbon nanofibers were widely utilized to improve microwave absorption properties since they are a promising lightweight candidate. Adjustable conductive nanostructures of carbon nanofibers were synthesized by electrospinning technique. The conductive network is controlled by the polyvinyl pyrrolidone (PVP) content du...

journal_title：Scientific reports

authors： Lv J,Gu W,Cui X,Dai S,Zhang B,Ji G

更新日期：2019-03-12 00:00:00

abstract：:The precision prediction of peptide retention time (RT) plays an increasingly important role in liquid chromatography-tandem mass spectrometry (LC-MS/MS) based proteomics. Owing to the high reproducibility of liquid chromatography, RT prediction provides promising information for both identification and quantification...

journal_title：Scientific reports

authors： Lu W,Liu X,Liu S,Cao W,Zhang Y,Yang P

更新日期：2017-03-17 00:00:00

abstract：:Plastic pollution is a rapidly worsening environmental problem, especially in oceanic habitats. Environmental pollution with microplastic particles is also causing food consumed by humans to be increasingly polluted, including table salts. Therefore, we present the first study which focuses only on table salt products...

journal_title：Scientific reports

authors： Lee H,Kunz A,Shim WJ,Walther BA

更新日期：2019-07-12 00:00:00

abstract：:Mechanistic disease progression studies using animal models require objective and quantifiable assessment of tissue pathology. Currently quantification relies heavily on staining methods which can be expensive, labor/time-intensive, inconsistent across laboratories and batch, and produce uneven staining that is prone ...

journal_title：Scientific reports

authors： Ternes L,Huang G,Lanciault C,Thibault G,Riggers R,Gray JW,Muschler J,Chang YH

更新日期：2020-12-01 00:00:00

abstract：:The innovation of iconic gestures is essential to establishing the vocabularies of signed languages, but might iconicity also play a role in the origin of spoken words? Can people create novel vocalizations that are comprehensible to naïve listeners without prior convention? We launched a contest in which participants...

journal_title：Scientific reports

authors： Perlman M,Lupyan G

更新日期：2018-02-08 00:00:00

abstract：:An enormous amount of tumor sequencing data has been generated through large scale sequencing efforts. The functional consequences of the majority of mutations identified by such projects remain an open, unexplored question. This problem is particularly complicated in the case of rare mutations where frequency of occu...

journal_title：Scientific reports

authors： Katigbak A,Cencic R,Robert F,Sénécha P,Scuoppo C,Pelletier J

更新日期：2016-12-16 00:00:00

abstract：:Obesity is associated with substantial morbidity, costs, and decreased life expectancy, and continues to rise worldwide. While etiological understanding is needed for prevention, epidemiological studies indicated that colonization with Helicobacter pylori (H. pylori) may affect body mass index (BMI), but with inconsis...

journal_title：Scientific reports

authors： den Hollander WJ,Broer L,Schurmann C,Meyre D,den Hoed CM,Mayerle J,Hofman A,Homuth G,Uitterlinden AG,Lerch MM,Kuipers EJ

更新日期：2017-10-31 00:00:00

abstract：:The increasing ease and accuracy of protein-protein interaction detection has resulted in the ability to map the interactomes of multiple species. We now have an opportunity to compare species to better understand how interactomes evolve. As DNA and protein sequence alignment algorithms were required for comparative g...

journal_title：Scientific reports

authors： Law B,Bader GD

更新日期：2015-07-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： McGrath EC,Woods L,Jompa J,Haris A,Bell JJ

更新日期：2019-11-27 00:00:00

abstract：:During viral infections, some viruses subvert the host proteins to promote the translation or RNA replication with their protease-mediated cleavage. Poly (A)-binding protein (PABP) is a target for several RNA viruses; however, the impact of duck hepatitis A virus (DHAV) on PABP remains unknown. In this study, we demon...

journal_title：Scientific reports

authors： Sun D,Wang M,Wen X,Cheng A,Jia R,Sun K,Yang Q,Wu Y,Zhu D,Chen S,Liu M,Zhao X,Chen X

更新日期：2017-11-24 00:00:00

abstract：:Herein, we have fabricated rutile TiO2 nanorod-coupled α-Fe2O3 by a wet-chemical process. It is demonstrated that the visible activities for photoelectrochemical water oxidation and for degrading pollutant of α-Fe2O3 are greatly enhanced after coupling a proper amount of rutile nanorods. The enhanced activity is attri...

journal_title：Scientific reports

authors： Luan P,Xie M,Liu D,Fu X,Jing L

更新日期：2014-08-26 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is an increasing health problem worldwide, with genetic, epigenetic, and environmental components. Here, we describe the first example of NAFLD caused by genetic disruption of a mammalian potassium channel subunit. Mice with germline deletion of the KCNE2 potassium channel β su...

journal_title：Scientific reports

authors： Lee SM,Nguyen D,Anand M,Kant R,Köhncke C,Lisewski U,Roepke TK,Hu Z,Abbott GW

更新日期：2016-03-17 00:00:00

abstract：:We study an Ising chain undergoing a quantum phase transition in a quantum magnetic field. Such a field can be emulated by coupling the chain to a central spin initially in a superposition state. We show that--by adiabatically driving such a system--one can prepare a quantum superposition of any two ground states of t...

journal_title：Scientific reports

authors： Rams MM,Zwolak M,Damski B

更新日期：2012-01-01 00:00:00

abstract：:The poor control of the adhesion of TiO2 nanotubes (TNTs) layers to a non-anodized titanium (Ti) substrate has limited their widespread application, because the stripping mechanism has not yet been revealed. Here, we report a novel method to control the detachment of TNTs by post-treatment of the as-fabricated samples...

journal_title：Scientific reports

authors： Zhao M,Li J,Li Y,Wang J,Zuo Y,Jiang J,Wang H

更新日期：2014-11-24 00:00:00

abstract：:Bee-pollinated plants face a dilemma in that bees both passively transport pollen grains among conspecific flowers and actively collect pollen to feed their larvae. Therefore, mechanisms that reduce pollen collection by bees have evolved in melittophilous plants. Malvaceae pollen is uncollectable for corbiculate bees ...

journal_title：Scientific reports

authors： Konzmann S,Koethe S,Lunau K

更新日期：2019-03-18 00:00:00

abstract：:Tracking animal behavior by video is one of the most common tasks in the life sciences. Although commercial software exists for executing this task, they often present enormous cost to the researcher and can entail purchasing hardware that is expensive and lacks adaptability. Additionally, the underlying code is often...

journal_title：Scientific reports

authors： Pennington ZT,Dong Z,Feng Y,Vetere LM,Page-Harley L,Shuman T,Cai DJ

更新日期：2019-12-27 00:00:00

abstract：:Pediococcus pentosaceus LBM 18 has shown potential as producer of an antibacterial and antifungal bacteriocin-like inhibitory substance (BLIS). BLIS inhibited the growth of spoilage bacteria belonging to Lactobacillus, Enterococcus and Listeria genera with higher activity than Nisaplin used as control. It gave rise to...

journal_title：Scientific reports

authors： de Souza de Azevedo PO,Mendonça CMN,Moreno ACR,Bueno AVI,de Almeida SRY,Seibert L,Converti A,Watanabe IS,Gierus M,de Souza Oliveira RP

更新日期：2020-07-23 00:00:00

abstract：:Up to now, most of stimulated-emission-depletion (STED) systems were lens-based bulky systems. Exchanging some spatial light paths with optical fiber components will make the systems more flexible and will benefit various fields. A big problem to achieve this goal is that the STED beam generated by the traditional met...

journal_title：Scientific reports

authors： Luo H,Wang G,Yuan L

更新日期：2019-06-11 00:00:00

abstract：:Bismuth has long been a prototypical system for investigating phase transformations and melting at high pressure. Despite decades of experimental study, however, the lattice-level response of Bi to rapid (shock) compression and the relationship between structures occurring dynamically and those observed during slow (s...

journal_title：Scientific reports

authors： Gorman MG,Coleman AL,Briggs R,McWilliams RS,McGonegle D,Bolme CA,Gleason AE,Galtier E,Lee HJ,Granados E,Śliwa M,Sanloup C,Rothman S,Fratanduono DE,Smith RF,Collins GW,Eggert JH,Wark JS,McMahon MI

更新日期：2018-11-16 00:00:00