A special three-layer step-index fiber for building compact STED systems.

abstract：:Monanchoxymycalin C (MomC) is a new marine pentacyclic guanidine alkaloid, recently isolated from marine sponge Monanchora pulchra by us. Here, anticancer activity and mechanism of action was investigated for the first time using a human prostate cancer (PCa) model. MomC was active in all PCa cell lines at low micromo...

journal_title：Scientific reports

authors： Dyshlovoy SA,Kaune M,Kriegs M,Hauschild J,Busenbender T,Shubina LK,Makarieva TN,Hoffer K,Bokemeyer C,Graefen M,Stonik VA,von Amsberg G

更新日期：2020-08-06 00:00:00

abstract：:The common facets of anatase crystals are the (001) and (101) planes. However, the phase transformation from lepidocrocite-type titanate into anatase by hydrothermal processing yields an anatase microstructure with high concentration of exposed (010) planes. The phase transformation of a lepidocrocite-type protonated ...

journal_title：Scientific reports

authors： Yuan H,Besselink R,Liao Z,Ten Elshof JE

更新日期：2014-04-03 00:00:00

abstract：:Bovine tuberculosis (BTB) testing in cattle requires a significant investment of time, equipment, and labor. Novel, rapid, cheaper and accurate methods are needed. The Alere Determine TB lipoarabinomannan antigen (LAM-test) is a World Health Organization-endorsed point-of-care urine test designed to detect active TB d...

journal_title：Scientific reports

authors： Kelley HV,Waibel SM,Sidiki S,Tomatis-Souverbielle C,Scordo JM,Hunt WG,Barr N,Smith R,Silwani SN,Averill JJ,Baer S,Hengesbach J,Yildiz VO,Pan X,Gebreyes WA,Balada-Llasat JM,Wang SH,Torrelles JB

更新日期：2020-03-25 00:00:00

abstract：:Crosstalk between phytohormone pathways is essential in plant growth, development and stress responses. Brassinosteroids (BRs) and ethylene are both pivotal plant growth regulators, and the interaction between these two phytohormones in the tomato response to salt stress is still unclear. Here, we explored the mechani...

journal_title：Scientific reports

authors： Zhu T,Deng X,Zhou X,Zhu L,Zou L,Li P,Zhang D,Lin H

更新日期：2016-10-14 00:00:00

abstract：:Although large populations feel fatigue, the standardized medicinal therapy is currently absent. In this study, we determined whether 5-aminolevulinic acid (5-ALA) supplementation alleviates the feeling of fatigue in healthy subjects who feel chronic physical tiredness. Males and females between ages of 20 and 64 who ...

journal_title：Scientific reports

authors： Higashikawa F,Kanno K,Ogata A,Sugiyama M

更新日期：2020-09-29 00:00:00

abstract：:Currently, blueberry bruising is evaluated by either human visual/tactile inspection or firmness measurement instruments. These methods are destructive, time-consuming, and subjective. The goal of this paper was to develop a non-destructive approach for blueberry bruising detection and quantification. Experiments were...

journal_title：Scientific reports

authors： Jiang Y,Li C,Takeda F

更新日期：2016-10-21 00:00:00

abstract：:We describe a novel method to achieve a universal, massive, and fully automated analysis of cell motility behaviours, starting from time-lapse microscopy images. The approach was inspired by the recent successes in application of machine learning for style recognition in paintings and artistic style transfer. The orig...

journal_title：Scientific reports

authors： Mencattini A,Di Giuseppe D,Comes MC,Casti P,Corsi F,Bertani FR,Ghibelli L,Businaro L,Di Natale C,Parrini MC,Martinelli E

更新日期：2020-05-06 00:00:00

abstract：:Mouse embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs) represent naive and primed pluripotency states, respectively, and are maintained in vitro by specific signalling pathways. Furthermore, ESCs cultured in serum-free medium with two kinase inhibitors (2i-ESCs) are thought to be the ground naïve pluripote...

journal_title：Scientific reports

authors： Tosolini M,Brochard V,Adenot P,Chebrout M,Grillo G,Navia V,Beaujean N,Francastel C,Bonnet-Garnier A,Jouneau A

更新日期：2018-04-10 00:00:00

abstract：:Autism spectrum disorder (ASD) is marked by atypical trajectory of brain maturation, yet the developmental abnormalities in brain function remain unclear. The current study examined the effect of age on amplitude of low-frequency fluctuations (ALFF) in ASD and typical controls (TC) using a cross-sectional design. We c...

journal_title：Scientific reports

authors： Guo X,Chen H,Long Z,Duan X,Zhang Y,Chen H

更新日期：2017-01-06 00:00:00

abstract：:Herein, triphenyltin (TPT) biodegradation efficiency and its transformation pathway have been elucidated. To better understand the molecular mechanism of TPT degradation, the interactions between amino acids, primary structures, and quaternary conformations of effector proteins and TPT were studied. The results verifi...

journal_title：Scientific reports

authors： Wang L,Ye J,Ou H,Qin H,Long Y,Ke J

更新日期：2017-06-23 00:00:00

abstract：:Buccal mucosa squamous cell carcinoma (BMSCC) is one of major subsites of oral cancer and is associated with a high rate of metastasis and poor prognosis. Heat shock proteins (HSPs) act as potential prognostic biomarkers in many cancer types. However, the role of HSPD1 in oral cancer, especially in BMSCC, is still unk...

journal_title：Scientific reports

authors： Kang BH,Shu CW,Chao JK,Lee CH,Fu TY,Liou HH,Ger LP,Liu PF

更新日期：2019-06-20 00:00:00

abstract：:Many studies speak in favor of a rhythmic mode of listening, by which the encoding of acoustic information is structured by rhythmic neural processes at the time scale of about 1 to 4 Hz. Indeed, psychophysical data suggest that humans sample acoustic information in extended soundscapes not uniformly, but weigh the ev...

journal_title：Scientific reports

authors： Kubetschek C,Kayser C

更新日期：2021-01-27 00:00:00

abstract：:Almost half of the groundwater in the Pearl River Delta (PRD) contains salt water originally derived from paleo-seawater due to the Holocene transgression, which then generates intense physicochemical gradients in the mixing zone between freshwater and saltwater. Although some studies have been conducted on the hydrol...

journal_title：Scientific reports

authors： Sang S,Zhang X,Dai H,Hu BX,Ou H,Sun L

更新日期：2018-11-23 00:00:00

abstract：:There is lack of consensus regarding the prognostic significance of primary tumor location of upper tract urothelial carcinoma(UTUC). We performed a meta-analysis to evaluate the impact of primary tumor location on prognosis in patients with UTUC who had undergone radical nephroureterectomy(RNU). We included eligible ...

journal_title：Scientific reports

authors： Wu Y,Dong Q,Liu L,Han P,Wei Q

更新日期：2014-09-15 00:00:00

abstract：:Knowledge of the direct role humans have had in changing the landscape requires the perspective of historical and archaeological sources, as well as climatic and ecologic processes, when interpreting paleoecological records. People directly impact land at the local scale and land use decisions are strongly influenced ...

journal_title：Scientific reports

authors： Mensing SA,Schoolman EM,Tunno I,Noble PJ,Sagnotti L,Florindo F,Piovesan G

更新日期：2018-02-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) and cytokeratin 18 (CK18) were previously reported to be elevated in nonalcoholic fatty liver disease (NAFLD). We aim to analyze the differential roles of FGF21, cell apoptosis marker CK18 fragment M30 and total cell death marker CK18 M65ED in monitoring the different stages of NAFL...

journal_title：Scientific reports

authors： Wu G,Li H,Fang Q,Zhang J,Zhang M,Zhang L,Wu L,Hou X,Lu J,Bao Y,Jia W

更新日期：2017-07-11 00:00:00

abstract：:Acute heart failure (AHF) emerges either de novo or from worsening of chronic heart failure (CHF). The aim of the present study was to evaluate the association between worsening of CHF and mortality in AHF patients. Out of 152 included AHF patients, 47 (30.9%) were de novo AHF patients and 105 (69%) were AHF patients ...

journal_title：Scientific reports

authors： Degoricija V,Trbušić M,Potočnjak I,Radulović B,Terešak SD,Pregartner G,Berghold A,Tiran B,Frank S

更新日期：2018-06-25 00:00:00

abstract：:Features from Electrovestibulography (EVestG) recordings have been used to classify and measure the severity of both persistent post-concussion syndrome (PCS) and major depressive disorder. Herein, we examined the effect of comorbid depression on the detection of persistent PCS using EVestG. To validate our previously...

journal_title：Scientific reports

authors： Suleiman A,Lithgow B,Mansouri B,Moussavi Z

更新日期：2018-09-27 00:00:00

abstract：:Heparin is a widely used anticoagulant which inhibits factor Xa and thrombin through potentiation of antithrombin. We recently identified that the nucleic acid stain SYTOX reacts with platelet polyphosphate due to molecular similarities, some of which are shared by heparin. We attempted to study heparin in flowing blo...

journal_title：Scientific reports

authors： de Vries JC,Barendrecht AD,Clark CC,Urbanus RT,Boross P,de Maat S,Maas C

更新日期：2019-12-04 00:00:00

abstract：:Open-ended evolution (OEE) is relevant to a variety of biological, artificial and technological systems, but has been challenging to reproduce in silico. Most theoretical efforts focus on key aspects of open-ended evolution as it appears in biology. We recast the problem as a more general one in dynamical systems theo...

journal_title：Scientific reports

authors： Adams A,Zenil H,Davies PCW,Walker SI

更新日期：2017-04-20 00:00:00

abstract：:We describe a new species of an ornithischian dinosaur, Isaberrysaura mollensis gen. et sp. nov. The specimen, consisting in an almost complete skull and incomplete postcranium was collected from the marine-deltaic deposits of the Los Molles Formation (Toarcian-Bajocian), being the first reported dinosaur for this uni...

journal_title：Scientific reports

authors： Salgado L,Canudo JI,Garrido AC,Moreno-Azanza M,Martínez LC,Coria RA,Gasca JM

更新日期：2017-02-16 00:00:00

abstract：:Nitrification directly contributes to the ammonia removal in sponges, and it plays an indispensable role in sponge-mediated nitrogen cycle. Previous studies have demonstrated genomic evidences of nitrifying lineages in the sponge Theonella swinhoei. However, little is known about the transcriptional activity of nitrif...

journal_title：Scientific reports

authors： Feng G,Sun W,Zhang F,Karthik L,Li Z

更新日期：2016-04-26 00:00:00

abstract：:The theoretical optimal olfactory search strategy is to move cross-wind. Empirical evidence supporting wind-associated directionality among carnivores, however, is sparse. We examined satellite-linked telemetry movement data of adult female polar bears (Ursus maritimus) from Hudson Bay, Canada, in relation to modelled...

journal_title：Scientific reports

authors： Togunov RR,Derocher AE,Lunn NJ

更新日期：2017-04-12 00:00:00

abstract：:Visual loss caused by retinopathy of prematurity (ROP) will be prevented if treatment-requiring ROP (TR-ROP) can be predicted. In this retrospective study including 418 infants with ≤32 weeks of gestational age (GA) and/or ≤1500 grams of birthweight, we attempted to identify useful predictors. We also examined the eff...

journal_title：Scientific reports

authors： Arima M,Tsukamoto S,Fujiwara K,Murayama M,Fujikawa K,Sonoda KH

更新日期：2017-06-20 00:00:00

abstract：:Among the biologically active triterpenes, friedelin has the most-rearranged structure produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In this study, we cloned and functionally characterized friedelin synthase and one cycloartenol synthase from Maytenus ilicifolia (Celastraceae)....

journal_title：Scientific reports

authors： Souza-Moreira TM,Alves TB,Pinheiro KA,Felippe LG,De Lima GM,Watanabe TF,Barbosa CC,Santos VA,Lopes NP,Valentini SR,Guido RV,Furlan M,Zanelli CF

更新日期：2016-11-22 00:00:00

abstract：:Previous studies have documented that decompression led to endothelial dysfunction with controversial results. This study aimed to clarify the relationship between endothelial dysfunction, bubble formation and decompression rate. Rats were subjected to simulated air dives with one of four decompression rates: one slow...

journal_title：Scientific reports

authors： Zhang K,Wang D,Jiang Z,Ning X,Buzzacott P,Xu W

更新日期：2016-09-12 00:00:00

abstract：:Olanzapine is a second-generation antipsychotic (AP) drug commonly prescribed for the treatment of schizophrenia. Recently, olanzapine has been found to cause brain tissue volume loss in rodent and primate studies; however, the underlying mechanism remains unknown. Abnormal autophagy and oxidative stress have been imp...

journal_title：Scientific reports

authors： Boz Z,Hu M,Yu Y,Huang XF

更新日期：2020-11-05 00:00:00

abstract：:The neuronal accumulation of phosphorylated tau plays a critical role in the pathogenesis of Alzheimer's disease (AD). Here, we examined the effect of fisetin, a flavonol, on tau levels. Treatment of cortical cells or primary neurons with fisetin resulted in significant decreases in the levels of phosphorylated tau. I...

journal_title：Scientific reports

authors： Kim S,Choi KJ,Cho SJ,Yun SM,Jeon JP,Koh YH,Song J,Johnson GV,Jo C

更新日期：2016-04-26 00:00:00

abstract：:Given that observational associations may be inaccurate, we used offspring blood pressure (BP) to provide alternative estimates of the associations between own BP and mortality. Observational associations between BP and mortality, estimated as hazard ratios (HRs) from Cox regression, were compared to HRs obtained usin...

journal_title：Scientific reports

authors： Wade KH,Carslake D,Nilsen TI,Timpson NJ,Davey Smith G,Romundstad P

更新日期：2015-07-22 00:00:00

abstract：:Exploiting pattern formation - such as that observed in nature - in the context of micro/nanotechnology could have great benefits if coupled with the traditional top-down lithographic approach. Here, we demonstrate an original and simple method to produce unique, localized and controllable self-organised patterns on e...

journal_title：Scientific reports

authors： Seghir R,Arscott S

更新日期：2015-10-06 00:00:00