Complementary Role of Fibroblast Growth Factor 21 and Cytokeratin 18 in Monitoring the Different Stages of Nonalcoholic Fatty Liver Disease.

abstract：:Neuropsychological assessment of human visual processing capabilities strongly depends on visual testing conditions including room lighting, stimuli, and viewing-distance. This limits standardization, threatens reliability, and prevents the assessment of core visual functions such as visual processing speed. Increasin...

journal_title：Scientific reports

authors： Foerster RM,Poth CH,Behler C,Botsch M,Schneider WX

更新日期：2016-11-21 00:00:00

abstract：:New techniques for the field detection of inorganic improvised explosive devices (IEDs) are urgently developed. Although ion mobility spectrometry (IMS) has been proved to be the most effective method for screening organic explosives, it still faces a major challenge to detect inorganic explosives owing to their low v...

journal_title：Scientific reports

authors： Peng L,Hua L,Wang W,Zhou Q,Li H

更新日期：2014-10-16 00:00:00

abstract：:We have demonstrated a proof-of-principle experiment of reference-frame-independent phase coding quantum key distribution (RFI-QKD) over an 80-km optical fiber. After considering the finite-key bound, we still achieve a distance of 50 km. In this scenario, the phases of the basis states are related by a slowly time-va...

journal_title：Scientific reports

authors： Liang WY,Wang S,Li HW,Yin ZQ,Chen W,Yao Y,Huang JZ,Guo GC,Han ZF

更新日期：2014-01-09 00:00:00

abstract：:Cardiac progenitor cells (CPCs) have been shown to promote cardiac regeneration and improve heart function. However, evidence suggests that their regenerative capacity may be limited in conditions of severe hypoxia. Elucidating the mechanisms involved in CPC protection against hypoxic stress is essential to maximize t...

journal_title：Scientific reports

authors： Bellio MA,Pinto MT,Florea V,Barrios PA,Taylor CN,Brown AB,Lamondin C,Hare JM,Schulman IH,Rodrigues CO

更新日期：2017-08-29 00:00:00

abstract：:The vascular smooth muscle cells (VSMCs) are exposed to interstitial flow induced shear stress that may be sensed by the surface glycocalyx, a surface layer composed primarily of proteoglycans and glycoproteins, to mediate cell contraction during the myogenic response. We, therefore, attempted to elucidate the signal ...

journal_title：Scientific reports

authors： Kang H,Liu J,Sun A,Liu X,Fan Y,Deng X

更新日期：2017-02-13 00:00:00

abstract：:The insect vector borne bacterium Xylella fastidiosa was first detected in olive trees in Southern Italy in 2013, and identified as the main culprit behind the 'olive quick decline syndrome'. Since then, the disease has spread rapidly through Italy's main olive oil producing region. The epidemiology of the outbreak is...

journal_title：Scientific reports

authors： Strona G,Carstens CJ,Beck PS

更新日期：2017-03-06 00:00:00

abstract：:The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic cell clearance by ac...

journal_title：Scientific reports

authors： Lei X,Liu C,Azadzoi K,Li C,Lu F,Xiang A,Sun J,Guo Y,Zhao Q,Yan Z,Yang J

更新日期：2015-01-16 00:00:00

abstract：:This study was performed to compare the area of the foveal avascular zone (FAZ-area) obtained by three optical coherence tomography angiography (OCTA) instruments. This was a cross-sectional, non-interventional study of twenty-seven healthy right eyes. The superficial and deep FAZ-area was measured manually with three...

journal_title：Scientific reports

authors： Shiihara H,Sakamoto T,Yamashita T,Kakiuchi N,Otsuka H,Terasaki H,Sonoda S

更新日期：2017-08-29 00:00:00

abstract：:Solid-state spin-based qubits offer good prospects for scaling based on their long coherence times and nexus to large-scale electronic scale-up technologies. However, high-threshold quantum error correction requires a two-dimensional qubit array operating in parallel, posing significant challenges in fabrication and c...

journal_title：Scientific reports

authors： Nguyen T,Hill CD,Hollenberg LCL,James MR

更新日期：2017-10-17 00:00:00

abstract：:Receptor trafficking is pivotal for the temporal and spatial control of GPCR signaling and is regulated by multiple cellular proteins. We provide evidence that GPCRs interact with 14-3-3 signal adaptor/scaffold proteins and that this interaction regulates receptor trafficking in two ways. We found GPCR/14-3-3 interact...

journal_title：Scientific reports

authors： Yuan L,Barbash S,Kongsamut S,Eishingdrelo A,Sakmar TP,Eishingdrelo H

更新日期：2019-08-01 00:00:00

abstract：:To date, the significant anti-cancer capacity of cold atmospheric plasma (CAP) on dozens of cancer cell lines has been demonstrated in vitro and in mice models. Conventionally, CAP was directly applied to irradiate cancer cells or tumor tissue. Over past three years, the CAP irradiated media was also found to kill can...

journal_title：Scientific reports

authors： Yan D,Talbot A,Nourmohammadi N,Cheng X,Canady J,Sherman J,Keidar M

更新日期：2015-12-17 00:00:00

abstract：:Propofol sedation has been applied during esophagogastroduodenoscopy procedures, but whether topical pharyngeal anesthesia should be administered at the same time has rarely been reported. Our study examined the role of topical pharyngeal anesthesia in sedated endoscopies in a randomized controlled double-blinded clin...

journal_title：Scientific reports

authors： Sun X,Xu Y,Zhang X,Li A,Zhang H,Yang T,Liu Y

更新日期：2018-04-27 00:00:00

abstract：:BDNF and its gene polymorphism may be important in synaptic plasticity and neuron survival, and may become a key target in the physiopathology of long-term heroin use. Thus, we investigated the relationships between brain-derived neurotrophic factor (BDNF) plasma concentrations and the BDNF Val66Met nucleotide polymor...

journal_title：Scientific reports

authors： Chen SL,Lee SY,Chang YH,Wang TY,Chen SH,Chu CH,Chen PS,Yang YK,Hong JS,Lu RB

更新日期：2015-02-02 00:00:00

abstract：:Neuroinflammation is involved in the pathogenesis of Parkinson's disease (PD) and other neurodegenerative disorders. We show that lack of PINK1- a mitochondrial kinase linked to recessive familial PD - leads to glia type-specific abnormalities of innate immunity. PINK1 loss enhances LPS/IFN-γ stimulated pro-inflammato...

journal_title：Scientific reports

authors： Sun L,Shen R,Agnihotri SK,Chen Y,Huang Z,Büeler H

更新日期：2018-01-10 00:00:00

abstract：:Chicken anemia virus (CAV) is an important pathogen that causes severe immunosuppression in young chickens. We have characterized 13 CAVs isolated from different commercial farms in southern China between 2011 and 2012. We discovered 92 variable residues compared to 37 other CAV complete genome sequences from other pa...

journal_title：Scientific reports

authors： Zhang X,Liu Y,Wu B,Sun B,Chen F,Ji J,Ma J,Xie Q

更新日期：2013-12-17 00:00:00

abstract：:Although the growth of graphene by chemical vapor deposition is a production technique that guarantees high crystallinity and superior electronic properties on large areas, it is still a challenge for manufacturers to efficiently scale up the production to the industrial scale. In this context, issues related to the p...

journal_title：Scientific reports

authors： Lisi N,Dikonimos T,Buonocore F,Pittori M,Mazzaro R,Rizzoli R,Marras S,Capasso A

更新日期：2017-08-30 00:00:00

abstract：:Organ transplantation remains the most effective treatment for patients with late stage organ failure. Transgenic pigs provide an alternative organ donor source to the limited availability of human organs. However, cellular rejection still remains to be the obstacle for xenotransplantation. Superior to other methods, ...

journal_title：Scientific reports

authors： Li M,Eckl J,Geiger C,Schendel DJ,Pohla H

更新日期：2017-06-21 00:00:00

abstract：:High frequency repetitive transcranial magnetic stimulation (HF-rTMS) over the left dorsolateral prefrontal cortex (L-DLPFC) is a widely applied treatment protocol for chronic smoking and major depressive disorder. However, no previous study has measured the effects of rTMS on both nicotine consumption and anxiety/dep...

journal_title：Scientific reports

authors： Abdelrahman AA,Noaman M,Fawzy M,Moheb A,Karim AA,Khedr EM

更新日期：2021-01-15 00:00:00

abstract：:Due to the different craniocervical structures in humans and cetaceans, a standardised method assessing the normal craniocervical relationship in cetaceans is lacking, causing difficulties in defining the presence of atlanto-occipital dissociation (AOD) in cetaceans. The present study aimed to 1) describe a novel stan...

journal_title：Scientific reports

authors： Kot BCW,Chan DKP,Yuen AHL,Tsui HCL

更新日期：2018-05-31 00:00:00

abstract：:Generating various laser sources is important in the communication systems. We propose an approach that uses a mechanical resonator coupled with the optical fibre system to produce periodic and chaotic optical signals. The resonator is structured in such a way that the nonlinear oscillation occurs conveniently. The me...

journal_title：Scientific reports

authors： Jin L,Guo Y,Ji X,Li L

更新日期：2017-07-06 00:00:00

abstract：:Human CD4+ T cells play an important role in the immune response to Mycobacterium tuberculosis (MTB). However, little is known about the spectratyping characteristics of the CD4+ T-cell receptor (TCR) α- and β-chains CDR3 region in tuberculosis (TB) patients. We sorted MTB peptide E7-bound CD4+ T cells by using E7/HLA...

journal_title：Scientific reports

authors： Gan Y,Wang C,Fang Y,Yao Y,Tu X,Wang J,Huang X,Tan Y,Chen T,Zhang K,Shen Y,Zhou L,Liu J,Lai X

更新日期：2018-07-02 00:00:00

abstract：:N(1)-methyladenosine (m(1)A) is a prominent RNA modification involved in many biological processes. Accurate identification of m(1)A site is invaluable for better understanding the biological functions of m(1)A. However, limitations in experimental methods preclude the progress towards the identification of m(1)A site...

journal_title：Scientific reports

authors： Chen W,Feng P,Tang H,Ding H,Lin H

更新日期：2016-08-11 00:00:00

abstract：:Designing a new generation of energy-intensive and sustainable electrode materials for batteries to power a variety of applications is an imperative task. The use of biomaterials as a nanosized structural template for these materials has the potential to produce hitherto unachievable structures. In this report, we hav...

journal_title：Scientific reports

authors： Beznosov SN,Veluri PS,Pyatibratov MG,Chatterjee A,MacFarlane DR,Fedorov OV,Mitra S

更新日期：2015-01-13 00:00:00

abstract：:Tumour growth and metastatic colonization is strongly influenced by the tumour stroma, including cancer-associated fibroblasts (CAF). Multipotent mesenchymal stromal cells (MSC) are a possible source of CAF following myofibroblastic differentiation, and we have previously shown that MSC support tumour growth. Triggere...

journal_title：Scientific reports

authors： Werner S,Lützkendorf J,Müller T,Müller LP,Posern G

更新日期：2019-08-13 00:00:00

abstract：:Induction chemotherapy treatment for nasopharyngeal carcinoma (NPC) is controversial. The aim of this study was to evaluate the treatment outcomes and toxicities between two induction chemotherapy regimens, with both followed by concurrent chemoradiotherapy. The first strategy used docetaxel, cisplatin and fluorouraci...

journal_title：Scientific reports

authors： Zeng Z,Yan RN,Tu L,Wang YY,Chen PR,Luo F,Liu L

更新日期：2018-10-22 00:00:00

abstract：:Aggregates of corundum crystals with skeletal to hopper morphology occur in pyroclastic rocks erupted from Cretaceous basaltic volcanoes on Mt Carmel, N. Israel. The rapid growth of the crystals trapped volumes of the parental Al2O3-supersaturated melt; phenocrysts of tistarite (Ti2O3) in the trapped melts indicate cr...

journal_title：Scientific reports

authors： Oliveira B,Griffin WL,Gain SEM,Saunders M,Shaw J,Toledo V,Afonso JC,O'Reilly SY

更新日期：2021-01-28 00:00:00

abstract：:It is well recognized that osteocytes communicate with each other via gap junctions and that connxin43 (Cx43) shows its great potential in gap junction for the contribution enabling transmission of small molecules and operating in an autocrine/a paracrine manner. Fibroblast growth factors (FGFs) play significant roles...

journal_title：Scientific reports

authors： Liu XY,Li X,Bai MR,Chen X,Wang CL,Xie J,Ye L

更新日期：2018-10-04 00:00:00

abstract：:Anserine/carnosine supplementation improves cerebral blood flow and verbal episodic memory in elderly people, as we previously reported. Anserine's buffering activity is superior to that of carnosine at neutral pH. In human sera, carnosine but not anserine is rapidly cleaved by carnosinase, limiting its effectiveness....

journal_title：Scientific reports

authors： Kaneko J,Enya A,Enomoto K,Ding Q,Hisatsune T

更新日期：2017-10-03 00:00:00

abstract：:Cardiac arrhythmias are often associated with mutations in ion channels or other proteins. To enable drug development for distinct arrhythmias, model systems are required that allow implementing patient-specific mutations. We assessed a muscular pump in Caenorhabditis elegans. The pharynx utilizes homologues of most o...

journal_title：Scientific reports

authors： Schüler C,Fischer E,Shaltiel L,Steuer Costa W,Gottschalk A

更新日期：2015-09-24 00:00:00

abstract：:Amyloid formation is associated with multiple amyloidosis diseases. Human calcitonin (hCT) is a typical amyloidogenic peptide, its aggregation is associated with medullary carcinoma of the thyroid (MTC), and also limits its clinical application. Magnolia officinalis is a traditional Chinese herbal medicine; its two ma...

journal_title：Scientific reports

authors： Guo C,Ma L,Zhao Y,Peng A,Cheng B,Zhou Q,Zheng L,Huang K

更新日期：2015-09-01 00:00:00