Author Correction: Growth and longevity in giant barrel sponges: Redwoods of the reef or Pines in the Indo-Pacific?

abstract：:The over-expression and aggregation of α-synuclein (αSyn) are linked to the onset and pathology of Parkinson's disease. Native monomeric αSyn exists in an intrinsically disordered ensemble of interconverting conformations, which has made its therapeutic targeting by small molecules highly challenging. Nonetheless, her...

journal_title：Scientific reports

authors： Tóth G,Neumann T,Berthet A,Masliah E,Spencer B,Tao J,Jobling MF,Gardai SJ,Bertoncini CW,Cremades N,Bova M,Ballaron S,Chen XH,Mao W,Nguyen P,Tabios MC,Tambe MA,Rochet JC,Junker HD,Schwizer D,Sekul R,Ott I,Ander

更新日期：2019-11-18 00:00:00

abstract：:An atmospheric component of the Philippine-Taiwan Oscillations (PTOa) is used to examine its potential connection with tropical cyclone (TC) frequency in the western North Pacific in the period of 1979-2014. During positive PTOa years, more TCs are observed in the tropical western Pacific south of 18 °N where cyclonic...

journal_title：Scientific reports

authors： Chang YK,Miyazawa Y,Kodaira T,Behera S

更新日期：2018-11-29 00:00:00

abstract：:The prevalence of patients on automated peritoneal dialysis (APD) is increasing worldwide and may be guided by clinical characteristics, financial issues and patient option. Whether socioeconomic factors at the patient level may influence the decision for the initial peritoneal dialysis (PD) modality is unknown. This ...

journal_title：Scientific reports

authors： Pecoits-Filho R,Ribeiro SC,Kirk A,da Silva HS,Pille A,Falavinha RS Jr,Filho SS,Figueiredo AE,Barretti P,de Moraes TP

更新日期：2017-07-12 00:00:00

abstract：:Heme-copper oxygen reductases are terminal respiratory enzymes, catalyzing the reduction of dioxygen to water and the translocation of protons across the membrane. Oxygen consumption is inhibited by various substances. Here we tested the relatively unknown inhibition of cytochrome c oxidase (CcO) with isocyanate. In c...

journal_title：Scientific reports

authors： Kruse F,Nguyen AD,Dragelj J,Schlesinger R,Heberle J,Mroginski MA,Weidinger IM

更新日期：2020-03-02 00:00:00

abstract：:Inbred strains of mice are powerful models for understanding human pregnancy complications. For example, the exclusive mating of CBA/J females to DBA/2J males increases fetal resorption to 20-35% with an associated decline in placentation and maintenance of maternal Th1 immunity. More recently other complications of p...

journal_title：Scientific reports

authors： McKelvey KJ,Yenson VM,Ashton AW,Morris JM,McCracken SA

更新日期：2016-10-21 00:00:00

abstract：:High-entropy alloys (HEAs) have inspired considerable interest due to their attractive physical and mechanical properties. In this work, the microstructural evolution induced by different heat treatments on rapidly solidified hypoeutectic precursors of a Fe26.7Co26.7Ni26.7Si8.9B11 HEA is investigated and correlated wi...

journal_title：Scientific reports

authors： Zhang ZQ,Song KK,Guo S,Xue QS,Xing H,Cao CD,Dai FP,Völker B,Hohenwarter A,Maity T,Chawake N,Kim JT,Wang L,Kaban I,Eckert J

更新日期：2019-01-23 00:00:00

abstract：:Type 2 diabetes mellitus is a major health concern worldwide; however, the molecular mechanism underlying its development is poorly understood. The hormone amylin is postulated to be involved, as human amylin forms amyloid in the pancreases of diabetic patients, and oligomers have been shown to be cytotoxic to β-cells...

journal_title：Scientific reports

authors： Nie T,Zhang S,Vazhoor Amarsingh G,Liu H,McCann MJ,Cooper GJS

更新日期：2019-10-10 00:00:00

abstract：:Despite the fact that magnetic thrombolytic composites is an emerging area, all known so far systems are based on the similar mechanism of action: thrombolytic enzyme releases from the magnetic carrier leaving non-active matrix, thus making the whole system active only for a limited period of time. Such systems often ...

journal_title：Scientific reports

authors： Drozdov AS,Vinogradov VV,Dudanov IP,Vinogradov VV

更新日期：2016-06-20 00:00:00

abstract：:Triple-negative breast cancers (TNBC) are unlikely to respond to hormonal therapies and anti-HER2-targeted therapies. TNBCs overexpress EGFR and exhibit constitutive activation of the PI3K/AKT/mTOR signalling pathway. We hypothesized that simultaneously blocking EGFR and mTOR could be a potential therapeutic strategy ...

journal_title：Scientific reports

authors： El Guerrab A,Bamdad M,Bignon YJ,Penault-Llorca F,Aubel C

更新日期：2020-04-14 00:00:00

abstract：:This paper reports the presence of tear strips on the surface of a Ti-22Al-25Nb alloy sheet stretched at 960 °C. The test piece reveals a "bamboo"-shaped pattern on its surface, which severely affects the quality of the alloy. Microstructure analysis indicates that the formation mechanism of the tear strip is related ...

journal_title：Scientific reports

authors： Zong Y,Shao B,Xu W,Guo B,Shan D

更新日期：2017-05-10 00:00:00

abstract：:The mammalian Major Histocompatibility Complex (MHC) region contains several gene families characterized by highly polymorphic loci with extensive nucleotide diversity, copy number variation of paralogous genes, and long repetitive sequences. This structural complexity has made it difficult to construct a reliable ref...

journal_title：Scientific reports

authors： Viļuma A,Mikko S,Hahn D,Skow L,Andersson G,Bergström TF

更新日期：2017-03-31 00:00:00

abstract：:Magnetic carboxyl functional nanoporous polymer (MCFNP) was chemically fabricated by incorporation of magnetic Fe3O4 precursor into the carboxyl functional nanoporous polymer (CFNP). The as-synthesized MCFNP was characterized and used as an adsorbent for rapid adsorption removal of methylene blue (MB) from wastewater....

journal_title：Scientific reports

authors： Su H,Li W,Han Y,Liu N

更新日期：2018-04-25 00:00:00

abstract：:Obese individuals can be categorized as "healthy obese" (MHO) and "unhealthy obese" (MUO) based on the presence or absence of metabolic abnormality. This study sets out to assess potential genetic causes behind persistence of healthy metabolic status in individuals categorized as "healthy obese". This study was conduc...

journal_title：Scientific reports

authors： Gharooi Ahangar O,Javanrouh N,Daneshpour MS,Barzin M,Valizadeh M,Azizi F,Hosseinpanah F

更新日期：2020-08-12 00:00:00

abstract：:There is a growing interest in developing microphysiological systems that can be used to model both normal and pathological human organs in vitro. This "organs-on-chips" approach aims to capture key structural and physiological characteristics of the target tissue. Here we describe in vitro vascularized microtumors (V...

journal_title：Scientific reports

authors： Sobrino A,Phan DT,Datta R,Wang X,Hachey SJ,Romero-López M,Gratton E,Lee AP,George SC,Hughes CC

更新日期：2016-08-23 00:00:00

abstract：:Primary human hepatocytes are necessary to evaluate cytotoxicity, drug metabolism, and drug-drug interactions for candidate compounds in early-phase drug discovery and development. However, these analyses are often hampered by limited resources and functional or genetic variation among lots. HepaRG human hepatocellula...

journal_title：Scientific reports

authors： Ueyama T,Tsuji S,Sugiyama T,Tada M

更新日期：2017-06-06 00:00:00

abstract：:Baroreflex dysfunction is a diffuse chronic condition that is expected to be followed by a profound loss of organization of BP and HR variability. Nevertheless, long-term effects of baroreflex withdrawal are still debated. Aim of our work was to study BP and HR changes long term after sino-aortic denervation (SAD). In...

journal_title：Scientific reports

authors： Radaelli A,Mancia G,De Carlini C,Soriano F,Castiglioni P

更新日期：2019-02-04 00:00:00

abstract：:Hfq is a pleiotropic regulator that mediates several aspects of bacterial RNA metabolism. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, usually via its interaction with small regulatory RNA. Besides these RNA-related functions, Hfq has also been described as one of the n...

journal_title：Scientific reports

authors： Malabirade A,Partouche D,El Hamoui O,Turbant F,Geinguenaud F,Recouvreux P,Bizien T,Busi F,Wien F,Arluison V

更新日期：2018-11-14 00:00:00

abstract：:Acute-on-chronic liver failure (ACLF) is a dynamic syndrome, and sequential assessments can reflect its prognosis more accurately. Our aim was to build and validate a new scoring system to predict short-term prognosis using baseline and dynamic data in ACLF. We conducted a retrospective cohort analysis of patients wit...

journal_title：Scientific reports

authors： Yu Z,Zhang Y,Cao Y,Xu M,You S,Chen Y,Zhu B,Kong M,Song F,Xin S,Duan Z,Han T

更新日期：2021-01-19 00:00:00

abstract：:Circadian disruption resulting from exposure to irregular light-dark patterns and sleep deprivation has been associated with beta amyloid peptide (Aβ) aggregation, which is a major event in Alzheimer's disease (AD) pathology. We exposed 5XFAD mice and littermate controls to dim-light vs. bright-light photophases to in...

journal_title：Scientific reports

authors： Nagare R,Possidente B,Lagalwar S,Figueiro MG

更新日期：2020-07-10 00:00:00

abstract：:Ligninolytic peroxidases are microbial enzymes involved in depolymerisation of lignin, a plant cell wall polymer found in land plants. Among fungi, only Dikarya were found to degrade lignin. The increase of available fungal genomes allows performing an expert annotation of lignin-degrading peroxidase encoding sequence...

journal_title：Scientific reports

authors： Mathé C,Fawal N,Roux C,Dunand C

更新日期：2019-12-30 00:00:00

abstract：:Enhancers play a crucial role in gene regulation but the participation of enhancer transcripts (i.e. enhancer RNA, eRNAs) in regulatory systems remains unclear. We provide a computational analysis on eRNAs using genome-wide data across 12 mouse tissues. The expression of genes targeted by transcribing enhancer is posi...

journal_title：Scientific reports

authors： Cheng JH,Pan DZ,Tsai ZT,Tsai HK

更新日期：2015-07-29 00:00:00

abstract：:Haze is a serious issue in China with increasing concerns, and understanding the factors driving decadal-scale variations in haze occurrence is relevant for government policymaking. Using a comprehensive observational haze dataset, we demonstrate notable decadal fluctuations in the number of haze days (HD) during wint...

journal_title：Scientific reports

authors： Zhao S,Li J,Sun C

更新日期：2016-06-10 00:00:00

abstract：:The indiscriminate use of antibiotics has led to the emergence of drug-resistant bacteria which has become one of the biggest challenges of the twenty-first century for the researchers to combat and in turn search for novel targets which could lead to the development of effective and sustainable therapies. Inhibition ...

journal_title：Scientific reports

authors： Prateeksha,Barik SK,Singh BN

更新日期：2019-04-24 00:00:00

abstract：:Medulloblastoma (MB), the most common malignant paediatric brain tumour occurs in the cerebellum. Advances in molecular genomics have led to the identification of defined subgroups which are associated with distinct clinical prognoses. Despite this classification, standard therapies for all subgroups often leave child...

journal_title：Scientific reports

authors： Mather RL,Loveson KF,Fillmore HL

更新日期：2019-06-13 00:00:00

abstract：:Nickel-titanium-oxide (Ni-Ti-O) nanotube arrays (NTAs) prepared on nearly equiatomic NiTi alloy shall have broad application potential such as for energy storage and biomedicine, but their precise structure control is a great challenge because of the high content of alloying element of Ni, a non-valve metal that canno...

journal_title：Scientific reports

authors： Hang R,Liu Y,Zhao L,Gao A,Bai L,Huang X,Zhang X,Tang B,Chu PK

更新日期：2014-12-18 00:00:00

abstract：:Coherent, optically dressed media composed of two-level molecular systems without inversion symmetry are considered as all-optically tunable sources of coherent radiation in the microwave domain. A theoretical model and a numerical toolbox are developed to confirm the main finding: the generation of low-frequency radi...

journal_title：Scientific reports

authors： Gładysz P,Wcisło P,Słowik K

更新日期：2020-10-19 00:00:00

abstract：:Frequency shifts in signals of bats flying near conspecifics have been interpreted as a spectral jamming avoidance response (JAR). However, several prerequisites supporting a JAR hypothesis have not been controlled for in previous studies. We recorded flight and echolocation behavior of foraging Pipistrellus pipistrel...

journal_title：Scientific reports

authors： Götze S,Koblitz JC,Denzinger A,Schnitzler HU

更新日期：2016-08-09 00:00:00

abstract：:The anisotropic shape of DNA molecules allows them to form lyotropic liquid crystals (LCs) at high concentrations. This liquid crystalline arrangement is also found in vivo (e.g., in bacteriophage capsids, bacteria or human sperm nuclei). However, the role of DNA liquid crystalline organization in living organisms sti...

journal_title：Scientific reports

authors： Brach K,Hatakeyama A,Nogues C,Olesiak-Banska J,Buckle M,Matczyszyn K

更新日期：2018-03-14 00:00:00

abstract：:We demonstrate a label-free imaging approach to study cardiac remodeling of fibrotic and hypertrophic hearts, bridging scales from the whole organ down to the molecular level. To this end, we have used mice subjected to transverse aortic constriction and imaged adjacent cardiac tissue sections by microfocus X-ray diff...

journal_title：Scientific reports

authors： Nicolas JD,Khan A,Markus A,Mohamed BA,Toischer K,Alves F,Salditt T

更新日期：2020-11-09 00:00:00

abstract：:HLA-haploidentical hematopoietic stem cell transplantation (HSCT) may be an option for severe aplastic anemia (SAA) patients. However, to date, no large-sample studies have been performed to determine which types of SAA patients are suitable for HLA-haploidentical HSCT. We retrospectively studied 189 consecutive patie...

journal_title：Scientific reports

authors： Zeng Y,Wang S,Wang J,Liu L,Su Y,Lu Z,Zhang X,Zhang Y,Zhong JF,Peng L,Liu Q,Lu Y,Gao L,Zhang X

更新日期：2018-02-06 00:00:00