Evaluation of Serological and Molecular Tests Used for the Identification of Toxoplasma gondii Infection in Patients Treated in an Ophthalmology Clinic of a Public Health Service in São Paulo State, Brazil.

abstract：:HIGHLIGHTS What is already known about this subject?Celiac disease (CD) has a high clinical and histological diversity and the mechanisms underlying this phenomenon remain elusive.H. pylori is a bacterium that chronically infect gastric and duodenal mucosa activating both a Th1/Th17 and T-reg pathways.The role of H. p...

journal_title：Frontiers in cellular and infection microbiology

authors： Lucero Y,Oyarzún A,O'Ryan M,Quera R,Espinosa N,Valenzuela R,Simian D,Alcalde E,Arce C,Farfán MJ,Vergara AF,Gajardo I,Mendez J,Carrasco J,Errázuriz G,Gonzalez M,Ossa JC,Maiza E,Perez-Bravo F,Castro M,Araya M

更新日期：2017-08-23 00:00:00

abstract：:Herpes simplex virus-1 (HSV-1) is a significant human pathogen. Upon infection, HSV-1 expresses its immediate early (IE) genes, and the IE transcription factor ICP4 (infectious cell protein-4) plays a pivotal role in initiating the downstream gene-expression cascade. Using live-cell time-lapse fluorescence microscopy,...

journal_title：Frontiers in cellular and infection microbiology

authors： Chaturvedi S,Engel R,Weinberger L

更新日期：2020-06-24 00:00:00

abstract：:Non-optimal vaginal microbiota, as observed in bacterial vaginosis (BV), is typically characterized by a depletion of beneficial lactobacilli and an abundance of numerous anaerobes. These non-optimal conditions are associated with subclinical cervicovaginal inflammation and an increased risk of HIV infection compared ...

journal_title：Frontiers in cellular and infection microbiology

authors： Delgado-Diaz DJ,Tyssen D,Hayward JA,Gugasyan R,Hearps AC,Tachedjian G

更新日期：2020-01-10 00:00:00

abstract：:Acute pancreatitis (AP) is considered a cascade of immune responses triggered by acinar cell necrosis. AP involves two main processes of systemic inflammatory response syndrome and subsequent compensatory anti-inflammatory response syndrome. Although great efforts have been made regarding AP therapy, the mortality rat...

journal_title：Frontiers in cellular and infection microbiology

authors： Ding L,Yang Y,Li H,Wang H,Gao P

更新日期：2020-03-31 00:00:00

abstract：:Cold shock-domain family proteins (Csps) are highly conserved nucleic acid binding proteins regulating the expression of various genes including those involved in stress resistance and virulence in bacteria. We show here that Csps are involved in virulence, cell aggregation and flagella-based extracellular motility of...

journal_title：Frontiers in cellular and infection microbiology

authors： Eshwar AK,Guldimann C,Oevermann A,Tasara T

更新日期：2017-10-26 00:00:00

abstract：:Due to increased travel, climatic, and environmental changes, the incidence of tick-borne disease in both humans and animals is increasing throughout Europe. Therefore, extended surveillance tools are desirable. To accurately screen tick-borne pathogens (TBPs), a large scale epidemiological study was conducted on 7050...

journal_title：Frontiers in cellular and infection microbiology

authors： Michelet L,Delannoy S,Devillers E,Umhang G,Aspan A,Juremalm M,Chirico J,van der Wal FJ,Sprong H,Boye Pihl TP,Klitgaard K,Bødker R,Fach P,Moutailler S

更新日期：2014-07-29 00:00:00

abstract：:Francisella tularensis can bypass and suppress host immune responses, even to the point of manipulating immune cell phenotypes and intercellular inflammatory networks. Strengthening these responses such that immune cells more readily identify and destroy the bacteria is likely to become a viable (and perhaps necessary...

journal_title：Frontiers in cellular and infection microbiology

authors： Gillette DD,Tridandapani S,Butchar JP

更新日期：2014-02-21 00:00:00

abstract：:The worldwide increase in antibiotic-resistant pathogens means that identification of alternative antibacterial drug targets and the subsequent development of new treatment strategies are urgently required. One such new target is the quorum sensing (QS) system. Coral microbial consortia harbor an enormous diversity of...

journal_title：Frontiers in cellular and infection microbiology

authors： Ma ZP,Song Y,Cai ZH,Lin ZJ,Lin GH,Wang Y,Zhou J

更新日期：2018-05-08 00:00:00

abstract：:The hemostatic system comprises platelet aggregation, coagulation and fibrinolysis and is a host defense mechanism that protects the integrity of the vascular system after tissue injury. During bacterial infections, the coagulation system cooperates with the inflammatory system to eliminate the invading pathogens. How...

journal_title：Frontiers in cellular and infection microbiology

authors： Loof TG,Deicke C,Medina E

更新日期：2014-09-11 00:00:00

abstract：:The cell envelope of pathogenic bacteria is a barrier against host environmental conditions and immunity molecules, as well as the site where many virulence factors are assembled. Extracytoplasmic stress responses (ESRs) have evolved to help maintain its integrity in conditions where it might be compromised. These ESR...

journal_title：Frontiers in cellular and infection microbiology

authors： Flores-Kim J,Darwin AJ

更新日期：2012-10-10 00:00:00

abstract：:Background and Purpose: Early life microbiota plays a crucial role in human health by acting as a barrier from pathogens' invasion and maintaining the intestinal immune homoeostasis. Altered fecal microbiota (FM) ecology was reported in newborns affected by intestinal ischemia. Our purpose was to describe, in these pa...

journal_title：Frontiers in cellular and infection microbiology

authors： Romani L,Del Chierico F,Chiriaco M,Foligno S,Reddel S,Salvatori G,Cifaldi C,Faraci S,Finocchi A,Rossi P,Bagolan P,D'Argenio P,Putignani L,Fusaro F

更新日期：2020-02-25 00:00:00

abstract：:The emerging relapsing fever spirochete Borrelia (B.) miyamotoi is transmitted by ixodid ticks and causes the so-called hard tick-borne relapsing fever or B. miyamotoi disease (BMD). More recently, we identified a surface-exposed molecule, CbiA exhibiting complement binding and inhibitory capacity and rendering spiroc...

journal_title：Frontiers in cellular and infection microbiology

authors： Nguyen NTT,Röttgerding F,Devraj G,Lin YP,Koenigs A,Kraiczy P

更新日期：2018-02-02 00:00:00

abstract：:Pneumocystis pneumonia (PCP) remains the most frequent AIDS-defining illness in developed countries. This infection also occurs in non-AIDS immunosuppressed patients, e.g., those who have undergone an organ transplantation. Moreover, mild Pneumocystis jirovecii infections related to low pulmonary fungal burden, freque...

journal_title：Frontiers in cellular and infection microbiology

authors： Bonnet P,Le Gal S,Calderon E,Delhaes L,Quinio D,Robert-Gangneux F,Ramel S,Nevez G

更新日期：2020-09-29 00:00:00

abstract：:The Asian tiger mosquito Aedes (Stegomya) albopictus is an invasive species that has spread across the world in the last two decades, showing a great capacity to adapt to contrasting climates and environments. While demonstrated in many insects, the contribution of bacterial symbionts in Aedes ecology is a challenging...

journal_title：Frontiers in cellular and infection microbiology

authors： Minard G,Tran FH,Dubost A,Tran-Van V,Mavingui P,Moro CV

更新日期：2014-05-14 00:00:00

abstract：:Cell death can be critical for host defense against intracellular pathogens because it eliminates a crucial replicative niche, and pro-inflammatory cell death can alert neighboring cells to the presence of pathogenic organisms and enhance downstream immune responses. Pyroptosis is a pro-inflammatory form of cell death...

journal_title：Frontiers in cellular and infection microbiology

authors： Casson CN,Shin S

更新日期：2013-12-27 00:00:00

abstract：:Objectives:Pneumocystis jirovecii pneumonia (PCP) is an AIDS-defining illness. In patients with HIV, the benefit of PCP prophylaxis is well-defined when the CD4 T-cell count decreases below 200 cells/μL. In other immunocompromised patients, the value of PCP prophylaxis is not always as well-established. This study aim...

journal_title：Frontiers in cellular and infection microbiology

authors： Dunbar A,Schauwvlieghe A,Algoe S,van Hellemond JJ,Reynders M,Vandecasteele S,Boelens J,Depuydt P,Rijnders B

更新日期：2020-05-15 00:00:00

abstract：:Murid and cricetid rodents were previously believed to be the principal reservoir hosts of hantaviruses. Recently, however, multiple newfound hantaviruses have been discovered in shrews, moles, and bats, suggesting a complex evolutionary history. Little is known about the genetic diversity and geographic distribution ...

journal_title：Frontiers in cellular and infection microbiology

authors： Kikuchi F,Aoki K,Ohdachi SD,Tsuchiya K,Motokawa M,Jogahara T,Sơn NT,Bawm S,Lin KS,Thwe TL,Gamage CD,Ranorosoa MC,Omar H,Maryanto I,Suzuki H,Tanaka-Taya K,Morikawa S,Mizutani T,Suzuki M,Yanagihara R,Arai S

更新日期：2020-08-27 00:00:00

abstract：:Overwhelming cardiac inflammation has been reported to be the pathogenic mechanism of Coxsackievirus B3 (CVB3)-induced viral myocarditis (VMC), while the detailed molecular mechanisms remain unknown. Membrane-bound dipeptidases (MBD, also known as Dpep) have been shown to be involved in inflammatory diseases. However,...

journal_title：Frontiers in cellular and infection microbiology

authors： Yang X,Yue Y,Xiong S

更新日期：2019-03-07 00:00:00

abstract：:Syf1 is a tetratricopeptide repeat (TPR) protein implicated in transcription elongation, spliceosome conformation, mRNA nuclear-cytoplasmic export and transcription-coupled DNA repair. Recently, we identified the spliceosomal components of the human parasite Entamoeba histolytica, among them is EhSyf. Molecular predic...

journal_title：Frontiers in cellular and infection microbiology

authors： Torres-Cifuentes DM,Galindo-Rosales JM,Saucedo-Cárdenas O,Valdés J

更新日期：2018-07-09 00:00:00

abstract：:Magnaporthe oryzae (Mo) is a model pathogen causing rice blast resulting in yield and economic losses world-wide. CK2 is a constitutively active, serine/threonine kinase in eukaryotes, having a wide array of known substrates, and involved in many cellular processes. We investigated the localization and role of MoCK2 d...

journal_title：Frontiers in cellular and infection microbiology

authors： Zhang L,Zhang D,Chen Y,Ye W,Lin Q,Lu G,Ebbole DJ,Olsson S,Wang Z

更新日期：2019-04-17 00:00:00

abstract：:More than a decade ago a short tandem repeat-based typing method was developed for the fungus Aspergillus fumigatus. This STRAf assay is based on the analysis of nine short tandem repeat markers. Interpretation of this STRAf assay is complicated when there are only one or two differences in tandem repeat markers betwe...

journal_title：Frontiers in cellular and infection microbiology

authors： de Groot T,Meis JF

更新日期：2019-03-29 00:00:00

abstract：:The protozoan Trypanosoma cruzi is the etiological agent of Chagas disease. In immunosuppressed individuals, as it occurs in the coinfection with human immunodeficiency virus (HIV), the central nervous system may be affected. In this regard, reactivation of Chagas disease is severe and often lethal, and it accounts fo...

journal_title：Frontiers in cellular and infection microbiology

authors： Urquiza JM,Burgos JM,Ojeda DS,Pascuale CA,Leguizamón MS,Quarleri JF

更新日期：2017-08-02 00:00:00

abstract：:Pediculus humanus is an obligate bloodsucking ectoparasite of human that includes two ecotypes, head louse and body louse, which differ slightly in morphology and biology, but have distinct ecologies. Phylogenetically, they are classified on six mitochondrial clades (A, B, C, D, E, and F), head louse encompasses the f...

journal_title：Frontiers in cellular and infection microbiology

authors： Amanzougaghene N,Fenollar F,Raoult D,Mediannikov O

更新日期：2020-01-21 00:00:00

abstract：:Background: The pathogenesis of inflammatory bowel disease (IBD) is linked to an intricate association of environmental, microbial, and host-related factors. Polysaccharide affects host immunity by regulating the composition and metabolism of gut microbiota is the common mechanism of disease resistance. However, the e...

journal_title：Frontiers in cellular and infection microbiology

authors： Su L,Mao C,Wang X,Li L,Tong H,Mao J,Ji,Lu T,Hao M,Huang Z,Fei C,Zhang K,Yan G

更新日期：2020-10-21 00:00:00

abstract：:Prompt and effective elicitation of protective immunity is highly relevant for cases of rapidly deteriorating fatal diseases, such as plague, which is caused by Yersinia pestis. Here, we assessed the potential of a live vaccine to induce rapid protection against this infection. We demonstrated that the Y. pestis EV76 ...

journal_title：Frontiers in cellular and infection microbiology

authors： Zauberman A,Vagima Y,Tidhar A,Aftalion M,Gur D,Rotem S,Chitlaru T,Levy Y,Mamroud E

更新日期：2017-06-21 00:00:00

abstract：:Due to the importance of a rapid determination of patients infected by multidrug resistant bacteria, we evaluated two rapid diagnostic tests for the detection of third-generation cephalosporins (3GC)-resistant Enterobacterales directly from positive blood cultures within 1 h: BL-REDTM (electrochemical method) and β-LA...

journal_title：Frontiers in cellular and infection microbiology

authors： Durand C,Boudet A,Lavigne JP,Pantel A

更新日期：2020-09-11 00:00:00

abstract：:Toxoplasma gondii has been found to infect almost all warm-blooded animals, including humans. In this study, a total of 3,275 human serum samples were collected from hospitals in five provinces of China. About 5.13% (168/3,275) (95% CI, 4.42-5.94) of the serum samples tested positive for T. gondii IgG antibody by a mo...

journal_title：Frontiers in cellular and infection microbiology

authors： Xin S,Su R,Jiang N,Zhang L,Yang Y

更新日期：2020-06-23 00:00:00

abstract：:In the present study, we determined the in vitro characteristics and binding interactions of chicken PD-1 (chPD-1) and PD-L1 (chPD-L1) and developed a panel of specific monoclonal antibodies against the two proteins. ChPD-1 and chPD-L1 sequence identities and similarities were lower compared with those of humans and o...

journal_title：Frontiers in cellular and infection microbiology

authors： Reddy VRAP,Mwangi W,Sadigh Y,Nair V

更新日期：2019-12-19 00:00:00

abstract：:Previous studies demonstrated that oral antibiotic (ABX) treatment prior to and during influenza A virus (IAV) infection of adult mice profoundly altered gut microbiota (GM) and was associated with increased susceptibility and impaired immunity to IAV. We examined the impact of ABX during critical times relevant to th...

journal_title：Frontiers in cellular and infection microbiology

authors： Fuglsang E,Pizzolla A,Krych L,Nielsen DS,Brooks AG,Frøkiær H,Reading PC

更新日期：2018-09-12 00:00:00

abstract：:Platycodin D, extract from the root of Platycodon grandiflorum, is one of the most important monomers of the Qinbaiqingfei pellets (Qinbai) that has already been approved as the first Traditional Chinese Medicine for clinic use as an anti-M. pneumoniae agent. Qinbai constituents Scutellaria baicalensis and Platycodon ...

journal_title：Frontiers in cellular and infection microbiology

authors： Meng Y,Yang Y,Lu W,Wang Y,Qian F,Wang X,Zhang Z,Wang W

更新日期：2015-01-13 00:00:00