Links between type III secretion and extracytoplasmic stress responses in Yersinia.

abstract：:Ocular toxoplasmosis is one of the most common complications caused by the infection with the parasite Toxoplasma gondii. The risk of developing eye lesions and impaired vision is considered higher in Brazil than other countries. The clinical diagnosis is difficult and the use of sensitive and specific laboratorial me...

journal_title：Frontiers in cellular and infection microbiology

authors： Murata FHA,Previato M,Frederico FB,Barbosa AP,Nakashima F,de Faria GM Jr,Silveira Carvalho AP,Meira Strejevitch CDS,Pereira-Chioccola VL,Castiglioni L,de Mattos LC,Siqueira RC,Brandão de Mattos CC

更新日期：2020-02-07 00:00:00

abstract：:Burkholderia mallei (Bm) is a highly infectious intracellular pathogen classified as a category B biological agent by the Centers for Disease Control and Prevention. After respiratory exposure, Bm establishes itself within host macrophages before spreading into major organ systems, which can lead to chronic infection,...

journal_title：Frontiers in cellular and infection microbiology

authors： Bozue JA,Chaudhury S,Amemiya K,Chua J,Cote CK,Toothman RG,Dankmeyer JL,Klimko CP,Wilhelmsen CL,Raymond JW,Zavaljevski N,Reifman J,Wallqvist A

更新日期：2016-02-26 00:00:00

abstract：:Brucella spp. cause undulant fever in humans and brucellosis in variety of other animals. Both innate and adaptive immunity have been shown to be important in controlling Brucella infection. Toll-like receptors (TLRs) represent a group of pattern recognition receptors (PRRs) that play critical roles in the host innate...

journal_title：Frontiers in cellular and infection microbiology

authors： Pei J,Ding X,Fan Y,Rice-Ficht A,Ficht TA

更新日期：2012-09-07 00:00:00

abstract：:LeuO is a conserved and pleiotropic transcription regulator, antagonist of the nucleoid-associated silencer protein H-NS, and important for pathogenicity and multidrug resistance in Enterobacteriaceae. Regulation of transcription of the leuO gene is complex. It is silenced by H-NS and its paralog StpA, and it is autor...

journal_title：Frontiers in cellular and infection microbiology

authors： Breddermann H,Schnetz K

更新日期：2016-09-16 00:00:00

abstract：:The human-specific pathogen Salmonella enterica serovar Typhi causes typhoid, a major public health issue in developing countries. Several aspects of its pathogenesis are still poorly understood. S. Typhi possesses 14 fimbrial gene clusters including 12 chaperone-usher fimbriae (stg, sth, bcf, fim, saf, sef, sta, stb,...

journal_title：Frontiers in cellular and infection microbiology

authors： Dufresne K,Saulnier-Bellemare J,Daigle F

更新日期：2018-02-08 00:00:00

abstract：:Dengue virus (DENV) threatens almost 70% of the world's population, with no therapeutic currently available. The severe, potentially lethal forms of DENV disease (dengue hemorrhagic fever/dengue shock syndrome) are associated with the production of high level of cytokines, elicited as part of the host antiviral respon...

journal_title：Frontiers in cellular and infection microbiology

authors： Giovannoni F,Ladelfa MF,Monte M,Jans DA,Hemmerich P,García C

更新日期：2019-08-13 00:00:00

abstract：:Bacterial persisters are a small proportion of phenotypically heterogeneous variants with the transient capability to survive in high concentrations of antibiotics, causing recurrent infections in both human and aquatic animals. Transfer-messenger RNA (tmRNA), which was encoded by the ssrA gene, was identified as a de...

journal_title：Frontiers in cellular and infection microbiology

authors： Yu W,Li D,Li H,Tang Y,Tang H,Ma X,Liu Z

更新日期：2020-02-28 00:00:00

abstract：:The ability of the opportunistic pathogen, Staphylococcus aureus, to form biofilms is increasingly being viewed as an important contributor to chronic infections. In vitro methods for analyzing S. aureus biofilm formation have focused on bacterial attachment and accumulation on abiotic surfaces, such as in microtiter ...

journal_title：Frontiers in cellular and infection microbiology

authors： Walker JN,Horswill AR

更新日期：2012-03-27 00:00:00

abstract：:Understanding the systems biology approaches for promoting the development of new therapeutic drugs is attaining importance nowadays. The threat of COVID-19 outbreak needs to be vanished for global welfare, and every section of research is focusing on it. There is an opportunity for finding new, quick, and accurate to...

journal_title：Frontiers in cellular and infection microbiology

authors： Jaiswal S,Kumar M,Mandeep,Sunita,Singh Y,Shukla P

更新日期：2020-10-28 00:00:00

abstract：:The oral microbiome can play a role in the instigation and progression of oral diseases that can manifest into other systemic conditions. These associations encourage the exploration of oral dysbiosis leading to the pathogenesis of cancers. In this study, oral rinse was used to characterize the oral microbiome fluctua...

journal_title：Frontiers in cellular and infection microbiology

authors： Lim Y,Fukuma N,Totsika M,Kenny L,Morrison M,Punyadeera C

更新日期：2018-08-03 00:00:00

abstract：:Apicomplexan parasites, such as human malaria parasites, have complex lifecycles encompassing multiple and diverse environmental niches. Invading, replicating, and escaping from different cell types, along with exploiting each intracellular niche, necessitate large and dynamic changes in parasite morphology and cellul...

journal_title：Frontiers in cellular and infection microbiology

authors： Ferreira JL,Heincke D,Wichers JS,Liffner B,Wilson DW,Gilberger TW

更新日期：2021-01-08 00:00:00

abstract：:Proton pump inhibitors (PPIs) are the standard therapy for gastroesophageal reflux disease. In adults, PPI treatment is associated with Clostridium difficile infections (CDI). In contrast to adults the microbiome of infants develops from sterility at birth toward an adult-like profile in the first years of life. The e...

journal_title：Frontiers in cellular and infection microbiology

authors： Castellani C,Singer G,Kashofer K,Huber-Zeyringer A,Flucher C,Kaiser M,Till H

更新日期：2017-10-11 00:00:00

abstract：:We have previously demonstrated that Candida albicans induces differentiation of hematopoietic stem and progenitor cells (HSPCs) toward the myeloid lineage both in vitro and in vivo in a TLR2- and Dectin-1-dependent manner, giving rise to functional macrophages. In this work, we used an ex vivo model to investigate th...

journal_title：Frontiers in cellular and infection microbiology

authors： Martínez A,Bono C,Megías J,Yáñez A,Gozalbo D,Gil ML

更新日期：2018-09-03 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) represents the etiological agent for several human malignancies, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD), which are mostly seen in immunocompromised patients. In fact, KSHV has developed many strategies ...

journal_title：Frontiers in cellular and infection microbiology

authors： Barrett L,Chen J,Dai L,Plaisance-Bonstaff K,Del Valle L,Qin Z

更新日期：2020-10-30 00:00:00

abstract：:Visceral leishmaniasis is a neglected tropical disease caused by Leishmania (L.) donovani parasite in the Indian subcontinent. Macrophages (mϕ) are the harboring cells for parasite and their interactions dictate the pathogenesis of this disease. Polyunsaturated fatty acids are an integral part of the mϕ cell membrane ...

journal_title：Frontiers in cellular and infection microbiology

authors： Saini S,Rai AK

更新日期：2020-08-07 00:00:00

abstract：:The emergence of antimicrobial-resistant (AR) Salmonella has a major concern worldwide. This study was designed to determine the AR profiles and serovars distribution of Salmonella enterica isolated from different breeds of breeder chickens in the province of Henan, China. For this, 2,139 dead embryo samples were coll...

journal_title：Frontiers in cellular and infection microbiology

authors： Xu Y,Zhou X,Jiang Z,Qi Y,Ed-Dra A,Yue M

更新日期：2020-09-15 00:00:00

abstract：:For decades, mass drug treatment with praziquantel (PZQ) has been utilized to treat schistosomiasis, yet reinfection and the risk of drug resistance are among the various factors precluding successful elimination of schistosomiasis. Tractable models that replicate "real world" field conditions are crucial to effective...

journal_title：Frontiers in cellular and infection microbiology

authors： Melkus MW,Le L,Siddiqui AJ,Molehin AJ,Zhang W,Lazarus S,Siddiqui AA

更新日期：2020-02-24 00:00:00

abstract：:MiRNAs are important post-transcriptional regulators of gene expression. MiRNA expression is a crucial part of host responses to bacterial infection, however there is limited knowledge of their impact on the outcome of infections. We investigated the influence of miR-21 on macrophage responses during infection with Li...

journal_title：Frontiers in cellular and infection microbiology

authors： Johnston DGW,Kearney J,Zasłona Z,Williams MA,O'Neill LAJ,Corr SC

更新日期：2017-05-23 00:00:00

abstract：:Objective:Streptococcus pneumoniae colonizes the nasopharynx of children, and from nasopharynx it could migrate to the middle ear and causes acute otitis media (AOM). During colonization and AOM, the pneumococcus forms biofilms. In vitro biofilm formation requires a functional LuxS/AI-2 quorum-sensing system. We inves...

journal_title：Frontiers in cellular and infection microbiology

authors： Yadav MK,Vidal JE,Go YY,Kim SH,Chae SW,Song JJ

更新日期：2018-05-04 00:00:00

abstract：:Mycoplasma bovis is an important cause of bovine respiratory disease worldwide. To understand its virulence mechanisms, we sequenced three attenuated M. bovis strains, P115, P150, and P180, which were passaged in vitro 115, 150, and 180 times, respectively, and exhibited progressively decreasing virulence. Comparative...

journal_title：Frontiers in cellular and infection microbiology

authors： Rasheed MA,Qi J,Zhu X,Chenfei H,Menghwar H,Khan FA,Zhao G,Zubair M,Hu C,Chen Y,Chen H,Guo A

更新日期：2017-05-11 00:00:00

abstract：:Herpes simplex virus-1 (HSV-1) is a significant human pathogen. Upon infection, HSV-1 expresses its immediate early (IE) genes, and the IE transcription factor ICP4 (infectious cell protein-4) plays a pivotal role in initiating the downstream gene-expression cascade. Using live-cell time-lapse fluorescence microscopy,...

journal_title：Frontiers in cellular and infection microbiology

authors： Chaturvedi S,Engel R,Weinberger L

更新日期：2020-06-24 00:00:00

abstract：:Increased numbers of peripheral blood mononucleocytes (PBMC) and increased IFN-γ secretion following in vitro challenge of blood samples with soluble Leishmania antigen (SLA), have been proposed as biomarkers of specific cell-mediated immunity, indicating that treatment of visceral leishmaniasis (VL) has been successf...

journal_title：Frontiers in cellular and infection microbiology

authors： Botana L,Matía B,San Martin JV,Romero-Maté A,Castro A,Molina L,Fernandez L,Ibarra-Meneses A,Aguado M,Sánchez C,Horrillo L,Chicharro C,Nieto J,Ortega S,Ruiz-Giardin JM,Carrillo E,Moreno J

更新日期：2018-11-13 00:00:00

abstract：:Salmonella are common enteric bacterial pathogens that infect both humans and animals. Intestinal epithelial barrier, formed by a single layer of epithelial cells and apical junctional complex (AJC), plays a crucial role in host defense against enteric pathogens to prevent bacterial translocation. However, the underly...

journal_title：Frontiers in cellular and infection microbiology

authors： Sun L,Yang S,Deng Q,Dong K,Li Y,Wu S,Huang R

更新日期：2020-12-17 00:00:00

abstract：:Metagenomic approaches applied to viruses have highlighted their prevalence in almost all microbial ecosystems investigated. In all ecosystems, notably those associated with humans or animals, the viral fraction is dominated by bacteriophages. Whether they contribute to dysbiosis, i.e., the departure from microbiota c...

journal_title：Frontiers in cellular and infection microbiology

authors： De Paepe M,Leclerc M,Tinsley CR,Petit MA

更新日期：2014-03-28 00:00:00

abstract：:Sortases function as cysteine transpeptidases that catalyze the covalent attachment of virulence-associated surface proteins into the cell wall peptidoglycan in Gram-positive bacteria. The substrate proteins targeted by sortase enzymes have a cell wall sorting signal (CWSS) located at the C-terminus. Up to date, it is...

journal_title：Frontiers in cellular and infection microbiology

authors： Yin JC,Fei CH,Lo YC,Hsiao YY,Chang JC,Nix JC,Chang YY,Yang LW,Huang IH,Wang S

更新日期：2016-11-22 00:00:00

abstract：:In this study, a next-generation sequencing strategy on 16S ribosomal RNA (16S rRNA) gene was employed to analyze 70 oral samples from 32 patients with throat cancer, nine patients with vocal cord polyp, and 29 healthy individuals (normal controls). Using this strategy, we demonstrated, for the first time, that the sa...

journal_title：Frontiers in cellular and infection microbiology

authors： Wang L,Yin G,Guo Y,Zhao Y,Zhao M,Lai Y,Sui P,Shi T,Guo W,Huang Z

更新日期：2019-07-03 00:00:00

abstract：:The natural history of genital Chlamydia trachomatis infections can vary widely; infections can spontaneously resolve but can also last from months to years, potentially progressing to cause significant pathology. The host and bacterial factors underlying this wide variation are not completely understood, but emphasiz...

journal_title：Frontiers in cellular and infection microbiology

authors： Aiyar A,Quayle AJ,Buckner LR,Sherchand SP,Chang TL,Zea AH,Martin DH,Belland RJ

更新日期：2014-06-03 00:00:00

abstract：:Vaccination remains a major tool for prevention and progression of Johne's disease, a chronic enteritis of ruminants worldwide. Currently there is only one licensed vaccine within the United States and two vaccines licensed internationally against Johne's disease. All licensed vaccines reduce fecal shedding of Mycobac...

journal_title：Frontiers in cellular and infection microbiology

authors： Lamont EA,Talaat AM,Coussens PM,Bannantine JP,Grohn YT,Katani R,Li LL,Kapur V,Sreevatsan S

更新日期：2014-06-30 00:00:00

abstract：:Chronic otitis media with effusion (COME) is a common childhood disease characterized by an accumulation of fluid behind the eardrum. COME often requires surgical intervention and can also lead to significant hearing loss and subsequent learning disabilities. Recent characterization of the middle ear fluid (MEF) micro...

journal_title：Frontiers in cellular and infection microbiology

authors： Kolbe AR,Castro-Nallar E,Preciado D,Pérez-Losada M

更新日期：2019-10-04 00:00:00

abstract：:Enterobacteriaceae cause different types of community- and hospital-acquired infections. Moreover, the spread of multidrug-resistant Enterobacteriaceae is a public health problem and the World Health Organization pointed them among the pathogens in which the search of new antibiotics is critical. The objective of this...

journal_title：Frontiers in cellular and infection microbiology

authors： Cebrero-Cangueiro T,Álvarez-Marín R,Labrador-Herrera G,Smani Y,Cordero-Matía E,Pachón J,Pachón-Ibáñez ME

更新日期：2018-10-18 00:00:00